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Metastatic Bladder Paraganglioma

MedGen UID:
277328
•Concept ID:
C1334563
•
Neoplastic Process
Synonyms: Malignant Bladder Paraganglioma; Malignant Paraganglioma of Bladder; Malignant Paraganglioma of the Bladder; Malignant Paraganglioma of the Urinary Bladder; Malignant Paraganglioma of Urinary Bladder; Malignant Urinary Bladder Paraganglioma

Definition

An extra-adrenal sympathetic paraganglioma of the bladder that metastasizes to other anatomic sites. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic Bladder Paraganglioma

Professional guidelines

PubMed

Histologic variants of urothelial carcinoma: differential diagnosis and clinical implications.
Lopez-Beltran A, Cheng L
Hum Pathol 2006 Nov;37(11):1371-88. Epub 2006 Jul 31 doi: 10.1016/j.humpath.2006.05.009. PMID: 16949919
Surgical management of hereditary pheochromocytoma.
Yip L, Lee JE, Shapiro SE, Waguespack SG, Sherman SI, Hoff AO, Gagel RF, Arens JF, Evans DB
J Am Coll Surg 2004 Apr;198(4):525-34; discussion 534-5. doi: 10.1016/j.jamcollsurg.2003.12.001. PMID: 15051000
Pheochromocytoma--recognition and management.
Ram CV, Engelman K
Curr Probl Cardiol 1979 Apr;4(1):1-37. doi: 10.1016/s0146-2806(79)80003-1. PMID: 42512

Recent clinical studies

Etiology

A clinicopathological and immunohistochemical study of non-urothelial bladder tumours.
Kaur S, Gupta A, Gulwani HV
Indian J Cancer 2019 Jul-Sep;56(3):254-260. doi: 10.4103/ijc.IJC_459_17. PMID: 31389390
Identification of succinate dehydrogenase-deficient bladder paragangliomas.
Mason EF, Sadow PM, Wagner AJ, Remillard SP, Flood TA, Belanger EC, Hornick JL, Barletta JA
Am J Surg Pathol 2013 Oct;37(10):1612-8. doi: 10.1097/PAS.0b013e318293d83c. PMID: 23797725
Pheochromocytoma of the urinary bladder: a systematic review of the contemporary literature.
Beilan JA, Lawton A, Hajdenberg J, Rosser CJ
BMC Urol 2013 Apr 29;13:22. doi: 10.1186/1471-2490-13-22. PMID: 23627260Free PMC Article
[¹³¹I]Metaiodobenzylguanidine therapy in neural crest tumors: varying outcome in different histopathologies.
Rachh SH, Abhyankar S, Basu S
Nucl Med Commun 2011 Dec;32(12):1201-10. doi: 10.1097/MNM.0b013e32834bad97. PMID: 21968432
Multiple endocrine neoplasia, type 2b.
Carney JA, Sizemore GW, Hayles AB
Pathobiol Annu 1978;8:105-53. PMID: 364372

Diagnosis

Malignant paraganglioma of the bladder: a case report and review of the literature.
Quist EE, Javadzadeh BM, Johannesen E, Johansson SL, Lele SM, Kozel JA
Pathol Res Pract 2015 Feb;211(2):183-8. Epub 2014 Nov 27 doi: 10.1016/j.prp.2014.10.009. PMID: 25512259
Paragangliomas: clinical overview.
Young WF Jr
Ann N Y Acad Sci 2006 Aug;1073:21-9. doi: 10.1196/annals.1353.002. PMID: 17102068
Carcinoid tumors of the urinary tract and prostate.
Murali R, Kneale K, Lalak N, Delprado W
Arch Pathol Lab Med 2006 Nov;130(11):1693-706. doi: 10.5858/2006-130-1693-CTOTUT. PMID: 17076534
Cauda equina syndrome caused by primary and metastatic neoplasms.
Bagley CA, Gokaslan ZL
Neurosurg Focus 2004 Jun 15;16(6):e3. doi: 10.3171/foc.2004.16.6.3. PMID: 15202873
Extra-adrenal pheochromocytoma.
Whalen RK, Althausen AF, Daniels GH
J Urol 1992 Jan;147(1):1-10. doi: 10.1016/s0022-5347(17)37119-7. PMID: 1729490

Therapy

Micturition syncope secondary to urinary bladder paraganglioma.
Johnson JT, Cherian KE, Kapoor N, Paul TV
BMJ Case Rep 2020 Mar 12;13(3) doi: 10.1136/bcr-2019-233556. PMID: 32169989Free PMC Article
A clinicopathological and immunohistochemical study of non-urothelial bladder tumours.
Kaur S, Gupta A, Gulwani HV
Indian J Cancer 2019 Jul-Sep;56(3):254-260. doi: 10.4103/ijc.IJC_459_17. PMID: 31389390
[¹³¹I]Metaiodobenzylguanidine therapy in neural crest tumors: varying outcome in different histopathologies.
Rachh SH, Abhyankar S, Basu S
Nucl Med Commun 2011 Dec;32(12):1201-10. doi: 10.1097/MNM.0b013e32834bad97. PMID: 21968432
Surgical management of hereditary pheochromocytoma.
Yip L, Lee JE, Shapiro SE, Waguespack SG, Sherman SI, Hoff AO, Gagel RF, Arens JF, Evans DB
J Am Coll Surg 2004 Apr;198(4):525-34; discussion 534-5. doi: 10.1016/j.jamcollsurg.2003.12.001. PMID: 15051000
Pheochromocytoma--recognition and management.
Ram CV, Engelman K
Curr Probl Cardiol 1979 Apr;4(1):1-37. doi: 10.1016/s0146-2806(79)80003-1. PMID: 42512

Prognosis

A clinicopathological and immunohistochemical study of non-urothelial bladder tumours.
Kaur S, Gupta A, Gulwani HV
Indian J Cancer 2019 Jul-Sep;56(3):254-260. doi: 10.4103/ijc.IJC_459_17. PMID: 31389390
Urinary bladder malignant paraganglioma with vertebral metastasis: a case report with literature review.
Feng N, Li X, Gao HD, Liu ZL, Shi LJ, Liu WZ
Chin J Cancer 2013 Nov;32(11):624-8. Epub 2013 May 14 doi: 10.5732/cjc.012.10317. PMID: 23668927Free PMC Article
Pheochromocytoma of the urinary bladder: a systematic review of the contemporary literature.
Beilan JA, Lawton A, Hajdenberg J, Rosser CJ
BMC Urol 2013 Apr 29;13:22. doi: 10.1186/1471-2490-13-22. PMID: 23627260Free PMC Article
From the Archives of the AFIP: neoplasms of the urinary bladder: radiologic-pathologic correlation.
Wong-You-Cheong JJ, Woodward PJ, Manning MA, Sesterhenn IA
Radiographics 2006 Mar-Apr;26(2):553-80. doi: 10.1148/rg.262055172. PMID: 16549617
Extra-adrenal pheochromocytoma.
Whalen RK, Althausen AF, Daniels GH
J Urol 1992 Jan;147(1):1-10. doi: 10.1016/s0022-5347(17)37119-7. PMID: 1729490

Clinical prediction guides

First-in-Humans Application of (161)Tb: A Feasibility Study Using (161)Tb-DOTATOC.
Baum RP, Singh A, Kulkarni HR, Bernhardt P, Rydén T, Schuchardt C, Gracheva N, Grundler PV, Köster U, Müller D, Pröhl M, Zeevaart JR, Schibli R, van der Meulen NP, Müller C
J Nucl Med 2021 Oct;62(10):1391-1397. Epub 2021 Feb 5 doi: 10.2967/jnumed.120.258376. PMID: 33547209Free PMC Article
A clinicopathological and immunohistochemical study of non-urothelial bladder tumours.
Kaur S, Gupta A, Gulwani HV
Indian J Cancer 2019 Jul-Sep;56(3):254-260. doi: 10.4103/ijc.IJC_459_17. PMID: 31389390
Primary well differentiated neuroendocrine tumor of the filum terminale. Case report and literature review.
Revuelta Barbero JM, Saab Mazzei A, Cotúa Quinteros C, de Reina L
Neurocirugia (Astur : Engl Ed) 2018 Sep-Oct;29(5):244-249. Epub 2017 Dec 30 doi: 10.1016/j.neucir.2017.11.002. PMID: 29295804
Urinary bladder malignant paraganglioma with vertebral metastasis: a case report with literature review.
Feng N, Li X, Gao HD, Liu ZL, Shi LJ, Liu WZ
Chin J Cancer 2013 Nov;32(11):624-8. Epub 2013 May 14 doi: 10.5732/cjc.012.10317. PMID: 23668927Free PMC Article
[¹³¹I]Metaiodobenzylguanidine therapy in neural crest tumors: varying outcome in different histopathologies.
Rachh SH, Abhyankar S, Basu S
Nucl Med Commun 2011 Dec;32(12):1201-10. doi: 10.1097/MNM.0b013e32834bad97. PMID: 21968432

Recent systematic reviews

Pheochromocytoma of the urinary bladder: a systematic review of the contemporary literature.
Beilan JA, Lawton A, Hajdenberg J, Rosser CJ
BMC Urol 2013 Apr 29;13:22. doi: 10.1186/1471-2490-13-22. PMID: 23627260Free PMC Article

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