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Minor Salivary Gland Small Cell Neuroendocrine Carcinoma

MedGen UID:
277373
Concept ID:
C1334770
Neoplastic Process
Synonyms: Minor Salivary Gland Neuroendocrine Carcinoma; Neuroendocrine Carcinoma of Minor Salivary Gland; Neuroendocrine Carcinoma of the Minor Salivary Gland

Definition

An infrequent small cell carcinoma that arises from a minor salivary gland. It is characterized by the presence of neuroendocrine differentiation and a high number of mitotic figures. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMinor Salivary Gland Small Cell Neuroendocrine Carcinoma

Recent clinical studies

Etiology

Palsgrove DN
Semin Diagn Pathol 2024 Jul;41(4):173-181. Epub 2024 Jun 13 doi: 10.1053/j.semdp.2024.06.003. PMID: 38879353
Batra N, Mishra P, Pai T, Jiwnani S, Karimundackal G, Tiwari V, Purandare N, Janu A, Noronha V, Joshi A, Prabhash K, Tibdewal A, Agarwal JP, Pramesh CS, Kaushal RK
Ann Diagn Pathol 2024 Jun;70:152283. Epub 2024 Feb 24 doi: 10.1016/j.anndiagpath.2024.152283. PMID: 38447254
Haymerle G, Schneider S, Harris L, Häupl T, Schopper C, Pammer J, Grasl MCh, Erovic BM
Eur Arch Otorhinolaryngol 2016 Sep;273(9):2717-26. Epub 2015 Oct 23 doi: 10.1007/s00405-015-3805-4. PMID: 26498950
Spiro RH, Huvos AG, Strong EW
Cancer 1978 Mar;41(3):924-35. doi: 10.1002/1097-0142(197803)41:3<924::aid-cncr2820410321>3.0.co;2-l. PMID: 638978
Spiro RH, Koss LG, Hajdu SI, Strong EW
Cancer 1973 Jan;31(1):117-29. doi: 10.1002/1097-0142(197301)31:1<117::aid-cncr2820310116>3.0.co;2-7. PMID: 4345606

Diagnosis

Palsgrove DN
Semin Diagn Pathol 2024 Jul;41(4):173-181. Epub 2024 Jun 13 doi: 10.1053/j.semdp.2024.06.003. PMID: 38879353
Zhang Y, Han W, Zhou J, Yong X
Diagn Pathol 2022 Mar 27;17(1):35. doi: 10.1186/s13000-022-01216-5. PMID: 35346255Free PMC Article
Rooper LM
Head Neck Pathol 2019 Sep;13(3):476-484. Epub 2019 Mar 18 doi: 10.1007/s12105-019-01010-8. PMID: 30887392Free PMC Article
Urban SD, Hall JM, Bentkover SH, Kadish SP
J Oral Maxillofac Surg 2002 Aug;60(8):958-62. doi: 10.1053/joms.2002.33873. PMID: 12149749
Fonseca I, Soares J
Semin Diagn Pathol 1996 May;13(2):128-37. PMID: 8734419

Therapy

Nico MM, Nakano de Melo J, Lourenço SV
J Am Acad Dermatol 2010 Feb;62(2):233-8. Epub 2009 Dec 11 doi: 10.1016/j.jaad.2009.06.038. PMID: 20005008
Rosenthal DI, Chambers MS, Weber RS, Eisbruch A
Semin Oncol 2004 Dec;31(6 Suppl 18):25-8. doi: 10.1053/j.seminoncol.2004.12.008. PMID: 15726519
Ghannoum JE, Freedman PD
Am J Surg Pathol 2004 Jan;28(1):89-93. doi: 10.1097/00000478-200401000-00010. PMID: 14707869

Prognosis

Batra N, Mishra P, Pai T, Jiwnani S, Karimundackal G, Tiwari V, Purandare N, Janu A, Noronha V, Joshi A, Prabhash K, Tibdewal A, Agarwal JP, Pramesh CS, Kaushal RK
Ann Diagn Pathol 2024 Jun;70:152283. Epub 2024 Feb 24 doi: 10.1016/j.anndiagpath.2024.152283. PMID: 38447254
Haymerle G, Schneider S, Harris L, Häupl T, Schopper C, Pammer J, Grasl MCh, Erovic BM
Eur Arch Otorhinolaryngol 2016 Sep;273(9):2717-26. Epub 2015 Oct 23 doi: 10.1007/s00405-015-3805-4. PMID: 26498950
Cheuk W, Chan JK
Histopathology 2007 Jul;51(1):1-20. Epub 2007 May 31 doi: 10.1111/j.1365-2559.2007.02719.x. PMID: 17539914
Spiro RH, Koss LG, Hajdu SI, Strong EW
Cancer 1973 Jan;31(1):117-29. doi: 10.1002/1097-0142(197301)31:1<117::aid-cncr2820310116>3.0.co;2-7. PMID: 4345606
Koss LG, Spiro RH, Hajdu S
Cancer 1972 Sep;30(3):737-41. doi: 10.1002/1097-0142(197209)30:3<737::aid-cncr2820300322>3.0.co;2-m. PMID: 4342409

Clinical prediction guides

Val-Bernal JF, Herrera G, Fernández-Flórez A, Martino M
Rom J Morphol Embryol 2022 Jan-Mar;63(1):221-228. doi: 10.47162/RJME.63.1.25. PMID: 36074688Free PMC Article
Cheuk W, Chan JK
Histopathology 2007 Jul;51(1):1-20. Epub 2007 May 31 doi: 10.1111/j.1365-2559.2007.02719.x. PMID: 17539914
Andreadis D, Epivatianos A, Poulopoulos A, Nomikos A, Papazoglou G, Antoniades D, Barbatis C
Oral Oncol 2006 Jan;42(1):57-65. Epub 2005 Sep 2 doi: 10.1016/j.oraloncology.2005.06.014. PMID: 16140564

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