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Giant Cell Angioblastoma

MedGen UID:
474859
•Concept ID:
C3273226
•
Neoplastic Process

Definition

A rare, slow-growing, locally aggressive soft tissue tumor characterized by the presence of oval to spindle cells forming concentric aggregates around small vessels. Giant multinucleated cells are also present. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGiant Cell Angioblastoma

Recent clinical studies

Diagnosis

Giant cell angioblastoma of bone: four new cases provide further evidence of its distinct clinical and histopathological characteristics.
Yu L, Lao IW, Wang J
Virchows Arch 2015 Jul;467(1):95-103. Epub 2015 Mar 28 doi: 10.1007/s00428-015-1757-0. PMID: 25820372
Clinical and pathological characteristics of giant cell angioblastoma: a case report.
Mao RJ, Jiang ZM, Zhang HZ, Zhu XZ, Zhang QL
Diagn Pathol 2012 Aug 29;7:113. doi: 10.1186/1746-1596-7-113. PMID: 22929620Free PMC Article
Cutaneous vascular tumours: an update.
Goh SG, Calonje E
Histopathology 2008 May;52(6):661-73. Epub 2008 Feb 6 doi: 10.1111/j.1365-2559.2007.02924.x. PMID: 18266723
MRI in an unusual case of congenital spinal mesenchymal proliferation.
Tortori-Donati P, Fondelli MP, Rossi A, Andreussi L, Brisigotti M, Garrè ML
Neuroradiology 1996 May;38 Suppl 1:S196-9. doi: 10.1007/BF02278159. PMID: 8811715
Recently characterized vascular tumours of skin and soft tissues.
Tsang WY, Chan JK, Fletcher CD
Histopathology 1991 Dec;19(6):489-501. doi: 10.1111/j.1365-2559.1991.tb01497.x. PMID: 1786935

Therapy

Successful antiangiogenic therapy of giant cell angioblastoma with interferon alfa 2b: report of 2 cases.
Marler JJ, Rubin JB, Trede NS, Connors S, Grier H, Upton J, Mulliken JB, Folkman J
Pediatrics 2002 Feb;109(2):E37. doi: 10.1542/peds.109.2.e37. PMID: 11826247

Prognosis

Clinical and pathological characteristics of giant cell angioblastoma: a case report.
Mao RJ, Jiang ZM, Zhang HZ, Zhu XZ, Zhang QL
Diagn Pathol 2012 Aug 29;7:113. doi: 10.1186/1746-1596-7-113. PMID: 22929620Free PMC Article

Clinical prediction guides

Clinical and pathological characteristics of giant cell angioblastoma: a case report.
Mao RJ, Jiang ZM, Zhang HZ, Zhu XZ, Zhang QL
Diagn Pathol 2012 Aug 29;7:113. doi: 10.1186/1746-1596-7-113. PMID: 22929620Free PMC Article
Intravenous tufted angioma.
Fukunaga M
APMIS 2000 Apr;108(4):287-92. doi: 10.1034/j.1600-0463.2000.d01-58.x. PMID: 10843417

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