U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Non-restrictive ventricular septal defect

MedGen UID:
488962
•Concept ID:
C1298817
•
Disease or Syndrome
SNOMED CT: Non-restrictive ventricular septal defect (373131000)
 
HPO: HP:0011684

Definition

Any ventricular septal defect (VSD) that does not restrict flow across it sufficiently to generate a pressure gradient between the two sides of the VSD. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNon-restrictive ventricular septal defect

Professional guidelines

PubMed

Morphological, haemodynamic, and clinical variables as predictors for management of isolated ventricular septal defect.
van den Heuvel F, Timmers T, Hess J
Br Heart J 1995 Jan;73(1):49-52. doi: 10.1136/hrt.73.1.49. PMID: 7888261Free PMC Article

Recent clinical studies

Etiology

Short-Term Nutritional Support Improves The Preoperative Nutritional Status of Infants With Non-Restrictive Ventricular Septal Defect: A Prospective Controlled Study.
Xu LP, Lin SH, Zhang QL, Zheng Y, Lin G
Heart Surg Forum 2022 Oct 31;25(5):E745-E749. doi: 10.1532/hsf.5009. PMID: 36317897
Benefits of perioperative sildenafil therapy in children with a ventricular septal defect with pulmonary artery hypertension on early surgical outcomes.
Patel R, Thingnam SKS, Mishra AK, Rohit MK, Upadhyay V, Halder V, Bansal V
J Card Surg 2020 Dec;35(12):3302-3309. Epub 2020 Sep 16 doi: 10.1111/jocs.15030. PMID: 32939849
The Effect of Perioperative Administration of Treprostinil in Infants with Non-restrictive Ventricular Septal Defect and Severe Pulmonary Arterial Hypertension.
Huang ST, Xu N, Sun KP, Chen LW, Cao H, Chen Q
Pediatr Cardiol 2020 Oct;41(7):1334-1339. Epub 2020 May 28 doi: 10.1007/s00246-020-02387-y. PMID: 32468125
Morphological, haemodynamic, and clinical variables as predictors for management of isolated ventricular septal defect.
van den Heuvel F, Timmers T, Hess J
Br Heart J 1995 Jan;73(1):49-52. doi: 10.1136/hrt.73.1.49. PMID: 7888261Free PMC Article

Diagnosis

Tricuspid atresia associated with aortopulmonary window: diagnostic and therapeutic dilemmas.
Milovanovic V, Stefanovic I, Ilic S
Cardiol Young 2017 Apr;27(3):580-583. Epub 2016 Sep 29 doi: 10.1017/S1047951116001499. PMID: 27680574
Morphological, haemodynamic, and clinical variables as predictors for management of isolated ventricular septal defect.
van den Heuvel F, Timmers T, Hess J
Br Heart J 1995 Jan;73(1):49-52. doi: 10.1136/hrt.73.1.49. PMID: 7888261Free PMC Article

Therapy

Short-Term Nutritional Support Improves The Preoperative Nutritional Status of Infants With Non-Restrictive Ventricular Septal Defect: A Prospective Controlled Study.
Xu LP, Lin SH, Zhang QL, Zheng Y, Lin G
Heart Surg Forum 2022 Oct 31;25(5):E745-E749. doi: 10.1532/hsf.5009. PMID: 36317897
Benefits of perioperative sildenafil therapy in children with a ventricular septal defect with pulmonary artery hypertension on early surgical outcomes.
Patel R, Thingnam SKS, Mishra AK, Rohit MK, Upadhyay V, Halder V, Bansal V
J Card Surg 2020 Dec;35(12):3302-3309. Epub 2020 Sep 16 doi: 10.1111/jocs.15030. PMID: 32939849
The Effect of Perioperative Administration of Treprostinil in Infants with Non-restrictive Ventricular Septal Defect and Severe Pulmonary Arterial Hypertension.
Huang ST, Xu N, Sun KP, Chen LW, Cao H, Chen Q
Pediatr Cardiol 2020 Oct;41(7):1334-1339. Epub 2020 May 28 doi: 10.1007/s00246-020-02387-y. PMID: 32468125

Prognosis

Morphological, haemodynamic, and clinical variables as predictors for management of isolated ventricular septal defect.
van den Heuvel F, Timmers T, Hess J
Br Heart J 1995 Jan;73(1):49-52. doi: 10.1136/hrt.73.1.49. PMID: 7888261Free PMC Article

Clinical prediction guides

Short-Term Nutritional Support Improves The Preoperative Nutritional Status of Infants With Non-Restrictive Ventricular Septal Defect: A Prospective Controlled Study.
Xu LP, Lin SH, Zhang QL, Zheng Y, Lin G
Heart Surg Forum 2022 Oct 31;25(5):E745-E749. doi: 10.1532/hsf.5009. PMID: 36317897
Morphological, haemodynamic, and clinical variables as predictors for management of isolated ventricular septal defect.
van den Heuvel F, Timmers T, Hess J
Br Heart J 1995 Jan;73(1):49-52. doi: 10.1136/hrt.73.1.49. PMID: 7888261Free PMC Article
Natural history of the ventricular septal defect in tricuspid atresia and its surgical implications.
Rao PS
Br Heart J 1977 Mar;39(3):276-88. doi: 10.1136/hrt.39.3.276. PMID: 849388Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...