U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Hepatic angiomyolipoma

MedGen UID:
272705
•Concept ID:
C1333962
•
Neoplastic Process
Synonym: Liver angiomyolipoma
SNOMED CT: Angiomyolipoma of liver (1196904007)
 
HPO: HP:0034832
Monarch Initiative: MONDO:0002605

Definition

A benign liver neoplasm composed of fat, vascular, and smooth muscle elements. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHepatic angiomyolipoma

Professional guidelines

PubMed

Hepatic angiomyolipoma: an international multicenter analysis on diagnosis, management and outcome.
Klompenhouwer AJ, Dwarkasing RS, Doukas M, Pellegrino S, Vilgrain V, Paradis V, Soubrane O, Beane JD, Geller DA, Nalesnik MA, Tripke V, Lang H, Schmelzle M, Pratschke J, Schöning W, Beal E, Sun S, Pawlik TM, de Man RA, Ijzermans JNM
HPB (Oxford) 2020 Apr;22(4):622-629. Epub 2019 Oct 13 doi: 10.1016/j.hpb.2019.09.004. PMID: 31619346
Management of hepatic angiomyolipoma: A systematic review.
Klompenhouwer AJ, Verver D, Janki S, Bramer WM, Doukas M, Dwarkasing RS, de Man RA, IJzermans JNM
Liver Int 2017 Sep;37(9):1272-1280. Epub 2017 Mar 6 doi: 10.1111/liv.13381. PMID: 28177188
Diagnosis and treatment of hepatic angiomyolipoma.
Ding GH, Liu Y, Wu MC, Yang GS, Yang JM, Cong WM
J Surg Oncol 2011 Jun;103(8):807-12. Epub 2011 Jan 31 doi: 10.1002/jso.21814. PMID: 21283992

Recent clinical studies

Etiology

Differentiation between hepatic angiomyolipoma and hepatocellular carcinoma in individuals who are not at-risk for hepatocellular carcinoma.
Park S, Kim MJ, Han K, Park JH, Han DH, Park YN, Kim J, Rhee H
Eur J Radiol 2023 Sep;166:110957. Epub 2023 Jul 6 doi: 10.1016/j.ejrad.2023.110957. PMID: 37451136
Clinical characteristics and outcomes of patients with hepatic angiomyolipoma: A literature review.
Calame P, Tyrode G, Weil Verhoeven D, Félix S, Klompenhouwer AJ, Di Martino V, Delabrousse E, Thévenot T
World J Gastroenterol 2021 May 21;27(19):2299-2311. doi: 10.3748/wjg.v27.i19.2299. PMID: 34040323Free PMC Article
Hepatic angiomyolipoma: mutation analysis and immunohistochemical pitfalls in diagnosis.
Yan Z, Grenert JP, Joseph NM, Ren C, Chen X, Shafizadeh N, Kakar S
Histopathology 2018 Jul;73(1):101-108. Epub 2018 Apr 19 doi: 10.1111/his.13509. PMID: 29512829Free PMC Article
Management of hepatic angiomyolipoma: A systematic review.
Klompenhouwer AJ, Verver D, Janki S, Bramer WM, Doukas M, Dwarkasing RS, de Man RA, IJzermans JNM
Liver Int 2017 Sep;37(9):1272-1280. Epub 2017 Mar 6 doi: 10.1111/liv.13381. PMID: 28177188
Hepatic angiomyolipoma: report of changing size and internal composition on follow-up examination in two cases.
Irie H, Honda H, Kuroiwa T, Yoshimitsu K, Tajima T, Jimi M, Shimada M, Taguchi K, Masuda K
J Comput Assist Tomogr 1999 Mar-Apr;23(2):310-3. doi: 10.1097/00004728-199903000-00025. PMID: 10096344

Diagnosis

Unusual Finding of a Hepatic Angiomyolipoma Mimicking a Hepatocellular Carcinoma.
Mijović K, Hohenberg F, Aigelsreiter A, Fuchsjäger MH, Mischinger HJ, Talakic E
Rofo 2023 Sep;195(9):819-820. Epub 2023 Apr 13 doi: 10.1055/a-2036-7372. PMID: 37054728
Hepatic angiomyolipoma detected using computed tomography.
Miyazaki Y, Kokudo T, Takahashi A, Amikura K, Sakamoto H
ANZ J Surg 2019 Apr;89(4):E168-E169. Epub 2018 Feb 1 doi: 10.1111/ans.14156. PMID: 29392859
Hepatic angiomyolipoma.
Petrolla AA, Xin W
Arch Pathol Lab Med 2008 Oct;132(10):1679-82. doi: 10.5858/2008-132-1679-HA. PMID: 18834230
Angiomyolipoma of the liver.
Schwartz P, Travers P, Hunt DR
Aust N Z J Surg 1989 Dec;59(12):969-71. doi: 10.1111/j.1445-2197.1989.tb07642.x. PMID: 2688628
Renal and hepatic angiomyolipoma.
Kreel L
Postgrad Med J 1985 Apr;61(714):325-7. doi: 10.1136/pgmj.61.714.325. PMID: 3895207Free PMC Article

Therapy

The differential enhancement pattern of contrast enhanced ultrasound and magnetic resonance imaging characteristics in hepatic angiomyolipoma: 7 case reports.
Kong WT, Tang M, Qiu YD, Shi J, Wu M
Clin Hemorheol Microcirc 2019;71(1):17-26. doi: 10.3233/CH-170317. PMID: 30010112
The Histopathological Features and CT/MRI Imaging Performances in Hepatic Angiomyolipoma Patients.
Ding H, Wei H, Liu H, Chen Y, Xue X, Weng H
Ann Hepatol 2017 Sep-Oct;16(5):759-764. doi: 10.5604/01.3001.0010.2769. PMID: 28809731
Management of hepatic angiomyolipoma: A systematic review.
Klompenhouwer AJ, Verver D, Janki S, Bramer WM, Doukas M, Dwarkasing RS, de Man RA, IJzermans JNM
Liver Int 2017 Sep;37(9):1272-1280. Epub 2017 Mar 6 doi: 10.1111/liv.13381. PMID: 28177188
Hepatic Angiomyolipoma Versus Hepatocellular Carcinoma in the Noncirrhotic Liver on Gadoxetic Acid-Enhanced MRI: A Diagnostic Challenge.
Lee SJ, Kim SY, Kim KW, Kim JH, Kim HJ, Lee MG, Yu ES
AJR Am J Roentgenol 2016 Sep;207(3):562-70. Epub 2016 Jun 1 doi: 10.2214/AJR.15.15602. PMID: 27248975
Computed tomographic features of lymphangioleiomyomatosis: evaluation in 138 patients.
Tobino K, Johkoh T, Fujimoto K, Sakai F, Arakawa H, Kurihara M, Kumasaka T, Koike K, Takahashi K, Seyama K
Eur J Radiol 2015 Mar;84(3):534-541. Epub 2014 Dec 19 doi: 10.1016/j.ejrad.2014.12.008. PMID: 25544557

Prognosis

Clinical characteristics and outcomes of patients with hepatic angiomyolipoma: A literature review.
Calame P, Tyrode G, Weil Verhoeven D, Félix S, Klompenhouwer AJ, Di Martino V, Delabrousse E, Thévenot T
World J Gastroenterol 2021 May 21;27(19):2299-2311. doi: 10.3748/wjg.v27.i19.2299. PMID: 34040323Free PMC Article
Rare benign tumors of the liver: still rare?
Bertino G, Ardiri A, Demma S, GiuseppeCalvagno S, Toro A, Basile E, Campagna D, Ferraro G, Frazzetto E, Proiti M, Malaguarnera G, Bertino N, Malaguarnera M, Malaguarnera M, Amaradio MD, Pricoco G, Di Carlo I
J Gastrointest Cancer 2014 Jun;45(2):202-17. doi: 10.1007/s12029-014-9580-4. PMID: 24510731Free PMC Article
Hepatic angiomyolipoma: contrast patterns with SonoVue-enhanced real-time gray-scale ultrasonography.
Wei RX, Wang WP, Ding H, Huang BJ, Li CL, Fan PL, Hou J, He NA
Asian Pac J Cancer Prev 2012;13(2):493-7. doi: 10.7314/apjcp.2012.13.2.493. PMID: 22524813
Education and Imaging. Hepatobiliary and pancreatic: imaging for hepatic angiomyolipoma.
Ho CL, Chan WK, Chen S, Leung YL, Cheng TK
J Gastroenterol Hepatol 2010 Sep;25(9):1589. doi: 10.1111/j.1440-1746.2010.06475.x. PMID: 20796161
Hepatic angiomyolipoma: report of changing size and internal composition on follow-up examination in two cases.
Irie H, Honda H, Kuroiwa T, Yoshimitsu K, Tajima T, Jimi M, Shimada M, Taguchi K, Masuda K
J Comput Assist Tomogr 1999 Mar-Apr;23(2):310-3. doi: 10.1097/00004728-199903000-00025. PMID: 10096344

Clinical prediction guides

Fat-Poor Hepatic Angiomyolipoma in Noncirrhotic Livers: Imaging Features, Pathology, and Differential Diagnosis.
Jiang T, Hu Y, Wang J, Li W
J Comput Assist Tomogr 2024 Sep-Oct 01;48(5):727-733. Epub 2024 Apr 10 doi: 10.1097/RCT.0000000000001605. PMID: 38595141
Differentiation between hepatic angiomyolipoma and hepatocellular carcinoma in individuals who are not at-risk for hepatocellular carcinoma.
Park S, Kim MJ, Han K, Park JH, Han DH, Park YN, Kim J, Rhee H
Eur J Radiol 2023 Sep;166:110957. Epub 2023 Jul 6 doi: 10.1016/j.ejrad.2023.110957. PMID: 37451136
CD68-Positive Cells in Hepatic Angiomyolipoma.
Tochio H, Tamaki E, Imai Y, Iwasaki N, Minowa K, Chung H, Suginoshita Y, Inokuma T, Kudo M
Oncology 2017;92 Suppl 1:35-39. Epub 2016 Dec 29 doi: 10.1159/000451013. PMID: 28030864
Education and Imaging. Hepatobiliary and pancreatic: imaging for hepatic angiomyolipoma.
Ho CL, Chan WK, Chen S, Leung YL, Cheng TK
J Gastroenterol Hepatol 2010 Sep;25(9):1589. doi: 10.1111/j.1440-1746.2010.06475.x. PMID: 20796161
Hepatic angiomyolipoma: a clinical experience in diagnosis and treatment.
Zeng JP, Dong JH, Zhang WZ, Wang J, Pang XP
Dig Dis Sci 2010 Nov;55(11):3235-40. Epub 2010 Feb 18 doi: 10.1007/s10620-010-1144-2. PMID: 20165978

Recent systematic reviews

Management of hepatic angiomyolipoma: A systematic review.
Klompenhouwer AJ, Verver D, Janki S, Bramer WM, Doukas M, Dwarkasing RS, de Man RA, IJzermans JNM
Liver Int 2017 Sep;37(9):1272-1280. Epub 2017 Mar 6 doi: 10.1111/liv.13381. PMID: 28177188

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...