U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Mucinous ovarian cancer

MedGen UID:
274767
Concept ID:
C1518233
Neoplastic Process
Synonyms: Malignant Ovarian Mucinous Neoplasm; malignant ovarian mucinous neoplasm; Malignant Ovarian Mucinous Tumor; malignant ovarian mucinous tumor; malignant ovarian mucinous tumour; mucinous ovarian cancer; ovarian mucinous neoplasm, malignant
 
Monarch Initiative: MONDO:0024282

Definition

An invasive malignant neoplasm that arises from the ovary and is characterized by the presence of malignant epithelial cells that contain intracytoplasmic mucin and may resemble the epithelial cells of the endocervix or gastrointestinal tract. It includes mucinous adenocarcinoma and mucinous adenocarcinofibroma. [from NCI]

Professional guidelines

PubMed

McLeavy L, Rahman B, Kristeleit R, Ledermann J, Lockley M, McCormack M, Mould T, Side L, Lanceley A
Int J Gynecol Cancer 2020 Feb;30(2):221-226. Epub 2019 Nov 19 doi: 10.1136/ijgc-2019-000630. PMID: 31744886
Rahman B, Lanceley A, Kristeleit RS, Ledermann JA, Lockley M, McCormack M, Mould T, Side L
J Med Genet 2019 Mar;56(3):195-198. Epub 2018 Mar 13 doi: 10.1136/jmedgenet-2017-105140. PMID: 29535157
Mueller JJ, Schlappe BA, Kumar R, Olvera N, Dao F, Abu-Rustum N, Aghajanian C, DeLair D, Hussein YR, Soslow RA, Levine DA, Weigelt B
Gynecol Oncol 2018 Jul;150(1):127-135. Epub 2018 May 22 doi: 10.1016/j.ygyno.2018.05.008. PMID: 29793804Free PMC Article

Curated

NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Ovarian Cancer Including Fallopian Tube Cancer and Primary Peritoneal Cancer, 2024

UK NICE Clinical guideline (CG122), Ovarian cancer: recognition and initial management, 2023

Recent clinical studies

Etiology

Marmolejo DH, Wong MYZ, Bajalica-Lagercrantz S, Tischkowitz M, Balmaña J; extended ERN-GENTURIS Thematic Group 3
Eur J Med Genet 2021 Dec;64(12):104350. Epub 2021 Oct 1 doi: 10.1016/j.ejmg.2021.104350. PMID: 34606975
Konstantinopoulos PA, Norquist B, Lacchetti C, Armstrong D, Grisham RN, Goodfellow PJ, Kohn EC, Levine DA, Liu JF, Lu KH, Sparacio D, Annunziata CM
J Clin Oncol 2020 Apr 10;38(11):1222-1245. Epub 2020 Jan 27 doi: 10.1200/JCO.19.02960. PMID: 31986064Free PMC Article
Salgado-Ceballos I, Ríos J, Pérez-Montiel D, Gallardo L, Barquet-Muñoz S, Salcedo-Hernández R, Pérez-Plasencia C, Herrera LA, Cantú de León DF
Int J Surg 2017 May;41:1-5. Epub 2017 Mar 14 doi: 10.1016/j.ijsu.2017.03.023. PMID: 28315410
Hoogendam JP, Vlek CA, Witteveen PO, Verheijen R, Zweemer RP
BJOG 2017 Feb;124(3):370-378. Epub 2016 Jul 22 doi: 10.1111/1471-0528.14226. PMID: 27444115
Shi LF, Wu Y, Li CY
Menopause 2016 Apr;23(4):417-24. doi: 10.1097/GME.0000000000000550. PMID: 26506499

Diagnosis

Jacobsen F, Pushpadevan R, Viehweger F, Freytag M, Schlichter R, Gorbokon N, Büscheck F, Luebke AM, Putri D, Kluth M, Hube-Magg C, Hinsch A, Höflmayer D, Fraune C, Bernreuther C, Lebok P, Sauter G, Minner S, Steurer S, Simon R, Burandt E, Dum D, Lutz F, Marx AH, Krech T, Clauditz TS
Pathol Res Pract 2024 Apr;256:155175. Epub 2024 Jan 28 doi: 10.1016/j.prp.2024.155175. PMID: 38452580
Dum D, Menz A, Völkel C, De Wispelaere N, Hinsch A, Gorbokon N, Lennartz M, Luebke AM, Hube-Magg C, Kluth M, Fraune C, Möller K, Bernreuther C, Lebok P, Clauditz TS, Jacobsen F, Sauter G, Uhlig R, Wilczak W, Steurer S, Minner S, Marx AH, Simon R, Burandt E, Krech T
Exp Mol Pathol 2022 Jun;126:104762. Epub 2022 Apr 4 doi: 10.1016/j.yexmp.2022.104762. PMID: 35390310
Konstantinopoulos PA, Norquist B, Lacchetti C, Armstrong D, Grisham RN, Goodfellow PJ, Kohn EC, Levine DA, Liu JF, Lu KH, Sparacio D, Annunziata CM
J Clin Oncol 2020 Apr 10;38(11):1222-1245. Epub 2020 Jan 27 doi: 10.1200/JCO.19.02960. PMID: 31986064Free PMC Article
Crane EK, Brown J
Gynecol Oncol 2018 Jun;149(3):598-604. Epub 2018 Feb 9 doi: 10.1016/j.ygyno.2018.01.035. PMID: 29429591
Xu W, Rush J, Rickett K, Coward JI
Crit Rev Oncol Hematol 2016 Jun;102:26-36. Epub 2016 Mar 19 doi: 10.1016/j.critrevonc.2016.03.015. PMID: 27083591

Therapy

Konstantinopoulos PA, Norquist B, Lacchetti C, Armstrong D, Grisham RN, Goodfellow PJ, Kohn EC, Levine DA, Liu JF, Lu KH, Sparacio D, Annunziata CM
J Clin Oncol 2020 Apr 10;38(11):1222-1245. Epub 2020 Jan 27 doi: 10.1200/JCO.19.02960. PMID: 31986064Free PMC Article
Crane EK, Brown J
Gynecol Oncol 2018 Jun;149(3):598-604. Epub 2018 Feb 9 doi: 10.1016/j.ygyno.2018.01.035. PMID: 29429591
Perren TJ
Ann Oncol 2016 Apr;27 Suppl 1:i53-i57. doi: 10.1093/annonc/mdw087. PMID: 27141073
Xu W, Rush J, Rickett K, Coward JI
Crit Rev Oncol Hematol 2016 Jun;102:26-36. Epub 2016 Mar 19 doi: 10.1016/j.critrevonc.2016.03.015. PMID: 27083591
Harrison ML, Jameson C, Gore ME
Int J Gynecol Cancer 2008 Mar-Apr;18(2):209-14. Epub 2007 Jul 11 doi: 10.1111/j.1525-1438.2007.01022.x. PMID: 17624989

Prognosis

Qi X, Xu L, Wang J, Yu J, Wang Y
J Gynecol Obstet Hum Reprod 2022 Sep;51(7):102424. Epub 2022 Jun 11 doi: 10.1016/j.jogoh.2022.102424. PMID: 35697250
Gouy S, Saidani M, Maulard A, Bach-Hamba S, Bentivegna E, Leary A, Pautier P, Devouassoux-Shisheboran M, Genestie C, Morice P
Int J Gynecol Cancer 2018 Mar;28(3):493-499. doi: 10.1097/IGC.0000000000001202. PMID: 29466254
Hoogendam JP, Vlek CA, Witteveen PO, Verheijen R, Zweemer RP
BJOG 2017 Feb;124(3):370-378. Epub 2016 Jul 22 doi: 10.1111/1471-0528.14226. PMID: 27444115
Perren TJ
Ann Oncol 2016 Apr;27 Suppl 1:i53-i57. doi: 10.1093/annonc/mdw087. PMID: 27141073
Harrison ML, Jameson C, Gore ME
Int J Gynecol Cancer 2008 Mar-Apr;18(2):209-14. Epub 2007 Jul 11 doi: 10.1111/j.1525-1438.2007.01022.x. PMID: 17624989

Clinical prediction guides

Dareng EO, Tyrer JP, Barnes DR, Jones MR, Yang X, Aben KKH, Adank MA, Agata S, Andrulis IL, Anton-Culver H, Antonenkova NN, Aravantinos G, Arun BK, Augustinsson A, Balmaña J, Bandera EV, Barkardottir RB, Barrowdale D, Beckmann MW, Beeghly-Fadiel A, Benitez J, Bermisheva M, Bernardini MQ, Bjorge L, Black A, Bogdanova NV, Bonanni B, Borg A, Brenton JD, Budzilowska A, Butzow R, Buys SS, Cai H, Caligo MA, Campbell I, Cannioto R, Cassingham H, Chang-Claude J, Chanock SJ, Chen K, Chiew YE, Chung WK, Claes KBM, Colonna S; GEMO Study Collaborators; GC-HBOC Study Collaborators; EMBRACE Collaborators, Cook LS, Couch FJ, Daly MB, Dao F, Davies E, de la Hoya M, de Putter R, Dennis J, DePersia A, Devilee P, Diez O, Ding YC, Doherty JA, Domchek SM, Dörk T, du Bois A, Dürst M, Eccles DM, Eliassen HA, Engel C, Evans GD, Fasching PA, Flanagan JM, Fortner RT, Machackova E, Friedman E, Ganz PA, Garber J, Gensini F, Giles GG, Glendon G, Godwin AK, Goodman MT, Greene MH, Gronwald J; OPAL Study Group; AOCS Group, Hahnen E, Haiman CA, Håkansson N, Hamann U, Hansen TVO, Harris HR, Hartman M, Heitz F, Hildebrandt MAT, Høgdall E, Høgdall CK, Hopper JL, Huang RY, Huff C, Hulick PJ, Huntsman DG, Imyanitov EN; KConFab Investigators; HEBON Investigators, Isaacs C, Jakubowska A, James PA, Janavicius R, Jensen A, Johannsson OT, John EM, Jones ME, Kang D, Karlan BY, Karnezis A, Kelemen LE, Khusnutdinova E, Kiemeney LA, Kim BG, Kjaer SK, Komenaka I, Kupryjanczyk J, Kurian AW, Kwong A, Lambrechts D, Larson MC, Lazaro C, Le ND, Leslie G, Lester J, Lesueur F, Levine DA, Li L, Li J, Loud JT, Lu KH, Lubiński J, Mai PL, Manoukian S, Marks JR, Matsuno RK, Matsuo K, May T, McGuffog L, McLaughlin JR, McNeish IA, Mebirouk N, Menon U, Miller A, Milne RL, Minlikeeva A, Modugno F, Montagna M, Moysich KB, Munro E, Nathanson KL, Neuhausen SL, Nevanlinna H, Yie JNY, Nielsen HR, Nielsen FC, Nikitina-Zake L, Odunsi K, Offit K, Olah E, Olbrecht S, Olopade OI, Olson SH, Olsson H, Osorio A, Papi L, Park SK, Parsons MT, Pathak H, Pedersen IS, Peixoto A, Pejovic T, Perez-Segura P, Permuth JB, Peshkin B, Peterlongo P, Piskorz A, Prokofyeva D, Radice P, Rantala J, Riggan MJ, Risch HA, Rodriguez-Antona C, Ross E, Rossing MA, Runnebaum I, Sandler DP, Santamariña M, Soucy P, Schmutzler RK, Setiawan VW, Shan K, Sieh W, Simard J, Singer CF, Sokolenko AP, Song H, Southey MC, Steed H, Stoppa-Lyonnet D, Sutphen R, Swerdlow AJ, Tan YY, Teixeira MR, Teo SH, Terry KL, Terry MB; OCAC Consortium; CIMBA Consortium, Thomassen M, Thompson PJ, Thomsen LCV, Thull DL, Tischkowitz M, Titus L, Toland AE, Torres D, Trabert B, Travis R, Tung N, Tworoger SS, Valen E, van Altena AM, van der Hout AH, Van Nieuwenhuysen E, van Rensburg EJ, Vega A, Edwards DV, Vierkant RA, Wang F, Wappenschmidt B, Webb PM, Weinberg CR, Weitzel JN, Wentzensen N, White E, Whittemore AS, Winham SJ, Wolk A, Woo YL, Wu AH, Yan L, Yannoukakos D, Zavaglia KM, Zheng W, Ziogas A, Zorn KK, Kleibl Z, Easton D, Lawrenson K, DeFazio A, Sellers TA, Ramus SJ, Pearce CL, Monteiro AN, Cunningham J, Goode EL, Schildkraut JM, Berchuck A, Chenevix-Trench G, Gayther SA, Antoniou AC, Pharoah PDP
Eur J Hum Genet 2022 Mar;30(3):349-362. Epub 2022 Jan 14 doi: 10.1038/s41431-021-00987-7. PMID: 35027648Free PMC Article
Marmolejo DH, Wong MYZ, Bajalica-Lagercrantz S, Tischkowitz M, Balmaña J; extended ERN-GENTURIS Thematic Group 3
Eur J Med Genet 2021 Dec;64(12):104350. Epub 2021 Oct 1 doi: 10.1016/j.ejmg.2021.104350. PMID: 34606975
Konstantinopoulos PA, Norquist B, Lacchetti C, Armstrong D, Grisham RN, Goodfellow PJ, Kohn EC, Levine DA, Liu JF, Lu KH, Sparacio D, Annunziata CM
J Clin Oncol 2020 Apr 10;38(11):1222-1245. Epub 2020 Jan 27 doi: 10.1200/JCO.19.02960. PMID: 31986064Free PMC Article
Hisamatsu T, McGuire M, Wu SY, Rupaimoole R, Pradeep S, Bayraktar E, Noh K, Hu W, Hansen JM, Lyons Y, Gharpure KM, Nagaraja AS, Mangala LS, Mitamura T, Rodriguez-Aguayo C, Eun YG, Rose J, Bartholomeusz G, Ivan C, Lee JS, Matsuo K, Frumovitz M, Wong KK, Lopez-Berestein G, Sood AK
Mol Cancer Ther 2019 Jan;18(1):162-172. Epub 2018 Oct 10 doi: 10.1158/1535-7163.MCT-17-1050. PMID: 30305341Free PMC Article
Harrison ML, Jameson C, Gore ME
Int J Gynecol Cancer 2008 Mar-Apr;18(2):209-14. Epub 2007 Jul 11 doi: 10.1111/j.1525-1438.2007.01022.x. PMID: 17624989

Recent systematic reviews

Konstantinopoulos PA, Norquist B, Lacchetti C, Armstrong D, Grisham RN, Goodfellow PJ, Kohn EC, Levine DA, Liu JF, Lu KH, Sparacio D, Annunziata CM
J Clin Oncol 2020 Apr 10;38(11):1222-1245. Epub 2020 Jan 27 doi: 10.1200/JCO.19.02960. PMID: 31986064Free PMC Article
Santucci C, Bosetti C, Peveri G, Liu X, Bagnardi V, Specchia C, Gallus S, Lugo A
Cancer Causes Control 2019 Sep;30(9):1023-1032. Epub 2019 Jun 24 doi: 10.1007/s10552-019-01198-8. PMID: 31236793
Hoogendam JP, Vlek CA, Witteveen PO, Verheijen R, Zweemer RP
BJOG 2017 Feb;124(3):370-378. Epub 2016 Jul 22 doi: 10.1111/1471-0528.14226. PMID: 27444115
Shi LF, Wu Y, Li CY
Menopause 2016 Apr;23(4):417-24. doi: 10.1097/GME.0000000000000550. PMID: 26506499
Jordan SJ, Whiteman DC, Purdie DM, Green AC, Webb PM
Gynecol Oncol 2006 Dec;103(3):1122-9. Epub 2006 Sep 26 doi: 10.1016/j.ygyno.2006.08.012. PMID: 17005245

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NCCN, 2024
      NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Ovarian Cancer Including Fallopian Tube Cancer and Primary Peritoneal Cancer, 2024
    • NICE, 2023
      UK NICE Clinical guideline (CG122), Ovarian cancer: recognition and initial management, 2023

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...