Full Report

Format

Full Report
Summary (Text)
Summary (XML)

Send to:

Choose Destination

File
Clipboard
Collections

Bone Leiomyoma

MedGen UID:: 353430
•Concept ID:: C1706980
•: Neoplastic Process

Definition

A rare leiomyoma affecting the bone. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVBone Leiomyoma

Benign neoplasm
- Benign connective and soft tissue neoplasm
  - Benign soft tissue neoplasm
    - Benign muscle neoplasm
      - Benign smooth muscle neoplasm
        Leiomyoma
        Bone Leiomyoma

Professional guidelines

PubMed

Experimental and new investigational drugs for the treatment of uterine fibroids.

Evangelisti G, Ferrero S, Perrone U, Gustavino C, Volpi E, Izzotti A, Barra F
Expert Opin Investig Drugs 2024 May;33(5):497-508. Epub 2024 Apr 17 doi: 10.1080/13543784.2024.2343786. PMID: 38618931

New treatment options for nonsurgical management of uterine fibroids.

Lee S, Stewart EA
Curr Opin Obstet Gynecol 2023 Aug 1;35(4):288-293. Epub 2023 May 3 doi: 10.1097/GCO.0000000000000880. PMID: 37144584 Free PMC Article

EMAS position statement: management of uterine fibroids.

Pérez-López FR, Ornat L, Ceausu I, Depypere H, Erel CT, Lambrinoudaki I, Schenck-Gustafsson K, Simoncini T, Tremollieres F, Rees M; EMAS
Maturitas 2014 Sep;79(1):106-16. Epub 2014 Jun 9 doi: 10.1016/j.maturitas.2014.06.002. PMID: 24975954

See all (28)

Recent clinical studies

Etiology

Long-term Relugolix Combination Therapy for Symptomatic Uterine Leiomyomas.

Al-Hendy A, Lukes AS, Poindexter AN 3rd, Venturella R, Villarroel C, McKain L, Li Y, Wagman RB, Stewart EA
Obstet Gynecol 2022 Dec 1;140(6):920-930. Epub 2022 Nov 2 doi: 10.1097/AOG.0000000000004988. PMID: 36357960 Free PMC Article

Linzagolix with and without hormonal add-back therapy for the treatment of symptomatic uterine fibroids: two randomised, placebo-controlled, phase 3 trials.

Donnez J, Taylor HS, Stewart EA, Bradley L, Marsh E, Archer D, Al-Hendy A, Petraglia F, Watts N, Gotteland JP, Bestel E, Terrill P, Loumaye E, Humberstone A, Garner E
Lancet 2022 Sep 17;400(10356):896-907. doi: 10.1016/S0140-6736(22)01475-1. PMID: 36116480

Treatment of Uterine Fibroid Symptoms with Relugolix Combination Therapy.

Al-Hendy A, Lukes AS, Poindexter AN 3rd, Venturella R, Villarroel C, Critchley HOD, Li Y, McKain L, Arjona Ferreira JC, Langenberg AGM, Wagman RB, Stewart EA
N Engl J Med 2021 Feb 18;384(7):630-642. doi: 10.1056/NEJMoa2008283. PMID: 33596357 Free PMC Article

Short-term and long-term effects of tibolone in postmenopausal women.

Formoso G, Perrone E, Maltoni S, Balduzzi S, Wilkinson J, Basevi V, Marata AM, Magrini N, D'Amico R, Bassi C, Maestri E
Cochrane Database Syst Rev 2016 Oct 12;10(10):CD008536. doi: 10.1002/14651858.CD008536.pub3. PMID: 27733017 Free PMC Article

Vitamin D and female fertility.

Lerchbaum E, Rabe T
Curr Opin Obstet Gynecol 2014 Jun;26(3):145-50. doi: 10.1097/GCO.0000000000000065. PMID: 24717915

See all (114)

Diagnosis

Magnetic Resonance-Guided High-Intensity Focused Ultrasound (MR-HIFU): Technical Background and Overview of Current Clinical Applications (Part 1).

Siedek F, Yeo SY, Heijman E, Grinstein O, Bratke G, Heneweer C, Puesken M, Persigehl T, Maintz D, Grüll H
Rofo 2019 Jun;191(6):522-530. Epub 2019 Jan 10 doi: 10.1055/a-0817-5645. PMID: 30630200

Indications for morcellation in gynecologic surgery.

Parker WH
Curr Opin Obstet Gynecol 2018 Feb;30(1):75-80. doi: 10.1097/GCO.0000000000000427. PMID: 29251677

Short-term and long-term effects of tibolone in postmenopausal women.

Soft tissue tumors with muscle differentiation.

Davies CE, Davies AM, Kindblom LG, James SL
Semin Musculoskelet Radiol 2010 Jun;14(2):245-56. Epub 2010 May 18 doi: 10.1055/s-0030-1253165. PMID: 20486032

Frontal intradiploic angioleiomyoma.

Vijayasaradhi M, Uppin SG, Sreedhar V, Sundaram C, Panigrahi MK
J Neurosurg Pediatr 2008 Oct;2(4):266-8. doi: 10.3171/PED.2008.2.10.266. PMID: 18831661

See all (171)

Therapy

Long-term Relugolix Combination Therapy for Symptomatic Uterine Leiomyomas.

Relugolix/Estradiol/Norethisterone (Norethindrone) Acetate: A Review in Symptomatic Uterine Fibroids.

Syed YY
Drugs 2022 Oct;82(15):1549-1556. Epub 2022 Nov 4 doi: 10.1007/s40265-022-01790-4. PMID: 36331779 Free PMC Article

Linzagolix with and without hormonal add-back therapy for the treatment of symptomatic uterine fibroids: two randomised, placebo-controlled, phase 3 trials.

Treatment of Uterine Fibroid Symptoms with Relugolix Combination Therapy.

Short-term and long-term effects of tibolone in postmenopausal women.

See all (136)

Prognosis

Benign Metastasizing Leiomyoma: Is "Wait and Watch" Strategy Feasible?

Liu Y, Li D, Li X, Wang J, Wang J
Reprod Sci 2023 Dec;30(12):3568-3577. Epub 2023 Aug 2 doi: 10.1007/s43032-023-01314-9. PMID: 37531066

Indications for morcellation in gynecologic surgery.

Parker WH
Curr Opin Obstet Gynecol 2018 Feb;30(1):75-80. doi: 10.1097/GCO.0000000000000427. PMID: 29251677

Intercostal leiomyoma in a child: review of the literature.

Anastasiadis K, Kepertis C, Efstratiou I, Babatseva E, Spyridakis I
Pan Afr Med J 2017;28:283. Epub 2017 Nov 30 doi: 10.11604/pamj.2017.28.283.14274. PMID: 29942415 Free PMC Article

Sinonasal Leiomyoma With Estrogen Receptor Expression.

Kim JS, Shin JY, Kwon SH
J Craniofac Surg 2015 Sep;26(6):e500-2. doi: 10.1097/SCS.0000000000002011. PMID: 26355987

Acute leukemias: a dentist's perspective.

Pai A, Prasad S, Dyasanoor S
Minerva Stomatol 2012 May;61(5):233-8. PMID: 22576448

See all (70)

Clinical prediction guides

Clinical Utility of Diffusion-Weighted Imaging in Gynecological Imaging: Revisited.

Fujii S, Gonda T, Yunaga H
Invest Radiol 2024 Jan 1;59(1):78-91. Epub 2023 Jul 27 doi: 10.1097/RLI.0000000000001004. PMID: 37493356

LIBERTY randomized withdrawal study: relugolix combination therapy for heavy menstrual bleeding associated with uterine fibroids.

Al-Hendy A, Venturella R, Arjona Ferreira JC, Li Y, Soulban G, Wagman RB, Lukes AS
Am J Obstet Gynecol 2023 Dec;229(6):662.e1-662.e25. Epub 2023 Sep 2 doi: 10.1016/j.ajog.2023.08.030. PMID: 37666383

Long-term Relugolix Combination Therapy for Symptomatic Uterine Leiomyomas.

Vitamin D and female fertility.

Lerchbaum E, Rabe T
Curr Opin Obstet Gynecol 2014 Jun;26(3):145-50. doi: 10.1097/GCO.0000000000000065. PMID: 24717915

Current and future medical treatments for menometrorrhagia during the premenopause.

Bouchard P
Gynecol Endocrinol 2011 Dec;27 Suppl 1:1120-5. doi: 10.3109/09513590.2012.638754. PMID: 22182055

See all (61)

Recent systematic reviews

Endometrial Angiogenesis of Abnormal Uterine Bleeding and Infertility in Patients with Uterine Fibroids-A Systematic Review.

Don EE, Middelkoop MA, Hehenkamp WJK, Mijatovic V, Griffioen AW, Huirne JAF
Int J Mol Sci 2023 Apr 10;24(8) doi: 10.3390/ijms24087011. PMID: 37108180 Free PMC Article

Skull Base Leiomyomas and Angioleiomyomas: A Systematic Literature Review and an Uncommon Case Report.

Rincon-Torroella J, Snyder MH, Galaiya DJ, Morris M, Weingart JD, Stewart CM
World Neurosurg 2021 Oct;154:154-166.e1. Epub 2021 Jun 26 doi: 10.1016/j.wneu.2021.06.096. PMID: 34182177 Free PMC Article

Short-term and long-term effects of tibolone in postmenopausal women.

Pre-operative GnRH analogue therapy before hysterectomy or myomectomy for uterine fibroids.

Lethaby A, Vollenhoven B, Sowter M
Cochrane Database Syst Rev 2001;(2):CD000547. doi: 10.1002/14651858.CD000547. PMID: 11405968

Pre-operative GnRH analogue therapy before hysterectomy or myomectomy for uterine fibroids.

Lethaby A, Vollenhoven B, Sowter M
Cochrane Database Syst Rev 2000;(2):CD000547. doi: 10.1002/14651858.CD000547. PMID: 10796723

See all (8)