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Benign granular cell tumor

MedGen UID:
44550
•Concept ID:
C0027043
•
Neoplastic Process
Synonyms: Myoblastoma; Myoblastomas
SNOMED CT: Benign granular cell tumor (1336225003)
 
Monarch Initiative: MONDO:0003250

Definition

A granular cell tumor characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Professional guidelines

PubMed

Management of Symptomatic Uterine Leiomyomas: ACOG Practice Bulletin, Number 228.
Obstet Gynecol 2021 Jun 1;137(6):e100-e115. doi: 10.1097/AOG.0000000000004401. PMID: 34011888
Epidemiology and management of uterine fibroids.
Giuliani E, As-Sanie S, Marsh EE
Int J Gynaecol Obstet 2020 Apr;149(1):3-9. Epub 2020 Feb 17 doi: 10.1002/ijgo.13102. PMID: 31960950
Uterine Fibroids: Diagnosis and Treatment.
De La Cruz MS, Buchanan EM
Am Fam Physician 2017 Jan 15;95(2):100-107. PMID: 28084714

Recent clinical studies

Etiology

Endoscopic resection of intrathoracic tumors: experience with and long-term results for 26 patients.
Ponce FA, Killory BD, Wait SD, Theodore N, Dickman CA
J Neurosurg Spine 2011 Mar;14(3):377-81. Epub 2011 Jan 21 doi: 10.3171/2010.11.SPINE09718. PMID: 21250809
Granular cell tumor of the mediastinum.
Machida E, Haniuda M, Eguchi T, Kurai M, Yamanda T, Amano J, Ota H
Intern Med 2003 Feb;42(2):178-81. doi: 10.2169/internalmedicine.42.178. PMID: 12636238

Diagnosis

A Case of Synchronous Malignant and Benign Granular Cell Tumor of the Vulva.
Baranova K, Goebel EA, McGee J, Walsh JC
Int J Gynecol Pathol 2021 Sep 1;40(5):460-464. doi: 10.1097/PGP.0000000000000712. PMID: 32947331
Granular cell tumor presenting in the scrotum of a pediatric patient: a case report and review of the literature.
Richmond AM, La Rosa FG, Said S
J Med Case Rep 2016 Jun 4;10(1):161. doi: 10.1186/s13256-016-0911-x. PMID: 27259474Free PMC Article
Granular cell tumor of the abdominal wall: case report and review of the literature.
Toelen C, Goovaerts G, Huyghe M
Acta Chir Belg 2013 Sep-Oct;113(5):364-6. PMID: 24294803
Benign granular cell tumor of the vulva: first report of multiple cases in a family.
Kardhashi A, Assunta Deliso M, Renna A, Trojano G, Zito FA, Trojano V
Gynecol Obstet Invest 2012;73(4):341-8. Epub 2012 Apr 20 doi: 10.1159/000336256. PMID: 22517025
Benign granular cell tumor of the breast: a misleading disease.
Ventura L, Guadagni S, Ventura T, Di Silvestre K, Coletti G, Leocata P
Tumori 1999 May-Jun;85(3):194-8. doi: 10.1177/030089169908500309. PMID: 10426131

Therapy

Uterine cervical malignant granular cell tumor.
Guo N, Peng Z, Yang K, Lou J
J Obstet Gynaecol Res 2012 Jun;38(6):944-7. Epub 2012 Mar 13 doi: 10.1111/j.1447-0756.2011.01788.x. PMID: 22414028

Prognosis

Granular cell tumor on perianal region: a case report.
Ugur K, Emine M, Sevgi K, Sezgin Z
Acta Med Iran 2013 Aug 7;51(7):509-11. PMID: 23945899
Uterine cervical malignant granular cell tumor.
Guo N, Peng Z, Yang K, Lou J
J Obstet Gynaecol Res 2012 Jun;38(6):944-7. Epub 2012 Mar 13 doi: 10.1111/j.1447-0756.2011.01788.x. PMID: 22414028
Granular cell tumor of the mediastinum.
Machida E, Haniuda M, Eguchi T, Kurai M, Yamanda T, Amano J, Ota H
Intern Med 2003 Feb;42(2):178-81. doi: 10.2169/internalmedicine.42.178. PMID: 12636238
Benign granular cell tumor of the breast: a misleading disease.
Ventura L, Guadagni S, Ventura T, Di Silvestre K, Coletti G, Leocata P
Tumori 1999 May-Jun;85(3):194-8. doi: 10.1177/030089169908500309. PMID: 10426131

Clinical prediction guides

Obstruction of the pancreatic duct by a granular cell tumor.
Sekas G, Talamo TS, Julian TB
Dig Dis Sci 1988 Oct;33(10):1334-7. doi: 10.1007/BF01536688. PMID: 2844481

Recent systematic reviews

Benign granular cell tumor of the vulva: first report of multiple cases in a family.
Kardhashi A, Assunta Deliso M, Renna A, Trojano G, Zito FA, Trojano V
Gynecol Obstet Invest 2012;73(4):341-8. Epub 2012 Apr 20 doi: 10.1159/000336256. PMID: 22517025

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