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Panic disorder with agoraphobia

MedGen UID:
472969
•Concept ID:
C0236800
•
Mental or Behavioral Dysfunction
Synonyms: Panic Disorder with Agoraphobia; panic disorder with agoraphobia
SNOMED CT: Panic disorder with agoraphobia (35607004)
 
Monarch Initiative: MONDO:0044144

Definition

A disorder in which an individual experiences recurrent, unexpected panic attacks and persistent concern about having additional panic attacks. Agoraphobia is a component of this disorder. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPanic disorder with agoraphobia

Professional guidelines

PubMed

Diagnosis and treatment of agoraphobia with panic disorder.
Perugi G, Frare F, Toni C
CNS Drugs 2007;21(9):741-64. doi: 10.2165/00023210-200721090-00004. PMID: 17696574
Algorithm for the treatment of panic disorder with agoraphobia.
Jobson KO, Davidson JR, Lydiard RB, McCann UD, Pollack MH, Rosenbaum JF
Psychopharmacol Bull 1995;31(3):483-5. PMID: 8668753
Effectiveness of a meditation-based stress reduction program in the treatment of anxiety disorders.
Kabat-Zinn J, Massion AO, Kristeller J, Peterson LG, Fletcher KE, Pbert L, Lenderking WR, Santorelli SF
Am J Psychiatry 1992 Jul;149(7):936-43. doi: 10.1176/ajp.149.7.936. PMID: 1609875

Curated

UK NICE Clinical Guideline CG113, Generalised anxiety disorder and panic disorder in adults: management

Recent clinical studies

Etiology

Bipolar disorder comorbidity in patients with obsessive-compulsive disorder: Prevalence and predictors.
Domingues-Castro MS, Torresan RC, Shavitt RG, Fontenelle LF, Ferrão YA, Rosário MC, Torres AR
J Affect Disord 2019 Sep 1;256:324-330. Epub 2019 Jun 7 doi: 10.1016/j.jad.2019.06.018. PMID: 31201983
Panic disorder with agoraphobia from a behavioral neuroscience perspective: Applying the research principles formulated by the Research Domain Criteria (RDoC) initiative.
Hamm AO, Richter J, Pané-Farré C, Westphal D, Wittchen HU, Vossbeck-Elsebusch AN, Gerlach AL, Gloster AT, Ströhle A, Lang T, Kircher T, Gerdes AB, Alpers GW, Reif A, Deckert J
Psychophysiology 2016 Mar;53(3):312-22. doi: 10.1111/psyp.12553. PMID: 26877119
Personality disorders and anxiety disorders: what is the relationship?
Latas M, Milovanovic S
Curr Opin Psychiatry 2014 Jan;27(1):57-61. doi: 10.1097/YCO.0000000000000025. PMID: 24270478
Long-term stability of cognitive behavioral therapy effects for panic disorder with agoraphobia: a two-year follow-up study.
Gloster AT, Hauke C, Höfler M, Einsle F, Fydrich T, Hamm A, Sthröhle A, Wittchen HU
Behav Res Ther 2013 Dec;51(12):830-9. Epub 2013 Oct 9 doi: 10.1016/j.brat.2013.09.009. PMID: 24184430
Effectiveness of a meditation-based stress reduction program in the treatment of anxiety disorders.
Kabat-Zinn J, Massion AO, Kristeller J, Peterson LG, Fletcher KE, Pbert L, Lenderking WR, Santorelli SF
Am J Psychiatry 1992 Jul;149(7):936-43. doi: 10.1176/ajp.149.7.936. PMID: 1609875

Diagnosis

Impulsivity across psychiatric disorders in young adults.
Crisp ZC, Grant JE
Compr Psychiatry 2024 Apr;130:152449. Epub 2024 Jan 4 doi: 10.1016/j.comppsych.2023.152449. PMID: 38184857
Panic attack provocation in panic disorder patients with a computer simulation.
Freire RC, Ferreira-Garcia R, Cabo MC, Martins RM, Nardi AE
J Affect Disord 2020 Mar 1;264:498-505. Epub 2019 Nov 13 doi: 10.1016/j.jad.2019.11.081. PMID: 31786029
Long-term benzodiazepine use is associated with smaller treatment gain in panic disorder with agoraphobia.
van Balkom AJ, de Beurs E, Koele P, Lange A, van Dyck R
J Nerv Ment Dis 1996 Feb;184(2):133-5. doi: 10.1097/00005053-199602000-00015. PMID: 8596113
Porphyria and panic disorder with agoraphobia.
Vgontzas AN, Kales JD, Ballard JO, Vela-Bueno A, Tan TL
Psychosomatics 1993 Sep-Oct;34(5):440-3. doi: 10.1016/S0033-3182(93)71848-4. PMID: 8140193
Effectiveness of a meditation-based stress reduction program in the treatment of anxiety disorders.
Kabat-Zinn J, Massion AO, Kristeller J, Peterson LG, Fletcher KE, Pbert L, Lenderking WR, Santorelli SF
Am J Psychiatry 1992 Jul;149(7):936-43. doi: 10.1176/ajp.149.7.936. PMID: 1609875

Therapy

Long-term stability of cognitive behavioral therapy effects for panic disorder with agoraphobia: a two-year follow-up study.
Gloster AT, Hauke C, Höfler M, Einsle F, Fydrich T, Hamm A, Sthröhle A, Wittchen HU
Behav Res Ther 2013 Dec;51(12):830-9. Epub 2013 Oct 9 doi: 10.1016/j.brat.2013.09.009. PMID: 24184430
Long-term benzodiazepine use is associated with smaller treatment gain in panic disorder with agoraphobia.
van Balkom AJ, de Beurs E, Koele P, Lange A, van Dyck R
J Nerv Ment Dis 1996 Feb;184(2):133-5. doi: 10.1097/00005053-199602000-00015. PMID: 8596113
Porphyria and panic disorder with agoraphobia.
Vgontzas AN, Kales JD, Ballard JO, Vela-Bueno A, Tan TL
Psychosomatics 1993 Sep-Oct;34(5):440-3. doi: 10.1016/S0033-3182(93)71848-4. PMID: 8140193
Vestibular dysfunction followed by panic disorder with agoraphobia.
Lilienfeld SO, Jacob RG, Furman JM
J Nerv Ment Dis 1989 Nov;177(11):700-1. doi: 10.1097/00005053-198911000-00009. PMID: 2809581
Differential effects of imipramine and behavior therapy on panic disorder with agoraphobia.
Mavissakalian M
Psychopharmacol Bull 1989;25(1):27-9. PMID: 2672069

Prognosis

Panic attack provocation in panic disorder patients with a computer simulation.
Freire RC, Ferreira-Garcia R, Cabo MC, Martins RM, Nardi AE
J Affect Disord 2020 Mar 1;264:498-505. Epub 2019 Nov 13 doi: 10.1016/j.jad.2019.11.081. PMID: 31786029
Bipolar disorder comorbidity in patients with obsessive-compulsive disorder: Prevalence and predictors.
Domingues-Castro MS, Torresan RC, Shavitt RG, Fontenelle LF, Ferrão YA, Rosário MC, Torres AR
J Affect Disord 2019 Sep 1;256:324-330. Epub 2019 Jun 7 doi: 10.1016/j.jad.2019.06.018. PMID: 31201983
Long-term stability of cognitive behavioral therapy effects for panic disorder with agoraphobia: a two-year follow-up study.
Gloster AT, Hauke C, Höfler M, Einsle F, Fydrich T, Hamm A, Sthröhle A, Wittchen HU
Behav Res Ther 2013 Dec;51(12):830-9. Epub 2013 Oct 9 doi: 10.1016/j.brat.2013.09.009. PMID: 24184430
Effectiveness of a meditation-based stress reduction program in the treatment of anxiety disorders.
Kabat-Zinn J, Massion AO, Kristeller J, Peterson LG, Fletcher KE, Pbert L, Lenderking WR, Santorelli SF
Am J Psychiatry 1992 Jul;149(7):936-43. doi: 10.1176/ajp.149.7.936. PMID: 1609875
Panic disorder with agoraphobia.
Mathis JL
N C Med J 1988 Oct;49(10):521-2. PMID: 3185753

Clinical prediction guides

Impulsivity across psychiatric disorders in young adults.
Crisp ZC, Grant JE
Compr Psychiatry 2024 Apr;130:152449. Epub 2024 Jan 4 doi: 10.1016/j.comppsych.2023.152449. PMID: 38184857
Panic attack provocation in panic disorder patients with a computer simulation.
Freire RC, Ferreira-Garcia R, Cabo MC, Martins RM, Nardi AE
J Affect Disord 2020 Mar 1;264:498-505. Epub 2019 Nov 13 doi: 10.1016/j.jad.2019.11.081. PMID: 31786029
Bipolar disorder comorbidity in patients with obsessive-compulsive disorder: Prevalence and predictors.
Domingues-Castro MS, Torresan RC, Shavitt RG, Fontenelle LF, Ferrão YA, Rosário MC, Torres AR
J Affect Disord 2019 Sep 1;256:324-330. Epub 2019 Jun 7 doi: 10.1016/j.jad.2019.06.018. PMID: 31201983
Long-term stability of cognitive behavioral therapy effects for panic disorder with agoraphobia: a two-year follow-up study.
Gloster AT, Hauke C, Höfler M, Einsle F, Fydrich T, Hamm A, Sthröhle A, Wittchen HU
Behav Res Ther 2013 Dec;51(12):830-9. Epub 2013 Oct 9 doi: 10.1016/j.brat.2013.09.009. PMID: 24184430
Effectiveness of a meditation-based stress reduction program in the treatment of anxiety disorders.
Kabat-Zinn J, Massion AO, Kristeller J, Peterson LG, Fletcher KE, Pbert L, Lenderking WR, Santorelli SF
Am J Psychiatry 1992 Jul;149(7):936-43. doi: 10.1176/ajp.149.7.936. PMID: 1609875

Recent systematic reviews

Combination of psychotherapy and benzodiazepines versus either therapy alone for panic disorder: a systematic review.
Watanabe N, Churchill R, Furukawa TA
BMC Psychiatry 2007 May 14;7:18. doi: 10.1186/1471-244X-7-18. PMID: 17501985Free PMC Article

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    Curated

    • NICE, 2020
      UK NICE Clinical Guideline CG113, Generalised anxiety disorder and panic disorder in adults: management

    Consumer resources

    Reviews

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      Related information in PubMed Central Links
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