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Benign neoplasm of tongue

MedGen UID:
57573
•Concept ID:
C0153933
•
Neoplastic Process
Synonyms: Benign Neoplasm of the Tongue; benign neoplasm of the tongue; Benign Neoplasm of Tongue; benign neoplasm of tongue; Benign Tongue Neoplasm; benign tongue neoplasm; Benign Tongue Tumor; benign tongue tumor; benign tongue tumour; Benign Tumor of the Tongue; benign tumor of the tongue; Benign tumor of tongue; Benign Tumor of Tongue; benign tumor of tongue; benign tumour of the tongue; benign tumour of tongue; tongue benign neoplasm; Tongue Neoplasm, Benign; tongue neoplasm, benign
SNOMED CT: Benign tumor of tongue (92443005); Benign neoplasm of tongue (92443005)
 
Monarch Initiative: MONDO:0021476

Definition

A neoplasm that arises from the tongue and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign neoplasm of tongue

Professional guidelines

PubMed

Pathogenesis and Treatment of Pancreatic Cancer Related Pain.
Lohse I, Brothers SP
Anticancer Res 2020 Apr;40(4):1789-1796. doi: 10.21873/anticanres.14133. PMID: 32234867Free PMC Article
Oral lichen planus - Differential diagnoses, serum autoantibodies, hematinic deficiencies, and management.
Chiang CP, Yu-Fong Chang J, Wang YP, Wu YH, Lu SY, Sun A
J Formos Med Assoc 2018 Sep;117(9):756-765. Epub 2018 Feb 19 doi: 10.1016/j.jfma.2018.01.021. PMID: 29472048
Diagnosis and Treatment of Pituitary Adenomas: A Review.
Molitch ME
JAMA 2017 Feb 7;317(5):516-524. doi: 10.1001/jama.2016.19699. PMID: 28170483

Recent clinical studies

Etiology

In-depth metaproteomics analysis of tongue coating for gastric cancer: a multicenter diagnostic research study.
Chen J, Sun Y, Li J, Lyu M, Yuan L, Sun J, Chen S, Hu C, Wei Q, Xu Z, Guo T, Cheng X
Microbiome 2024 Jan 8;12(1):6. doi: 10.1186/s40168-023-01730-8. PMID: 38191439Free PMC Article
Oral microbiota disorder in GC patients revealed by 2b-RAD-M.
He S, Sun Y, Sun W, Tang M, Meng B, Liu Y, Kong Q, Li Y, Yu J, Li J
J Transl Med 2023 Nov 18;21(1):831. doi: 10.1186/s12967-023-04599-1. PMID: 37980457Free PMC Article
Squamous cell carcinoma of the tongue: subtypes and morphological features affecting prognosis.
Matsuo K, Akiba J, Kusukawa J, Yano H
Am J Physiol Cell Physiol 2022 Dec 1;323(6):C1611-C1623. Epub 2022 Oct 17 doi: 10.1152/ajpcell.00098.2022. PMID: 36252129
Case of squamous cell carcinoma of the tongue in a pregnant woman, with literature review.
Alramadhan SA, Fitzpatrick SG, Kim K, Cohen DM, Bhattacharyya I, Islam MN
Quintessence Int 2021 Mar 3;52(4):340-346. doi: 10.3290/j.qi.b912637. PMID: 33491384
Pediatric lingual and other intraoral lesions.
Kulbersh BD, Wiatrak BJ
Otolaryngol Clin North Am 2015 Feb;48(1):175-90. doi: 10.1016/j.otc.2014.09.012. PMID: 25439554

Diagnosis

In-depth metaproteomics analysis of tongue coating for gastric cancer: a multicenter diagnostic research study.
Chen J, Sun Y, Li J, Lyu M, Yuan L, Sun J, Chen S, Hu C, Wei Q, Xu Z, Guo T, Cheng X
Microbiome 2024 Jan 8;12(1):6. doi: 10.1186/s40168-023-01730-8. PMID: 38191439Free PMC Article
Squamous cell carcinoma of the tongue: subtypes and morphological features affecting prognosis.
Matsuo K, Akiba J, Kusukawa J, Yano H
Am J Physiol Cell Physiol 2022 Dec 1;323(6):C1611-C1623. Epub 2022 Oct 17 doi: 10.1152/ajpcell.00098.2022. PMID: 36252129
Lymphangioma Of Tongue.
Bajpai M, Pardhe N, Kumar M
J Ayub Med Coll Abbottabad 2018 Jan-Mar;30(1):146. PMID: 29504356
Angiokeratoma of Tongue.
Bakshi SS
J Pediatr Hematol Oncol 2017 Jul;39(5):407. doi: 10.1097/MPH.0000000000000748. PMID: 28060116
Lymphangioma of tongue.
Ganigara A, Ravishankar CK, Ramavakoda CY
Indian Pediatr 2015 Feb;52(2):176. doi: 10.1007/s13312-015-0602-5. PMID: 25691206

Therapy

Human papillomavirus vaccine efficacy against invasive, HPV-positive cancers: population-based follow-up of a cluster-randomised trial.
Lehtinen M, Lagheden C, Luostarinen T, Eriksson T, Apter D, Bly A, Gray P, Harjula K, Heikkilä K, Hokkanen M, Karttunen H, Kuortti M, Nieminen P, Nummela M, Paavonen J, Palmroth J, Petäjä T, Pukkala E, Soderlund-Strand A, Veivo U, Dillner J
BMJ Open 2021 Dec 30;11(12):e050669. doi: 10.1136/bmjopen-2021-050669. PMID: 35149535Free PMC Article
Do Gut Microbes Taste?
Leung R, Covasa M
Nutrients 2021 Jul 27;13(8) doi: 10.3390/nu13082581. PMID: 34444741Free PMC Article
Radiotherapy versus transoral robotic surgery and neck dissection for oropharyngeal squamous cell carcinoma (ORATOR): an open-label, phase 2, randomised trial.
Nichols AC, Theurer J, Prisman E, Read N, Berthelet E, Tran E, Fung K, de Almeida JR, Bayley A, Goldstein DP, Hier M, Sultanem K, Richardson K, Mlynarek A, Krishnan S, Le H, Yoo J, MacNeil SD, Winquist E, Hammond JA, Venkatesan V, Kuruvilla S, Warner A, Mitchell S, Chen J, Corsten M, Johnson-Obaseki S, Eapen L, Odell M, Parker C, Wehrli B, Kwan K, Palma DA
Lancet Oncol 2019 Oct;20(10):1349-1359. Epub 2019 Aug 12 doi: 10.1016/S1470-2045(19)30410-3. PMID: 31416685
Lymphangioma of tongue.
Ganigara A, Ravishankar CK, Ramavakoda CY
Indian Pediatr 2015 Feb;52(2):176. doi: 10.1007/s13312-015-0602-5. PMID: 25691206
Tongue strength and exercise in healthy individuals and in head and neck cancer patients.
Lazarus C
Semin Speech Lang 2006 Nov;27(4):260-7. doi: 10.1055/s-2006-955116. PMID: 17117352

Prognosis

Squamous cell carcinoma of the tongue: subtypes and morphological features affecting prognosis.
Matsuo K, Akiba J, Kusukawa J, Yano H
Am J Physiol Cell Physiol 2022 Dec 1;323(6):C1611-C1623. Epub 2022 Oct 17 doi: 10.1152/ajpcell.00098.2022. PMID: 36252129
Case of squamous cell carcinoma of the tongue in a pregnant woman, with literature review.
Alramadhan SA, Fitzpatrick SG, Kim K, Cohen DM, Bhattacharyya I, Islam MN
Quintessence Int 2021 Mar 3;52(4):340-346. doi: 10.3290/j.qi.b912637. PMID: 33491384
Perineural Invasion and Perineural Tumor Spread in Head and Neck Cancer.
Bakst RL, Glastonbury CM, Parvathaneni U, Katabi N, Hu KS, Yom SS
Int J Radiat Oncol Biol Phys 2019 Apr 1;103(5):1109-1124. Epub 2018 Dec 15 doi: 10.1016/j.ijrobp.2018.12.009. PMID: 30562546
Pediatric lingual and other intraoral lesions.
Kulbersh BD, Wiatrak BJ
Otolaryngol Clin North Am 2015 Feb;48(1):175-90. doi: 10.1016/j.otc.2014.09.012. PMID: 25439554
Oral submucous fibrosis.
Paissat DK
Int J Oral Surg 1981 Oct;10(5):307-12. doi: 10.1016/s0300-9785(81)80026-9. PMID: 6807916

Clinical prediction guides

In-depth metaproteomics analysis of tongue coating for gastric cancer: a multicenter diagnostic research study.
Chen J, Sun Y, Li J, Lyu M, Yuan L, Sun J, Chen S, Hu C, Wei Q, Xu Z, Guo T, Cheng X
Microbiome 2024 Jan 8;12(1):6. doi: 10.1186/s40168-023-01730-8. PMID: 38191439Free PMC Article
Squamous cell carcinoma of the tongue: subtypes and morphological features affecting prognosis.
Matsuo K, Akiba J, Kusukawa J, Yano H
Am J Physiol Cell Physiol 2022 Dec 1;323(6):C1611-C1623. Epub 2022 Oct 17 doi: 10.1152/ajpcell.00098.2022. PMID: 36252129
Modification of the anterior-posterior tongue rotation flap for oral tongue reconstruction.
Lu J, Chen Y, Xia RH, Shen Y, Zheng Z, Sun J
Head Neck 2020 Dec;42(12):3769-3775. Epub 2020 Aug 6 doi: 10.1002/hed.26409. PMID: 32767540
Chondroma of the Tongue.
Dimitrijevic MV, Sopta J, Ivisevic TB, Dudvarski Z
J Craniofac Surg 2019 Jun;30(4):e315-e317. doi: 10.1097/SCS.0000000000005230. PMID: 30845089
Nodal metastases: predictive factors.
Kowalski LP, Medina JE
Otolaryngol Clin North Am 1998 Aug;31(4):621-37. doi: 10.1016/s0030-6665(05)70076-1. PMID: 9687325

Recent systematic reviews

Margin distance in oral tongue cancer surgery: A systematic review of survival and recurrence outcomes.
Spence RN, Efthymiou V, Goss D, Varvares MA
Oral Oncol 2023 Dec;147:106609. Epub 2023 Nov 8 doi: 10.1016/j.oraloncology.2023.106609. PMID: 37948894
Swallowing exercises for head and neck cancer patients: A systematic review and meta-analysis of randomized control trials.
Banda KJ, Chu H, Kao CC, Voss J, Chiu HL, Chang PC, Chen R, Chou KR
Int J Nurs Stud 2021 Feb;114:103827. Epub 2020 Nov 11 doi: 10.1016/j.ijnurstu.2020.103827. PMID: 33352439
Human papillomavirus infection and oral squamous cell carcinoma - a systematic review.
Melo BAC, Vilar LG, Oliveira NR, Lima PO, Pinheiro MB, Domingueti CP, Pereira MC
Braz J Otorhinolaryngol 2021 May-Jun;87(3):346-352. Epub 2020 Nov 29 doi: 10.1016/j.bjorl.2020.10.017. PMID: 33339760Free PMC Article
Age and risk of recurrence in oral tongue squamous cell carcinoma: Systematic review.
Lenze NR, Farquhar DR, Dorismond C, Sheth S, Zevallos JP, Blumberg J, Lumley C, Patel S, Hackman T, Weissler MC, Yarbrough WG, Olshan AF, Zanation AM
Head Neck 2020 Dec;42(12):3755-3768. Epub 2020 Sep 11 doi: 10.1002/hed.26464. PMID: 32914472
Speech and swallow rehabilitation following partial glossectomy: a systematic review.
Blyth KM, McCabe P, Madill C, Ballard KJ
Int J Speech Lang Pathol 2015;17(4):401-10. Epub 2014 Dec 17 doi: 10.3109/17549507.2014.979880. PMID: 25515427

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