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Cervical Soft Tissue Neoplasm

MedGen UID:
308951
•Concept ID:
C1516432
•
Neoplastic Process
Synonym: Cervical Soft Tissue Tumor

Definition

A benign or malignant mesenchymal neoplasm of the cervix. Representative examples include rhabdomyoma, alveolar soft part sarcoma, and AIDS-related Kaposi sarcoma. [from NCI]

Professional guidelines

PubMed

Advances in treatment of alveolar soft part sarcoma: an updated review.
Fujiwara T, Kunisada T, Nakata E, Nishida K, Yanai H, Nakamura T, Tanaka K, Ozaki T
Jpn J Clin Oncol 2023 Nov 5;53(11):1009-1018. doi: 10.1093/jjco/hyad102. PMID: 37626447Free PMC Article
DLL3 as an Emerging Target for the Treatment of Neuroendocrine Neoplasms.
Yao J, Bergsland E, Aggarwal R, Aparicio A, Beltran H, Crabtree JS, Hann CL, Ibrahim T, Byers LA, Sasano H, Umejiego J, Pavel M
Oncologist 2022 Nov 3;27(11):940-951. doi: 10.1093/oncolo/oyac161. PMID: 35983951Free PMC Article
Soft Tissue Sarcoma, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology.
von Mehren M, Kane JM, Agulnik M, Bui MM, Carr-Ascher J, Choy E, Connelly M, Dry S, Ganjoo KN, Gonzalez RJ, Holder A, Homsi J, Keedy V, Kelly CM, Kim E, Liebner D, McCarter M, McGarry SV, Mesko NW, Meyer C, Pappo AS, Parkes AM, Petersen IA, Pollack SM, Poppe M, Riedel RF, Schuetze S, Shabason J, Sicklick JK, Spraker MB, Zimel M, Hang LE, Sundar H, Bergman MA
J Natl Compr Canc Netw 2022 Jul;20(7):815-833. doi: 10.6004/jnccn.2022.0035. PMID: 35830886Free PMC Article

Recent clinical studies

Etiology

Soft Tissue Special Issue: Perivascular and Vascular Tumors of the Head and Neck.
Flucke U, Karanian M, Broek RWT, Thway K
Head Neck Pathol 2020 Mar;14(1):21-32. Epub 2020 Jan 16 doi: 10.1007/s12105-020-01129-z. PMID: 31950476Free PMC Article
Vascular Anomalies.
Johnson AB, Richter GT
Clin Perinatol 2018 Dec;45(4):737-749. Epub 2018 Sep 18 doi: 10.1016/j.clp.2018.07.010. PMID: 30396415
Perivascular epithelioid cell neoplasms of soft tissue and gynecologic origin: a clinicopathologic study of 26 cases and review of the literature.
Folpe AL, Mentzel T, Lehr HA, Fisher C, Balzer BL, Weiss SW
Am J Surg Pathol 2005 Dec;29(12):1558-75. doi: 10.1097/01.pas.0000173232.22117.37. PMID: 16327428
Soft tissue angiosarcomas.
Morales PH, Lindberg RD, Barkley HT Jr
Int J Radiat Oncol Biol Phys 1981 Dec;7(12):1655-9. doi: 10.1016/0360-3016(81)90188-7. PMID: 7199518
Spindle cell lipoma.
Enzinger FM, Harvey DA
Cancer 1975 Nov;36(5):1852-9. doi: 10.1002/1097-0142(197511)36:5<1852::aid-cncr2820360542>3.0.co;2-u. PMID: 1192370

Diagnosis

Advances in treatment of alveolar soft part sarcoma: an updated review.
Fujiwara T, Kunisada T, Nakata E, Nishida K, Yanai H, Nakamura T, Tanaka K, Ozaki T
Jpn J Clin Oncol 2023 Nov 5;53(11):1009-1018. doi: 10.1093/jjco/hyad102. PMID: 37626447Free PMC Article
Soft Tissue Sarcoma, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology.
von Mehren M, Kane JM, Agulnik M, Bui MM, Carr-Ascher J, Choy E, Connelly M, Dry S, Ganjoo KN, Gonzalez RJ, Holder A, Homsi J, Keedy V, Kelly CM, Kim E, Liebner D, McCarter M, McGarry SV, Mesko NW, Meyer C, Pappo AS, Parkes AM, Petersen IA, Pollack SM, Poppe M, Riedel RF, Schuetze S, Shabason J, Sicklick JK, Spraker MB, Zimel M, Hang LE, Sundar H, Bergman MA
J Natl Compr Canc Netw 2022 Jul;20(7):815-833. doi: 10.6004/jnccn.2022.0035. PMID: 35830886Free PMC Article
Repetitive trauma-induced extra-nuchal-type fibroma.
Jayaram PR, Walsh J, Lari H, Mohammad N, Mallinson PI, Ouellette HA
Skeletal Radiol 2022 Mar;51(3):681-685. Epub 2021 Sep 23 doi: 10.1007/s00256-021-03912-7. PMID: 34554278Free PMC Article
Soft Tissue Special Issue: Perivascular and Vascular Tumors of the Head and Neck.
Flucke U, Karanian M, Broek RWT, Thway K
Head Neck Pathol 2020 Mar;14(1):21-32. Epub 2020 Jan 16 doi: 10.1007/s12105-020-01129-z. PMID: 31950476Free PMC Article
Soft-tissue sarcoma.
Gilbert NF, Cannon CP, Lin PP, Lewis VO
J Am Acad Orthop Surg 2009 Jan;17(1):40-7. doi: 10.5435/00124635-200901000-00006. PMID: 19136426

Therapy

Imaging of the post-treatment neck.
Gillespie J
Clin Radiol 2020 Oct;75(10):794.e7-794.e17. Epub 2020 Jul 18 doi: 10.1016/j.crad.2020.06.011. PMID: 32690240
Microenvironment-induced cancer metastasis.
Rofstad EK
Int J Radiat Biol 2000 May;76(5):589-605. doi: 10.1080/095530000138259. PMID: 10866281
Docetaxel.
Cortes JE, Pazdur R
J Clin Oncol 1995 Oct;13(10):2643-55. doi: 10.1200/JCO.1995.13.10.2643. PMID: 7595719
Soft tissue sarcomas in childhood.
Miser JS, Pizzo PA
Pediatr Clin North Am 1985 Jun;32(3):779-800. doi: 10.1016/s0031-3955(16)34836-2. PMID: 3889805
Infusion-embolization.
Wallace S, Charnsangavej C, Carrasco CH, Bechtel W
Cancer 1984 Dec 1;54(11 Suppl):2751-65. doi: 10.1002/1097-0142(19841201)54:2+<2751::aid-cncr2820541423>3.0.co;2-5. PMID: 6093984

Prognosis

Osteosarcoma in the Thyroid Gland.
Ijeoma B, Avadhani V, Zheng S, Moore C
ORL J Otorhinolaryngol Relat Spec 2023;85(1):52-56. Epub 2022 Nov 1 doi: 10.1159/000525183. PMID: 36318896
Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Soft Tissue Tumors.
Jo VY, Demicco EG
Head Neck Pathol 2022 Mar;16(1):87-100. Epub 2022 Mar 21 doi: 10.1007/s12105-022-01425-w. PMID: 35312984Free PMC Article
The clinical and radiologic features of paediatric rhabdomyosarcoma.
Jawad N, McHugh K
Pediatr Radiol 2019 Oct;49(11):1516-1523. Epub 2019 Oct 16 doi: 10.1007/s00247-019-04386-5. PMID: 31620851
Soft-tissue sarcoma.
Gilbert NF, Cannon CP, Lin PP, Lewis VO
J Am Acad Orthop Surg 2009 Jan;17(1):40-7. doi: 10.5435/00124635-200901000-00006. PMID: 19136426
Perivascular epithelioid cell neoplasms of soft tissue and gynecologic origin: a clinicopathologic study of 26 cases and review of the literature.
Folpe AL, Mentzel T, Lehr HA, Fisher C, Balzer BL, Weiss SW
Am J Surg Pathol 2005 Dec;29(12):1558-75. doi: 10.1097/01.pas.0000173232.22117.37. PMID: 16327428

Clinical prediction guides

PET Imaging of Oral Cavity and Oropharyngeal Cancers.
Marcus C, Subramaniam RM
PET Clin 2022 Apr;17(2):223-234. Epub 2022 Mar 4 doi: 10.1016/j.cpet.2021.12.005. PMID: 35256303
MUC4 is expressed in alveolar rhabdomyosarcoma.
Forgó E, Hornick JL, Charville GW
Histopathology 2021 May;78(6):905-908. Epub 2021 Mar 16 doi: 10.1111/his.14321. PMID: 33368602Free PMC Article
Overview of the 8th Edition TNM Classification for Head and Neck Cancer.
Huang SH, O'Sullivan B
Curr Treat Options Oncol 2017 Jul;18(7):40. doi: 10.1007/s11864-017-0484-y. PMID: 28555375
Angiosarcoma.
Young RJ, Brown NJ, Reed MW, Hughes D, Woll PJ
Lancet Oncol 2010 Oct;11(10):983-91. Epub 2010 May 25 doi: 10.1016/S1470-2045(10)70023-1. PMID: 20537949
Perivascular epithelioid cell neoplasms of soft tissue and gynecologic origin: a clinicopathologic study of 26 cases and review of the literature.
Folpe AL, Mentzel T, Lehr HA, Fisher C, Balzer BL, Weiss SW
Am J Surg Pathol 2005 Dec;29(12):1558-75. doi: 10.1097/01.pas.0000173232.22117.37. PMID: 16327428

Recent systematic reviews

Hyperbaric oxygen therapy for late radiation tissue injury.
Lin ZC, Bennett MH, Hawkins GC, Azzopardi CP, Feldmeier J, Smee R, Milross C
Cochrane Database Syst Rev 2023 Aug 15;8(8):CD005005. doi: 10.1002/14651858.CD005005.pub5. PMID: 37585677Free PMC Article
Mandibular reconstruction in head and neck cancer: which is the gold standard?
Molteni G, Gazzini L, Sacchetto A, Nocini R, Comini LV, Arietti V, Locatello LG, Mannelli G
Eur Arch Otorhinolaryngol 2023 Sep;280(9):3953-3965. Epub 2023 Jun 3 doi: 10.1007/s00405-023-08050-5. PMID: 37269408
Imaging of head and neck lipoblastoma: case report and systematic review.
Lomoro P, Simonetti I, Nanni AL, Corsani G, Togni G, Fichera V, Verde F, Formica M, Trovato P, Vallone G, Gorone MSP
J Ultrasound 2021 Sep;24(3):231-239. Epub 2020 Mar 5 doi: 10.1007/s40477-020-00439-w. PMID: 32141045Free PMC Article
Oral radiation-induced sarcomas: Systematic review.
de Souza LL, Pontes HAR, Santos-Silva AR, Fernandes LA, Batista LAL, Lopes MA, Khan W, Pontes FSC
Head Neck 2020 Sep;42(9):2660-2668. Epub 2020 Apr 28 doi: 10.1002/hed.26176. PMID: 32343457
Systemic antibiotics for treating malignant wounds.
Ramasubbu DA, Smith V, Hayden F, Cronin P
Cochrane Database Syst Rev 2017 Aug 24;8(8):CD011609. doi: 10.1002/14651858.CD011609.pub2. PMID: 28837757Free PMC Article

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