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Aphagia

MedGen UID:
526252
•Concept ID:
C0221470
•
Finding
Synonym: Unable to Eat
SNOMED CT: Aphagia (60818005)

Definition

The inability or refusal to swallow. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAphagia

Professional guidelines

PubMed

Malignant esophageal stricture and fistula: palliative treatment with polyurethane-covered Gianturco stent.
Miyayama S, Matsui O, Kadoya M, Yoshikawa J, Gabata T, Kitagawa K, Arai K, Takashima T
J Vasc Interv Radiol 1995 Mar-Apr;6(2):243-8. doi: 10.1016/s1051-0443(95)71105-8. PMID: 7540443
Lower esophageal ring: experiences in treatment of 88 patients.
Eastridge CE, Pate JW, Mann JA
Ann Thorac Surg 1984 Feb;37(2):103-7. doi: 10.1016/s0003-4975(10)60294-9. PMID: 6696542
Symptomatic lower esophageal ring: treatment of 24 patients.
Eastridge CE, Salazar J, Pate JW, Farrell G
South Med J 1979 Aug;72(8):919-21, 926. doi: 10.1097/00007611-197908000-00006. PMID: 472813

Recent clinical studies

Etiology

Dyslipidemia in patients with amyotrophic lateral sclerosis - a case control retrospective study.
Chełstowska B, Barańczyk-Kuźma A, Kuźma-Kozakiewicz M
Amyotroph Lateral Scler Frontotemporal Degener 2021 May;22(3-4):195-205. Epub 2020 Oct 26 doi: 10.1080/21678421.2020.1832119. PMID: 33103950
The over-the-scope grasper (OTSG).
Brand M, Hofmann N, Ho CN, Meining A
Endoscopy 2021 Feb;53(2):152-155. Epub 2020 Jul 14 doi: 10.1055/a-1187-0178. [Epub ahead of print] PMID: 32458998
Assessing stroke severity using electronic health record data: a machine learning approach.
Kogan E, Twyman K, Heap J, Milentijevic D, Lin JH, Alberts M
BMC Med Inform Decis Mak 2020 Jan 8;20(1):8. doi: 10.1186/s12911-019-1010-x. PMID: 31914991Free PMC Article
Digestive tract reconstitution after failed esophago-gastro or esophago-coloanastomosis.
Braghetto I, Cardemil G, Csendes A, Venturelli A, Herrera M, Korn O, Sepúlveda S, Rojas J
Arq Bras Cir Dig 2013 Jan-Mar;26(1):7-12. doi: 10.1590/s0102-67202013000100003. PMID: 23702863
Endoscopic lumen restoration for obstructive aphagia: outcomes of a 25-year experience.
Boyce HW, Estores DS, Gaziano J, Padhya T, Runk J
Gastrointest Endosc 2012 Jul;76(1):25-31. Epub 2012 Apr 5 doi: 10.1016/j.gie.2012.02.037. PMID: 22482914

Diagnosis

Revisional Surgery: Aphagia After Gastric Bypass.
Palermo M, Duza G, Serra E
J Laparoendosc Adv Surg Tech A 2020 Aug;30(8):887-890. Epub 2020 Apr 29 doi: 10.1089/lap.2020.0203. PMID: 32352889
Assessing stroke severity using electronic health record data: a machine learning approach.
Kogan E, Twyman K, Heap J, Milentijevic D, Lin JH, Alberts M
BMC Med Inform Decis Mak 2020 Jan 8;20(1):8. doi: 10.1186/s12911-019-1010-x. PMID: 31914991Free PMC Article
Oesophageal lichen planus: the efficacy of topical steroid-based therapies.
Podboy A, Sunjaya D, Smyrk TC, Murray JA, Binder M, Katzka DA, Alexander JA, Halland M
Aliment Pharmacol Ther 2017 Jan;45(2):310-318. Epub 2016 Nov 17 doi: 10.1111/apt.13856. PMID: 27859412
Megaesophagus associated with Myasthenia Gravis: a rare condition in humans.
Desuter G, Van Parijs V, Gardiner Q
B-ENT 2015;11(1):63-6. PMID: 26513950
Acute abscess of the base of the tongue: a rare but important emergency.
Vellin JF, Crestani S, Saroul N, Bivahagumye L, Gabrillargues J, Gilain L
J Emerg Med 2011 Nov;41(5):e107-10. Epub 2008 Nov 20 doi: 10.1016/j.jemermed.2008.04.047. PMID: 19022603

Therapy

Dyslipidemia in patients with amyotrophic lateral sclerosis - a case control retrospective study.
Chełstowska B, Barańczyk-Kuźma A, Kuźma-Kozakiewicz M
Amyotroph Lateral Scler Frontotemporal Degener 2021 May;22(3-4):195-205. Epub 2020 Oct 26 doi: 10.1080/21678421.2020.1832119. PMID: 33103950
Oesophageal lichen planus: the efficacy of topical steroid-based therapies.
Podboy A, Sunjaya D, Smyrk TC, Murray JA, Binder M, Katzka DA, Alexander JA, Halland M
Aliment Pharmacol Ther 2017 Jan;45(2):310-318. Epub 2016 Nov 17 doi: 10.1111/apt.13856. PMID: 27859412
Endoscopic lumen restoration for obstructive aphagia: outcomes of a 25-year experience.
Boyce HW, Estores DS, Gaziano J, Padhya T, Runk J
Gastrointest Endosc 2012 Jul;76(1):25-31. Epub 2012 Apr 5 doi: 10.1016/j.gie.2012.02.037. PMID: 22482914
Acute abscess of the base of the tongue: a rare but important emergency.
Vellin JF, Crestani S, Saroul N, Bivahagumye L, Gabrillargues J, Gilain L
J Emerg Med 2011 Nov;41(5):e107-10. Epub 2008 Nov 20 doi: 10.1016/j.jemermed.2008.04.047. PMID: 19022603
Twenty-five years of amantadine therapy in Parkinson's disease.
Danielczyk W
J Neural Transm Suppl 1995;46:399-405. PMID: 8821075

Prognosis

Exogenous leptin promotes reproductive behavior during aphagia in red-sided garter snakes (Thamnophis sirtalis parietalis).
Wilson RC, LeMaster MP, Lutterschmidt DI
Horm Behav 2021 Feb;128:104893. Epub 2020 Dec 24 doi: 10.1016/j.yhbeh.2020.104893. PMID: 33333076
Assessing stroke severity using electronic health record data: a machine learning approach.
Kogan E, Twyman K, Heap J, Milentijevic D, Lin JH, Alberts M
BMC Med Inform Decis Mak 2020 Jan 8;20(1):8. doi: 10.1186/s12911-019-1010-x. PMID: 31914991Free PMC Article
An analysis of prognostic factors after percutaneous endoscopic gastrostomy placement in Japanese patients with amyotrophic lateral sclerosis.
Nagashima K, Furuta N, Makioka K, Fujita Y, Ikeda M, Ikeda Y
J Neurol Sci 2017 May 15;376:202-205. Epub 2017 Mar 21 doi: 10.1016/j.jns.2017.03.029. PMID: 28431613
Re-operation for failed gastro-esophageal fundoplication. What results to expect?
Vignal JC, Luc G, Wagner T, Cunha AS, Collet D
J Visc Surg 2012 Feb;149(1):e61-5. Epub 2012 Feb 6 doi: 10.1016/j.jviscsurg.2011.12.004. PMID: 22317929
Acute deterioration of bulbar function after botulinum toxin treatment for sialorrhoea in amyotrophic lateral sclerosis.
Meijer JW, van Kuijk AA, Geurts AC, Schelhaas HJ, Zwarts MJ
Am J Phys Med Rehabil 2008 Apr;87(4):321-4. doi: 10.1097/PHM.0b013e318164a931. PMID: 18303472

Clinical prediction guides

Revisional Surgery: Aphagia After Gastric Bypass.
Palermo M, Duza G, Serra E
J Laparoendosc Adv Surg Tech A 2020 Aug;30(8):887-890. Epub 2020 Apr 29 doi: 10.1089/lap.2020.0203. PMID: 32352889
Assessing stroke severity using electronic health record data: a machine learning approach.
Kogan E, Twyman K, Heap J, Milentijevic D, Lin JH, Alberts M
BMC Med Inform Decis Mak 2020 Jan 8;20(1):8. doi: 10.1186/s12911-019-1010-x. PMID: 31914991Free PMC Article
Oesophageal lichen planus: the efficacy of topical steroid-based therapies.
Podboy A, Sunjaya D, Smyrk TC, Murray JA, Binder M, Katzka DA, Alexander JA, Halland M
Aliment Pharmacol Ther 2017 Jan;45(2):310-318. Epub 2016 Nov 17 doi: 10.1111/apt.13856. PMID: 27859412
Digestive tract reconstitution after failed esophago-gastro or esophago-coloanastomosis.
Braghetto I, Cardemil G, Csendes A, Venturelli A, Herrera M, Korn O, Sepúlveda S, Rojas J
Arq Bras Cir Dig 2013 Jan-Mar;26(1):7-12. doi: 10.1590/s0102-67202013000100003. PMID: 23702863
Twenty-five years of amantadine therapy in Parkinson's disease.
Danielczyk W
J Neural Transm Suppl 1995;46:399-405. PMID: 8821075

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