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Lung germ cell tumor

MedGen UID:
310947
•Concept ID:
C1708771
•
Neoplastic Process
Synonyms: Lung Germ Cell Neoplasm; lung germ cell neoplasm; Lung Germ Cell Tumor; lung germ cell tumor
 
Monarch Initiative: MONDO:0037105

Definition

A germ cell tumor that arises from the lung. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLung germ cell tumor

Professional guidelines

PubMed

Update on the clinical management of multiple endocrine neoplasia type 1.
Pieterman CRC, Valk GD
Clin Endocrinol (Oxf) 2022 Oct;97(4):409-423. Epub 2022 Apr 1 doi: 10.1111/cen.14727. PMID: 35319130Free PMC Article
Lung and thymic carcinoids: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up(☆).
Baudin E, Caplin M, Garcia-Carbonero R, Fazio N, Ferolla P, Filosso PL, Frilling A, de Herder WW, Hörsch D, Knigge U, Korse CM, Lim E, Lombard-Bohas C, Pavel M, Scoazec JY, Sundin A, Berruti A; ESMO Guidelines Committee. Electronic address: [email protected]
Ann Oncol 2021 Apr;32(4):439-451. Epub 2021 Jan 19 doi: 10.1016/j.annonc.2021.01.003. PMID: 33482246
Management of toxicities of immune checkpoint inhibitors.
Spain L, Diem S, Larkin J
Cancer Treat Rev 2016 Mar;44:51-60. Epub 2016 Feb 6 doi: 10.1016/j.ctrv.2016.02.001. PMID: 26874776

Recent clinical studies

Etiology

Updates on lung neuroendocrine neoplasm classification.
Vocino Trucco G, Righi L, Volante M, Papotti M
Histopathology 2024 Jan;84(1):67-85. Epub 2023 Oct 4 doi: 10.1111/his.15058. PMID: 37794655
Utility of polygenic risk scores in UK cancer screening: a modelling analysis.
Huntley C, Torr B, Sud A, Rowlands CF, Way R, Snape K, Hanson H, Swanton C, Broggio J, Lucassen A, McCartney M, Houlston RS, Hingorani AD, Jones ME, Turnbull C
Lancet Oncol 2023 Jun;24(6):658-668. Epub 2023 May 10 doi: 10.1016/S1470-2045(23)00156-0. PMID: 37178708
Current Management of Carcinoid Tumor: When Is a Wedge Enough?
Collins ML, Okusanya O
Thorac Surg Clin 2023 May;33(2):159-164. Epub 2023 Feb 26 doi: 10.1016/j.thorsurg.2023.01.008. PMID: 37045485
Neuroendocrine neoplasms of the lung and gastrointestinal system: convergent biology and a path to better therapies.
Kawasaki K, Rekhtman N, Quintanal-Villalonga Á, Rudin CM
Nat Rev Clin Oncol 2023 Jan;20(1):16-32. Epub 2022 Oct 28 doi: 10.1038/s41571-022-00696-0. PMID: 36307533
Pulmonary Metastasectomy for Germ Cell Tumors.
Farazdaghi A, Vaughn DJ, Singhal S
Ann Thorac Cardiovasc Surg 2019 Dec 20;25(6):289-295. Epub 2019 Nov 13 doi: 10.5761/atcs.ra.19-00070. PMID: 31723083Free PMC Article

Diagnosis

Cannonball Pulmonary Lesions.
Wittrock E, Hagner MD
N Engl J Med 2024 Sep 5;391(9):844. Epub 2024 Aug 31 doi: 10.1056/NEJMicm2403364. PMID: 39216098
Updates on lung neuroendocrine neoplasm classification.
Vocino Trucco G, Righi L, Volante M, Papotti M
Histopathology 2024 Jan;84(1):67-85. Epub 2023 Oct 4 doi: 10.1111/his.15058. PMID: 37794655
Organ-Specificity of Breast Cancer Metastasis.
Ibragimova MK, Tsyganov MM, Kravtsova EA, Tsydenova IA, Litviakov NV
Int J Mol Sci 2023 Oct 26;24(21) doi: 10.3390/ijms242115625. PMID: 37958607Free PMC Article
Nipple shadows.
Kim SS, Lee HJ
Eur J Intern Med 2019 Jun;64:e1-e2. Epub 2018 Dec 23 doi: 10.1016/j.ejim.2018.12.008. PMID: 30587452
Neoplastic Pericardial Disease.
Maleszewski JJ, Anavekar NS
Cardiol Clin 2017 Nov;35(4):589-600. Epub 2017 Sep 6 doi: 10.1016/j.ccl.2017.07.011. PMID: 29025549

Therapy

Utility of polygenic risk scores in UK cancer screening: a modelling analysis.
Huntley C, Torr B, Sud A, Rowlands CF, Way R, Snape K, Hanson H, Swanton C, Broggio J, Lucassen A, McCartney M, Houlston RS, Hingorani AD, Jones ME, Turnbull C
Lancet Oncol 2023 Jun;24(6):658-668. Epub 2023 May 10 doi: 10.1016/S1470-2045(23)00156-0. PMID: 37178708
Phase I trial of the DLL3/CD3 bispecific T-cell engager BI 764532 in DLL3-positive small-cell lung cancer and neuroendocrine carcinomas.
Wermke M, Felip E, Gambardella V, Kuboki Y, Morgensztern D, Hamed ZO, Liu M, Studeny M, Owonikoko TK
Future Oncol 2022 Aug;18(24):2639-2649. Epub 2022 Jul 11 doi: 10.2217/fon-2022-0196. PMID: 35815644
Hypertensive Heartbreak.
Lau ES, Vaidya A, Schaefer IM, Scirica BM
N Engl J Med 2021 May 27;384(21):e80. doi: 10.1056/NEJMimc2031595. PMID: 34042392
Pulmonary Metastasectomy for Germ Cell Tumors.
Farazdaghi A, Vaughn DJ, Singhal S
Ann Thorac Cardiovasc Surg 2019 Dec 20;25(6):289-295. Epub 2019 Nov 13 doi: 10.5761/atcs.ra.19-00070. PMID: 31723083Free PMC Article
Endobronchial Embryonal Carcinoma.
Moreira-Meyer A, Bautista-Herrera D, Hernández-González M, Navarro-Reynoso F, Cicero-Sabido R, Núñez-Pérez-Redondo C
J Bronchology Interv Pulmonol 2017 Apr;24(2):148-152. doi: 10.1097/LBR.0000000000000315. PMID: 28323728

Prognosis

Updates on lung neuroendocrine neoplasm classification.
Vocino Trucco G, Righi L, Volante M, Papotti M
Histopathology 2024 Jan;84(1):67-85. Epub 2023 Oct 4 doi: 10.1111/his.15058. PMID: 37794655
Hypertensive Heartbreak.
Lau ES, Vaidya A, Schaefer IM, Scirica BM
N Engl J Med 2021 May 27;384(21):e80. doi: 10.1056/NEJMimc2031595. PMID: 34042392
Lung and thymic carcinoids: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up(☆).
Baudin E, Caplin M, Garcia-Carbonero R, Fazio N, Ferolla P, Filosso PL, Frilling A, de Herder WW, Hörsch D, Knigge U, Korse CM, Lim E, Lombard-Bohas C, Pavel M, Scoazec JY, Sundin A, Berruti A; ESMO Guidelines Committee. Electronic address: [email protected]
Ann Oncol 2021 Apr;32(4):439-451. Epub 2021 Jan 19 doi: 10.1016/j.annonc.2021.01.003. PMID: 33482246
Surgical management of lung metastases.
Patrini D, Panagiotopoulos N, Lawrence D, Scarci M
Br J Hosp Med (Lond) 2017 Apr 2;78(4):192-198. doi: 10.12968/hmed.2017.78.4.192. PMID: 28398890
Epidemiology of neuroendocrine tumours.
Taal BG, Visser O
Neuroendocrinology 2004;80 Suppl 1:3-7. doi: 10.1159/000080731. PMID: 15477707

Clinical prediction guides

Utility of polygenic risk scores in UK cancer screening: a modelling analysis.
Huntley C, Torr B, Sud A, Rowlands CF, Way R, Snape K, Hanson H, Swanton C, Broggio J, Lucassen A, McCartney M, Houlston RS, Hingorani AD, Jones ME, Turnbull C
Lancet Oncol 2023 Jun;24(6):658-668. Epub 2023 May 10 doi: 10.1016/S1470-2045(23)00156-0. PMID: 37178708
Overview of the 2022 WHO Classification of Paragangliomas and Pheochromocytomas.
Mete O, Asa SL, Gill AJ, Kimura N, de Krijger RR, Tischler A
Endocr Pathol 2022 Mar;33(1):90-114. Epub 2022 Mar 13 doi: 10.1007/s12022-022-09704-6. PMID: 35285002
Lung neuroendocrine neoplasms: recent progress and persistent challenges.
Rekhtman N
Mod Pathol 2022 Jan;35(Suppl 1):36-50. Epub 2021 Oct 18 doi: 10.1038/s41379-021-00943-2. PMID: 34663914Free PMC Article
Neuroendocrine neoplasms of the lung: Concepts and terminology.
Wick MR, Marchevsky AM
Semin Diagn Pathol 2015 Nov;32(6):445-55. Epub 2015 Sep 25 doi: 10.1053/j.semdp.2015.09.012. PMID: 26500079
Medullary Thyroid Carcinoma: Imaging.
Delorme S, Raue F
Recent Results Cancer Res 2015;204:91-116. doi: 10.1007/978-3-319-22542-5_4. PMID: 26494385

Recent systematic reviews

Encephalitis Induced by Immune Checkpoint Inhibitors: A Systematic Review.
Velasco R, Villagrán M, Jové M, Simó M, Vilariño N, Alemany M, Palmero R, Martínez-Villacampa MM, Nadal E, Bruna J
JAMA Neurol 2021 Jul 1;78(7):864-873. doi: 10.1001/jamaneurol.2021.0249. PMID: 33720308
Commonwealth Neuroendocrine Tumour Research Collaboration and the North American Neuroendocrine Tumor Society Guidelines for the Diagnosis and Management of Patients With Lung Neuroendocrine Tumors: An International Collaborative Endorsement and Update of the 2015 European Neuroendocrine Tumor Society Expert Consensus Guidelines.
Singh S, Bergsland EK, Card CM, Hope TA, Kunz PL, Laidley DT, Lawrence B, Leyden S, Metz DC, Michael M, Modahl LE, Myrehaug S, Padda SK, Pommier RF, Ramirez RA, Soulen M, Strosberg J, Sung A, Thawer A, Wei B, Xu B, Segelov E
J Thorac Oncol 2020 Oct;15(10):1577-1598. Epub 2020 Jul 11 doi: 10.1016/j.jtho.2020.06.021. PMID: 32663527
Association Between Marijuana Use and Risk of Cancer: A Systematic Review and Meta-analysis.
Ghasemiesfe M, Barrow B, Leonard S, Keyhani S, Korenstein D
JAMA Netw Open 2019 Nov 1;2(11):e1916318. doi: 10.1001/jamanetworkopen.2019.16318. PMID: 31774524Free PMC Article
Incidence of Programmed Cell Death 1 Inhibitor-Related Pneumonitis in Patients With Advanced Cancer: A Systematic Review and Meta-analysis.
Nishino M, Giobbie-Hurder A, Hatabu H, Ramaiya NH, Hodi FS
JAMA Oncol 2016 Dec 1;2(12):1607-1616. doi: 10.1001/jamaoncol.2016.2453. PMID: 27540850
Pulmonary neuroendocrine (carcinoid) tumors: European Neuroendocrine Tumor Society expert consensus and recommendations for best practice for typical and atypical pulmonary carcinoids.
Caplin ME, Baudin E, Ferolla P, Filosso P, Garcia-Yuste M, Lim E, Oberg K, Pelosi G, Perren A, Rossi RE, Travis WD; ENETS consensus conference participants
Ann Oncol 2015 Aug;26(8):1604-20. Epub 2015 Feb 2 doi: 10.1093/annonc/mdv041. PMID: 25646366

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