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Childhood ependymoma

MedGen UID:
343609
Concept ID:
C1851584
Neoplastic Process
Synonyms: Adult intracranial ependymoma; Ependymoma, Familial; Familial ependymoma
 
Monarch Initiative: MONDO:0003478

Definition

An ependymoma that arises from the central nervous system and occurs during childhood. [from NCI]

Professional guidelines

PubMed

Hwang EI, Hanson D, Filbin MG, Mack SC
Neoplasia 2023 May;39:100895. Epub 2023 Mar 20 doi: 10.1016/j.neo.2023.100895. PMID: 36944298Free PMC Article
Liu AP, Shing MM, Yuen HL, Li CH, Ling SC, Luk CW, Ha SY, Li CK, Kwong DL, Chan GC
Pediatr Blood Cancer 2014 Apr;61(4):606-11. Epub 2013 Oct 26 doi: 10.1002/pbc.24820. PMID: 24167035
Grill J, Pascal C, Chantal K
Paediatr Drugs 2003;5(8):533-43. doi: 10.2165/00148581-200305080-00004. PMID: 12895136

Recent clinical studies

Etiology

Zhang C, Ostrom QT, Hansen HM, Gonzalez-Maya J, Hu D, Ziv E, Morimoto L, de Smith AJ, Muskens IS, Kline CN, Vaksman Z, Hakonarson H, Diskin SJ, Kruchko C, Barnholtz-Sloan JS, Ramaswamy V, Ali-Osman F, Bondy ML, Taylor MD, Metayer C, Wiemels JL, Walsh KM
Neuro Oncol 2020 Nov 26;22(11):1637-1646. doi: 10.1093/neuonc/noaa130. PMID: 32607579Free PMC Article
Marinoff AE, Ma C, Guo D, Snuderl M, Wright KD, Manley PE, Al-Sayegh H, Sinai CE, Ullrich NJ, Marcus K, Haas-Kogan D, Goumnerova L, London WB, Kieran MW, Chi SN, Fangusaro J, Bandopadhayay P
J Neurooncol 2017 Oct;135(1):201-211. Epub 2017 Jul 21 doi: 10.1007/s11060-017-2568-8. PMID: 28733870Free PMC Article
Merchant TE
J Clin Oncol 2017 Jul 20;35(21):2364-2369. Epub 2017 Jun 22 doi: 10.1200/JCO.2017.73.1265. PMID: 28640697
Liu AP, Shing MM, Yuen HL, Li CH, Ling SC, Luk CW, Ha SY, Li CK, Kwong DL, Chan GC
Pediatr Blood Cancer 2014 Apr;61(4):606-11. Epub 2013 Oct 26 doi: 10.1002/pbc.24820. PMID: 24167035
MacDonald SM, Safai S, Trofimov A, Wolfgang J, Fullerton B, Yeap BY, Bortfeld T, Tarbell NJ, Yock T
Int J Radiat Oncol Biol Phys 2008 Jul 15;71(4):979-86. Epub 2008 Mar 5 doi: 10.1016/j.ijrobp.2007.11.065. PMID: 18325681

Diagnosis

Myseros JS
Adv Tech Stand Neurosurg 2024;53:93-118. doi: 10.1007/978-3-031-67077-0_7. PMID: 39287805
Hwang EI, Hanson D, Filbin MG, Mack SC
Neoplasia 2023 May;39:100895. Epub 2023 Mar 20 doi: 10.1016/j.neo.2023.100895. PMID: 36944298Free PMC Article
Kalogeraki A, Tamiolakis D, Moustou E, Panayiotides I, Yannopoulos A, Vakis A, Katzilakis N, Stiakaki E
Acta Biomed 2021 May 12;92(2):e2021107. doi: 10.23750/abm.v92i2.9996. PMID: 33988164Free PMC Article
MacDonald SM, Safai S, Trofimov A, Wolfgang J, Fullerton B, Yeap BY, Bortfeld T, Tarbell NJ, Yock T
Int J Radiat Oncol Biol Phys 2008 Jul 15;71(4):979-86. Epub 2008 Mar 5 doi: 10.1016/j.ijrobp.2007.11.065. PMID: 18325681
Merchant TE
Oncology (Williston Park) 2002 May;16(5):629-42, 644; discussion 645-6, 648. PMID: 12108890

Therapy

Islam MM, Mirza SP
Drug Dev Res 2022 Nov;83(7):1505-1518. Epub 2022 Aug 28 doi: 10.1002/ddr.21984. PMID: 36031762
Merchant TE
J Clin Oncol 2017 Jul 20;35(21):2364-2369. Epub 2017 Jun 22 doi: 10.1200/JCO.2017.73.1265. PMID: 28640697
Di Pinto M, Conklin HM, Li C, Xiong X, Merchant TE
Int J Radiat Oncol Biol Phys 2010 Jul 15;77(4):1002-8. Epub 2009 Sep 23 doi: 10.1016/j.ijrobp.2009.06.003. PMID: 19783376Free PMC Article
Grill J, Pascal C, Chantal K
Paediatr Drugs 2003;5(8):533-43. doi: 10.2165/00148581-200305080-00004. PMID: 12895136
Merchant TE
Oncology (Williston Park) 2002 May;16(5):629-42, 644; discussion 645-6, 648. PMID: 12108890

Prognosis

Hwang EI, Hanson D, Filbin MG, Mack SC
Neoplasia 2023 May;39:100895. Epub 2023 Mar 20 doi: 10.1016/j.neo.2023.100895. PMID: 36944298Free PMC Article
Merchant TE
J Clin Oncol 2017 Jul 20;35(21):2364-2369. Epub 2017 Jun 22 doi: 10.1200/JCO.2017.73.1265. PMID: 28640697
Kim JH, Huang Y, Griffin AS, Rajappa P, Greenfield JP
Clin Transl Oncol 2013 Oct;15(10):759-65. Epub 2013 Apr 25 doi: 10.1007/s12094-013-1041-1. PMID: 23615979
Grill J, Pascal C, Chantal K
Paediatr Drugs 2003;5(8):533-43. doi: 10.2165/00148581-200305080-00004. PMID: 12895136
Merchant TE
Oncology (Williston Park) 2002 May;16(5):629-42, 644; discussion 645-6, 648. PMID: 12108890

Clinical prediction guides

Zhang C, Ostrom QT, Hansen HM, Gonzalez-Maya J, Hu D, Ziv E, Morimoto L, de Smith AJ, Muskens IS, Kline CN, Vaksman Z, Hakonarson H, Diskin SJ, Kruchko C, Barnholtz-Sloan JS, Ramaswamy V, Ali-Osman F, Bondy ML, Taylor MD, Metayer C, Wiemels JL, Walsh KM
Neuro Oncol 2020 Nov 26;22(11):1637-1646. doi: 10.1093/neuonc/noaa130. PMID: 32607579Free PMC Article
Panwalkar P, Clark J, Ramaswamy V, Hawes D, Yang F, Dunham C, Yip S, Hukin J, Sun Y, Schipper MJ, Chavez L, Margol A, Pekmezci M, Chung C, Banda A, Bayliss JM, Curry SJ, Santi M, Rodriguez FJ, Snuderl M, Karajannis MA, Saratsis AM, Horbinski CM, Carret AS, Wilson B, Johnston D, Lafay-Cousin L, Zelcer S, Eisenstat D, Silva M, Scheinemann K, Jabado N, McNeely PD, Kool M, Pfister SM, Taylor MD, Hawkins C, Korshunov A, Judkins AR, Venneti S
Acta Neuropathol 2017 Nov;134(5):705-714. Epub 2017 Jul 21 doi: 10.1007/s00401-017-1752-4. PMID: 28733933Free PMC Article
Liu AP, Shing MM, Yuen HL, Li CH, Ling SC, Luk CW, Ha SY, Li CK, Kwong DL, Chan GC
Pediatr Blood Cancer 2014 Apr;61(4):606-11. Epub 2013 Oct 26 doi: 10.1002/pbc.24820. PMID: 24167035
Kilday JP, Mitra B, Domerg C, Ward J, Andreiuolo F, Osteso-Ibanez T, Mauguen A, Varlet P, Le Deley MC, Lowe J, Ellison DW, Gilbertson RJ, Coyle B, Grill J, Grundy RG
Clin Cancer Res 2012 Apr 1;18(7):2001-11. Epub 2012 Feb 14 doi: 10.1158/1078-0432.CCR-11-2489. PMID: 22338015
Di Pinto M, Conklin HM, Li C, Xiong X, Merchant TE
Int J Radiat Oncol Biol Phys 2010 Jul 15;77(4):1002-8. Epub 2009 Sep 23 doi: 10.1016/j.ijrobp.2009.06.003. PMID: 19783376Free PMC Article

Recent systematic reviews

Grill J, Pascal C, Chantal K
Paediatr Drugs 2003;5(8):533-43. doi: 10.2165/00148581-200305080-00004. PMID: 12895136

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