U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Wide femoral metaphysis

MedGen UID:
355309
•Concept ID:
C1864854
•
Anatomical Abnormality; Finding
Synonym: Broad femoral metaphyses
 
HPO: HP:0006417

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVWide femoral metaphysis

Conditions with this feature

Camptodactyly-tall stature-scoliosis-hearing loss syndrome
MedGen UID:
355844
•Concept ID:
C1864852
•
Disease or Syndrome
This syndrome has characteristics of camptodactyly, tall stature, scoliosis, and hearing loss (CATSHL). It has been described in around 30 individuals from seven generations of the same family. The syndrome is caused by a missense mutation in the FGFR3 gene, leading to a partial loss of function of the encoded protein, which is a negative regulator of bone growth.
See: Condition Record
Camptodactyly-tall stature-scoliosis-hearing loss syndrome

Recent clinical studies

Etiology

Does the Clinical Presentation of Secondary Osteosarcoma in Patients Who Survive Retinoblastoma Differ From That of Conventional Osteosarcoma and How Do We Detect Them?
Kim Y, Park JW, Cho HS, Jang WY, Han I, Kim HS
Clin Orthop Relat Res 2023 Nov 1;481(11):2154-2163. Epub 2023 May 5 doi: 10.1097/CORR.0000000000002667. PMID: 37145140Free PMC Article
Total Hip Arthroplasty for Secondary Coxarthrosis in Patients with Hereditary Multiple Exostoses: Minimum 5-Year Follow-up Results and Surgical Considerations.
Yoon JY, Park CW, Park YS, Yoo JJ, Kim HJ
Clin Orthop Surg 2020 Dec;12(4):435-441. Epub 2020 Nov 18 doi: 10.4055/cios20044. PMID: 33274019Free PMC Article
The short stem: promises and pitfalls.
Stulberg SD, Patel RM
Bone Joint J 2013 Nov;95-B(11 Suppl A):57-62. doi: 10.1302/0301-620X.95B11.32936. PMID: 24187354
Stable, dependable fixation of short-stem femoral implants at 5 years.
Patel RM, Lo WM, Cayo MA, Dolan MM, Stulberg SD
Orthopedics 2013 Mar;36(3):e301-7. doi: 10.3928/01477447-20130222-18. PMID: 23464949
The periphysis and its effect on the metaphysis: I. Definition and normal radiographic pattern.
Oestreich AE, Ahmad BS
Skeletal Radiol 1992;21(5):283-6. doi: 10.1007/BF00241764. PMID: 1502578

Diagnosis

Does the Clinical Presentation of Secondary Osteosarcoma in Patients Who Survive Retinoblastoma Differ From That of Conventional Osteosarcoma and How Do We Detect Them?
Kim Y, Park JW, Cho HS, Jang WY, Han I, Kim HS
Clin Orthop Relat Res 2023 Nov 1;481(11):2154-2163. Epub 2023 May 5 doi: 10.1097/CORR.0000000000002667. PMID: 37145140Free PMC Article
Intramedullary Well-differentiated Osteosarcoma: Imaging and Pathologic Findings in 17 Patients.
Han SM, Wu Y, Wen JX, Wu TH, Sun T, Yu BH, Wu WJ, Gao BL
Curr Med Imaging 2022;18(14):1453-1461. doi: 10.2174/1573405618666211222160039. PMID: 34951370
What's New in Pediatric Hip?
Schmitz MR, Blumberg TJ, Nelson SE, Sees JP, Sankar WN
J Pediatr Orthop 2018 Jul;38(6):e300-e304. doi: 10.1097/BPO.0000000000001166. PMID: 29554020
Multicentric osteosarcoma with long-term survival.
Aizawa T, Okada K, Abe E, Tsuchida S, Shimada Y, Itoi E
Skeletal Radiol 2004 Jan;33(1):41-5. Epub 2003 Nov 20 doi: 10.1007/s00256-003-0717-y. PMID: 14628102
Primary alveolar soft part sarcoma of bone.
Park YK, Unni KK, Kim YW, Han CS, Yang MH, Wenger DE, Sim FH, Lucas DR, Ryan JR, Nadim YA, Nojima T, Fletcher CD
Histopathology 1999 Nov;35(5):411-7. doi: 10.1046/j.1365-2559.1999.035005411.x. PMID: 10583555

Therapy

Revision of total hip arthroplasty by long locking stem with fully hydroxyapatite-coated modular metaphysis (Reef™): A continuous series of 78 cases at a minimum 2-year follow-up.
de Leissegues T, Viste A, Fessy MH
Orthop Traumatol Surg Res 2024 Apr;110(2):103786. Epub 2023 Dec 7 doi: 10.1016/j.otsr.2023.103786. PMID: 38070731
Trans-Metaphyseal Screws Placed in Children: An Argument for Monitoring and Potentially Removing the Implants.
Gamble JG, Ziino C, Imrie MN, Young JL
J Pediatr Orthop 2019 Jan;39(1):e28-e31. doi: 10.1097/BPO.0000000000001280. PMID: 30379707
Parosteal osteosarcoma of the posterior aspect of the distal part of the femur. Oncological and functional results following a new resection technique.
Lewis VO, Gebhardt MC, Springfield DS
J Bone Joint Surg Am 2000 Aug;82(8):1083-8. doi: 10.2106/00004623-200008000-00003. PMID: 10954096
Distal loss of femoral bone following total knee arthroplasty. Measurement with visual and computer-processing of roentgenograms and dual-energy x-ray absorptiometry.
Robertson DD, Mintzer CM, Weissman BN, Ewald FC, LeBoff M, Spector M
J Bone Joint Surg Am 1994 Jan;76(1):66-76. doi: 10.2106/00004623-199401000-00009. PMID: 8288667

Prognosis

Revision of total hip arthroplasty by long locking stem with fully hydroxyapatite-coated modular metaphysis (Reef™): A continuous series of 78 cases at a minimum 2-year follow-up.
de Leissegues T, Viste A, Fessy MH
Orthop Traumatol Surg Res 2024 Apr;110(2):103786. Epub 2023 Dec 7 doi: 10.1016/j.otsr.2023.103786. PMID: 38070731
Intramedullary Well-differentiated Osteosarcoma: Imaging and Pathologic Findings in 17 Patients.
Han SM, Wu Y, Wen JX, Wu TH, Sun T, Yu BH, Wu WJ, Gao BL
Curr Med Imaging 2022;18(14):1453-1461. doi: 10.2174/1573405618666211222160039. PMID: 34951370
Total Hip Arthroplasty for Secondary Coxarthrosis in Patients with Hereditary Multiple Exostoses: Minimum 5-Year Follow-up Results and Surgical Considerations.
Yoon JY, Park CW, Park YS, Yoo JJ, Kim HJ
Clin Orthop Surg 2020 Dec;12(4):435-441. Epub 2020 Nov 18 doi: 10.4055/cios20044. PMID: 33274019Free PMC Article
The short stem: promises and pitfalls.
Stulberg SD, Patel RM
Bone Joint J 2013 Nov;95-B(11 Suppl A):57-62. doi: 10.1302/0301-620X.95B11.32936. PMID: 24187354
Diversity of proximal femoral medullary canal.
Laine HJ, Lehto MU, Moilanen T
J Arthroplasty 2000 Jan;15(1):86-92. doi: 10.1016/s0883-5403(00)91311-1. PMID: 10654468

Clinical prediction guides

Does the Clinical Presentation of Secondary Osteosarcoma in Patients Who Survive Retinoblastoma Differ From That of Conventional Osteosarcoma and How Do We Detect Them?
Kim Y, Park JW, Cho HS, Jang WY, Han I, Kim HS
Clin Orthop Relat Res 2023 Nov 1;481(11):2154-2163. Epub 2023 May 5 doi: 10.1097/CORR.0000000000002667. PMID: 37145140Free PMC Article
Total Hip Arthroplasty for Secondary Coxarthrosis in Patients with Hereditary Multiple Exostoses: Minimum 5-Year Follow-up Results and Surgical Considerations.
Yoon JY, Park CW, Park YS, Yoo JJ, Kim HJ
Clin Orthop Surg 2020 Dec;12(4):435-441. Epub 2020 Nov 18 doi: 10.4055/cios20044. PMID: 33274019Free PMC Article
Salvage Reconstruction With the Masquelet Technique Following Wide Resection for Chondrosarcoma of the Proximal Femoral Metaphysis: A Case Report.
Hakozaki M, Kawakami R, Sasaki N, Toshiki N, Kaneuchi Y, Yamada H, Konno S
In Vivo 2020 Nov-Dec;34(6):3495-3501. doi: 10.21873/invivo.12190. PMID: 33144459Free PMC Article
Stable, dependable fixation of short-stem femoral implants at 5 years.
Patel RM, Lo WM, Cayo MA, Dolan MM, Stulberg SD
Orthopedics 2013 Mar;36(3):e301-7. doi: 10.3928/01477447-20130222-18. PMID: 23464949
Diversity of proximal femoral medullary canal.
Laine HJ, Lehto MU, Moilanen T
J Arthroplasty 2000 Jan;15(1):86-92. doi: 10.1016/s0883-5403(00)91311-1. PMID: 10654468

Supplemental Content

Table of contents

    Clinical resources

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...