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Chronic tic disorder

MedGen UID:
40301
•Concept ID:
C0008701
•
Mental or Behavioral Dysfunction
Synonyms: Chronic Motor or Vocal Tic Disorder; Motor or Vocal Tic Disorder, Chronic; Tic Disorder, Chronic Motor or Vocal
 
Monarch Initiative: MONDO:0001074

Definition

A neurological disorder presenting in childhood that is characterized by either motor or phonic tics, but not both, that occur daily or nearly daily for at least a year and are not attributed to an identifiable cause. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChronic tic disorder

Professional guidelines

PubMed

Comorbid chronic tic disorder and tourette syndrome in children requiring inpatient mental health treatment.
Zinna S, Luxton R, Papachristou E, Dima D, Kyriakopoulos M
Clin Child Psychol Psychiatry 2021 Jul;26(3):894-905. Epub 2021 Apr 16 doi: 10.1177/13591045211007918. PMID: 33860687
Progress in Pharmacological and Surgical Management of Tourette Syndrome and Other Chronic Tic Disorders.
Pandey S, Dash D
Neurologist 2019 May;24(3):93-108. doi: 10.1097/NRL.0000000000000218. PMID: 31045720
Pharmacological treatment for attention deficit hyperactivity disorder (ADHD) in children with comorbid tic disorders.
Osland ST, Steeves TD, Pringsheim T
Cochrane Database Syst Rev 2018 Jun 26;6(6):CD007990. doi: 10.1002/14651858.CD007990.pub3. PMID: 29944175Free PMC Article

Recent clinical studies

Etiology

Early-Life and Family Risk Factors for Tic Disorder Persistence into Adulthood.
Mataix-Cols D, Isomura K, Brander G, Brikell I, Lichtenstein P, Chang Z, Larsson H, Kuja-Halkola R, Black KJ, Sidorchuk A, Fernández de la Cruz L
Mov Disord 2023 Aug;38(8):1419-1427. Epub 2023 May 29 doi: 10.1002/mds.29454. PMID: 37246931
Use of Nutritional Supplements Based on L-Theanine and Vitamin B6 in Children with Tourette Syndrome, with Anxiety Disorders: A Pilot Study.
Rizzo R, Prato A, Scerbo M, Saia F, Barone R, Curatolo P
Nutrients 2022 Feb 18;14(4) doi: 10.3390/nu14040852. PMID: 35215501Free PMC Article
Insomnia in Tourette Syndrome and Chronic Tic Disorder.
Isomura K, Sidorchuk A, Sevilla-Cermeño L, Åkerstedt T, Silverberg-Morse M, Larsson H, Mataix-Cols D, Fernández de la Cruz L
Mov Disord 2022 Feb;37(2):392-400. Epub 2021 Oct 24 doi: 10.1002/mds.28842. PMID: 34693569
Pharmacological treatment for attention deficit hyperactivity disorder (ADHD) in children with comorbid tic disorders.
Osland ST, Steeves TD, Pringsheim T
Cochrane Database Syst Rev 2018 Jun 26;6(6):CD007990. doi: 10.1002/14651858.CD007990.pub3. PMID: 29944175Free PMC Article
Attention deficit hyperactivity disorder, chronic tic disorder, and methylphenidate.
Gadow KD, Sverd J
Adv Neurol 2006;99:197-207. PMID: 16536367

Diagnosis

Early-Life and Family Risk Factors for Tic Disorder Persistence into Adulthood.
Mataix-Cols D, Isomura K, Brander G, Brikell I, Lichtenstein P, Chang Z, Larsson H, Kuja-Halkola R, Black KJ, Sidorchuk A, Fernández de la Cruz L
Mov Disord 2023 Aug;38(8):1419-1427. Epub 2023 May 29 doi: 10.1002/mds.29454. PMID: 37246931
Functional tic-like presentations differ strikingly from Provisional Tic Disorder.
Arbuckle AL, Bihun EC, Schlaggar BL, Black KJ
F1000Res 2022;11:1566. Epub 2023 Apr 17 doi: 10.12688/f1000research.129252.2. PMID: 37224324Free PMC Article
Childhood Neurologic Conditions: Movement Disorders.
Youssef P
FP Essent 2022 Dec;523:20-26. PMID: 36459665
Insomnia in Tourette Syndrome and Chronic Tic Disorder.
Isomura K, Sidorchuk A, Sevilla-Cermeño L, Åkerstedt T, Silverberg-Morse M, Larsson H, Mataix-Cols D, Fernández de la Cruz L
Mov Disord 2022 Feb;37(2):392-400. Epub 2021 Oct 24 doi: 10.1002/mds.28842. PMID: 34693569
Comorbid chronic tic disorder and tourette syndrome in children requiring inpatient mental health treatment.
Zinna S, Luxton R, Papachristou E, Dima D, Kyriakopoulos M
Clin Child Psychol Psychiatry 2021 Jul;26(3):894-905. Epub 2021 Apr 16 doi: 10.1177/13591045211007918. PMID: 33860687

Therapy

Use of Nutritional Supplements Based on L-Theanine and Vitamin B6 in Children with Tourette Syndrome, with Anxiety Disorders: A Pilot Study.
Rizzo R, Prato A, Scerbo M, Saia F, Barone R, Curatolo P
Nutrients 2022 Feb 18;14(4) doi: 10.3390/nu14040852. PMID: 35215501Free PMC Article
Progress in Pharmacological and Surgical Management of Tourette Syndrome and Other Chronic Tic Disorders.
Pandey S, Dash D
Neurologist 2019 May;24(3):93-108. doi: 10.1097/NRL.0000000000000218. PMID: 31045720
Pharmacological treatment for attention deficit hyperactivity disorder (ADHD) in children with comorbid tic disorders.
Osland ST, Steeves TD, Pringsheim T
Cochrane Database Syst Rev 2018 Jun 26;6(6):CD007990. doi: 10.1002/14651858.CD007990.pub3. PMID: 29944175Free PMC Article
Attention deficit hyperactivity disorder, chronic tic disorder, and methylphenidate.
Gadow KD, Sverd J
Adv Neurol 2006;99:197-207. PMID: 16536367
Pharmacodynamics of ziprasidone in children and adolescents: impact on dopamine transmission.
Sallee FR, Gilbert DL, Vinks AA, Miceli JJ, Robarge L, Wilner K
J Am Acad Child Adolesc Psychiatry 2003 Aug;42(8):902-7. doi: 10.1097/01.CHI.0000046897.27264.46. PMID: 12874491

Prognosis

Functional tic-like presentations differ strikingly from Provisional Tic Disorder.
Arbuckle AL, Bihun EC, Schlaggar BL, Black KJ
F1000Res 2022;11:1566. Epub 2023 Apr 17 doi: 10.12688/f1000research.129252.2. PMID: 37224324Free PMC Article
Cross-disorder comparison of sensory over-responsivity in chronic tic disorders and obsessive-compulsive disorder.
Isaacs D, Key AP, Cascio CJ, Conley AC, Riordan H, Walker HC, Wallace MT, Claassen DO
Compr Psychiatry 2022 Feb;113:152291. Epub 2021 Dec 17 doi: 10.1016/j.comppsych.2021.152291. PMID: 34952304Free PMC Article
Suicide in Tourette's and Chronic Tic Disorders.
Fernández de la Cruz L, Rydell M, Runeson B, Brander G, Rück C, D'Onofrio BM, Larsson H, Lichtenstein P, Mataix-Cols D
Biol Psychiatry 2017 Jul 15;82(2):111-118. Epub 2016 Aug 26 doi: 10.1016/j.biopsych.2016.08.023. PMID: 27773353
Attention deficit hyperactivity disorder, chronic tic disorder, and methylphenidate.
Gadow KD, Sverd J
Adv Neurol 2006;99:197-207. PMID: 16536367
Tourette syndrome: prediction of phenotypic variation in monozygotic twins by caudate nucleus D2 receptor binding.
Wolf SS, Jones DW, Knable MB, Gorey JG, Lee KS, Hyde TM, Coppola R, Weinberger DR
Science 1996 Aug 30;273(5279):1225-7. doi: 10.1126/science.273.5279.1225. PMID: 8703056

Clinical prediction guides

Psychosocial stress in children with Tourette syndrome and chronic tic disorder.
Tan CY, Chiu NC, Zeng YH, Huang JY, Tzang RF, Chen HJ, Lin YJ, Sun FJ, Ho CS
Pediatr Neonatol 2024 Jul;65(4):336-340. Epub 2023 Nov 14 doi: 10.1016/j.pedneo.2023.06.011. PMID: 38000929
Early-Life and Family Risk Factors for Tic Disorder Persistence into Adulthood.
Mataix-Cols D, Isomura K, Brander G, Brikell I, Lichtenstein P, Chang Z, Larsson H, Kuja-Halkola R, Black KJ, Sidorchuk A, Fernández de la Cruz L
Mov Disord 2023 Aug;38(8):1419-1427. Epub 2023 May 29 doi: 10.1002/mds.29454. PMID: 37246931
Functional tic-like presentations differ strikingly from Provisional Tic Disorder.
Arbuckle AL, Bihun EC, Schlaggar BL, Black KJ
F1000Res 2022;11:1566. Epub 2023 Apr 17 doi: 10.12688/f1000research.129252.2. PMID: 37224324Free PMC Article
Cross-disorder comparison of sensory over-responsivity in chronic tic disorders and obsessive-compulsive disorder.
Isaacs D, Key AP, Cascio CJ, Conley AC, Riordan H, Walker HC, Wallace MT, Claassen DO
Compr Psychiatry 2022 Feb;113:152291. Epub 2021 Dec 17 doi: 10.1016/j.comppsych.2021.152291. PMID: 34952304Free PMC Article
Tourette syndrome: prediction of phenotypic variation in monozygotic twins by caudate nucleus D2 receptor binding.
Wolf SS, Jones DW, Knable MB, Gorey JG, Lee KS, Hyde TM, Coppola R, Weinberger DR
Science 1996 Aug 30;273(5279):1225-7. doi: 10.1126/science.273.5279.1225. PMID: 8703056

Recent systematic reviews

A systematic review and meta-analysis of the association between maternal polycystic ovary syndrome and neuropsychiatric disorders in children.
Dubey P, Thakur B, Rodriguez S, Cox J, Sanchez S, Fonseca A, Reddy S, Clegg D, Dwivedi AK
Transl Psychiatry 2021 Nov 8;11(1):569. doi: 10.1038/s41398-021-01699-8. PMID: 34750348Free PMC Article
Rage attacks in Tourette Syndrome and Chronic Tic Disorder: a systematic review.
Conte G, Valente F, Fioriello F, Cardona F
Neurosci Biobehav Rev 2020 Dec;119:21-36. Epub 2020 Sep 25 doi: 10.1016/j.neubiorev.2020.09.019. PMID: 32980398
Streptococcal Infections and Exacerbations in PANDAS: A Systematic Review and Meta-analysis.
Nielsen MØ, Köhler-Forsberg O, Hjorthøj C, Benros ME, Nordentoft M, Orlovska-Waast S
Pediatr Infect Dis J 2019 Feb;38(2):189-194. doi: 10.1097/INF.0000000000002218. PMID: 30325890
Pharmacological treatment for attention deficit hyperactivity disorder (ADHD) in children with comorbid tic disorders.
Osland ST, Steeves TD, Pringsheim T
Cochrane Database Syst Rev 2018 Jun 26;6(6):CD007990. doi: 10.1002/14651858.CD007990.pub3. PMID: 29944175Free PMC Article
The prevalence of tic disorders for children in China: A systematic review and meta-analysis.
Yang C, Zhang L, Zhu P, Zhu C, Guo Q
Medicine (Baltimore) 2016 Jul;95(30):e4354. doi: 10.1097/MD.0000000000004354. PMID: 27472724Free PMC Article

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