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Cleft vertebral arch

MedGen UID:
395267
•Concept ID:
C1859458
•
Congenital Abnormality; Finding
Synonym: Cleft vertebral arches
 
HPO: HP:0004616

Definition

A discontinuity of the vertebral arch, i.e., of the posterior part of a vertebra. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCleft vertebral arch

Conditions with this feature

Osteodysplastic primordial dwarfism, type 1
MedGen UID:
347149
•Concept ID:
C1859452
•
Disease or Syndrome
Microcephalic osteodysplastic primordial dwarfism type I (MOPD1) is a severe autosomal recessive skeletal dysplasia characterized by dwarfism, microcephaly, and neurologic abnormalities, including mental retardation, brain malformations, and ocular/auditory sensory deficits. Patients often die in early childhood (summary by Pierce and Morse, 2012).
See: Condition Record
Osteodysplastic primordial dwarfism, type 1

Professional guidelines

PubMed

A novel bone cement screw system combined with vertebroplasty for the treatment of Kummell disease with bone deficiency at the vertebral anterior border: A minimum 3-year follow-up study.
Wang B, Wang Y, Zhang H, Yan L, Kong L, He S, Hao D
Clin Neurol Neurosurg 2021 Feb;201:106434. Epub 2020 Dec 17 doi: 10.1016/j.clineuro.2020.106434. PMID: 33370625
Risk factors for conservative treatment failure in acute osteoporotic vertebral compression fractures (OVCFs).
Zhang J, He X, Fan Y, Du J, Hao D
Arch Osteoporos 2019 Feb 26;14(1):24. doi: 10.1007/s11657-019-0563-8. PMID: 30806831
Percutaneous Kyphoplasty for the Treatment of Osteoporotic Vertebral Fractures With Intravertebral Fluid or Air: A Comparative Study.
Niu J, Song D, Zhou H, Meng Q, Meng B, Yang H
Clin Spine Surg 2017 Oct;30(8):367-373. doi: 10.1097/BSD.0000000000000262. PMID: 28937459

Recent clinical studies

Etiology

Development and validation of a machine learning model to predict imminent new vertebral fractures after vertebral augmentation.
Jiang Y, Cai J, Zeng Y, Ye H, Yang T, Liu Z, Liu Q
BMC Musculoskelet Disord 2023 Jun 9;24(1):472. doi: 10.1186/s12891-023-06557-w. PMID: 37296426Free PMC Article
Morphological changes of vertebral compression fracture with intra-vertebral cleft treated with percutaneous vertebroplasty.
Park SM, Park JW, Kim H, Kim HJ, Yeom JS, Lee CK, Chang BS
J Orthop Sci 2018 Mar;23(2):237-247. Epub 2017 Nov 23 doi: 10.1016/j.jos.2017.11.006. PMID: 29174421
Risk factors for new vertebral compression fractures after vertebroplasty: a meta-analysis.
Cao J, Kong L, Meng F, Zhang Y, Shen Y
ANZ J Surg 2016 Jul;86(7-8):549-54. Epub 2016 Jan 7 doi: 10.1111/ans.13428. PMID: 26749512
Congenital abnormalities associated with limb deficiency defects: a population study based on cases from the Hungarian Congenital Malformation Registry (1975-1984).
Evans JA, Vitez M, Czeizel A
Am J Med Genet 1994 Jan 1;49(1):52-66. doi: 10.1002/ajmg.1320490111. PMID: 8172251
Rhizomelic chondrodysplasia punctata and survival beyond one year: a review of the literature and five case reports.
Wardinsky TD, Pagon RA, Powell BR, McGillivray B, Stephan M, Zonana J, Moser A
Clin Genet 1990 Aug;38(2):84-93. doi: 10.1111/j.1399-0004.1990.tb03554.x. PMID: 2208770

Diagnosis

Anatomical and biomechanical characteristics of basivertebral foramen and its clinical significance.
Li S, Zhao X
Zhejiang Da Xue Xue Bao Yi Xue Ban 2024 Aug 25;53(4):443-449. doi: 10.3724/zdxbyxb-2024-0220. PMID: 39183068Free PMC Article
Butterfly Vertebra: A Retrospective Study of 30 Patients.
Xie B, Yan T, Ni H, Zhu K, Zhang S, Song P, Xu P, Shen C, Dong F
World Neurosurg 2024 May;185:e995-e1003. Epub 2024 Mar 9 doi: 10.1016/j.wneu.2024.03.009. PMID: 38462068
Risk factors for secondary fractures to percutaneous vertebroplasty for osteoporotic vertebral compression fractures: a systematic review.
Mao W, Dong F, Huang G, He P, Chen H, Qin S, Li A
J Orthop Surg Res 2021 Oct 30;16(1):644. doi: 10.1186/s13018-021-02722-w. PMID: 34717682Free PMC Article
Multi-level sagittally cleft vertebrae: a case report and review of the literature.
Zeoli T, Iwanaga J, Dumont AS, Tubbs RS
Surg Radiol Anat 2021 Jan;43(1):127-130. Epub 2020 Jun 14 doi: 10.1007/s00276-020-02517-4. PMID: 32537674
Avascular necrosis of the vertebral body: MR imaging.
Naul LG, Peet GJ, Maupin WB
Radiology 1989 Jul;172(1):219-22. doi: 10.1148/radiology.172.1.2740507. PMID: 2740507

Therapy

Development and validation of a machine learning model to predict imminent new vertebral fractures after vertebral augmentation.
Jiang Y, Cai J, Zeng Y, Ye H, Yang T, Liu Z, Liu Q
BMC Musculoskelet Disord 2023 Jun 9;24(1):472. doi: 10.1186/s12891-023-06557-w. PMID: 37296426Free PMC Article
CT-Guided Percutaneous Vertebroplasty for Vertebral Non-union Following Posterior Fixation: A Preliminary Retrospective Study.
Pavan LJ, Dalili D, Ranc C, Torre F, Clerk-Lamalice O, Burns R, Andreani O, Ranc PA, Bronsard N, Prestat A, Amoretti N
Cardiovasc Intervent Radiol 2022 May;45(5):687-695. Epub 2022 Jan 22 doi: 10.1007/s00270-021-03037-3. PMID: 35064285
Does the Relationship Between Bone Cement and the Intravertebral Cleft of Kummell Disease Affect the Efficacy of PKP?
Lv NN, Hou MZ, Zhou ZZ, Feng XX, Liu HJ, Shan FR, Li EH, Guan BY, He SJ, Liu MM
World Neurosurg 2022 Apr;160:e430-e435. Epub 2022 Jan 18 doi: 10.1016/j.wneu.2022.01.050. PMID: 35051635
Risk factors for new vertebral compression fractures after vertebroplasty: a meta-analysis.
Cao J, Kong L, Meng F, Zhang Y, Shen Y
ANZ J Surg 2016 Jul;86(7-8):549-54. Epub 2016 Jan 7 doi: 10.1111/ans.13428. PMID: 26749512
Refracture with cement extrusion following percutaneous vertebroplasty of a large interbody cleft.
Wagner AL, Baskurt E
AJNR Am J Neuroradiol 2006 Jan;27(1):230-1. PMID: 16418390Free PMC Article

Prognosis

Development and validation of a machine learning model to predict imminent new vertebral fractures after vertebral augmentation.
Jiang Y, Cai J, Zeng Y, Ye H, Yang T, Liu Z, Liu Q
BMC Musculoskelet Disord 2023 Jun 9;24(1):472. doi: 10.1186/s12891-023-06557-w. PMID: 37296426Free PMC Article
Morphological changes of vertebral compression fracture with intra-vertebral cleft treated with percutaneous vertebroplasty.
Park SM, Park JW, Kim H, Kim HJ, Yeom JS, Lee CK, Chang BS
J Orthop Sci 2018 Mar;23(2):237-247. Epub 2017 Nov 23 doi: 10.1016/j.jos.2017.11.006. PMID: 29174421
Risk factors for new vertebral compression fractures after vertebroplasty: a meta-analysis.
Cao J, Kong L, Meng F, Zhang Y, Shen Y
ANZ J Surg 2016 Jul;86(7-8):549-54. Epub 2016 Jan 7 doi: 10.1111/ans.13428. PMID: 26749512
A case of split notochord syndrome: presence of dorsal enteric diverticulum adjacent to the dorsal enteric fistula.
Akgür FM, Ozdemir T, Olguner M, Erbayraktar S, Ozer E, Aktuğ T
J Pediatr Surg 1998 Aug;33(8):1317-9. doi: 10.1016/s0022-3468(98)90179-8. PMID: 9722015
Rhizomelic chondrodysplasia punctata and survival beyond one year: a review of the literature and five case reports.
Wardinsky TD, Pagon RA, Powell BR, McGillivray B, Stephan M, Zonana J, Moser A
Clin Genet 1990 Aug;38(2):84-93. doi: 10.1111/j.1399-0004.1990.tb03554.x. PMID: 2208770

Clinical prediction guides

Development and validation of a machine learning model to predict imminent new vertebral fractures after vertebral augmentation.
Jiang Y, Cai J, Zeng Y, Ye H, Yang T, Liu Z, Liu Q
BMC Musculoskelet Disord 2023 Jun 9;24(1):472. doi: 10.1186/s12891-023-06557-w. PMID: 37296426Free PMC Article
Development and internal validation of a clinical prediction model for acute adjacent vertebral fracture after vertebral augmentation : the AVA score.
Hijikata Y, Kamitani T, Nakahara M, Kumamoto S, Sakai T, Itaya T, Yamazaki H, Ogawa Y, Kusumegi A, Inoue T, Yoshida T, Furue N, Fukuhara SI, Yamamoto Y; AVA Score Research Group
Bone Joint J 2022 Jan;104-B(1):97-102. doi: 10.1302/0301-620X.104B1.BJJ-2021-0151.R3. PMID: 34969274
Morphological changes of vertebral compression fracture with intra-vertebral cleft treated with percutaneous vertebroplasty.
Park SM, Park JW, Kim H, Kim HJ, Yeom JS, Lee CK, Chang BS
J Orthop Sci 2018 Mar;23(2):237-247. Epub 2017 Nov 23 doi: 10.1016/j.jos.2017.11.006. PMID: 29174421
Intravertebral Vacuum Cleft and Its Varied Locations within Osteoporotic Vertebral Compression Fractures: Effect on Therapeutic Efficacy.
Yu W, Jiang X, Liang D, Yao Z, Qiu T, Ye L, Zhang S, Jin D
Pain Physician 2017 Sep;20(6):E979-E986. PMID: 28934802
Intradermal dermoid cyst associated with occult spinal dysraphism.
Misago N, Abe M, Kohda H
J Dermatol 1996 Apr;23(4):275-8. doi: 10.1111/j.1346-8138.1996.tb04012.x. PMID: 8935344

Recent systematic reviews

Risk factors for secondary fractures to percutaneous vertebroplasty for osteoporotic vertebral compression fractures: a systematic review.
Mao W, Dong F, Huang G, He P, Chen H, Qin S, Li A
J Orthop Surg Res 2021 Oct 30;16(1):644. doi: 10.1186/s13018-021-02722-w. PMID: 34717682Free PMC Article

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