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Decalcification, Pathologic

MedGen UID:
4161
•Concept ID:
C0011085
•
Disease or Syndrome
Synonyms: Decalcification, Pathological; Pathologic Decalcification; Pathological Decalcification

Definition

The loss of calcium salts from bones and teeth. Bacteria may be responsible for this occurrence in teeth. Old age may be a factor contributing to calcium loss, as is the presence of diseases such as rheumatoid arthritis. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDecalcification, Pathologic

Professional guidelines

PubMed

Enamel decalcification in orthodontic treatment.
Younis O, Hughes DO, Weber FN
Am J Orthod 1979 Jun;75(6):678-81. doi: 10.1016/0002-9416(79)90099-x. PMID: 377980
Preparations to prevent enamel decalcification during orthodontic treatment compared. An in vitro study.
Hughes DO, Hembree JH Jr, Weber FN
Am J Orthod 1979 Apr;75(4):416-20. doi: 10.1016/0002-9416(79)90163-5. PMID: 285617
Preventing enamel decalcification during orthodontic treatment.
Tillery TJ, Hembree JH Jr, Weber FN
Am J Orthod 1976 Oct;70(4):435-9. doi: 10.1016/0002-9416(76)90116-0. PMID: 788521

Recent clinical studies

Etiology

Adhesives for fixed orthodontic brackets.
Mandall NA, Hickman J, Macfarlane TV, Mattick RC, Millett DT, Worthington HV
Cochrane Database Syst Rev 2018 Apr 9;4(4):CD002282. doi: 10.1002/14651858.CD002282.pub2. PMID: 29630138Free PMC Article
Multimodal fundus imaging in choroidal osteoma.
Navajas EV, Costa RA, Calucci D, Hammoudi DS, Simpson ER, Altomare F
Am J Ophthalmol 2012 May;153(5):890-895.e3. Epub 2012 Jan 21 doi: 10.1016/j.ajo.2011.10.025. PMID: 22265155
Time-dependent decalcifying effects of endodontic irrigants with antibacterial properties.
Sayin TC, Cehreli ZC, Deniz D, Akcay A, Tuncel B, Dagli F, Gozukara H, Kalayci S
J Endod 2009 Feb;35(2):280-3. doi: 10.1016/j.joen.2008.11.016. PMID: 19166790
Protrusio acetabuli in osteoporosis and osteomalacia.
Bible MW, Pinals RS, Palmieri GM, Pitcock JA
Clin Exp Rheumatol 1983 Oct-Dec;1(4):323-6. PMID: 6681149
Preventing enamel decalcification during orthodontic treatment.
Tillery TJ, Hembree JH Jr, Weber FN
Am J Orthod 1976 Oct;70(4):435-9. doi: 10.1016/0002-9416(76)90116-0. PMID: 788521

Diagnosis

Multimodal fundus imaging in choroidal osteoma.
Navajas EV, Costa RA, Calucci D, Hammoudi DS, Simpson ER, Altomare F
Am J Ophthalmol 2012 May;153(5):890-895.e3. Epub 2012 Jan 21 doi: 10.1016/j.ajo.2011.10.025. PMID: 22265155
Temporal bone osteopetrosis.
Wahab Hamed AA, Linthicum FH Jr
Otol Neurotol 2004 Jul;25(4):635. doi: 10.1097/00129492-200407000-00037. PMID: 15241248
Periapical lesions.
Wood NK
Dent Clin North Am 1984 Oct;28(4):725-66. PMID: 6594276
Protrusio acetabuli in osteoporosis and osteomalacia.
Bible MW, Pinals RS, Palmieri GM, Pitcock JA
Clin Exp Rheumatol 1983 Oct-Dec;1(4):323-6. PMID: 6681149
Atlantoaxial dislocations (review).
Pandya SK
Neurol India 1972 Mar;20(1):13-48. PMID: 4264501

Therapy

Adhesives for fixed orthodontic brackets.
Mandall NA, Hickman J, Macfarlane TV, Mattick RC, Millett DT, Worthington HV
Cochrane Database Syst Rev 2018 Apr 9;4(4):CD002282. doi: 10.1002/14651858.CD002282.pub2. PMID: 29630138Free PMC Article
Calcium orthophosphates (CaPO(4)): Occurrence and properties.
Dorozhkin SV
Morphologie 2017 Sep;101(334):125-142. Epub 2017 May 10 doi: 10.1016/j.morpho.2017.03.007. PMID: 28501354
Space flight calcium: implications for astronaut health, spacecraft operations, and Earth.
Smith SM, McCoy T, Gazda D, Morgan JL, Heer M, Zwart SR
Nutrients 2012 Dec 18;4(12):2047-68. doi: 10.3390/nu4122047. PMID: 23250146Free PMC Article
Calcium and bone health in infants.
Koo WW, Warren L
Neonatal Netw 2003 Sep-Oct;22(5):23-37. doi: 10.1891/0730-0832.22.5.23. PMID: 14598978
Prevention in orthodontics--a review.
McGuinness NJ
Dent Update 1992 May;19(4):168-70, 172-5. PMID: 1289157

Prognosis

Risk of Malignancy in Thyroid Nodules with Non-Diagnostic Fine-Needle Aspiration: A Retrospective Cohort Study.
Espinosa De Ycaza AE, Lowe KM, Dean DS, Castro MR, Fatourechi V, Ryder M, Morris JC, Stan MN
Thyroid 2016 Nov;26(11):1598-1604. Epub 2016 Oct 5 doi: 10.1089/thy.2016.0096. PMID: 27549368Free PMC Article
Bilateral choroidal osteoma: visual acuity at 45-year follow-up.
Hasanreisoglu M, Shields JA, Mashayekhi A, Shields CL
Retin Cases Brief Rep 2015 Summer;9(3):239-41. doi: 10.1097/ICB.0000000000000148. PMID: 25790319
Spectral-domain optical coherence tomography of the choroid in choroidal osteoma.
Haruta M, Hangai M, Taguchi C, Yamakawa R
Ophthalmic Surg Lasers Imaging 2011 Dec 8;42 Online:e118-21. doi: 10.3928/15428877-20111201-04. PMID: 22150600
Factors predictive of tumor growth, tumor decalcification, choroidal neovascularization, and visual outcome in 74 eyes with choroidal osteoma.
Shields CL, Sun H, Demirci H, Shields JA
Arch Ophthalmol 2005 Dec;123(12):1658-66. doi: 10.1001/archopht.123.12.1658. PMID: 16344436
Prevention in orthodontics--a review.
McGuinness NJ
Dent Update 1992 May;19(4):168-70, 172-5. PMID: 1289157

Clinical prediction guides

Risk of Malignancy in Thyroid Nodules with Non-Diagnostic Fine-Needle Aspiration: A Retrospective Cohort Study.
Espinosa De Ycaza AE, Lowe KM, Dean DS, Castro MR, Fatourechi V, Ryder M, Morris JC, Stan MN
Thyroid 2016 Nov;26(11):1598-1604. Epub 2016 Oct 5 doi: 10.1089/thy.2016.0096. PMID: 27549368Free PMC Article
Pediatric thyroid nodules: ultrasonographic characteristics and inter-observer variability in prediction of malignancy.
Koltin D, O'Gorman CS, Murphy A, Ngan B, Daneman A, Navarro OM, García C, Atenafu EG, Wasserman JD, Hamilton J, Rachmiel M
J Pediatr Endocrinol Metab 2016 Jul 1;29(7):789-94. doi: 10.1515/jpem-2015-0242. PMID: 27089403
Multimodal fundus imaging in choroidal osteoma.
Navajas EV, Costa RA, Calucci D, Hammoudi DS, Simpson ER, Altomare F
Am J Ophthalmol 2012 May;153(5):890-895.e3. Epub 2012 Jan 21 doi: 10.1016/j.ajo.2011.10.025. PMID: 22265155
Time-dependent decalcifying effects of endodontic irrigants with antibacterial properties.
Sayin TC, Cehreli ZC, Deniz D, Akcay A, Tuncel B, Dagli F, Gozukara H, Kalayci S
J Endod 2009 Feb;35(2):280-3. doi: 10.1016/j.joen.2008.11.016. PMID: 19166790
Factors predictive of tumor growth, tumor decalcification, choroidal neovascularization, and visual outcome in 74 eyes with choroidal osteoma.
Shields CL, Sun H, Demirci H, Shields JA
Arch Ophthalmol 2005 Dec;123(12):1658-66. doi: 10.1001/archopht.123.12.1658. PMID: 16344436

Recent systematic reviews

Adhesives for fixed orthodontic brackets.
Mandall NA, Hickman J, Macfarlane TV, Mattick RC, Millett DT, Worthington HV
Cochrane Database Syst Rev 2018 Apr 9;4(4):CD002282. doi: 10.1002/14651858.CD002282.pub2. PMID: 29630138Free PMC Article

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