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Vesicoureteral reflux 4(VUR4)

MedGen UID:
482069
Concept ID:
C3280439
Disease or Syndrome
Synonym: VUR4
 
Monarch Initiative: MONDO:0013682
OMIM®: 614317

Professional guidelines

PubMed

Puri P, Granata C
J Urol 1998 Sep;160(3 Pt 2):1007-11; discussion 1038. doi: 10.1097/00005392-199809020-00011. PMID: 9719265

Recent clinical studies

Etiology

Hewitt I, Montini G
Pediatr Nephrol 2021 Apr;36(4):1011-1017. Epub 2020 Apr 22 doi: 10.1007/s00467-020-04573-9. PMID: 32323004
Bastos JM Netto, Rondon AV, Machado MG, Zerati M Filho, Nascimento RLP, Lima SVC, Calado AA, Barroso U Jr
Int Braz J Urol 2020 Jul-Aug;46(4):523-537. doi: 10.1590/S1677-5538.IBJU.2019.0401. PMID: 32167732Free PMC Article
Arlen AM, Cooper CS
Int J Urol 2019 Apr;26(4):440-445. Epub 2019 Feb 14 doi: 10.1111/iju.13915. PMID: 30762254
Bandari J, Docimo SG
J Pediatr Urol 2017 Aug;13(4):378-382. Epub 2017 May 22 doi: 10.1016/j.jpurol.2017.03.037. PMID: 28630017
Routh JC, Bogaert GA, Kaefer M, Manzoni G, Park JM, Retik AB, Rushton HG, Snodgrass WT, Wilcox DT
Eur Urol 2012 Apr;61(4):773-82. Epub 2012 Jan 11 doi: 10.1016/j.eururo.2012.01.002. PMID: 22264440

Diagnosis

Hari P, Meena J, Kumar M, Sinha A, Thergaonkar RW, Iyengar A, Khandelwal P, Ekambaram S, Pais P, Sharma J, Kanitkar M, Bagga A; Indian Society of Pediatric Nephrology
Pediatr Nephrol 2024 May;39(5):1639-1668. Epub 2023 Oct 28 doi: 10.1007/s00467-023-06173-9. PMID: 37897526
Herthelius M
Pediatr Nephrol 2023 Oct;38(10):3221-3227. Epub 2023 Mar 15 doi: 10.1007/s00467-023-05907-z. PMID: 36920569Free PMC Article
Hewitt I, Montini G
Pediatr Nephrol 2021 Apr;36(4):1011-1017. Epub 2020 Apr 22 doi: 10.1007/s00467-020-04573-9. PMID: 32323004
Routh JC, Bogaert GA, Kaefer M, Manzoni G, Park JM, Retik AB, Rushton HG, Snodgrass WT, Wilcox DT
Eur Urol 2012 Apr;61(4):773-82. Epub 2012 Jan 11 doi: 10.1016/j.eururo.2012.01.002. PMID: 22264440
Cendron M
J Pediatr Urol 2008 Dec;4(6):414-21. Epub 2008 Sep 4 doi: 10.1016/j.jpurol.2008.04.009. PMID: 18775677

Therapy

Morello W, Baskin E, Jankauskiene A, Yalcinkaya F, Zurowska A, Puccio G, Serafinelli J, La Manna A, Krzemień G, Pennesi M, La Scola C, Becherucci F, Brugnara M, Yuksel S, Mekahli D, Chimenz R, De Palma D, Zucchetta P, Vajauskas D, Drozdz D, Szczepanska M, Caliskan S, Lombet J, Minoli DG, Guarino S, Gulleroglu K, Ruzgiene D, Szmigielska A, Barbi E, Ozcakar ZB, Kranz A, Pasini A, Materassi M, De Rechter S, Ariceta G, Weber LT, Marzuillo P, Alberici I, Taranta-Janusz K, Caldas Afonso A, Tkaczyk M, Català M, Cabrera Sevilla JE, Mehls O, Schaefer F, Montini G; PREDICT Study Group
N Engl J Med 2023 Sep 14;389(11):987-997. Epub 2023 Sep 12 doi: 10.1056/NEJMoa2300161. PMID: 37702442
Herthelius M
Pediatr Nephrol 2023 Oct;38(10):3221-3227. Epub 2023 Mar 15 doi: 10.1007/s00467-023-05907-z. PMID: 36920569Free PMC Article
Hewitt I, Montini G
Pediatr Nephrol 2021 Apr;36(4):1011-1017. Epub 2020 Apr 22 doi: 10.1007/s00467-020-04573-9. PMID: 32323004
Williams G, Craig JC
Cochrane Database Syst Rev 2019 Apr 1;4(4):CD001534. doi: 10.1002/14651858.CD001534.pub4. PMID: 30932167Free PMC Article
Keren R, Shaikh N, Pohl H, Gravens-Mueller L, Ivanova A, Zaoutis L, Patel M, deBerardinis R, Parker A, Bhatnagar S, Haralam MA, Pope M, Kearney D, Sprague B, Barrera R, Viteri B, Egigueron M, Shah N, Hoberman A
Pediatrics 2015 Jul;136(1):e13-21. Epub 2015 Jun 8 doi: 10.1542/peds.2015-0409. PMID: 26055855Free PMC Article

Prognosis

Herthelius M
Pediatr Nephrol 2023 Oct;38(10):3221-3227. Epub 2023 Mar 15 doi: 10.1007/s00467-023-05907-z. PMID: 36920569Free PMC Article
Arlen AM, Cooper CS
Int J Urol 2019 Apr;26(4):440-445. Epub 2019 Feb 14 doi: 10.1111/iju.13915. PMID: 30762254
Keren R, Shaikh N, Pohl H, Gravens-Mueller L, Ivanova A, Zaoutis L, Patel M, deBerardinis R, Parker A, Bhatnagar S, Haralam MA, Pope M, Kearney D, Sprague B, Barrera R, Viteri B, Egigueron M, Shah N, Hoberman A
Pediatrics 2015 Jul;136(1):e13-21. Epub 2015 Jun 8 doi: 10.1542/peds.2015-0409. PMID: 26055855Free PMC Article
Batinic D, Miloševic D, Topalovic-Grkovic M, Nizic L, Vrljicak K, Batinic D, Turudic D
Urol Int 2013;90(4):480-3. Epub 2012 Dec 22 doi: 10.1159/000345713. PMID: 23295895
Routh JC, Bogaert GA, Kaefer M, Manzoni G, Park JM, Retik AB, Rushton HG, Snodgrass WT, Wilcox DT
Eur Urol 2012 Apr;61(4):773-82. Epub 2012 Jan 11 doi: 10.1016/j.eururo.2012.01.002. PMID: 22264440

Clinical prediction guides

Morello W, Baskin E, Jankauskiene A, Yalcinkaya F, Zurowska A, Puccio G, Serafinelli J, La Manna A, Krzemień G, Pennesi M, La Scola C, Becherucci F, Brugnara M, Yuksel S, Mekahli D, Chimenz R, De Palma D, Zucchetta P, Vajauskas D, Drozdz D, Szczepanska M, Caliskan S, Lombet J, Minoli DG, Guarino S, Gulleroglu K, Ruzgiene D, Szmigielska A, Barbi E, Ozcakar ZB, Kranz A, Pasini A, Materassi M, De Rechter S, Ariceta G, Weber LT, Marzuillo P, Alberici I, Taranta-Janusz K, Caldas Afonso A, Tkaczyk M, Català M, Cabrera Sevilla JE, Mehls O, Schaefer F, Montini G; PREDICT Study Group
N Engl J Med 2023 Sep 14;389(11):987-997. Epub 2023 Sep 12 doi: 10.1056/NEJMoa2300161. PMID: 37702442
Herthelius M
Pediatr Nephrol 2023 Oct;38(10):3221-3227. Epub 2023 Mar 15 doi: 10.1007/s00467-023-05907-z. PMID: 36920569Free PMC Article
Arlen AM, Cooper CS
Int J Urol 2019 Apr;26(4):440-445. Epub 2019 Feb 14 doi: 10.1111/iju.13915. PMID: 30762254
Keren R, Shaikh N, Pohl H, Gravens-Mueller L, Ivanova A, Zaoutis L, Patel M, deBerardinis R, Parker A, Bhatnagar S, Haralam MA, Pope M, Kearney D, Sprague B, Barrera R, Viteri B, Egigueron M, Shah N, Hoberman A
Pediatrics 2015 Jul;136(1):e13-21. Epub 2015 Jun 8 doi: 10.1542/peds.2015-0409. PMID: 26055855Free PMC Article
Routh JC, Bogaert GA, Kaefer M, Manzoni G, Park JM, Retik AB, Rushton HG, Snodgrass WT, Wilcox DT
Eur Urol 2012 Apr;61(4):773-82. Epub 2012 Jan 11 doi: 10.1016/j.eururo.2012.01.002. PMID: 22264440

Recent systematic reviews

Basiri A, Ziaeefar P, Khoshdel A, Fattahi P, Mafi Balani M, Tofighi Zavareh MA
Urol J 2023 Dec 26;20(6):385-396. doi: 10.22037/uj.v20i06.8095. PMID: 38158632
Yang S, Gill PJ, Anwar MR, Nurse K, Mahood Q, Borkhoff CM, Bijelic V, Parkin PC, Mahant S; Canadian Paediatric Inpatient Research Network (PIRN)
JAMA Pediatr 2023 Aug 1;177(8):764-773. doi: 10.1001/jamapediatrics.2023.1387. PMID: 37252727Free PMC Article
Williams G, Craig JC
Cochrane Database Syst Rev 2019 Apr 1;4(4):CD001534. doi: 10.1002/14651858.CD001534.pub4. PMID: 30932167Free PMC Article
Yap TL, Chen Y, Nah SA, Ong CC, Jacobsen A, Low Y
J Pediatr Surg 2016 Dec;51(12):2015-2020. Epub 2016 Sep 16 doi: 10.1016/j.jpedsurg.2016.09.028. PMID: 27773360
Routh JC, Bogaert GA, Kaefer M, Manzoni G, Park JM, Retik AB, Rushton HG, Snodgrass WT, Wilcox DT
Eur Urol 2012 Apr;61(4):773-82. Epub 2012 Jan 11 doi: 10.1016/j.eururo.2012.01.002. PMID: 22264440

Supplemental Content

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