U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Portal cirrhosis

MedGen UID:
351440
•Concept ID:
C1622502
•
Disease or Syndrome
Synonyms: Laennec's cirrhosis; PC - Portal cirrhosis; Portal Cirrhosis
SNOMED CT: Portal cirrhosis (419728003); Laennec's cirrhosis (419728003); PC - Portal cirrhosis (419728003)

Definition

A nutritional cirrhosis that is characterized by an increase in connective tissue surrounding the portal spaces. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPortal cirrhosis

Professional guidelines

PubMed

Letter to the Editor: Emerging role of statin therapy in the prevention and management of cirrhosis, portal hypertension, and HCC.
Muñoz AE, Rodger EG
Hepatology 2024 Jul 1;80(1):E8. Epub 2024 Mar 11 doi: 10.1097/HEP.0000000000000846. PMID: 38466821
High risks adverse events associated with trastuzumab emtansine and trastuzumab deruxtecan for the treatment of HER2-positive/mutated malignancies: a pharmacovigilance study based on the FAERS database.
Ma P, Tian H, Shi Q, Liu R, Zhang Y, Qi X, Chen Y
Expert Opin Drug Saf 2023 Jul-Dec;22(8):685-696. Epub 2023 Apr 20 doi: 10.1080/14740338.2023.2204228. PMID: 37068935
Emerging role of statin therapy in the prevention and management of cirrhosis, portal hypertension, and HCC.
Sharpton SR, Loomba R
Hepatology 2023 Dec 1;78(6):1896-1906. Epub 2023 Jan 3 doi: 10.1097/HEP.0000000000000278. PMID: 37013380

Recent clinical studies

Etiology

RETROSPECTIVE ASSESSMENT OF CLINICAL-MORPHOLOGICAL CHANGES OF THE HEPATOBILIARY SYSTEM IN LIVER CIRRHOSIS OF THE CHORNOBYL NPP ACCIDENT CLEAN-UP WORKERS.
Sarkisova EO, Sushko VO, Chumak AA, Ovsyannikova LM, Nosach OV, Alyokhina SM, Shyiko TO
Probl Radiac Med Radiobiol 2019 Dec;24:465-479. doi: 10.33145/2304-8336-2019-24-465-479. PMID: 31841488
A non-linear mathematical model for the in vivo evaluation of the RES phagocytic function.
Bondareva IB, Parfenov AS
Medinfo 1995;8 Pt 2:1091. PMID: 8591376
Hepatocellular carcinoma in patients with acute intermittent porphyria.
Lithner F, Wetterberg L
Acta Med Scand 1984;215(3):271-4. doi: 10.1111/j.0954-6820.1984.tb05005.x. PMID: 6328897
Hepatic metastases and portal cirrhosis.
Goldstein MJ, Frable WJ, Sherlock P
Am J Med Sci 1966 Jul;252(1):26-30. doi: 10.1097/00000441-196607000-00004. PMID: 5941702
A note on the distribution of ABO blood groups in bronchiectasis and portal cirrhosis.
BILLINGTON BP
Australas Ann Med 1956 Feb;5(1):20-2. doi: 10.1111/imj.1956.5.1.20. PMID: 13315130

Diagnosis

ONE THOUSAND CASES OF PORTAL CIRRHOSIS OF THE LIVER. IMPLICATIONS OF ESOPHAGEAL VARICES AND THEIR MANAGEMENT.
BRICK IB, PALMER ED
Arch Intern Med 1964 Apr;113:501-11. doi: 10.1001/archinte.1964.00280100009003. PMID: 14109008
THE DIAGNOSIS OF PORTAL CIRRHOSIS.
VAKIL BJ, SHAH SJ, TULPULE TH, DESAI MG
J Assoc Physicians India 1963 Oct;11:795-808. PMID: 14071777
Portal cirrhosis and postnecrotic liver scarring.
HICKEY M
Ir J Med Sci 1956 Jul;(367):289-300. PMID: 13345524
Portal cirrhosis; diagnosis and management.
KONAR NR
J Indian Med Assoc 1955 Mar 1;24(11):425-8. PMID: 14367839
The diagnosis and treatment of portal cirrhosis of the liver.
KIEFER ED
Surg Clin North Am 1948 Jun;28:713-20. doi: 10.1016/s0039-6109(16)32446-x. PMID: 18861530

Therapy

RETROSPECTIVE ASSESSMENT OF CLINICAL-MORPHOLOGICAL CHANGES OF THE HEPATOBILIARY SYSTEM IN LIVER CIRRHOSIS OF THE CHORNOBYL NPP ACCIDENT CLEAN-UP WORKERS.
Sarkisova EO, Sushko VO, Chumak AA, Ovsyannikova LM, Nosach OV, Alyokhina SM, Shyiko TO
Probl Radiac Med Radiobiol 2019 Dec;24:465-479. doi: 10.33145/2304-8336-2019-24-465-479. PMID: 31841488
Severe liver injury due to phenelzine with unique hepatic deposition of extracellular material.
Bonkovsky HL, Blanchette PL, Schned AR
Am J Med 1986 Apr;80(4):689-92. doi: 10.1016/0002-9343(86)90826-0. PMID: 3963046
Juvenile Wilson disease: histologic and functional studies during penicillamine therapy.
Grand RJ, Vawter GF
J Pediatr 1975 Dec;87(6 Pt 2):1161-70. doi: 10.1016/s0022-3476(75)80131-4. PMID: 1185415
Assessment of aminopyrine metabolism in man by breath analysis after oral administration of 14C-aminopyrine. Effects of phenobarbital, disulfiram and portal cirrhosis.
Hepner GW, Vesell ES
N Engl J Med 1974 Dec 26;291(26):1384-8. doi: 10.1056/NEJM197412262912605. PMID: 4427643
Decompensated portal cirrhosis. Effects of large doses of phytonadione.
Ballard HS, Marcus AJ
Arch Intern Med 1966 Feb;117(2):182-6. doi: 10.1001/archinte.117.2.182. PMID: 5901549

Prognosis

ONE THOUSAND CASES OF PORTAL CIRRHOSIS OF THE LIVER. IMPLICATIONS OF ESOPHAGEAL VARICES AND THEIR MANAGEMENT.
BRICK IB, PALMER ED
Arch Intern Med 1964 Apr;113:501-11. doi: 10.1001/archinte.1964.00280100009003. PMID: 14109008
Portal cirrhosis. Causes of death in the era of portal decompression.
PALMER ED
Am J Surg 1960 Jun;99:906-7. doi: 10.1016/0002-9610(60)90483-9. PMID: 14429986
The low incidence of myocardial infarction in patients with portal cirrhosis of the liver: A review of 639 cases of cirrhosis of the liver from 17,731 autopsies.
HOWELL WL, MANION WC
Am Heart J 1960 Sep;60:341-4. doi: 10.1016/0002-8703(60)90192-7. PMID: 14403495
The incidence of portal cirrhosis and fatty metamorphosis in patients dying with diabetes mellitus.
JAQUES WE
N Engl J Med 1953 Sep 10;249(11):442-5. doi: 10.1056/NEJM195309102491104. PMID: 13087619
The prognosis of portal cirrhosis, an analysis of 62 cases.
MOSER RH, ROSENAK BD, PICKETT RD, McINTIRE CR
Gastroenterology 1951 May;18(1):86-92. PMID: 14840588

Clinical prediction guides

Observations on portal cirrhosis fatalities.
Palmer ED
Mil Med 1966 Jul;131(7):588-92. PMID: 4957680
Observations on portal cirrhosis of the liver; with special reference to the diagnosis of early and late cases.
KONAR NR
J Indian Med Assoc 1957 May 1;28(9):377-80. PMID: 13439180
Clinical observations on the severity of liver failure in portal cirrhosis.
RICKETTS WE, KIRSNER JB, PALMER WL
Gastroenterology 1950 Jun;15(2):245-56. PMID: 15427770
Pathologic observations in portal cirrhosis.
RICKETTS WE, LUSHBAUGH CC, KIRSNER JB, PALMER WL
Gastroenterology 1950 Apr;14(4):491-501. PMID: 15411944
Hepatitis and its sequelae, including the development of portal cirrhosis; observations on 100 cases.
KOSZALKA MF, LINDERT MC
Arch Intern Med (Chic) 1949 Nov;84(5):782-97. doi: 10.1001/archinte.1949.00230050118006. PMID: 15406857

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...