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Peritoneal Gastrointestinal Stromal Tumor

MedGen UID:
275363
•Concept ID:
C1519009
•
Neoplastic Process
Synonyms: Peritoneal EGIST; Peritoneal Extragastrointestinal Stromal Tumor

Definition

A gastrointestinal stromal tumor that arises from the peritoneum. This is an extragastrointestinal tumor, meaning that it does not arise directly from the gastrointestinal tract. [from NCI]

Professional guidelines

PubMed

Gastrointestinal stromal tumor: role of interventional radiology in diagnosis and treatment.
Avritscher R, Gupta S
Hematol Oncol Clin North Am 2009 Feb;23(1):129-37, ix. doi: 10.1016/j.hoc.2008.11.002. PMID: 19248976
Gastrointestinal stromal tumors: epidemiology, clinical picture, diagnosis, prognosis and treatment.
Cichoz-Lach H, Kasztelan-Szczerbińska B, Słomka M
Pol Arch Med Wewn 2008 Apr;118(4):216-21. PMID: 18575421
The histopathological differential diagnosis of gastrointestinal stromal tumours.
Graadt van Roggen JF, van Velthuysen ML, Hogendoorn PC
J Clin Pathol 2001 Feb;54(2):96-102. doi: 10.1136/jcp.54.2.96. PMID: 11215292Free PMC Article

Recent clinical studies

Etiology

Gastrointestinal stromal tumors: a comprehensive radiological review.
Inoue A, Ota S, Yamasaki M, Batsaikhan B, Furukawa A, Watanabe Y
Jpn J Radiol 2022 Nov;40(11):1105-1120. Epub 2022 Jul 9 doi: 10.1007/s11604-022-01305-x. PMID: 35809209Free PMC Article
Gastrointestinal Stromal Tumours.
Sunamak O, Gul MO, Subasi IE, Donmez T, Ozkara S
J Coll Physicians Surg Pak 2021 Sep;31(9):1089-1093. doi: 10.29271/jcpsp.2021.09.1089. PMID: 34500527
Diagnoses and Difficulties in Mesenteric Pathology.
Dashti NK, Shi C
Surg Pathol Clin 2020 Sep;13(3):521-556. Epub 2020 Jul 15 doi: 10.1016/j.path.2020.06.001. PMID: 32773198
Defining Tumor Rupture in Gastrointestinal Stromal Tumor.
Nishida T, Hølmebakk T, Raut CP, Rutkowski P
Ann Surg Oncol 2019 Jun;26(6):1669-1675. Epub 2019 Mar 13 doi: 10.1245/s10434-019-07297-9. PMID: 30868512Free PMC Article
Surgical management of gastrointestinal stromal tumors: analysis of outcome with respect to surgical margins and technique.
Everett M, Gutman H
J Surg Oncol 2008 Dec 15;98(8):588-93. doi: 10.1002/jso.21030. PMID: 19072850

Diagnosis

Deciphering the tumor immune microenvironment of imatinib-resistance in advanced gastrointestinal stromal tumors at single-cell resolution.
Liu X, Yu J, Li Y, Shi H, Jiao X, Liu X, Guo D, Li Z, Tian Y, Dai F, Niu Z, Zhou Y
Cell Death Dis 2024 Mar 5;15(3):190. doi: 10.1038/s41419-024-06571-3. PMID: 38443340Free PMC Article
Clinical and Morphological Characteristics of Gastrointestinal Stromal Tumor.
Munteanu A, Patrascu S, Bordu S, Laskou S, Surlin V, Radu P
Chirurgia (Bucur) 2023 Dec;118(6):618-623. doi: 10.21614/chirurgia.2023.v.118.i.6.p.618. PMID: 38228594
Gastrointestinal Stromal Tumours.
Sunamak O, Gul MO, Subasi IE, Donmez T, Ozkara S
J Coll Physicians Surg Pak 2021 Sep;31(9):1089-1093. doi: 10.29271/jcpsp.2021.09.1089. PMID: 34500527
Diagnoses and Difficulties in Mesenteric Pathology.
Dashti NK, Shi C
Surg Pathol Clin 2020 Sep;13(3):521-556. Epub 2020 Jul 15 doi: 10.1016/j.path.2020.06.001. PMID: 32773198
Nonovarian Mimics of Ovarian Malignancy.
Shetty M
Semin Ultrasound CT MR 2019 Aug;40(4):319-331. Epub 2019 Apr 18 doi: 10.1053/j.sult.2019.04.003. PMID: 31375172

Therapy

Deciphering the tumor immune microenvironment of imatinib-resistance in advanced gastrointestinal stromal tumors at single-cell resolution.
Liu X, Yu J, Li Y, Shi H, Jiao X, Liu X, Guo D, Li Z, Tian Y, Dai F, Niu Z, Zhou Y
Cell Death Dis 2024 Mar 5;15(3):190. doi: 10.1038/s41419-024-06571-3. PMID: 38443340Free PMC Article
Anti-KIT DNA Aptamer for Targeted Labeling of Gastrointestinal Stromal Tumor.
Banerjee S, Yoon H, Yebra M, Tang CM, Gilardi M, Shankara Narayanan JS, White RR, Sicklick JK, Ray P
Mol Cancer Ther 2020 May;19(5):1173-1182. Epub 2020 Mar 3 doi: 10.1158/1535-7163.MCT-19-0959. PMID: 32127469Free PMC Article
Advanced gastrointestinal stromal tumor patients benefit from palliative surgery after tyrosine kinase inhibitors therapy.
Qiu HB, Zhou ZG, Feng XY, Liu XC, Guo J, Ma MZ, Chen YB, Sun XW, Zhou ZW
Medicine (Baltimore) 2018 Jan;97(2):e9097. doi: 10.1097/MD.0000000000009097. PMID: 29480823Free PMC Article
Needle tract seeding after percutaneous biopsy of sarcoma: Risk/benefit considerations.
Berger-Richardson D, Swallow CJ
Cancer 2017 Feb 15;123(4):560-567. Epub 2016 Nov 2 doi: 10.1002/cncr.30370. PMID: 27859013
Gastrointestinal stromal tumors.
Casper ES
Curr Treat Options Oncol 2000 Aug;1(3):267-73. doi: 10.1007/s11864-000-0039-4. PMID: 12057170

Prognosis

Clinical and Morphological Characteristics of Gastrointestinal Stromal Tumor.
Munteanu A, Patrascu S, Bordu S, Laskou S, Surlin V, Radu P
Chirurgia (Bucur) 2023 Dec;118(6):618-623. doi: 10.21614/chirurgia.2023.v.118.i.6.p.618. PMID: 38228594
Gastrointestinal Stromal Tumours.
Sunamak O, Gul MO, Subasi IE, Donmez T, Ozkara S
J Coll Physicians Surg Pak 2021 Sep;31(9):1089-1093. doi: 10.29271/jcpsp.2021.09.1089. PMID: 34500527
Defining Tumor Rupture in Gastrointestinal Stromal Tumor.
Nishida T, Hølmebakk T, Raut CP, Rutkowski P
Ann Surg Oncol 2019 Jun;26(6):1669-1675. Epub 2019 Mar 13 doi: 10.1245/s10434-019-07297-9. PMID: 30868512Free PMC Article
Gastrointestinal stromal tumors: epidemiology, clinical picture, diagnosis, prognosis and treatment.
Cichoz-Lach H, Kasztelan-Szczerbińska B, Słomka M
Pol Arch Med Wewn 2008 Apr;118(4):216-21. PMID: 18575421
Gastrointestinal stromal tumors.
Casper ES
Curr Treat Options Oncol 2000 Aug;1(3):267-73. doi: 10.1007/s11864-000-0039-4. PMID: 12057170

Clinical prediction guides

Gastrointestinal stromal tumors: a comprehensive radiological review.
Inoue A, Ota S, Yamasaki M, Batsaikhan B, Furukawa A, Watanabe Y
Jpn J Radiol 2022 Nov;40(11):1105-1120. Epub 2022 Jul 9 doi: 10.1007/s11604-022-01305-x. PMID: 35809209Free PMC Article
Gastrointestinal stromal tumors: relationship between preoperative CT features and pathologic risk stratification.
Grazzini G, Guerri S, Cozzi D, Danti G, Gasperoni S, Pradella S, Miele V
Tumori 2021 Dec;107(6):556-563. Epub 2021 Feb 23 doi: 10.1177/0300891621996447. PMID: 33620027
Defining Tumor Rupture in Gastrointestinal Stromal Tumor.
Nishida T, Hølmebakk T, Raut CP, Rutkowski P
Ann Surg Oncol 2019 Jun;26(6):1669-1675. Epub 2019 Mar 13 doi: 10.1245/s10434-019-07297-9. PMID: 30868512Free PMC Article
Surgical management of gastrointestinal stromal tumors: analysis of outcome with respect to surgical margins and technique.
Everett M, Gutman H
J Surg Oncol 2008 Dec 15;98(8):588-93. doi: 10.1002/jso.21030. PMID: 19072850
Gastrointestinal stromal tumors: epidemiology, clinical picture, diagnosis, prognosis and treatment.
Cichoz-Lach H, Kasztelan-Szczerbińska B, Słomka M
Pol Arch Med Wewn 2008 Apr;118(4):216-21. PMID: 18575421

Recent systematic reviews

Liver resection for metastatic GIST tumor improves survival in the era of tyrosine kinase inhibitors: a systematic review and meta-analysis.
Rahimi-Ardabily A, Murdande S, Dong M, Gu KW, Zhang B, Miller K, Aploks K, Da Dong X
Langenbecks Arch Surg 2023 Sep 23;408(1):373. doi: 10.1007/s00423-023-03052-7. PMID: 37740754
The association of genitourinary cancer among Saudi patients with gastrointestinal stromal tumors and a systematic literature review.
Seyam R, Chaer KA, Abouelkhair A, Almouh A, Alzahrani O, Sayed AG, Alghafees M, Alhamidi RA, Al-Gonaim A, Al-Hussain T, Amin TM, Altaweel W
Sci Rep 2023 Mar 15;13(1):4325. doi: 10.1038/s41598-023-28060-x. PMID: 36922517Free PMC Article
Mitotically Active Cellular Fibroma of the Ovary Recurring After the Longest Interval of Time (16 yr): A Challenging Case With Systematic Literature Review.
Olivadese R, Ramponi A, Boldorini R, Dalla Dea G, Palicelli A
Int J Gynecol Pathol 2021 Sep 1;40(5):441-447. doi: 10.1097/PGP.0000000000000731. PMID: 33252401

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