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Fascioliasis

MedGen UID:
41969
Concept ID:
C0015652
Disease or Syndrome
Synonyms: Fasciola Infection; Fasciola Infections; Fascioliases; Infection, Fasciola; Infections, Fasciola
SNOMED CT: Infection by Fasciola (111922007); Fascioliasis (111922007); Infection caused by Fasciola (111922007)
 
Monarch Initiative: MONDO:0004668

Definition

A parasitic infection that is caused by liver flukes, usually Fasciola hepatica, of sheep, goats, and cattle. Humans become infected by eating uncooked, infested aquatic vegetation (classically watercress). Adult flukes inhabit the bile ducts, gallbladder, and occasionally ectopic sites. Symptoms arise secondary to inflammatory response or obstruction. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFascioliasis

Professional guidelines

PubMed

Marcos L, Maco V, Terashima A
Expert Rev Anti Infect Ther 2021 Jul;19(7):817-823. Epub 2020 Dec 14 doi: 10.1080/14787210.2021.1858798. PMID: 33267701
Gandhi P, Schmitt EK, Chen CW, Samantray S, Venishetty VK, Hughes D
Trans R Soc Trop Med Hyg 2019 Dec 1;113(12):797-804. doi: 10.1093/trstmh/trz093. PMID: 31638149Free PMC Article
Webb CM, Cabada MM
Curr Opin Infect Dis 2018 Oct;31(5):409-414. doi: 10.1097/QCO.0000000000000482. PMID: 30113327

Recent clinical studies

Etiology

Harada Y, Iwashita H, Moriyasu T, Nagi S, Saito N, Sugawara-Mikami M, Yoshioka K, Yotsu R; Japan NTD Study Group
PLoS Negl Trop Dis 2024 Jan;18(1):e0011854. Epub 2024 Jan 2 doi: 10.1371/journal.pntd.0011854. PMID: 38166156Free PMC Article
Wszelaki S, Podobiński P, Środoń K
J Appl Toxicol 2023 Dec;43(12):1778-1792. Epub 2023 Apr 1 doi: 10.1002/jat.4466. PMID: 36987554
Bergquist R, Brattig NW, Chimbari MJ, Zinsstag J, Utzinger J
Acta Trop 2017 Nov;175:1-8. Epub 2017 Jul 18 doi: 10.1016/j.actatropica.2017.07.015. PMID: 28733024
Dietrich CF, Kabaalioglu A, Brunetti E, Richter J
Z Gastroenterol 2015 Apr;53(4):285-90. Epub 2015 Apr 10 doi: 10.1055/s-0034-1385728. PMID: 25860578
Brennan GP, Fairweather I, Trudgett A, Hoey E, McCoy, McConville M, Meaney M, Robinson M, McFerran N, Ryan L, Lanusse C, Mottier L, Alvarez L, Solana H, Virkel G, Brophy PM
Exp Mol Pathol 2007 Apr;82(2):104-9. Epub 2007 Feb 15 doi: 10.1016/j.yexmp.2007.01.009. PMID: 17398281

Diagnosis

Lalrinkima H, Lalchhandama C, Jacob SS, Raina OK, Lallianchhunga MC
Exp Parasitol 2021 Mar;222:108066. Epub 2021 Jan 12 doi: 10.1016/j.exppara.2021.108066. PMID: 33444570
Siles-Lucas M, Becerro-Recio D, Serrat J, González-Miguel J
Res Vet Sci 2021 Jan;134:27-35. Epub 2020 Oct 17 doi: 10.1016/j.rvsc.2020.10.011. PMID: 33278757
Ashjaei B, Farahmand F, Vasei M, Zamani F, Haghi Ashtiani MT, Moradzadeh A, Safavi M
Arch Iran Med 2020 Jun 1;23(6):412-413. doi: 10.34172/aim.2020.36. PMID: 32536180
Saba R, Korkmaz M, Inan D, Mamikoğlu L, Turhan O, Günseren F, Cevikol C, Kabaalioğlu A
Clin Microbiol Infect 2004 May;10(5):385-7. doi: 10.1111/j.1469-0691.2004.00820.x. PMID: 15113313
Osman M, Lausten SB, El-Sefi T, Boghdadi I, Rashed MY, Jensen SL
Dig Surg 1998;15(4):287-96. doi: 10.1159/000018640. PMID: 9845601

Therapy

Mas-Coma S, Valero MA, Bargues MD
Adv Exp Med Biol 2024;1454:157-201. doi: 10.1007/978-3-031-60121-7_5. PMID: 39008266
Chai JY, Jung BK, Hong SJ
Korean J Parasitol 2021 Jun;59(3):189-225. Epub 2021 Jun 21 doi: 10.3347/kjp.2021.59.3.189. PMID: 34218593Free PMC Article
Mas-Coma S, Valero MA, Bargues MD
Adv Exp Med Biol 2014;766:77-114. doi: 10.1007/978-1-4939-0915-5_4. PMID: 24903364
Saba R, Korkmaz M, Inan D, Mamikoğlu L, Turhan O, Günseren F, Cevikol C, Kabaalioğlu A
Clin Microbiol Infect 2004 May;10(5):385-7. doi: 10.1111/j.1469-0691.2004.00820.x. PMID: 15113313
Osman M, Lausten SB, El-Sefi T, Boghdadi I, Rashed MY, Jensen SL
Dig Surg 1998;15(4):287-96. doi: 10.1159/000018640. PMID: 9845601

Prognosis

Modabbernia G, Meshgi B, Kinsley AC
Parasitol Res 2024 Aug 15;123(8):300. doi: 10.1007/s00436-024-08319-6. PMID: 39145846
Lupi O, Downing C, Lee M, Bravo F, Giglio P, Woc-Colburn L, Tyring SK
J Am Acad Dermatol 2015 Dec;73(6):947-57; quiz 957-8. doi: 10.1016/j.jaad.2014.11.035. PMID: 26568338
Lupi O, Downing C, Lee M, Pino L, Bravo F, Giglio P, Sethi A, Klaus S, Sangueza OP, Fuller C, Mendoza N, Ladizinski B, Woc-Colburn L, Tyring SK
J Am Acad Dermatol 2015 Dec;73(6):929-44; quiz 945-6. doi: 10.1016/j.jaad.2014.11.034. PMID: 26568337
Mas-Coma S, Agramunt VH, Valero MA
Adv Parasitol 2014;84:27-149. doi: 10.1016/B978-0-12-800099-1.00002-8. PMID: 24480313
Osman M, Lausten SB, El-Sefi T, Boghdadi I, Rashed MY, Jensen SL
Dig Surg 1998;15(4):287-96. doi: 10.1159/000018640. PMID: 9845601

Clinical prediction guides

Modabbernia G, Meshgi B, Kinsley AC
Parasitol Res 2024 Aug 15;123(8):300. doi: 10.1007/s00436-024-08319-6. PMID: 39145846
Francalanci E, Manciulli T, Bandini G, Blanc P, Bonelli SI, Brunetti E, Gotuzzo E, Cretu CM, Gobbi F, Bartoloni A, Zammarchi L
Acta Parasitol 2023 Dec;68(4):937-941. Epub 2023 Oct 23 doi: 10.1007/s11686-023-00723-9. PMID: 37872438Free PMC Article
Leerapun A, Puasripun S, Kijdamrongthum P, Thongsawat S
Hepatol Int 2021 Jun;15(3):804-811. Epub 2021 Apr 17 doi: 10.1007/s12072-021-10180-z. PMID: 33866512
Corral-Ruiz GM, Sánchez-Torres LE
Acta Trop 2020 Oct;210:105548. Epub 2020 Jun 4 doi: 10.1016/j.actatropica.2020.105548. PMID: 32505597
Mera y Sierra R, Agramunt VH, Cuervo P, Mas-Coma S
Parasit Vectors 2011 Jun 11;4:104. doi: 10.1186/1756-3305-4-104. PMID: 21663691Free PMC Article

Recent systematic reviews

Lan Z, Zhang XH, Xing JL, Zhang AH, Wang HR, Zhang XC, Gao JF, Wang CR
J Glob Health 2024 Sep 19;14:04223. doi: 10.7189/jogh.14.04223. PMID: 39297588Free PMC Article
Hoang Quang V, Levecke B, Do Trung D, Devleesschauwer B, Vu Thi Lam B, Goossens K, Polman K, Callens S, Dorny P, Dermauw V
PLoS Negl Trop Dis 2024 Jan;18(1):e0011904. Epub 2024 Jan 17 doi: 10.1371/journal.pntd.0011904. PMID: 38232120Free PMC Article
Qian MB, Patel C, Palmeirim MS, Wang X, Schindler C, Utzinger J, Zhou XN, Keiser J
Lancet Microbe 2022 Aug;3(8):e616-e624. Epub 2022 Jun 10 doi: 10.1016/S2666-5247(22)00026-X. PMID: 35697047
Bahmaninejad P, Abdi J, Valizadeh R
Infect Disord Drug Targets 2019;19(1):30-35. doi: 10.2174/1871526518666180816102040. PMID: 30113004
Xia J, Jiang SC, Peng HJ
PLoS One 2015;10(7):e0132673. Epub 2015 Jul 17 doi: 10.1371/journal.pone.0132673. PMID: 26186510Free PMC Article

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