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Increased risk of pancreatic cancer

MedGen UID:
330845
•Concept ID:
C1842408
•
Finding

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIncreased risk of pancreatic cancer

Professional guidelines

PubMed

Management of patients with increased risk for familial pancreatic cancer: updated recommendations from the International Cancer of the Pancreas Screening (CAPS) Consortium.
Goggins M, Overbeek KA, Brand R, Syngal S, Del Chiaro M, Bartsch DK, Bassi C, Carrato A, Farrell J, Fishman EK, Fockens P, Gress TM, van Hooft JE, Hruban RH, Kastrinos F, Klein A, Lennon AM, Lucas A, Park W, Rustgi A, Simeone D, Stoffel E, Vasen HFA, Cahen DL, Canto MI, Bruno M; International Cancer of the Pancreas Screening (CAPS) consortium
Gut 2020 Jan;69(1):7-17. Epub 2019 Oct 31 doi: 10.1136/gutjnl-2019-319352. PMID: 31672839Free PMC Article
Hereditary pancreatitis: dilemmas in differential diagnosis and therapeutic approach.
Mastoraki A, Tzortzopoulou A, Tsela S, Danias N, Sakorafas G, Smyrniotis V, Arkadopoulos N
J Gastrointest Cancer 2014 Mar;45(1):22-6. doi: 10.1007/s12029-013-9559-6. PMID: 24242859
Significant association between GSTT1 null genotype and susceptibility to pancreatic cancer.
Bu X, Zhao C
Mol Biol Rep 2013 Jul;40(7):4295-9. Epub 2013 May 30 doi: 10.1007/s11033-013-2516-4. PMID: 23720024

Recent clinical studies

Etiology

Pancreatic cancer: A review of epidemiology, trend, and risk factors.
Hu JX, Zhao CF, Chen WB, Liu QC, Li QW, Lin YY, Gao F
World J Gastroenterol 2021 Jul 21;27(27):4298-4321. doi: 10.3748/wjg.v27.i27.4298. PMID: 34366606Free PMC Article
Advances in the epidemiology of pancreatic cancer: Trends, risk factors, screening, and prognosis.
Cai J, Chen H, Lu M, Zhang Y, Lu B, You L, Zhang T, Dai M, Zhao Y
Cancer Lett 2021 Nov 1;520:1-11. Epub 2021 Jun 30 doi: 10.1016/j.canlet.2021.06.027. PMID: 34216688
Pancreatic cancer epidemiology: understanding the role of lifestyle and inherited risk factors.
Klein AP
Nat Rev Gastroenterol Hepatol 2021 Jul;18(7):493-502. Epub 2021 May 17 doi: 10.1038/s41575-021-00457-x. PMID: 34002083Free PMC Article
Pancreatic Cancer: Pathogenesis and Diagnosis.
Goral V
Asian Pac J Cancer Prev 2015;16(14):5619-24. doi: 10.7314/apjcp.2015.16.14.5619. PMID: 26320426
The epidemiology of pancreatitis and pancreatic cancer.
Yadav D, Lowenfels AB
Gastroenterology 2013 Jun;144(6):1252-61. doi: 10.1053/j.gastro.2013.01.068. PMID: 23622135Free PMC Article

Diagnosis

Pancreatic cancer: A review of epidemiology, trend, and risk factors.
Hu JX, Zhao CF, Chen WB, Liu QC, Li QW, Lin YY, Gao F
World J Gastroenterol 2021 Jul 21;27(27):4298-4321. doi: 10.3748/wjg.v27.i27.4298. PMID: 34366606Free PMC Article
Advances in the epidemiology of pancreatic cancer: Trends, risk factors, screening, and prognosis.
Cai J, Chen H, Lu M, Zhang Y, Lu B, You L, Zhang T, Dai M, Zhao Y
Cancer Lett 2021 Nov 1;520:1-11. Epub 2021 Jun 30 doi: 10.1016/j.canlet.2021.06.027. PMID: 34216688
Pancreatic cancer epidemiology: understanding the role of lifestyle and inherited risk factors.
Klein AP
Nat Rev Gastroenterol Hepatol 2021 Jul;18(7):493-502. Epub 2021 May 17 doi: 10.1038/s41575-021-00457-x. PMID: 34002083Free PMC Article
Management of patients with increased risk for familial pancreatic cancer: updated recommendations from the International Cancer of the Pancreas Screening (CAPS) Consortium.
Goggins M, Overbeek KA, Brand R, Syngal S, Del Chiaro M, Bartsch DK, Bassi C, Carrato A, Farrell J, Fishman EK, Fockens P, Gress TM, van Hooft JE, Hruban RH, Kastrinos F, Klein A, Lennon AM, Lucas A, Park W, Rustgi A, Simeone D, Stoffel E, Vasen HFA, Cahen DL, Canto MI, Bruno M; International Cancer of the Pancreas Screening (CAPS) consortium
Gut 2020 Jan;69(1):7-17. Epub 2019 Oct 31 doi: 10.1136/gutjnl-2019-319352. PMID: 31672839Free PMC Article
Pancreatic Cancer: Pathogenesis and Diagnosis.
Goral V
Asian Pac J Cancer Prev 2015;16(14):5619-24. doi: 10.7314/apjcp.2015.16.14.5619. PMID: 26320426

Therapy

Aspirin Use and Risk of Pancreatic Ductal Adenocarcinoma: A Large Case-Control Study.
Momayez Sanat Z, Masoudi S, Tabaeian SP, Jameh Shorani M, Soruri M, Pourshams A
Arch Iran Med 2023 Apr 1;26(4):181-185. doi: 10.34172/aim.2023.28. PMID: 38301077Free PMC Article
Pancreatitis and pancreatic cancer in patients with type 2 diabetes treated with glucagon-like peptide-1 receptor agonists: an updated meta-analysis of randomized controlled trials.
Nreu B, Dicembrini I, Tinti F, Mannucci E, Monami M
Minerva Endocrinol (Torino) 2023 Jun;48(2):206-213. Epub 2020 Jul 23 doi: 10.23736/S2724-6507.20.03219-8. PMID: 32720500
Effects of Berberine against Pancreatitis and Pancreatic Cancer.
Vlavcheski F, O'Neill EJ, Gagacev F, Tsiani E
Molecules 2022 Dec 6;27(23) doi: 10.3390/molecules27238630. PMID: 36500723Free PMC Article
Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma.
Grossberg AJ, Chu LC, Deig CR, Fishman EK, Hwang WL, Maitra A, Marks DL, Mehta A, Nabavizadeh N, Simeone DM, Weekes CD, Thomas CR Jr
CA Cancer J Clin 2020 Sep;70(5):375-403. Epub 2020 Jul 19 doi: 10.3322/caac.21626. PMID: 32683683Free PMC Article
The epidemiology of pancreatitis and pancreatic cancer.
Yadav D, Lowenfels AB
Gastroenterology 2013 Jun;144(6):1252-61. doi: 10.1053/j.gastro.2013.01.068. PMID: 23622135Free PMC Article

Prognosis

Pancreatic cancer: A review of epidemiology, trend, and risk factors.
Hu JX, Zhao CF, Chen WB, Liu QC, Li QW, Lin YY, Gao F
World J Gastroenterol 2021 Jul 21;27(27):4298-4321. doi: 10.3748/wjg.v27.i27.4298. PMID: 34366606Free PMC Article
Advances in the epidemiology of pancreatic cancer: Trends, risk factors, screening, and prognosis.
Cai J, Chen H, Lu M, Zhang Y, Lu B, You L, Zhang T, Dai M, Zhao Y
Cancer Lett 2021 Nov 1;520:1-11. Epub 2021 Jun 30 doi: 10.1016/j.canlet.2021.06.027. PMID: 34216688
Global Burden of 5 Major Types of Gastrointestinal Cancer.
Arnold M, Abnet CC, Neale RE, Vignat J, Giovannucci EL, McGlynn KA, Bray F
Gastroenterology 2020 Jul;159(1):335-349.e15. Epub 2020 Apr 2 doi: 10.1053/j.gastro.2020.02.068. PMID: 32247694Free PMC Article
Pancreatic Cancer: Pathogenesis and Diagnosis.
Goral V
Asian Pac J Cancer Prev 2015;16(14):5619-24. doi: 10.7314/apjcp.2015.16.14.5619. PMID: 26320426
The epidemiology of pancreatitis and pancreatic cancer.
Yadav D, Lowenfels AB
Gastroenterology 2013 Jun;144(6):1252-61. doi: 10.1053/j.gastro.2013.01.068. PMID: 23622135Free PMC Article

Clinical prediction guides

Aspirin Use and Risk of Pancreatic Ductal Adenocarcinoma: A Large Case-Control Study.
Momayez Sanat Z, Masoudi S, Tabaeian SP, Jameh Shorani M, Soruri M, Pourshams A
Arch Iran Med 2023 Apr 1;26(4):181-185. doi: 10.34172/aim.2023.28. PMID: 38301077Free PMC Article
Pancreatitis and pancreatic cancer in patients with type 2 diabetes treated with glucagon-like peptide-1 receptor agonists: an updated meta-analysis of randomized controlled trials.
Nreu B, Dicembrini I, Tinti F, Mannucci E, Monami M
Minerva Endocrinol (Torino) 2023 Jun;48(2):206-213. Epub 2020 Jul 23 doi: 10.23736/S2724-6507.20.03219-8. PMID: 32720500
Predicting Pancreatic Cancer in the UK Biobank Cohort Using Polygenic Risk Scores and Diabetes Mellitus.
Sharma S, Tapper WJ, Collins A, Hamady ZZR
Gastroenterology 2022 May;162(6):1665-1674.e2. Epub 2022 Jan 21 doi: 10.1053/j.gastro.2022.01.016. PMID: 35065983
Advances in the epidemiology of pancreatic cancer: Trends, risk factors, screening, and prognosis.
Cai J, Chen H, Lu M, Zhang Y, Lu B, You L, Zhang T, Dai M, Zhao Y
Cancer Lett 2021 Nov 1;520:1-11. Epub 2021 Jun 30 doi: 10.1016/j.canlet.2021.06.027. PMID: 34216688
Worldwide Burden of, Risk Factors for, and Trends in Pancreatic Cancer.
Huang J, Lok V, Ngai CH, Zhang L, Yuan J, Lao XQ, Ng K, Chong C, Zheng ZJ, Wong MCS
Gastroenterology 2021 Feb;160(3):744-754. Epub 2020 Oct 13 doi: 10.1053/j.gastro.2020.10.007. PMID: 33058868

Recent systematic reviews

Ultra-processed food consumption and cancer risk: A systematic review and meta-analysis.
Isaksen IM, Dankel SN
Clin Nutr 2023 Jun;42(6):919-928. Epub 2023 Mar 30 doi: 10.1016/j.clnu.2023.03.018. PMID: 37087831
Dietary sugar consumption and health: umbrella review.
Huang Y, Chen Z, Chen B, Li J, Yuan X, Li J, Wang W, Dai T, Chen H, Wang Y, Wang R, Wang P, Guo J, Dong Q, Liu C, Wei Q, Cao D, Liu L
BMJ 2023 Apr 5;381:e071609. doi: 10.1136/bmj-2022-071609. PMID: 37019448Free PMC Article
Type 2 Diabetes and Cancer: An Umbrella Review of Observational and Mendelian Randomization Studies.
Pearson-Stuttard J, Papadimitriou N, Markozannes G, Cividini S, Kakourou A, Gill D, Rizos EC, Monori G, Ward HA, Kyrgiou M, Gunter MJ, Tsilidis KK
Cancer Epidemiol Biomarkers Prev 2021 Jun;30(6):1218-1228. Epub 2021 Mar 18 doi: 10.1158/1055-9965.EPI-20-1245. PMID: 33737302Free PMC Article
Cardiovascular, mortality, and kidney outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: a systematic review and meta-analysis of cardiovascular outcome trials.
Kristensen SL, Rørth R, Jhund PS, Docherty KF, Sattar N, Preiss D, Køber L, Petrie MC, McMurray JJV
Lancet Diabetes Endocrinol 2019 Oct;7(10):776-785. Epub 2019 Aug 14 doi: 10.1016/S2213-8587(19)30249-9. PMID: 31422062
Metabolic syndrome and risk of cancer: a systematic review and meta-analysis.
Esposito K, Chiodini P, Colao A, Lenzi A, Giugliano D
Diabetes Care 2012 Nov;35(11):2402-11. doi: 10.2337/dc12-0336. PMID: 23093685Free PMC Article

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