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Vaginal Rhabdomyoma

MedGen UID:
277861
•Concept ID:
C1336942
•
Neoplastic Process
Synonyms: Rhabdomyoma of the Vagina; Rhabdomyoma of Vagina

Definition

A rare benign polypoid skeletal muscle neoplasm arising from the vagina. It is characterized by the presence of round striated muscle cells and strap-like skeletal muscle cells, and vascular space formations within a fibrous and myxoid stroma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVVaginal Rhabdomyoma

Recent clinical studies

Etiology

Production of basement membrane laminin and type IV collagen by tumors of striated muscle: an immunohistochemical study of rhabdomyosarcomas of different histologic types and a benign vaginal rhabdomyoma.
Autio-Harmainen H, Apaja-Sarkkinen M, Martikainen J, Taipale A, Rapola J
Hum Pathol 1986 Dec;17(12):1218-24. doi: 10.1016/s0046-8177(86)80563-9. PMID: 3539758
Vaginal polyps with pseudosarcomatous features. A clinicopathologic study of seven cases.
Miettinen M, Wahlström T, Vesterinen E, Saksela E
Cancer 1983 Mar 15;51(6):1148-51. doi: 10.1002/1097-0142(19830315)51:6<1148::aid-cncr2820510629>3.0.co;2-7. PMID: 6681596

Diagnosis

Vaginal rhabdomyoma: a case report of an uncommon and misleading neoplasm.
Attafi S, Boujelbene N, Abbes I, Doghri R, Ben Hamida N, Ghorbel R, Charfi L, Driss M, Mrad K
Pathologica 2017 Dec;109(4):382-383. PMID: 29449728
Myogenin expression in vulvovaginal spindle cell lesions: analysis of a series of cases with an emphasis on diagnostic pitfalls.
McCluggage WG, Longacre TA, Fisher C
Histopathology 2013 Oct;63(4):545-50. Epub 2013 Aug 14 doi: 10.1111/his.12205. PMID: 23944986
Two cases of benign vaginal rhabdomyoma. Case reports.
Iversen UM
APMIS 1996 Jul-Aug;104(7-8):575-8. doi: 10.1111/j.1699-0463.1996.tb04913.x. PMID: 8920811
Production of basement membrane laminin and type IV collagen by tumors of striated muscle: an immunohistochemical study of rhabdomyosarcomas of different histologic types and a benign vaginal rhabdomyoma.
Autio-Harmainen H, Apaja-Sarkkinen M, Martikainen J, Taipale A, Rapola J
Hum Pathol 1986 Dec;17(12):1218-24. doi: 10.1016/s0046-8177(86)80563-9. PMID: 3539758
Vaginal rhabdomyoma.
Chabrel CM, Beilby JO
Histopathology 1980 Nov;4(6):645-51. doi: 10.1111/j.1365-2559.1980.tb02960.x. PMID: 7439892

Prognosis

Rhabdomyoma of the vagina.
López JI, Brouard I, Eizaguirre B
Eur J Obstet Gynecol Reprod Biol 1992 Jul 3;45(2):147-8. doi: 10.1016/0028-2243(92)90231-m. PMID: 1499848
Vaginal polyps with pseudosarcomatous features. A clinicopathologic study of seven cases.
Miettinen M, Wahlström T, Vesterinen E, Saksela E
Cancer 1983 Mar 15;51(6):1148-51. doi: 10.1002/1097-0142(19830315)51:6<1148::aid-cncr2820510629>3.0.co;2-7. PMID: 6681596

Clinical prediction guides

Production of basement membrane laminin and type IV collagen by tumors of striated muscle: an immunohistochemical study of rhabdomyosarcomas of different histologic types and a benign vaginal rhabdomyoma.
Autio-Harmainen H, Apaja-Sarkkinen M, Martikainen J, Taipale A, Rapola J
Hum Pathol 1986 Dec;17(12):1218-24. doi: 10.1016/s0046-8177(86)80563-9. PMID: 3539758

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