U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Paraneoplastic SPS is associated with breast cancer and other malignancies

MedGen UID:
350032
•Concept ID:
C1861471
•
Finding

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVParaneoplastic SPS is associated with breast cancer and other malignancies

Recent clinical studies

Etiology

Paraneoplastic stiff-person syndrome: passive transfer to rats by means of IgG antibodies to amphiphysin.
Sommer C, Weishaupt A, Brinkhoff J, Biko L, Wessig C, Gold R, Toyka KV
Lancet 2005 Apr 16-22;365(9468):1406-11. doi: 10.1016/S0140-6736(05)66376-3. PMID: 15836889

Diagnosis

Anti-amphiphysin positive stiff-person syndrome due to invasive ductal carcinoma in a male patient.
Connolly C, Cobain E, Hughes T
BMJ Case Rep 2021 May 24;14(5) doi: 10.1136/bcr-2020-237738. PMID: 34031061Free PMC Article
The horses are the first thought but one must not forget the zebras even if they are rare: Stiff person syndrome associated with malignant mesothelioma.
Koca I, Ucar M, Kalender ME, Alkan S
BMJ Case Rep 2014 Apr 7;2014 doi: 10.1136/bcr-2013-203455. PMID: 24711475Free PMC Article
Paraneoplastic stiff-person syndrome: passive transfer to rats by means of IgG antibodies to amphiphysin.
Sommer C, Weishaupt A, Brinkhoff J, Biko L, Wessig C, Gold R, Toyka KV
Lancet 2005 Apr 16-22;365(9468):1406-11. doi: 10.1016/S0140-6736(05)66376-3. PMID: 15836889

Therapy

Paraneoplastic stiff-person syndrome: passive transfer to rats by means of IgG antibodies to amphiphysin.
Sommer C, Weishaupt A, Brinkhoff J, Biko L, Wessig C, Gold R, Toyka KV
Lancet 2005 Apr 16-22;365(9468):1406-11. doi: 10.1016/S0140-6736(05)66376-3. PMID: 15836889

Supplemental Content

Table of contents

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...