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Pineal region immature teratoma

MedGen UID:
277516
•Concept ID:
C1335416
•
Neoplastic Process
Synonyms: Atypical Pineal Teratoma; atypical pineal teratoma; Immature Teratoma of Pineal Area; immature teratoma of pineal area; Immature Teratoma of Pineal Region; immature teratoma of pineal region; Immature Teratoma of the Pineal Area; immature teratoma of the pineal area; Immature Teratoma of the Pineal Region; immature teratoma of the pineal region; Pineal Area Immature Teratoma; pineal area immature teratoma; Pineal Region Immature Teratoma; pineal region immature teratoma
 
Monarch Initiative: MONDO:0004017

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPineal region immature teratoma

Professional guidelines

PubMed

Outcome of Children and Adolescents With Primary Intracranial Germinoma Treated With Chemotherapy and Reduced Dose-Field Irradiation: A Prospective Brazilian Experience.
Cappellano AM, Dassi N, Mançano B, Epelman S, Almeida DB, Cavalheiro S, Dastoli PA, Seixas MT, Nicacio JM, Costa MD, Silva FA, Aguiar SS, Almeida CR, Teixeira GR, Chen M, Figueiredo ML, Silva NS, Finlay JL
JCO Glob Oncol 2023 Apr;9:e2200257. doi: 10.1200/GO.22.00257. PMID: 37075267Free PMC Article
Recent advances in molecular biology and treatment strategies for intracranial germ cell tumors.
Huang X, Zhang R, Mao Y, Zhou LF, Zhang C
World J Pediatr 2016 Aug;12(3):275-282. Epub 2016 Jun 29 doi: 10.1007/s12519-016-0021-2. PMID: 27351562
Management of primary intracranial germ cell tumors.
Kyritsis AP
J Neurooncol 2010 Jan;96(2):143-9. Epub 2009 Jul 9 doi: 10.1007/s11060-009-9951-z. PMID: 19588227

Recent clinical studies

Etiology

Brain and Spinal Tumors Originating from the Germ Line Cells.
Wong TT, Tsai ML, Chang H, Hsieh KL, Ho DM, Lin SC, Yen HJ, Chen YW, Lee HL, Yang TF
Adv Exp Med Biol 2023;1405:421-455. doi: 10.1007/978-3-031-23705-8_16. PMID: 37452948
Second-look surgery for pineal region tumors.
Ogiwara H
Childs Nerv Syst 2023 Sep;39(9):2349-2352. Epub 2022 Oct 1 doi: 10.1007/s00381-022-05676-4. PMID: 36181520
Simultaneous single-trajectory endoscopic biopsy and third ventriculostomy in pediatric pineal region tumors.
Liu W, Raynald, Tian Y, Gong J, Ma Z, Ma'ruf L, Li C
Acta Neurol Belg 2021 Dec;121(6):1535-1542. Epub 2020 Jun 6 doi: 10.1007/s13760-020-01387-2. PMID: 32506355
Pineal Atypical Teratoid Rhabdoid Tumor in a 5-Month-Old Child.
Gendle C, Karthigeyan M, Salunke P, Gupta K
Pediatr Neurosurg 2020;55(6):404-408. Epub 2020 Dec 10 doi: 10.1159/000511995. PMID: 33302285
Germ cell tumours.
Talerman A
Ann Pathol 1985;5(3):145-57. PMID: 3000396

Diagnosis

Second-look surgery for pineal region tumors.
Ogiwara H
Childs Nerv Syst 2023 Sep;39(9):2349-2352. Epub 2022 Oct 1 doi: 10.1007/s00381-022-05676-4. PMID: 36181520
Histopathology of pineal germ cell tumors.
Vasiljevic A, Szathmari A, Champier J, Fèvre-Montange M, Jouvet A
Neurochirurgie 2015 Apr-Jun;61(2-3):130-7. Epub 2014 Apr 13 doi: 10.1016/j.neuchi.2013.06.006. PMID: 24726316
Ruptured intracranial dermoid cysts.
El-Bahy K, Kotb A, Galal A, El-Hakim A
Acta Neurochir (Wien) 2006 Apr;148(4):457-62. Epub 2006 Jan 27 doi: 10.1007/s00701-005-0722-0. PMID: 16437187
Suprasellar germinoma.
Takeuchi J, Handa H, Nagata I
J Neurosurg 1978 Jul;49(1):41-8. doi: 10.3171/jns.1978.49.1.0041. PMID: 660267
SURGICAL REMOVAL OF TERATOMA OF THE PINEAL REGION.
CHEN KP, CHU CP, TANG CS, CHANG FL
Chin Med J 1964 Apr;83:241-7. PMID: 14150945

Therapy

Recent advances in molecular biology and treatment strategies for intracranial germ cell tumors.
Huang X, Zhang R, Mao Y, Zhou LF, Zhang C
World J Pediatr 2016 Aug;12(3):275-282. Epub 2016 Jun 29 doi: 10.1007/s12519-016-0021-2. PMID: 27351562
Ruptured intracranial dermoid cysts.
El-Bahy K, Kotb A, Galal A, El-Hakim A
Acta Neurochir (Wien) 2006 Apr;148(4):457-62. Epub 2006 Jan 27 doi: 10.1007/s00701-005-0722-0. PMID: 16437187
Therapeutic strategies and surgical results for pineal region tumours.
Tamaki N, Yin D
J Clin Neurosci 2000 Mar;7(2):125-8. doi: 10.1054/jocn.1999.0164. PMID: 10844797
Pineal region tumors of childhood.
Packer RJ, Sutton LN, Rosenstock JG, Rorke LB, Bilaniuk LT, Zimmerman RA, Littman PA, Bruce DA, Schut L
Pediatrics 1984 Jul;74(1):97-102. PMID: 6739222
Surgical removal of pineal tumors (pinealomas and teratomas). Experience in a series of 19 cases.
Suzuki J, Iwabuchi T
J Neurosurg 1965 Dec;23(6):565-71. doi: 10.3171/jns.1965.23.6.0565. PMID: 5861139

Prognosis

Brain and Spinal Tumors Originating from the Germ Line Cells.
Wong TT, Tsai ML, Chang H, Hsieh KL, Ho DM, Lin SC, Yen HJ, Chen YW, Lee HL, Yang TF
Adv Exp Med Biol 2023;1405:421-455. doi: 10.1007/978-3-031-23705-8_16. PMID: 37452948
Second-look surgery for pineal region tumors.
Ogiwara H
Childs Nerv Syst 2023 Sep;39(9):2349-2352. Epub 2022 Oct 1 doi: 10.1007/s00381-022-05676-4. PMID: 36181520
Simultaneous single-trajectory endoscopic biopsy and third ventriculostomy in pediatric pineal region tumors.
Liu W, Raynald, Tian Y, Gong J, Ma Z, Ma'ruf L, Li C
Acta Neurol Belg 2021 Dec;121(6):1535-1542. Epub 2020 Jun 6 doi: 10.1007/s13760-020-01387-2. PMID: 32506355
Adult Atypical Teratoid/Rhabdoid Tumors.
Wu WW, Bi WL, Kang YJ, Ramkissoon SH, Prasad S, Shih HA, Reardon DA, Dunn IF
World Neurosurg 2016 Jan;85:197-204. Epub 2015 Sep 4 doi: 10.1016/j.wneu.2015.08.076. PMID: 26344637
Neuropathology of pineal region tumors.
Scheithauer BW
Clin Neurosurg 1985;32:351-83. PMID: 3905145

Clinical prediction guides

Second-look surgery for pineal region tumors.
Ogiwara H
Childs Nerv Syst 2023 Sep;39(9):2349-2352. Epub 2022 Oct 1 doi: 10.1007/s00381-022-05676-4. PMID: 36181520
Pineal region teratoma with metastases in uncommon locations: a case report.
AlRefaei B, Al Haj Husain T, Alwaw R, Salama FA, Hamzeh G
J Med Case Rep 2022 Jun 23;16(1):261. doi: 10.1186/s13256-022-03454-z. PMID: 35739572Free PMC Article
Adult Atypical Teratoid/Rhabdoid Tumors.
Wu WW, Bi WL, Kang YJ, Ramkissoon SH, Prasad S, Shih HA, Reardon DA, Dunn IF
World Neurosurg 2016 Jan;85:197-204. Epub 2015 Sep 4 doi: 10.1016/j.wneu.2015.08.076. PMID: 26344637
Germ cell tumours.
Talerman A
Ann Pathol 1985;5(3):145-57. PMID: 3000396
Suprasellar germinoma.
Takeuchi J, Handa H, Nagata I
J Neurosurg 1978 Jul;49(1):41-8. doi: 10.3171/jns.1978.49.1.0041. PMID: 660267

Recent systematic reviews

Radiological image features of the atypical teratoid/rhabdoid tumor in adults: a systematic review.
Kanoto M, Toyoguchi Y, Hosoya T, Kuchiki M, Sugai Y
Clin Neuroradiol 2015 Mar;25(1):55-60. Epub 2014 Jan 30 doi: 10.1007/s00062-013-0282-2. PMID: 24477665

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