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Obstipation

MedGen UID:
526173
Concept ID:
C0221152
Disease or Syndrome
Synonyms: Intractable constipation; Lack of flatulence; No gas passage; Tympanic distended abdomen
SNOMED CT: Obstipation (111360009); Intractable constipation (111360009)
 
HPO: HP:0034782

Definition

Obstipation is the inability to pass either stool or flatus (gas). [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVObstipation

Professional guidelines

PubMed

Colombel JF, Shin A, Gibson PR
Clin Gastroenterol Hepatol 2019 Feb;17(3):380-390.e1. Epub 2018 Aug 9 doi: 10.1016/j.cgh.2018.08.001. PMID: 30099108Free PMC Article
Rami Reddy SR, Cappell MS
Curr Gastroenterol Rep 2017 Jun;19(6):28. doi: 10.1007/s11894-017-0566-9. PMID: 28439845
Irani S, Kozarek RA
Curr Opin Gastroenterol 2015 Sep;31(5):339-50. doi: 10.1097/MOG.0000000000000200. PMID: 26247823

Recent clinical studies

Etiology

Rami Reddy SR, Cappell MS
Curr Gastroenterol Rep 2017 Jun;19(6):28. doi: 10.1007/s11894-017-0566-9. PMID: 28439845
Khalayleh H, Koplewitz BZ, Kapuller V, Armon Y, Abu-Leil S, Arbell D
J Pediatr Surg 2016 Nov;51(11):1782-1785. Epub 2016 Jul 5 doi: 10.1016/j.jpedsurg.2016.06.017. PMID: 27444245
de Vrese M, Schrezenmeir J
Adv Biochem Eng Biotechnol 2008;111:1-66. doi: 10.1007/10_2008_097. PMID: 18461293
Kloeppel R, Rothe K, Hoermann D, Schmidt F, Bennek J, Kahn T
J Comput Assist Tomogr 2002 Mar-Apr;26(2):262-5. doi: 10.1097/00004728-200203000-00017. PMID: 11884784
Rintala R, Rapola J, Louhimo I
Prog Pediatr Surg 1989;24:186-92. doi: 10.1007/978-3-642-74493-8_20. PMID: 2513603

Diagnosis

Beg MY, Bains L, Lal P, Maranna H, Kumar N P
Ann R Coll Surg Engl 2020 Oct;102(8):571-576. Epub 2020 Jun 15 doi: 10.1308/rcsann.2020.0122. PMID: 32538120Free PMC Article
Colombel JF, Shin A, Gibson PR
Clin Gastroenterol Hepatol 2019 Feb;17(3):380-390.e1. Epub 2018 Aug 9 doi: 10.1016/j.cgh.2018.08.001. PMID: 30099108Free PMC Article
Rami Reddy SR, Cappell MS
Curr Gastroenterol Rep 2017 Jun;19(6):28. doi: 10.1007/s11894-017-0566-9. PMID: 28439845
Khalayleh H, Koplewitz BZ, Kapuller V, Armon Y, Abu-Leil S, Arbell D
J Pediatr Surg 2016 Nov;51(11):1782-1785. Epub 2016 Jul 5 doi: 10.1016/j.jpedsurg.2016.06.017. PMID: 27444245
Stillman M, Tailor M
N Engl J Med 2013 Nov 14;369(20):1880-1. Epub 2013 Oct 23 doi: 10.1056/NEJMp1312793. PMID: 24152232

Therapy

Gullaksen S, Vernstrøm L, Sørensen SS, Ringgaard S, Laustsen C, Funck KL, Poulsen PL, Laugesen E
Diabetologia 2023 May;66(5):813-825. Epub 2023 Feb 6 doi: 10.1007/s00125-023-05876-w. PMID: 36746803
Van Grootven B, Jeuris A, Jonckers M, Devriendt E, Dierckx de Casterlé B, Dubois C, Fagard K, Herregods MC, Hornikx M, Meuris B, Rex S, Tournoy J, Milisen K, Flamaing J, Deschodt M
J Am Geriatr Soc 2021 May;69(5):1377-1387. Epub 2021 Mar 17 doi: 10.1111/jgs.17093. PMID: 33730373
Barreiros AP, Galle PR, Otto G
Dig Dis 2013;31(1):170-4. Epub 2013 Jun 17 doi: 10.1159/000347214. PMID: 23797140
de Vrese M, Schrezenmeir J
Adv Biochem Eng Biotechnol 2008;111:1-66. doi: 10.1007/10_2008_097. PMID: 18461293
Golzarian J, Scott HW Jr, Richards WO
Dig Dis Sci 1994 May;39(5):1138-42. doi: 10.1007/BF02087570. PMID: 8174429

Prognosis

Khalayleh H, Koplewitz BZ, Kapuller V, Armon Y, Abu-Leil S, Arbell D
J Pediatr Surg 2016 Nov;51(11):1782-1785. Epub 2016 Jul 5 doi: 10.1016/j.jpedsurg.2016.06.017. PMID: 27444245
Stillman M, Tailor M
N Engl J Med 2013 Nov 14;369(20):1880-1. Epub 2013 Oct 23 doi: 10.1056/NEJMp1312793. PMID: 24152232
Cappell MS, Batke M
Med Clin North Am 2008 May;92(3):575-97, viii. doi: 10.1016/j.mcna.2008.01.003. PMID: 18387377
Milla PJ
Baillieres Clin Gastroenterol 1998 Dec;12(4):775-97. doi: 10.1016/s0950-3528(98)90007-0. PMID: 10079906
Rintala R, Rapola J, Louhimo I
Prog Pediatr Surg 1989;24:186-92. doi: 10.1007/978-3-642-74493-8_20. PMID: 2513603

Clinical prediction guides

Stritter W, Rutert B, Eggert A, Längler A, Holmberg C, Seifert G
Integr Cancer Ther 2020 Jan-Dec;19:1534735420928393. doi: 10.1177/1534735420928393. PMID: 32646250Free PMC Article
Neville JJ, Gallagher J, Mitra A, Sheth H
World J Surg 2020 Jun;44(6):1771-1778. doi: 10.1007/s00268-020-05403-7. PMID: 32030442
Brunoni AR, Moffa AH, Sampaio-Junior B, Borrione L, Moreno ML, Fernandes RA, Veronezi BP, Nogueira BS, Aparicio LVM, Razza LB, Chamorro R, Tort LC, Fraguas R, Lotufo PA, Gattaz WF, Fregni F, Benseñor IM; ELECT-TDCS Investigators
N Engl J Med 2017 Jun 29;376(26):2523-2533. doi: 10.1056/NEJMoa1612999. PMID: 28657871
Wolf H
Scand J Rheumatol Suppl 2000;113:37-45. doi: 10.1080/030097400446625. PMID: 11028830
Shafer RB, Prentiss RA, Bond JH
Gastroenterology 1984 May;86(5 Pt 1):852-5. PMID: 6706068

Recent systematic reviews

Mørdre M, Ørbeck B, Hoel RE, Øvergaard KR
Tidsskr Nor Laegeforen 2024 Nov 26;144(14) Epub 2024 Nov 11 doi: 10.4045/tidsskr.24.0193. PMID: 39605156
Augustin G, Bruketa T, Kunjko K, Romić I, Mikuš M, Vrbanić A, Tropea A
Updates Surg 2023 Aug;75(5):1071-1082. Epub 2023 May 20 doi: 10.1007/s13304-023-01537-0. PMID: 37209317
Neville JJ, Gallagher J, Mitra A, Sheth H
World J Surg 2020 Jun;44(6):1771-1778. doi: 10.1007/s00268-020-05403-7. PMID: 32030442
Rami Reddy SR, Cappell MS
Curr Gastroenterol Rep 2017 Jun;19(6):28. doi: 10.1007/s11894-017-0566-9. PMID: 28439845

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