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Pericardial Solitary Fibrous Tumor

MedGen UID:
310934
•Concept ID:
C1708716
•
Neoplastic Process
Synonym: Pericardial Fibroma

Definition

A localized neoplasm of probable fibroblastic derivation, that arises from the pericardium. It is characterized by the presence of round to spindle-shaped cells, hylanized stroma formation, thin-walled branching blood vessels, and thin bands of collagen. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPericardial Solitary Fibrous Tumor

Recent clinical studies

Etiology

Endobronchial solitary fibrous tumors: An enigma for diagnosis.
Ramalhosa F, Pezzuto F, Fortarezza F, Canu G, Biondini D, Faccioli E, Polverosi R, Giraudo C, Calabrese F
Pathol Res Pract 2024 Apr;256:155240. Epub 2024 Mar 4 doi: 10.1016/j.prp.2024.155240. PMID: 38492357
Ectopic thymoma: Retrospective analysis of eight cases with clinical features and computed tomography findings.
Zhou Q, Han L, Ke X, Zhou J
Clin Imaging 2020 Apr;60(2):153-159. Epub 2019 Dec 6 doi: 10.1016/j.clinimag.2019.10.017. PMID: 31927170
The clinicopathological significance of NAB2-STAT6 gene fusions in 52 cases of intrathoracic solitary fibrous tumors.
Huang SC, Li CF, Kao YC, Chuang IC, Tai HC, Tsai JW, Yu SC, Huang HY, Lan J, Yen SL, Lin PC, Chen TC
Cancer Med 2016 Feb;5(2):159-68. Epub 2015 Dec 21 doi: 10.1002/cam4.572. PMID: 26686340Free PMC Article
Gigantic solitary fibrous tumour of extra-peritoneal space. A case report and review of the literature.
Guzel T, Dąbrowski B, Mazurkiewicz M, Makiewicz M, Krasnoębski IW
Pol Przegl Chir 2014 Jul;86(7):337-40. doi: 10.2478/pjs-2014-0059. PMID: 25222582
Solitary fibrous tumors of the pleura: clinical characteristics, surgical treatment and outcome.
Magdeleinat P, Alifano M, Petino A, Le Rochais JP, Dulmet E, Galateau F, Icard P, Regnard JF
Eur J Cardiothorac Surg 2002 Jun;21(6):1087-93. doi: 10.1016/s1010-7940(02)00099-4. PMID: 12048090

Diagnosis

An unusual location of solitary fibrous tumor in heart-A case report and review of literature.
Fain K, Parmar K, Sharma M, Horn R, Sethi P
Cancer Rep (Hoboken) 2022 Nov;5(11):e1698. Epub 2022 Aug 30 doi: 10.1002/cnr2.1698. PMID: 36041816Free PMC Article
The pleura and the endocrine system.
Sorino C, Negri S, Spanevello A, Feller-Kopman D
Eur J Intern Med 2020 Feb;72:34-37. Epub 2020 Jan 7 doi: 10.1016/j.ejim.2019.12.034. PMID: 31918926
Pericardial malignant solitary fibrous tumour with right atrial invasion - a case report and literature review.
Zhang LP, Zhang L, Wang G, Adhikari BK, Liu Q, Zhang W
J Int Med Res 2019 Jun;47(6):2716-2722. Epub 2019 Apr 28 doi: 10.1177/0300060519843734. PMID: 31032675Free PMC Article
Giant solitary fibrous tumor of the diaphragm: a case report and review of literature.
Ge W, Yu DC, Jiang CP, Ding YT
Int J Clin Exp Pathol 2014;7(12):9044-9. Epub 2014 Dec 1 PMID: 25674285Free PMC Article
Wandering pleuropericardial cyst.
Agarwal PP, Seely JM, Matzinger FR
J Comput Assist Tomogr 2006 Mar-Apr;30(2):276-8. doi: 10.1097/00004728-200603000-00021. PMID: 16628047

Therapy

Intraorbital metastasis from solitary fibrous tumor.
Patel MM, Jakobiec FA, Zakka FR, Du R, Annino DJ, Borboli-Gerogiannis S, Daniels AB
Ophthalmic Plast Reconstr Surg 2013 May-Jun;29(3):e76-9. doi: 10.1097/IOP.0b013e318272f311. PMID: 23328780

Prognosis

Pericardial malignant solitary fibrous tumour with right atrial invasion - a case report and literature review.
Zhang LP, Zhang L, Wang G, Adhikari BK, Liu Q, Zhang W
J Int Med Res 2019 Jun;47(6):2716-2722. Epub 2019 Apr 28 doi: 10.1177/0300060519843734. PMID: 31032675Free PMC Article
Largest known malignant solitary fibrous tumour of the pleura-extended resection warranting cardiopulmonary bypass support.
Shanahan B, Redmond KC
Ir J Med Sci 2019 May;188(2):433-435. Epub 2018 Jul 30 doi: 10.1007/s11845-018-1879-x. PMID: 30058053
Rapid metastasis of mediastinal solitary fibrous tumor: Report a case.
Xiang Y, Tu S, Zhang F
Medicine (Baltimore) 2017 Dec;96(51):e9307. doi: 10.1097/MD.0000000000009307. PMID: 29390499Free PMC Article
Primary cardiac solitary fibrous tumors.
Taguchi S
Ann Thorac Cardiovasc Surg 2015;21(4):329-31. Epub 2015 Jul 7 doi: 10.5761/atcs.ra.15-00193. PMID: 26156195Free PMC Article
Intraorbital metastasis from solitary fibrous tumor.
Patel MM, Jakobiec FA, Zakka FR, Du R, Annino DJ, Borboli-Gerogiannis S, Daniels AB
Ophthalmic Plast Reconstr Surg 2013 May-Jun;29(3):e76-9. doi: 10.1097/IOP.0b013e318272f311. PMID: 23328780

Clinical prediction guides

The clinicopathological significance of NAB2-STAT6 gene fusions in 52 cases of intrathoracic solitary fibrous tumors.
Huang SC, Li CF, Kao YC, Chuang IC, Tai HC, Tsai JW, Yu SC, Huang HY, Lan J, Yen SL, Lin PC, Chen TC
Cancer Med 2016 Feb;5(2):159-68. Epub 2015 Dec 21 doi: 10.1002/cam4.572. PMID: 26686340Free PMC Article
MMP-7 is a highly specific negative marker for benign and malignant mesothelial cells in serous effusions.
Davidson B, Stavnes HT, Hellesylt E, Hager T, Zeppa P, Pinamonti M, Wohlschlaeger J
Hum Pathol 2016 Jan;47(1):104-8. Epub 2015 Sep 25 doi: 10.1016/j.humpath.2015.08.020. PMID: 26520416
Solitary fibrous tumors of the pleura: clinical characteristics, surgical treatment and outcome.
Magdeleinat P, Alifano M, Petino A, Le Rochais JP, Dulmet E, Galateau F, Icard P, Regnard JF
Eur J Cardiothorac Surg 2002 Jun;21(6):1087-93. doi: 10.1016/s1010-7940(02)00099-4. PMID: 12048090
Solitary fibrous tumor of the mediastinum.
Weidner N
Ultrastruct Pathol 1991 Jul-Oct;15(4-5):489-92. doi: 10.3109/01913129109016254. PMID: 1755106

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