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Acute tonsillitis

MedGen UID:
472878
•Concept ID:
C0001361
•
Disease or Syndrome
Synonym: Acute adenoiditis
SNOMED CT: Acute tonsillitis (17741008); Infective tonsillitis (17741008)
 
Monarch Initiative: MONDO:0020686

Definition

An acute inflammation of the tonsils caused by viruses or bacteria. Signs and symptoms include fever, enlargement of the tonsils, difficulty swallowing, and enlargement of the regional lymph nodes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAcute tonsillitis

Professional guidelines

PubMed

Complementary and alternative medicine in the (symptomatic) treatment of acute tonsillitis in children: A systematic review.
Büttner R, Schwermer M, Ostermann T, Längler A, Zuzak T
Complement Ther Med 2023 May;73:102940. Epub 2023 Mar 1 doi: 10.1016/j.ctim.2023.102940. PMID: 36868289
Corticosteroids for treatment of sore throat: systematic review and meta-analysis of randomised trials.
Sadeghirad B, Siemieniuk RAC, Brignardello-Petersen R, Papola D, Lytvyn L, Vandvik PO, Merglen A, Guyatt GH, Agoritsas T
BMJ 2017 Sep 20;358:j3887. doi: 10.1136/bmj.j3887. PMID: 28931508Free PMC Article
Clinical practice guideline: tonsillitis I. Diagnostics and nonsurgical management.
Windfuhr JP, Toepfner N, Steffen G, Waldfahrer F, Berner R
Eur Arch Otorhinolaryngol 2016 Apr;273(4):973-87. Epub 2016 Jan 11 doi: 10.1007/s00405-015-3872-6. PMID: 26755048Free PMC Article

Recent clinical studies

Etiology

The impact of social restrictions on the incidence and microbiology of severe acute tonsillitis.
Sørensen TL, Greve T, Klug TE
Dan Med J 2024 Sep 10;71(10) doi: 10.61409/A03240161. PMID: 39323261
Conservative management versus tonsillectomy in adults with recurrent acute tonsillitis in the UK (NATTINA): a multicentre, open-label, randomised controlled trial.
Wilson JA, O'Hara J, Fouweather T, Homer T, Stocken DD, Vale L, Haighton C, Rousseau N, Wilson R, McSweeney L, Wilkes S, Morrison J, MacKenzie K, Ah-See K, Carrie S, Hopkins C, Howe N, Hussain M, Mehanna H, Raine C, Sullivan F, von Wilamowitz-Moellendorff A, Teare MD
Lancet 2023 Jun 17;401(10393):2051-2059. Epub 2023 May 17 doi: 10.1016/S0140-6736(23)00519-6. PMID: 37209706
Corticosteroids for treatment of sore throat: systematic review and meta-analysis of randomised trials.
Sadeghirad B, Siemieniuk RAC, Brignardello-Petersen R, Papola D, Lytvyn L, Vandvik PO, Merglen A, Guyatt GH, Agoritsas T
BMJ 2017 Sep 20;358:j3887. doi: 10.1136/bmj.j3887. PMID: 28931508Free PMC Article
Peritonsillar abscess: clinical aspects of microbiology, risk factors, and the association with parapharyngeal abscess.
Klug TE
Dan Med J 2017 Mar;64(3) PMID: 28260599
Efficacy and safety of 'hot' tonsillectomy.
Maheshwar AA, Jones MB, Evans RA
Int J Clin Pract 2001 Mar;55(2):93-5. PMID: 11321867

Diagnosis

Acute Tonsillitis Due To Monkeypox.
Studemeister L, Pai S, Walsh K, Cooper J
J Emerg Med 2023 Feb;64(2):211-213. Epub 2023 Feb 22 doi: 10.1016/j.jemermed.2022.12.029. PMID: 36822985Free PMC Article
Peritonsillar abscess: clinical aspects of microbiology, risk factors, and the association with parapharyngeal abscess.
Klug TE
Dan Med J 2017 Mar;64(3) PMID: 28260599
Clinical practice guideline: tonsillitis I. Diagnostics and nonsurgical management.
Windfuhr JP, Toepfner N, Steffen G, Waldfahrer F, Berner R
Eur Arch Otorhinolaryngol 2016 Apr;273(4):973-87. Epub 2016 Jan 11 doi: 10.1007/s00405-015-3872-6. PMID: 26755048Free PMC Article
Tonsillitis.
Georgalas CC, Tolley NS, Narula PA
BMJ Clin Evid 2014 Jul 22;2014 PMID: 25051184Free PMC Article
Acute tonsillitis.
Sidell D, Shapiro NL
Infect Disord Drug Targets 2012 Aug;12(4):271-6. doi: 10.2174/187152612801319230. PMID: 22338587

Therapy

Conservative management versus tonsillectomy in adults with recurrent acute tonsillitis in the UK (NATTINA): a multicentre, open-label, randomised controlled trial.
Wilson JA, O'Hara J, Fouweather T, Homer T, Stocken DD, Vale L, Haighton C, Rousseau N, Wilson R, McSweeney L, Wilkes S, Morrison J, MacKenzie K, Ah-See K, Carrie S, Hopkins C, Howe N, Hussain M, Mehanna H, Raine C, Sullivan F, von Wilamowitz-Moellendorff A, Teare MD
Lancet 2023 Jun 17;401(10393):2051-2059. Epub 2023 May 17 doi: 10.1016/S0140-6736(23)00519-6. PMID: 37209706
Corticosteroids for treatment of sore throat: systematic review and meta-analysis of randomised trials.
Sadeghirad B, Siemieniuk RAC, Brignardello-Petersen R, Papola D, Lytvyn L, Vandvik PO, Merglen A, Guyatt GH, Agoritsas T
BMJ 2017 Sep 20;358:j3887. doi: 10.1136/bmj.j3887. PMID: 28931508Free PMC Article
Peritonsillar abscess: clinical aspects of microbiology, risk factors, and the association with parapharyngeal abscess.
Klug TE
Dan Med J 2017 Mar;64(3) PMID: 28260599
Clinical practice guideline: tonsillitis I. Diagnostics and nonsurgical management.
Windfuhr JP, Toepfner N, Steffen G, Waldfahrer F, Berner R
Eur Arch Otorhinolaryngol 2016 Apr;273(4):973-87. Epub 2016 Jan 11 doi: 10.1007/s00405-015-3872-6. PMID: 26755048Free PMC Article
Ceftriaxone-induced toxic hepatitis.
Peker E, Cagan E, Dogan M
World J Gastroenterol 2009 Jun 7;15(21):2669-71. doi: 10.3748/wjg.15.2669. PMID: 19496200Free PMC Article

Prognosis

The impact of social restrictions on the incidence and microbiology of severe acute tonsillitis.
Sørensen TL, Greve T, Klug TE
Dan Med J 2024 Sep 10;71(10) doi: 10.61409/A03240161. PMID: 39323261
Ubi pus, ibi evacua: a review of 601 peritonsillar abscess adult cases.
Sideris G, Malamas V, Tyrellis G, Maragkoudakis P, Delides A, Nikolopoulos T
Ir J Med Sci 2022 Aug;191(4):1849-1853. Epub 2021 Oct 6 doi: 10.1007/s11845-021-02796-9. PMID: 34617243Free PMC Article
Peritonsillar abscess: clinical aspects of microbiology, risk factors, and the association with parapharyngeal abscess.
Klug TE
Dan Med J 2017 Mar;64(3) PMID: 28260599
Isolated idiopathic unilateral paralysis of soft palate and pharynx.
Sondhi V, Patnaik SK
Indian Pediatr 2011 Mar;48(3):237-9. PMID: 21478558
Effect of acute tonsillitis and tonsillectomy on the course of nephritis.
LUMIO JS
Acta Otolaryngol 1952;42(1-2):113-24. doi: 10.3109/00016485209120334. PMID: 14932972

Clinical prediction guides

The impact of social restrictions on the incidence and microbiology of severe acute tonsillitis.
Sørensen TL, Greve T, Klug TE
Dan Med J 2024 Sep 10;71(10) doi: 10.61409/A03240161. PMID: 39323261
Conservative management versus tonsillectomy in adults with recurrent acute tonsillitis in the UK (NATTINA): a multicentre, open-label, randomised controlled trial.
Wilson JA, O'Hara J, Fouweather T, Homer T, Stocken DD, Vale L, Haighton C, Rousseau N, Wilson R, McSweeney L, Wilkes S, Morrison J, MacKenzie K, Ah-See K, Carrie S, Hopkins C, Howe N, Hussain M, Mehanna H, Raine C, Sullivan F, von Wilamowitz-Moellendorff A, Teare MD
Lancet 2023 Jun 17;401(10393):2051-2059. Epub 2023 May 17 doi: 10.1016/S0140-6736(23)00519-6. PMID: 37209706
Peritonsillar abscess: clinical aspects of microbiology, risk factors, and the association with parapharyngeal abscess.
Klug TE
Dan Med J 2017 Mar;64(3) PMID: 28260599
Clinical practice guideline: tonsillitis I. Diagnostics and nonsurgical management.
Windfuhr JP, Toepfner N, Steffen G, Waldfahrer F, Berner R
Eur Arch Otorhinolaryngol 2016 Apr;273(4):973-87. Epub 2016 Jan 11 doi: 10.1007/s00405-015-3872-6. PMID: 26755048Free PMC Article
Tonsillitis.
Georgalas CC, Tolley NS, Narula A
BMJ Clin Evid 2009 Oct 26;2009 PMID: 21718574Free PMC Article

Recent systematic reviews

Complementary and alternative medicine in the (symptomatic) treatment of acute tonsillitis in children: A systematic review.
Büttner R, Schwermer M, Ostermann T, Längler A, Zuzak T
Complement Ther Med 2023 May;73:102940. Epub 2023 Mar 1 doi: 10.1016/j.ctim.2023.102940. PMID: 36868289
Immediate or interval abscess tonsillectomy? A systematic review and meta-analysis.
Tsikopoulos A, Fountarlis A, Tsikopoulos K, Dilmperis F, Garefis K, Tsikopoulos I, Skoulakis C, Karkos P, Triaridis S
Eur Arch Otorhinolaryngol 2022 May;279(5):2245-2257. Epub 2022 Feb 15 doi: 10.1007/s00405-022-07294-x. PMID: 35169892
Corticosteroids for treatment of sore throat: systematic review and meta-analysis of randomised trials.
Sadeghirad B, Siemieniuk RAC, Brignardello-Petersen R, Papola D, Lytvyn L, Vandvik PO, Merglen A, Guyatt GH, Agoritsas T
BMJ 2017 Sep 20;358:j3887. doi: 10.1136/bmj.j3887. PMID: 28931508Free PMC Article
Tonsillitis.
Georgalas CC, Tolley NS, Narula PA
BMJ Clin Evid 2014 Jul 22;2014 PMID: 25051184Free PMC Article
Tonsillitis.
Georgalas CC, Tolley NS, Narula A
BMJ Clin Evid 2009 Oct 26;2009 PMID: 21718574Free PMC Article

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