U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Anterior clefting of vertebral bodies

MedGen UID:
337861
•Concept ID:
C1849579
•
Finding
HPO: HP:0009761

Definition

Anterior schisis (cleft or cleavage) of vertebral bodies. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnterior clefting of vertebral bodies

Conditions with this feature

Autosomal recessive multiple pterygium syndrome
MedGen UID:
82696
•Concept ID:
C0265261
•
Congenital Abnormality
Multiple pterygium syndromes comprise a group of multiple congenital anomaly disorders characterized by webbing (pterygia) of the neck, elbows, and/or knees and joint contractures (arthrogryposis) (Morgan et al., 2006). The multiple pterygium syndromes are phenotypically and genetically heterogeneous but are traditionally divided into prenatally lethal (253290) and nonlethal (Escobar) types.
See: Condition Record
Autosomal recessive multiple pterygium syndrome

Professional guidelines

PubMed

A novel bone cement screw system combined with vertebroplasty for the treatment of Kummell disease with bone deficiency at the vertebral anterior border: A minimum 3-year follow-up study.
Wang B, Wang Y, Zhang H, Yan L, Kong L, He S, Hao D
Clin Neurol Neurosurg 2021 Feb;201:106434. Epub 2020 Dec 17 doi: 10.1016/j.clineuro.2020.106434. PMID: 33370625
Percutaneous Kyphoplasty for the Treatment of Osteoporotic Vertebral Fractures With Intravertebral Fluid or Air: A Comparative Study.
Niu J, Song D, Zhou H, Meng Q, Meng B, Yang H
Clin Spine Surg 2017 Oct;30(8):367-373. doi: 10.1097/BSD.0000000000000262. PMID: 28937459

Recent clinical studies

Etiology

Risk factors for secondary fractures to percutaneous vertebroplasty for osteoporotic vertebral compression fractures: a systematic review.
Mao W, Dong F, Huang G, He P, Chen H, Qin S, Li A
J Orthop Surg Res 2021 Oct 30;16(1):644. doi: 10.1186/s13018-021-02722-w. PMID: 34717682Free PMC Article
Analysis of the curative effect of percutaneous kyphoplasty in the treatment of osteoporotic vertebral compression fracture with intravertebral clefts.
Li D, Zhou Y, Cui H, Kong L, Zhu W, Chai X, Zhuo H
Medicine (Baltimore) 2021 Jun 4;100(22):e25996. doi: 10.1097/MD.0000000000025996. PMID: 34087844Free PMC Article
The association between sarcopenia and osteoporotic vertebral compression refractures.
Wang WF, Lin CW, Xie CN, Liu HT, Zhu MY, Huang KL, Teng HL
Osteoporos Int 2019 Dec;30(12):2459-2467. Epub 2019 Sep 3 doi: 10.1007/s00198-019-05144-x. PMID: 31482304
Morphological changes of vertebral compression fracture with intra-vertebral cleft treated with percutaneous vertebroplasty.
Park SM, Park JW, Kim H, Kim HJ, Yeom JS, Lee CK, Chang BS
J Orthop Sci 2018 Mar;23(2):237-247. Epub 2017 Nov 23 doi: 10.1016/j.jos.2017.11.006. PMID: 29174421
Pseudoarthrosis of vertebral fracture: radiographic and characteristic clinical features and natural history.
Hashidate H, Kamimura M, Nakagawa H, Takahara K, Uchiyama S
J Orthop Sci 2006 Jan;11(1):28-33. doi: 10.1007/s00776-005-0967-8. PMID: 16437345

Diagnosis

Development and Internal Validation of Supervised Machine Learning Algorithm for Predicting the Risk of Recollapse Following Minimally Invasive Kyphoplasty in Osteoporotic Vertebral Compression Fractures.
Dong ST, Zhu J, Yang H, Huang G, Zhao C, Yuan B
Front Public Health 2022;10:874672. Epub 2022 May 2 doi: 10.3389/fpubh.2022.874672. PMID: 35586015Free PMC Article
Risk factors for secondary fractures to percutaneous vertebroplasty for osteoporotic vertebral compression fractures: a systematic review.
Mao W, Dong F, Huang G, He P, Chen H, Qin S, Li A
J Orthop Surg Res 2021 Oct 30;16(1):644. doi: 10.1186/s13018-021-02722-w. PMID: 34717682Free PMC Article
Multi-level sagittally cleft vertebrae: a case report and review of the literature.
Zeoli T, Iwanaga J, Dumont AS, Tubbs RS
Surg Radiol Anat 2021 Jan;43(1):127-130. Epub 2020 Jun 14 doi: 10.1007/s00276-020-02517-4. PMID: 32537674
Severe neurologic manifestations from cervical spine instability in spondylo-megaepiphyseal-metaphyseal dysplasia.
Simon M, Campos-Xavier AB, Mittaz-Crettol L, Valadares ER, Carvalho D, Speck-Martins CE, Nampoothiri S, Alanay Y, Mihci E, van Bever Y, Garcia-Segarra N, Cavalcanti D, Mortier G, Bonafé L, Superti-Furga A
Am J Med Genet C Semin Med Genet 2012 Aug 15;160C(3):230-7. Epub 2012 Jul 12 doi: 10.1002/ajmg.c.31339. PMID: 22791571
Pseudoarthrosis of vertebral fracture: radiographic and characteristic clinical features and natural history.
Hashidate H, Kamimura M, Nakagawa H, Takahara K, Uchiyama S
J Orthop Sci 2006 Jan;11(1):28-33. doi: 10.1007/s00776-005-0967-8. PMID: 16437345

Therapy

Risk factors for secondary vertebral compression fracture after percutaneous vertebral augmentation: a single-centre retrospective study.
Tang J, Wang S, Wang J, Wang X, Li T, Cheng L, Hu J, Xie W
J Orthop Surg Res 2024 Nov 27;19(1):797. doi: 10.1186/s13018-024-05290-x. PMID: 39593155Free PMC Article
Development and Internal Validation of Supervised Machine Learning Algorithm for Predicting the Risk of Recollapse Following Minimally Invasive Kyphoplasty in Osteoporotic Vertebral Compression Fractures.
Dong ST, Zhu J, Yang H, Huang G, Zhao C, Yuan B
Front Public Health 2022;10:874672. Epub 2022 May 2 doi: 10.3389/fpubh.2022.874672. PMID: 35586015Free PMC Article
CT-Guided Percutaneous Vertebroplasty for Vertebral Non-union Following Posterior Fixation: A Preliminary Retrospective Study.
Pavan LJ, Dalili D, Ranc C, Torre F, Clerk-Lamalice O, Burns R, Andreani O, Ranc PA, Bronsard N, Prestat A, Amoretti N
Cardiovasc Intervent Radiol 2022 May;45(5):687-695. Epub 2022 Jan 22 doi: 10.1007/s00270-021-03037-3. PMID: 35064285
Does the Relationship Between Bone Cement and the Intravertebral Cleft of Kummell Disease Affect the Efficacy of PKP?
Lv NN, Hou MZ, Zhou ZZ, Feng XX, Liu HJ, Shan FR, Li EH, Guan BY, He SJ, Liu MM
World Neurosurg 2022 Apr;160:e430-e435. Epub 2022 Jan 18 doi: 10.1016/j.wneu.2022.01.050. PMID: 35051635
Percutaneous vertebroplasty for cephalad vertebral fractures after instrumented lumbar fusion.
Seo JY, Ha KY, Son IN, Chang DG, Kim YH
J Spinal Disord Tech 2013 Apr;26(2):E58-64. doi: 10.1097/BSD.0b013e31826103f2. PMID: 23313947

Prognosis

Development and Internal Validation of Supervised Machine Learning Algorithm for Predicting the Risk of Recollapse Following Minimally Invasive Kyphoplasty in Osteoporotic Vertebral Compression Fractures.
Dong ST, Zhu J, Yang H, Huang G, Zhao C, Yuan B
Front Public Health 2022;10:874672. Epub 2022 May 2 doi: 10.3389/fpubh.2022.874672. PMID: 35586015Free PMC Article
A novel bone cement screw system combined with vertebroplasty for the treatment of Kummell disease with bone deficiency at the vertebral anterior border: A minimum 3-year follow-up study.
Wang B, Wang Y, Zhang H, Yan L, Kong L, He S, Hao D
Clin Neurol Neurosurg 2021 Feb;201:106434. Epub 2020 Dec 17 doi: 10.1016/j.clineuro.2020.106434. PMID: 33370625
The association between sarcopenia and osteoporotic vertebral compression refractures.
Wang WF, Lin CW, Xie CN, Liu HT, Zhu MY, Huang KL, Teng HL
Osteoporos Int 2019 Dec;30(12):2459-2467. Epub 2019 Sep 3 doi: 10.1007/s00198-019-05144-x. PMID: 31482304
Morphological changes of vertebral compression fracture with intra-vertebral cleft treated with percutaneous vertebroplasty.
Park SM, Park JW, Kim H, Kim HJ, Yeom JS, Lee CK, Chang BS
J Orthop Sci 2018 Mar;23(2):237-247. Epub 2017 Nov 23 doi: 10.1016/j.jos.2017.11.006. PMID: 29174421
Pseudoarthrosis of vertebral fracture: radiographic and characteristic clinical features and natural history.
Hashidate H, Kamimura M, Nakagawa H, Takahara K, Uchiyama S
J Orthop Sci 2006 Jan;11(1):28-33. doi: 10.1007/s00776-005-0967-8. PMID: 16437345

Clinical prediction guides

Does the Relationship Between Bone Cement and the Intravertebral Cleft of Kummell Disease Affect the Efficacy of PKP?
Lv NN, Hou MZ, Zhou ZZ, Feng XX, Liu HJ, Shan FR, Li EH, Guan BY, He SJ, Liu MM
World Neurosurg 2022 Apr;160:e430-e435. Epub 2022 Jan 18 doi: 10.1016/j.wneu.2022.01.050. PMID: 35051635
Analysis of the curative effect of percutaneous kyphoplasty in the treatment of osteoporotic vertebral compression fracture with intravertebral clefts.
Li D, Zhou Y, Cui H, Kong L, Zhu W, Chai X, Zhuo H
Medicine (Baltimore) 2021 Jun 4;100(22):e25996. doi: 10.1097/MD.0000000000025996. PMID: 34087844Free PMC Article
A novel bone cement screw system combined with vertebroplasty for the treatment of Kummell disease with bone deficiency at the vertebral anterior border: A minimum 3-year follow-up study.
Wang B, Wang Y, Zhang H, Yan L, Kong L, He S, Hao D
Clin Neurol Neurosurg 2021 Feb;201:106434. Epub 2020 Dec 17 doi: 10.1016/j.clineuro.2020.106434. PMID: 33370625
The association between sarcopenia and osteoporotic vertebral compression refractures.
Wang WF, Lin CW, Xie CN, Liu HT, Zhu MY, Huang KL, Teng HL
Osteoporos Int 2019 Dec;30(12):2459-2467. Epub 2019 Sep 3 doi: 10.1007/s00198-019-05144-x. PMID: 31482304
Morphological changes of vertebral compression fracture with intra-vertebral cleft treated with percutaneous vertebroplasty.
Park SM, Park JW, Kim H, Kim HJ, Yeom JS, Lee CK, Chang BS
J Orthop Sci 2018 Mar;23(2):237-247. Epub 2017 Nov 23 doi: 10.1016/j.jos.2017.11.006. PMID: 29174421

Recent systematic reviews

Risk factors for secondary fractures to percutaneous vertebroplasty for osteoporotic vertebral compression fractures: a systematic review.
Mao W, Dong F, Huang G, He P, Chen H, Qin S, Li A
J Orthop Surg Res 2021 Oct 30;16(1):644. doi: 10.1186/s13018-021-02722-w. PMID: 34717682Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...