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Abnormal coronary sinus morphology

MedGen UID:
488866
•Concept ID:
C0344680
•
Congenital Abnormality
Synonyms: Abnormality of the coronary sinus; Coronary sinus abnormality; CS - Coronary sinus abnormality
SNOMED CT: Coronary sinus abnormality (253323000); CS - Coronary sinus abnormality (253323000)
 
HPO: HP:0011642

Definition

An abnormality of the coronary sinus, which is formed by the union of the great cardiac vein and the left marginal vein and terminates in the right atrium. The coronary sinus functions to o collect deoxygenated blood from the myocardium of the heart and drain it into the right atrium. [from HPO]

Professional guidelines

PubMed

International consensus statement on nomenclature and classification of the congenital bicuspid aortic valve and its aortopathy, for clinical, surgical, interventional and research purposes.
Michelena HI, Della Corte A, Evangelista A, Maleszewski JJ, Edwards WD, Roman MJ, Devereux RB, Fernández B, Asch FM, Barker AJ, Sierra-Galan LM, De Kerchove L, Fernandes SM, Fedak PWM, Girdauskas E, Delgado V, Abbara S, Lansac E, Prakash SK, Bissell MM, Popescu BA, Hope MD, Sitges M, Thourani VH, Pibarot P, Chandrasekaran K, Lancellotti P, Borger MA, Forrest JK, Webb J, Milewicz DM, Makkar R, Leon MB, Sanders SP, Markl M, Ferrari VA, Roberts WC, Song JK, Blanke P, White CS, Siu S, Svensson LG, Braverman AC, Bavaria J, Sundt TM, El Khoury G, De Paulis R, Enriquez-Sarano M, Bax JJ, Otto CM, Schäfers HJ
J Thorac Cardiovasc Surg 2021 Sep;162(3):e383-e414. Epub 2021 Jul 22 doi: 10.1016/j.jtcvs.2021.06.019. PMID: 34304896
Coronary sinus diverticulum: Importance, function, and treatment.
Razeghian-Jahromi I, Natale A, Nikoo MH
Pacing Clin Electrophysiol 2020 Dec;43(12):1582-1587. Epub 2020 Sep 4 doi: 10.1111/pace.14026. PMID: 32815147
Unroofed coronary sinus syndrome: diagnosis, classification, and surgical treatment.
Ootaki Y, Yamaguchi M, Yoshimura N, Oka S, Yoshida M, Hasegawa T
J Thorac Cardiovasc Surg 2003 Nov;126(5):1655-6. doi: 10.1016/s0022-5223(03)01019-5. PMID: 14666054

Recent clinical studies

Etiology

Characterization of unipolar electrogram morphology: a novel tool for quantifying conduction inhomogeneity.
Ye Z, van Schie MS, Pool L, Heida A, Knops P, Taverne YJHJ, Brundel BJJM, de Groot NMS
Europace 2023 Nov 2;25(11) doi: 10.1093/europace/euad324. PMID: 37931071Free PMC Article
Persistent Left Superior Vena Cava in Fetuses: An Autopsy Series.
Ramakrishnan D, Chidambarathanu S, Murli L, Micheal J, Jagadeesh S, Suresh I, Seshadri S
Fetal Pediatr Pathol 2017 Aug;36(4):304-310. Epub 2017 Jun 1 doi: 10.1080/15513815.2017.1324546. PMID: 28569558
Unroofed coronary sinus defect.
Kwok OH, Chan JK
Hong Kong Med J 2008 Aug;14(4):331-2. PMID: 18685171
Aortico-right ventricular tunnel.
Vargas FJ, Molina A, Martinez JC, Ranzini ME, Vazquez JC
Ann Thorac Surg 1998 Nov;66(5):1793-5. doi: 10.1016/s0003-4975(98)00927-8. PMID: 9875792
Anatomy of the atrioventricular junctions with regard to ventricular preexcitation.
Anderson RH, Ho SY
Pacing Clin Electrophysiol 1997 Aug;20(8 Pt 2):2072-6. doi: 10.1111/j.1540-8159.1997.tb03631.x. PMID: 9272512

Diagnosis

Cardiac magnetic resonance in the assessment of the anomalous right coronary artery originating from the left sinus of Valsalva.
Cipriani A, Lo Rito M, Pica S, De Gaspari M, Rigato I, Perazzolo Marra M, De Conti G, Corradin S, Motta R, Pergola V, Secchi F, Lombardi M, Bauce B, Zorzi A, Thiene G, Basso C, Molossi S, Padalino MA, Corrado D
Eur Heart J 2024 Jun 14;45(23):2098-2100. doi: 10.1093/eurheartj/ehae129. PMID: 38442289
Identifying Anomalies of Systemic Venous Drainage: Systemic Venous Anomalies; Atrial Morphology.
Maddali MM, Al Kindi HN, Kandachar PS, Al Farqani A, Al Alawi KS, Al Kindi F, Al-Maskari SN, Spicer DE, Anderson RH
World J Pediatr Congenit Heart Surg 2023 Jul;14(4):490-496. Epub 2023 Mar 15 doi: 10.1177/21501351231158539. PMID: 36921325
Primary-care management of patients with congenital anomalies of the coronary arteries.
Boris JR, Brothers JA
Cardiol Young 2015 Dec;25(8):1540-5. doi: 10.1017/S1047951115002127. PMID: 26675602
Giant coronary sinus.
Nathani S, Parakh N, Chaturvedi V, Tyagi S
Tex Heart Inst J 2011;38(3):310-1. PMID: 21720482Free PMC Article
Aortico-right ventricular tunnel.
Vargas FJ, Molina A, Martinez JC, Ranzini ME, Vazquez JC
Ann Thorac Surg 1998 Nov;66(5):1793-5. doi: 10.1016/s0003-4975(98)00927-8. PMID: 9875792

Therapy

Anomalous right coronary artery from the left sinus with interarterial course.
Marcos-Garcés V, Lorenzo-Hernández M, Martínez ML, Parrilla Muñoz C, Pernias V, Bodi V
Coron Artery Dis 2021 Aug 1;32(5):475-477. doi: 10.1097/MCA.0000000000000941. PMID: 32804784
Extracardiac Rerouting of Left Superior Vena Cava to Right Atrium.
Rudrappa SC, Aggarwal N, Joshi R, Joshi R
Semin Thorac Cardiovasc Surg 2019 Autumn;31(3):571-572. Epub 2019 Apr 19 doi: 10.1053/j.semtcvs.2019.04.009. PMID: 31005577
Acquired and congenital coronary artery abnormalities.
Young ML, McLeary M, Chan KC
Cardiol Young 2017 Jan;27(S1):S31-S35. doi: 10.1017/S1047951116002201. PMID: 28084958
Development and validation of an ECG algorithm for identifying accessory pathway ablation site in Wolff-Parkinson-White syndrome.
Arruda MS, McClelland JH, Wang X, Beckman KJ, Widman LE, Gonzalez MD, Nakagawa H, Lazzara R, Jackman WM
J Cardiovasc Electrophysiol 1998 Jan;9(1):2-12. doi: 10.1111/j.1540-8167.1998.tb00861.x. PMID: 9475572
Diagnostic and therapeutic aspects of stable angina pectoris.
Myerburg RJ
Med Clin North Am 1971 Mar;55(2):421-33. doi: 10.1016/s0025-7125(16)32529-9. PMID: 4396019

Prognosis

Separate right sinus origin of right coronary artery, conus artery and anomalous left main with retroaortic course.
Sharma A, Jaswal V, Singhal M
Coron Artery Dis 2023 May 1;34(3):220. Epub 2023 Feb 28 doi: 10.1097/MCA.0000000000001231. PMID: 36951752
International consensus statement on nomenclature and classification of the congenital bicuspid aortic valve and its aortopathy, for clinical, surgical, interventional and research purposes.
Michelena HI, Della Corte A, Evangelista A, Maleszewski JJ, Edwards WD, Roman MJ, Devereux RB, Fernández B, Asch FM, Barker AJ, Sierra-Galan LM, De Kerchove L, Fernandes SM, Fedak PWM, Girdauskas E, Delgado V, Abbara S, Lansac E, Prakash SK, Bissell MM, Popescu BA, Hope MD, Sitges M, Thourani VH, Pibarot P, Chandrasekaran K, Lancellotti P, Borger MA, Forrest JK, Webb J, Milewicz DM, Makkar R, Leon MB, Sanders SP, Markl M, Ferrari VA, Roberts WC, Song JK, Blanke P, White CS, Siu S, Svensson LG, Braverman AC, Bavaria J, Sundt TM, El Khoury G, De Paulis R, Enriquez-Sarano M, Bax JJ, Otto CM, Schäfers HJ
J Thorac Cardiovasc Surg 2021 Sep;162(3):e383-e414. Epub 2021 Jul 22 doi: 10.1016/j.jtcvs.2021.06.019. PMID: 34304896
Giant coronary sinus.
Nathani S, Parakh N, Chaturvedi V, Tyagi S
Tex Heart Inst J 2011;38(3):310-1. PMID: 21720482Free PMC Article
Aortico-right ventricular tunnel.
Vargas FJ, Molina A, Martinez JC, Ranzini ME, Vazquez JC
Ann Thorac Surg 1998 Nov;66(5):1793-5. doi: 10.1016/s0003-4975(98)00927-8. PMID: 9875792
Development and validation of an ECG algorithm for identifying accessory pathway ablation site in Wolff-Parkinson-White syndrome.
Arruda MS, McClelland JH, Wang X, Beckman KJ, Widman LE, Gonzalez MD, Nakagawa H, Lazzara R, Jackman WM
J Cardiovasc Electrophysiol 1998 Jan;9(1):2-12. doi: 10.1111/j.1540-8167.1998.tb00861.x. PMID: 9475572

Clinical prediction guides

Characterization of unipolar electrogram morphology: a novel tool for quantifying conduction inhomogeneity.
Ye Z, van Schie MS, Pool L, Heida A, Knops P, Taverne YJHJ, Brundel BJJM, de Groot NMS
Europace 2023 Nov 2;25(11) doi: 10.1093/europace/euad324. PMID: 37931071Free PMC Article
International consensus statement on nomenclature and classification of the congenital bicuspid aortic valve and its aortopathy, for clinical, surgical, interventional and research purposes.
Michelena HI, Della Corte A, Evangelista A, Maleszewski JJ, Edwards WD, Roman MJ, Devereux RB, Fernández B, Asch FM, Barker AJ, Sierra-Galan LM, De Kerchove L, Fernandes SM, Fedak PWM, Girdauskas E, Delgado V, Abbara S, Lansac E, Prakash SK, Bissell MM, Popescu BA, Hope MD, Sitges M, Thourani VH, Pibarot P, Chandrasekaran K, Lancellotti P, Borger MA, Forrest JK, Webb J, Milewicz DM, Makkar R, Leon MB, Sanders SP, Markl M, Ferrari VA, Roberts WC, Song JK, Blanke P, White CS, Siu S, Svensson LG, Braverman AC, Bavaria J, Sundt TM, El Khoury G, De Paulis R, Enriquez-Sarano M, Bax JJ, Otto CM, Schäfers HJ
J Thorac Cardiovasc Surg 2021 Sep;162(3):e383-e414. Epub 2021 Jul 22 doi: 10.1016/j.jtcvs.2021.06.019. PMID: 34304896
Anomalous Aortic Origin of a Coronary Artery Is Not Always a Surgical Disease.
Mosca RS, Phoon CK
Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 2016;19(1):30-6. doi: 10.1053/j.pcsu.2015.12.006. PMID: 27060040
Giant coronary sinus.
Nathani S, Parakh N, Chaturvedi V, Tyagi S
Tex Heart Inst J 2011;38(3):310-1. PMID: 21720482Free PMC Article
Development and validation of an ECG algorithm for identifying accessory pathway ablation site in Wolff-Parkinson-White syndrome.
Arruda MS, McClelland JH, Wang X, Beckman KJ, Widman LE, Gonzalez MD, Nakagawa H, Lazzara R, Jackman WM
J Cardiovasc Electrophysiol 1998 Jan;9(1):2-12. doi: 10.1111/j.1540-8167.1998.tb00861.x. PMID: 9475572

Recent systematic reviews

Surgical correction of anomalous origin of the right coronary artery from the left sinus of Valsalva: How, where, and when.
Belluschi I, Blasio A, Pozzoli A, Vicentini L, Alfieri O
Multimed Man Cardiothorac Surg 2019 Mar 5;2019 doi: 10.1510/mmcts.2019.005. PMID: 30990579

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