U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Substance Abuse, Intravenous

MedGen UID:
52537
•Concept ID:
C0038579
•
Mental or Behavioral Dysfunction
Synonym: Intravenous Substance Abuse

Definition

Abuse, overuse, or misuse of a substance by its injection into a vein. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSubstance Abuse, Intravenous

Professional guidelines

PubMed

Consensus recommendations on the management of hepatitis C in Australia's prisons.
Winter RJ, Sheehan Y, Papaluca T, Macdonald GA, Rowland J, Colman A, Stoove M, Lloyd AR, Thompson AJ
Med J Aust 2023 Mar 20;218(5):231-237. Epub 2023 Mar 5 doi: 10.5694/mja2.51854. PMID: 36871200
Management of Infective Endocarditis in People Who Inject Drugs: A Scientific Statement From the American Heart Association.
Baddour LM, Weimer MB, Wurcel AG, McElhinney DB, Marks LR, Fanucchi LC, Esquer Garrigos Z, Pettersson GB, DeSimone DC; American Heart Association Rheumatic Fever, Endocarditis and Kawasaki Disease Committee of the Council on Lifelong Congenital Heart Disease and Heart Health in the Young; Council on Cardiovascular Surgery and Anesthesia; Council on Cardiovascular and Stroke Nursing; Council on Clinical Cardiology; and Council on Peripheral Vascular Disease
Circulation 2022 Oct 4;146(14):e187-e201. Epub 2022 Aug 31 doi: 10.1161/CIR.0000000000001090. PMID: 36043414
Challenges Facing a Rural Opioid Epidemic: Treatment and Prevention of HIV and Hepatitis C.
Schranz AJ, Barrett J, Hurt CB, Malvestutto C, Miller WC
Curr HIV/AIDS Rep 2018 Jun;15(3):245-254. doi: 10.1007/s11904-018-0393-0. PMID: 29796965Free PMC Article

Recent clinical studies

Etiology

Infective endocarditis in intravenous drug users: a review article.
Colville T, Sharma V, Albouaini K
Postgrad Med J 2016 Feb;92(1084):105-11. Epub 2015 Dec 30 doi: 10.1136/postgradmedj-2015-133648. PMID: 26719453
Abuse of inhalants: a review.
Dinwiddie SH
Addiction 1994 Aug;89(8):925-39. doi: 10.1111/j.1360-0443.1994.tb03348.x. PMID: 7950851
Opiate treatments.
Johns A
Addiction 1994 Nov;89(11):1551-8. doi: 10.1111/j.1360-0443.1994.tb03757.x. PMID: 7841870
Drug-related death--an update.
Püschel K
Forensic Sci Int 1993 Nov;62(1-2):121-8. doi: 10.1016/0379-0738(93)90056-g. PMID: 8300023
Risky business.
Pauker SG, Kopelman RI
N Engl J Med 1992 Jun 4;326(23):1546-9. doi: 10.1056/NEJM199206043262307. PMID: 1579138

Diagnosis

Serratia marcescens Endocarditis.
Oliver T, Vazquez J
J Investig Med High Impact Case Rep 2023 Jan-Dec;11:23247096231222414. doi: 10.1177/23247096231222414. PMID: 38146713Free PMC Article
"String-of-pearls".
Lo JS, Lo JO, Hunter AJ
J Hosp Med 2008 May;3(3):272-3. doi: 10.1002/jhm.305. PMID: 18571810
Developing a plan of care using the Roper, Logan and Tierney model.
Mooney M, O'Brien F
Br J Nurs 2006 Sep 14-27;15(16):887-92. doi: 10.12968/bjon.2006.15.16.21854. PMID: 17108861
Self-inflicted pneumothoraces.
Urschel JD, Miller JD, Bennett WF
Ann Thorac Surg 2001 Jul;72(1):280-1. doi: 10.1016/s0003-4975(00)02529-7. PMID: 11465205
Talc retinopathy.
O'Brien RJ, Schroedl BL
Optom Vis Sci 1991 Jan;68(1):54-7. doi: 10.1097/00006324-199101000-00009. PMID: 2023717

Therapy

Surgical timing in infective endocarditis complicated by intracranial hemorrhage.
Venn RA, Ning M, Vlahakes GJ, Wasfy JH
Am Heart J 2019 Oct;216:102-112. Epub 2019 Jul 23 doi: 10.1016/j.ahj.2019.07.011. PMID: 31422194
Behavioral and biomedical combination strategies for HIV prevention.
Bekker LG, Beyrer C, Quinn TC
Cold Spring Harb Perspect Med 2012 Aug 1;2(8) doi: 10.1101/cshperspect.a007435. PMID: 22908192Free PMC Article
HIV treatment as prevention among injection drug users.
Wood E, Milloy MJ, Montaner JS
Curr Opin HIV AIDS 2012 Mar;7(2):151-6. doi: 10.1097/COH.0b013e32834f9927. PMID: 22227587
Vaccine immunogenicity in injecting drug users: a systematic review.
Baral S, Sherman SG, Millson P, Beyrer C
Lancet Infect Dis 2007 Oct;7(10):667-74. doi: 10.1016/S1473-3099(07)70237-2. PMID: 17897609
Pharmacological and clinical evidences on the potential for abuse and dependence of propofol: a review of the literature.
Roussin A, Montastruc JL, Lapeyre-Mestre M
Fundam Clin Pharmacol 2007 Oct;21(5):459-66. doi: 10.1111/j.1472-8206.2007.00497.x. PMID: 17868199

Prognosis

Incidence of hepatitis C virus infection in the prison setting: The SToP-C study.
Hajarizadeh B, Carson JM, Byrne M, Grebely J, Cunningham E, Amin J, Vickerman P, Martin NK, Treloar C, Martinello M, Lloyd AR, Dore GJ; SToP-C study group
J Viral Hepat 2024 Jan;31(1):21-34. Epub 2023 Nov 7 doi: 10.1111/jvh.13895. PMID: 37936544Free PMC Article
Understanding and addressing hepatitis C reinfection in the oral direct-acting antiviral era.
Falade-Nwulia O, Sulkowski MS, Merkow A, Latkin C, Mehta SH
J Viral Hepat 2018 Mar;25(3):220-227. doi: 10.1111/jvh.12859. PMID: 29316030Free PMC Article
Epidemiology of hepatitis C virus infection.
Alter MJ
World J Gastroenterol 2007 May 7;13(17):2436-41. doi: 10.3748/wjg.v13.i17.2436. PMID: 17552026Free PMC Article
The future of the HIV pandemic.
Grassly NC, Garnett GP
Bull World Health Organ 2005 May;83(5):378-82. Epub 2005 Jun 24 PMID: 15976879Free PMC Article
Abuse of inhalants: a review.
Dinwiddie SH
Addiction 1994 Aug;89(8):925-39. doi: 10.1111/j.1360-0443.1994.tb03348.x. PMID: 7950851

Clinical prediction guides

Medical Complications of Injection Drug Use - Part I.
Rich KM, Solomon DA
NEJM Evid 2023 Feb;2(2):EVIDra2200292. Epub 2023 Jan 24 doi: 10.1056/EVIDra2200292. PMID: 38320040
Medical Complications of Injection Drug Use - Part II.
Rich KM, Solomon DA
NEJM Evid 2023 Mar;2(3):EVIDra2300019. Epub 2023 Feb 28 doi: 10.1056/EVIDra2300019. PMID: 38320028
The Preoperative Evaluation of Infective Endocarditis via 3-Dimensional Transesophageal Echocardiography.
Yong MS, Saxena P, Killu AM, Coffey S, Burkhart HM, Wan SH, Malouf JF
Tex Heart Inst J 2015 Aug;42(4):372-6. Epub 2015 Aug 1 doi: 10.14503/THIJ-14-4375. PMID: 26413022Free PMC Article
Development of a brief substance use sensation seeking scale: validation and prediction of injection-related behaviors.
Werb D, Richardson C, Buxton J, Shoveller J, Wood E, Kerr T
AIDS Behav 2015 Feb;19(2):352-61. doi: 10.1007/s10461-014-0875-z. PMID: 25119056Free PMC Article
Right-side endocarditis in injection drug users: review of proposed mechanisms of pathogenesis.
Frontera JA, Gradon JD
Clin Infect Dis 2000 Feb;30(2):374-9. doi: 10.1086/313664. PMID: 10671344

Recent systematic reviews

Supervised Injection Facilities as Harm Reduction: A Systematic Review.
Levengood TW, Yoon GH, Davoust MJ, Ogden SN, Marshall BDL, Cahill SR, Bazzi AR
Am J Prev Med 2021 Nov;61(5):738-749. Epub 2021 Jul 1 doi: 10.1016/j.amepre.2021.04.017. PMID: 34218964Free PMC Article
The global prevalence of hepatitis D virus infection: Systematic review and meta-analysis.
Stockdale AJ, Kreuels B, Henrion MYR, Giorgi E, Kyomuhangi I, de Martel C, Hutin Y, Geretti AM
J Hepatol 2020 Sep;73(3):523-532. Epub 2020 Apr 23 doi: 10.1016/j.jhep.2020.04.008. PMID: 32335166Free PMC Article
Global prevalence of injecting drug use and sociodemographic characteristics and prevalence of HIV, HBV, and HCV in people who inject drugs: a multistage systematic review.
Degenhardt L, Peacock A, Colledge S, Leung J, Grebely J, Vickerman P, Stone J, Cunningham EB, Trickey A, Dumchev K, Lynskey M, Griffiths P, Mattick RP, Hickman M, Larney S
Lancet Glob Health 2017 Dec;5(12):e1192-e1207. Epub 2017 Oct 23 doi: 10.1016/S2214-109X(17)30375-3. PMID: 29074409Free PMC Article
Supervised injection services: what has been demonstrated? A systematic literature review.
Potier C, Laprévote V, Dubois-Arber F, Cottencin O, Rolland B
Drug Alcohol Depend 2014 Dec 1;145:48-68. Epub 2014 Oct 23 doi: 10.1016/j.drugalcdep.2014.10.012. PMID: 25456324
Desomorphine goes "crocodile".
Gahr M, Freudenmann RW, Hiemke C, Gunst IM, Connemann BJ, Schönfeldt-Lecuona C
J Addict Dis 2012;31(4):407-12. doi: 10.1080/10550887.2012.735570. PMID: 23244560

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...