U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Gallbladder Papillary Adenoma

MedGen UID:
313218
•Concept ID:
C1708176
•
Neoplastic Process

Definition

An adenoma that arises from the gallbladder. It is characterized by the presence of a papillary growth pattern. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGallbladder Papillary Adenoma

Professional guidelines

PubMed

Surgical and non-surgical interventions for primary and salvage treatment of growth hormone-secreting pituitary adenomas in adults.
Caulley L, Quinn JG, Doyle MA, Alkherayf F, Metzendorf MI, Kilty S, Hunink MGM
Cochrane Database Syst Rev 2024 Feb 6;2(2):CD013561. doi: 10.1002/14651858.CD013561.pub2. PMID: 38318883Free PMC Article
Dysplasia and carcinoma of the gallbladder: pathological evaluation, sampling, differential diagnosis and clinical implications.
Roa JC, Basturk O, Adsay V
Histopathology 2021 Jul;79(1):2-19. Epub 2021 May 6 doi: 10.1111/his.14360. PMID: 33629395
The management of gallbladder polyps.
Valibouze C, El Amrani M, Truant S, Leroy C, Millet G, Pruvot FR, Zerbib P
J Visc Surg 2020 Oct;157(5):410-417. Epub 2020 May 27 doi: 10.1016/j.jviscsurg.2020.04.008. PMID: 32473822

Recent clinical studies

Etiology

Ultrasonographic Appearance of Gallbladder Neoplasia in 14 Dogs and 1 Cat.
MacLeod AN, Reichle JK, Szabo D, Cohen EB, Artiles C, Fulkerson CV, Kurihara M, Mattoon J
Vet Radiol Ultrasound 2023 May;64(3):537-545. Epub 2023 Mar 3 doi: 10.1111/vru.13227. PMID: 36867397
Acute cholecystitis associated with a novel integrated biliary stent and nasobiliary drainage catheter system.
Yamamoto K, Hirakawa N, Itoi T
J Hepatobiliary Pancreat Sci 2023 May;30(5):e28-e30. Epub 2022 Sep 12 doi: 10.1002/jhbp.1234. PMID: 36050812
Molecular Diagnostics in the Neoplasms of the Pancreas, Liver, Gallbladder, and Extrahepatic Biliary Tract: 2018 Update.
Zhang L, Bluth MH, Bhalla A
Clin Lab Med 2018 Jun;38(2):367-384. doi: 10.1016/j.cll.2018.03.003. PMID: 29776636
Biliary carcinogenesis in pancreaticobiliary maljunction.
Kamisawa T, Kuruma S, Chiba K, Tabata T, Koizumi S, Kikuyama M
J Gastroenterol 2017 Feb;52(2):158-163. Epub 2016 Oct 4 doi: 10.1007/s00535-016-1268-z. PMID: 27704265
Unresectable malignant biliary obstruction: treatment by self-expandable biliary endoprostheses.
Glättli A, Stain SC, Baer HU, Schweizer W, Triller J, Blumgart LH
HPB Surg 1993;6(3):175-84. doi: 10.1155/1993/78590. PMID: 7683908Free PMC Article

Diagnosis

Ultrasonographic Appearance of Gallbladder Neoplasia in 14 Dogs and 1 Cat.
MacLeod AN, Reichle JK, Szabo D, Cohen EB, Artiles C, Fulkerson CV, Kurihara M, Mattoon J
Vet Radiol Ultrasound 2023 May;64(3):537-545. Epub 2023 Mar 3 doi: 10.1111/vru.13227. PMID: 36867397
Patient-derived organoids for personalized gallbladder cancer modelling and drug screening.
Yuan B, Zhao X, Wang X, Liu E, Liu C, Zong Y, Jiang Y, Hou M, Chen Y, Chen L, Zhang Y, Wang H, Fu J
Clin Transl Med 2022 Jan;12(1):e678. doi: 10.1002/ctm2.678. PMID: 35075805Free PMC Article
Dysplasia and carcinoma of the gallbladder: pathological evaluation, sampling, differential diagnosis and clinical implications.
Roa JC, Basturk O, Adsay V
Histopathology 2021 Jul;79(1):2-19. Epub 2021 May 6 doi: 10.1111/his.14360. PMID: 33629395
Benign gallbladder diseases: Imaging techniques and tips for differentiating with malignant gallbladder diseases.
Yu MH, Kim YJ, Park HS, Jung SI
World J Gastroenterol 2020 Jun 14;26(22):2967-2986. doi: 10.3748/wjg.v26.i22.2967. PMID: 32587442Free PMC Article
Cholangiocarcinoma.
Kaude J, Rian R
Radiology 1971 Sep;100(3):573-80. doi: 10.1148/100.3.573. PMID: 4327847

Therapy

Key CT and MRI findings of drug-associated hepatobiliary and pancreatic disorders.
Ichikawa S, Goshima S
Jpn J Radiol 2024 Mar;42(3):235-245. Epub 2023 Nov 6 doi: 10.1007/s11604-023-01505-z. PMID: 37926781Free PMC Article
Acute cholecystitis associated with a novel integrated biliary stent and nasobiliary drainage catheter system.
Yamamoto K, Hirakawa N, Itoi T
J Hepatobiliary Pancreat Sci 2023 May;30(5):e28-e30. Epub 2022 Sep 12 doi: 10.1002/jhbp.1234. PMID: 36050812
Gallbladder tubulovillous adenoma in a patient with liver fluke infection.
Cheng Y, Jia Q, Xiong X, Ye H, Cheng N
J Gastrointestin Liver Dis 2013 Dec;22(4):374. PMID: 24369316
Unresectable malignant biliary obstruction: treatment by self-expandable biliary endoprostheses.
Glättli A, Stain SC, Baer HU, Schweizer W, Triller J, Blumgart LH
HPB Surg 1993;6(3):175-84. doi: 10.1155/1993/78590. PMID: 7683908Free PMC Article
Which birth control pill should be prescribed?
Speroff L
Fertil Steril 1976 Sep;27(9):997-1008. doi: 10.1016/s0015-0282(16)42068-6. PMID: 786747

Prognosis

Comprehensive single-cell analysis deciphered microenvironmental dynamics and immune regulator olfactomedin 4 in pathogenesis of gallbladder cancer.
He H, Chen S, Yu Y, Fan Z, Qian Y, Dong Y, Song Y, Zhong C, Sun X, Cao Q, Li S, Huang W, Li W, Zhuang M, Yang J, Wang X, Wang J, Wu D, Wang H, Wen W
Gut 2024 Aug 8;73(9):1529-1542. doi: 10.1136/gutjnl-2023-331773. PMID: 38719336Free PMC Article
Ultrasonographic Appearance of Gallbladder Neoplasia in 14 Dogs and 1 Cat.
MacLeod AN, Reichle JK, Szabo D, Cohen EB, Artiles C, Fulkerson CV, Kurihara M, Mattoon J
Vet Radiol Ultrasound 2023 May;64(3):537-545. Epub 2023 Mar 3 doi: 10.1111/vru.13227. PMID: 36867397
Patient-derived organoids for personalized gallbladder cancer modelling and drug screening.
Yuan B, Zhao X, Wang X, Liu E, Liu C, Zong Y, Jiang Y, Hou M, Chen Y, Chen L, Zhang Y, Wang H, Fu J
Clin Transl Med 2022 Jan;12(1):e678. doi: 10.1002/ctm2.678. PMID: 35075805Free PMC Article
Traditional serrated adenomas of the upper digestive tract.
Rubio CA
J Clin Pathol 2016 Jan;69(1):1-5. Epub 2015 Oct 14 doi: 10.1136/jclinpath-2015-203258. PMID: 26468393Free PMC Article
Intracholecystic papillary-tubular neoplasms (ICPN) of the gallbladder (neoplastic polyps, adenomas, and papillary neoplasms that are ≥1.0 cm): clinicopathologic and immunohistochemical analysis of 123 cases.
Adsay V, Jang KT, Roa JC, Dursun N, Ohike N, Bagci P, Basturk O, Bandyopadhyay S, Cheng JD, Sarmiento JM, Escalona OT, Goodman M, Kong SY, Terry P
Am J Surg Pathol 2012 Sep;36(9):1279-301. doi: 10.1097/PAS.0b013e318262787c. PMID: 22895264

Clinical prediction guides

Risk prediction and analysis of gallbladder polyps with deep neural network.
Yuan K, Zhang X, Yang Q, Deng X, Deng Z, Liao X, Si W
Comput Assist Surg (Abingdon) 2024 Dec;29(1):2331774. Epub 2024 Mar 23 doi: 10.1080/24699322.2024.2331774. PMID: 38520294
Preoperative prediction model for non-neoplastic and benign neoplastic polyps of the gallbladder.
Wang Y, Peng J, Liu K, Sun P, Ma Y, Zeng J, Jiang Y, Tan B, Cao J, Hu W
Eur J Surg Oncol 2024 Feb;50(2):107930. Epub 2023 Dec 27 doi: 10.1016/j.ejso.2023.107930. PMID: 38159390
Value of prediction model in distinguishing gallbladder adenoma from cholesterol polyp.
Liu J, Qian Y, Yang F, Huang S, Chen G, Yu J, Jiang S, Huang G
J Gastroenterol Hepatol 2022 Oct;37(10):1893-1900. Epub 2022 Jul 22 doi: 10.1111/jgh.15928. PMID: 35750491
Interpreting body MRI cases: classic findings in abdominal MRI.
Kania L, Guglielmo F, Mitchell D
Abdom Radiol (NY) 2018 Oct;43(10):2790-2808. doi: 10.1007/s00261-018-1551-y. PMID: 29594465
Relationship between intensity of Opisthorchis viverrini infection and hepatobiliary disease detected by ultrasonography.
Mairiang E, Elkins DB, Mairiang P, Chaiyakum J, Chamadol N, Loapaiboon V, Posri S, Sithithaworn P, Haswell-Elkins M
J Gastroenterol Hepatol 1992 Jan-Feb;7(1):17-21. doi: 10.1111/j.1440-1746.1992.tb00928.x. PMID: 1311966

Recent systematic reviews

Diagnostic accuracy of magnifying chromoendoscopy in the assessment of tumor invasion depth in early colorectal cancer: a systematic review and meta-analysis.
Huang Y, Yang Z, Yao Y, Liu G, Chen R
Tech Coloproctol 2023 Dec;27(12):1155-1167. Epub 2023 Jul 20 doi: 10.1007/s10151-023-02833-y. PMID: 37474693
Is contrast enhanced ultrasonography an accurate way to diagnose gallbladder adenoma? A systematic review and meta-analysis.
Behzadmehr R, Salarzaei M
J Med Imaging Radiat Sci 2021 Mar;52(1):127-136. Epub 2020 Oct 29 doi: 10.1016/j.jmir.2020.09.014. PMID: 33129756
Transabdominal ultrasound and endoscopic ultrasound for diagnosis of gallbladder polyps.
Wennmacker SZ, Lamberts MP, Di Martino M, Drenth JP, Gurusamy KS, van Laarhoven CJ
Cochrane Database Syst Rev 2018 Aug 15;8(8):CD012233. doi: 10.1002/14651858.CD012233.pub2. PMID: 30109701Free PMC Article
Can gallbladder polyps predict colorectal adenoma or even neoplasia? A systematic review.
Stergios K, Damaskos C, Frountzas M, Nikiteas N, Lalude O
Int J Surg 2016 Sep;33 Pt A:23-7. Epub 2016 Jul 25 doi: 10.1016/j.ijsu.2016.06.048. PMID: 27461907
Growth rate and malignant potential of small gallbladder polyps--systematic review of evidence.
Wiles R, Varadpande M, Muly S, Webb J
Surgeon 2014 Aug;12(4):221-6. Epub 2014 Feb 4 doi: 10.1016/j.surge.2014.01.003. PMID: 24502936

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...