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Small intestinal diffuse large B-cell lymphoma

MedGen UID:
474155
•Concept ID:
C3272522
•
Neoplastic Process
Synonyms: diffuse large B-cell lymphoma of small intestine; Primary Small Intestinal Diffuse Large B-Cell Lymphoma; Primary Small Intestinal DLBCL; Small Intestinal Diffuse Large B-Cell Lymphoma; small intestinal diffuse large B-cell lymphoma; Small Intestinal DLBCL; small intestine diffuse large B-cell lymphoma
 
Monarch Initiative: MONDO:0006417

Definition

A diffuse large B-cell lymphoma that arises from the small intestine. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSmall intestinal diffuse large B-cell lymphoma

Professional guidelines

PubMed

Review of lymphoma in the duodenum: An update of diagnosis and management.
Iwamuro M, Tanaka T, Okada H
World J Gastroenterol 2023 Mar 28;29(12):1852-1862. doi: 10.3748/wjg.v29.i12.1852. PMID: 37032723Free PMC Article
Gastrointestinal lymphoma: recent advances in diagnosis and treatment.
Nakamura S, Matsumoto T
Digestion 2013;87(3):182-8. Epub 2013 Apr 27 doi: 10.1159/000350051. PMID: 23635497
Role of radiotherapy in the treatment of lymphomas of the gastrointestinal tract.
Aleman BM, Haas RL, van der Maazen RW
Best Pract Res Clin Gastroenterol 2010 Feb;24(1):27-34. doi: 10.1016/j.bpg.2009.12.002. PMID: 20206106

Recent clinical studies

Etiology

B Cell Lymphomas of the GI Tract.
Small S, Barnea Slonim L, Williams C, Karmali R
Curr Gastroenterol Rep 2021 May 8;23(7):9. doi: 10.1007/s11894-021-00811-8. PMID: 33963950
New developments in non-Hodgkin lymphoid malignancies.
Ganapathi KA, Brown LE, Prakash S, Bhargava P
Pathology 2021 Apr;53(3):349-366. Epub 2021 Mar 5 doi: 10.1016/j.pathol.2021.01.002. PMID: 33685720
Gastrointestinal non-Hodgkin lymphomas.
Olszewska-Szopa M, Wróbel T
Adv Clin Exp Med 2019 Aug;28(8):1119-1124. doi: 10.17219/acem/94068. PMID: 31414733
Primary Gastrointestinal Non-Hodgkin's Lymphoma of the Small and Large Intestines: a Systematic Review.
Lightner AL, Shannon E, Gibbons MM, Russell MM
J Gastrointest Surg 2016 Apr;20(4):827-39. Epub 2015 Dec 16 doi: 10.1007/s11605-015-3052-4. PMID: 26676930
Chronic anemia masking a primary large B-cell lymphoma of the small intestine, finally diagnosed by double-balloon enteroscopy.
Weigand K, Ganten TM, Andrulis M, Stremmel W, Sauer P, Schaible A
Endoscopy 2008 Sep;40 Suppl 2:E149. Epub 2008 Jul 16 doi: 10.1055/s-2007-995772. PMID: 18633862

Diagnosis

Review of lymphoma in the duodenum: An update of diagnosis and management.
Iwamuro M, Tanaka T, Okada H
World J Gastroenterol 2023 Mar 28;29(12):1852-1862. doi: 10.3748/wjg.v29.i12.1852. PMID: 37032723Free PMC Article
Gastrointestinal non-Hodgkin lymphomas.
Olszewska-Szopa M, Wróbel T
Adv Clin Exp Med 2019 Aug;28(8):1119-1124. doi: 10.17219/acem/94068. PMID: 31414733
Intravascular large B cell lymphoma diagnosed in random duodenal biopsies. A case report and a literature review.
Linnik Y, Rand J, Kaur P, Liu X
Virchows Arch 2017 Sep;471(3):429-431. Epub 2017 May 4 doi: 10.1007/s00428-017-2136-9. PMID: 28474092
Diffuse large B-cell lymphoma of the small bowel as an unusual cause for recurrent obscure gastrointestinal bleeding: diagnosis by video capsule endoscopy.
Meister T, Schaefer IM, Domschke W
Clin Gastroenterol Hepatol 2012 Nov;10(11):e89-90. Epub 2012 Jul 17 doi: 10.1016/j.cgh.2012.06.033. PMID: 22813442
Primary gastrointestinal lymphoma.
Ghimire P, Wu GY, Zhu L
World J Gastroenterol 2011 Feb 14;17(6):697-707. doi: 10.3748/wjg.v17.i6.697. PMID: 21390139Free PMC Article

Therapy

Extensive small intestinal diffuse large B cell lymphoma.
Liu X, Lv T, Zhang X, Li J
Rev Esp Enferm Dig 2023 May;115(5):267. doi: 10.17235/reed.2022.9100/2022. PMID: 36043558
A Rare Case of Ileocecal Valve Stricture.
Tan IJ, Tan KK
Gastroenterology 2020 Nov;159(5):e14-e15. Epub 2020 Apr 18 doi: 10.1053/j.gastro.2020.04.024. PMID: 32311365
Intravascular large B cell lymphoma diagnosed in random duodenal biopsies. A case report and a literature review.
Linnik Y, Rand J, Kaur P, Liu X
Virchows Arch 2017 Sep;471(3):429-431. Epub 2017 May 4 doi: 10.1007/s00428-017-2136-9. PMID: 28474092
Bortezomib-contained chemotherapy and thalidomide combined with CHOP (Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone) play promising roles in plasmablastic lymphoma: a case report and literature review.
Cao C, Liu T, Zhu H, Wang L, Kai S, Xiang B
Clin Lymphoma Myeloma Leuk 2014 Oct;14(5):e145-50. Epub 2014 Jun 11 doi: 10.1016/j.clml.2014.03.002. PMID: 25225082
Primary gastrointestinal lymphoma.
Ghimire P, Wu GY, Zhu L
World J Gastroenterol 2011 Feb 14;17(6):697-707. doi: 10.3748/wjg.v17.i6.697. PMID: 21390139Free PMC Article

Prognosis

Primary Gastrointestinal Non-Hodgkin's Lymphoma of the Small and Large Intestines: a Systematic Review.
Lightner AL, Shannon E, Gibbons MM, Russell MM
J Gastrointest Surg 2016 Apr;20(4):827-39. Epub 2015 Dec 16 doi: 10.1007/s11605-015-3052-4. PMID: 26676930
Bortezomib-contained chemotherapy and thalidomide combined with CHOP (Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone) play promising roles in plasmablastic lymphoma: a case report and literature review.
Cao C, Liu T, Zhu H, Wang L, Kai S, Xiang B
Clin Lymphoma Myeloma Leuk 2014 Oct;14(5):e145-50. Epub 2014 Jun 11 doi: 10.1016/j.clml.2014.03.002. PMID: 25225082
Primary gastrointestinal lymphoma.
Ghimire P, Wu GY, Zhu L
World J Gastroenterol 2011 Feb 14;17(6):697-707. doi: 10.3748/wjg.v17.i6.697. PMID: 21390139Free PMC Article
Chronic anemia masking a primary large B-cell lymphoma of the small intestine, finally diagnosed by double-balloon enteroscopy.
Weigand K, Ganten TM, Andrulis M, Stremmel W, Sauer P, Schaible A
Endoscopy 2008 Sep;40 Suppl 2:E149. Epub 2008 Jul 16 doi: 10.1055/s-2007-995772. PMID: 18633862
Pathology of intestinal lymphomas.
Foss HD, Stein H
Recent Results Cancer Res 2000;156:33-41. doi: 10.1007/978-3-642-57054-4_5. PMID: 10802861

Clinical prediction guides

Pathogenesis of Gastrointestinal Follicular Lymphomas: Consideration Based on Histopathology and Endoscopic Findings.
Takahashi Y, Taniguchi H, Haruhi F, Hattori D, Sasaki H, Makita S, Iwaki N, Fukuhara S, Munakata W, Saito Y, Izutsu K, Maeshima AM
Am J Surg Pathol 2023 Oct 1;47(10):1134-1143. Epub 2023 Jul 27 doi: 10.1097/PAS.0000000000002095. PMID: 37493666
Diffuse large B cell lymphoma CD5-positive arising in an immune deficiency and immune dysregulation setting: A case report and brief review of the literature.
Cristian M, Baz RA, Stoica AG, Așchie M, Ghinea MM, Deacu M, Boșoteanu M, Mitroi AF, Dobrin N, Iordache IE, Bălțătescu GI
Medicine (Baltimore) 2023 Feb 22;102(8):e33083. doi: 10.1097/MD.0000000000033083. PMID: 36827036Free PMC Article
Prognostic value of chromosomal translocations in small-bowel diffuse large B-cell lymphoma.
Ikegami K, Nakamura S, Esaki M, Yanai S, Hirahashi M, Oda Y, Takeshita M, Matsumoto T, Kitazono T
Histopathology 2016 Jan;68(2):199-209. Epub 2015 Jun 18 doi: 10.1111/his.12731. PMID: 25953462
Endoscopic ultrasound-guided fine-needle aspiration for duodenal obstruction without a discrete mass.
Nakai Y, Isayama H, Takahara N, Hamada T, Mohri D, Kogure H, Matsubara S, Yamamoto N, Tada M, Koike K
Dig Dis Sci 2015 May;60(5):1502-4. Epub 2014 Nov 28 doi: 10.1007/s10620-014-3458-y. PMID: 25431045
Pathology of intestinal lymphomas.
Foss HD, Stein H
Recent Results Cancer Res 2000;156:33-41. doi: 10.1007/978-3-642-57054-4_5. PMID: 10802861

Recent systematic reviews

Emergency laparotomy for abdominal catastrophes secondary to lymphoma: A systematic review.
Butterworth JW, Brooker-Thompson C, Qureshi YA, Mohammadi B, Dawas K
Eur J Surg Oncol 2024 Jan;50(1):107268. Epub 2023 Nov 19 doi: 10.1016/j.ejso.2023.107268. PMID: 38043361
Primary Gastrointestinal Non-Hodgkin's Lymphoma of the Small and Large Intestines: a Systematic Review.
Lightner AL, Shannon E, Gibbons MM, Russell MM
J Gastrointest Surg 2016 Apr;20(4):827-39. Epub 2015 Dec 16 doi: 10.1007/s11605-015-3052-4. PMID: 26676930
Composite EBV negative peripheral T-cell lymphoma and diffuse large B-cell lymphoma involving the ileum: a case report and a systematic review of the literature.
Abou-Elella AA, Nifong TP
Leuk Lymphoma 2006 Oct;47(10):2208-17. doi: 10.1080/10428190600763348. PMID: 17071497

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