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Hepatocarcinogenesis

MedGen UID:
268184
Concept ID:
C1512409
Neoplastic Process
Synonym: Liver Carcinogenesis

Definition

The processes which result in cancers in the liver. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHepatocarcinogenesis

Professional guidelines

PubMed

Damaskos C, Garmpis N, Dimitroulis D, Garmpi A, Psilopatis I, Sarantis P, Koustas E, Kanavidis P, Prevezanos D, Kouraklis G, Karamouzis MV, Marinos G, Kontzoglou K, Antoniou EA
Int J Mol Sci 2022 Nov 15;23(22) doi: 10.3390/ijms232214117. PMID: 36430594Free PMC Article
Lo GH
Hepatology 2014 Aug;60(2):763. Epub 2014 Jun 26 doi: 10.1002/hep.27065. PMID: 24700196
Stevenson DE, Walborg EF Jr, Klaunig JE
Prog Clin Biol Res 1995;391:337-45. PMID: 8532726

Recent clinical studies

Etiology

He F, Zhang P, Liu J, Wang R, Kaufman RJ, Yaden BC, Karin M
J Hepatol 2023 Aug;79(2):362-377. Epub 2023 Mar 28 doi: 10.1016/j.jhep.2023.03.016. PMID: 36996941Free PMC Article
Filliol A, Saito Y, Nair A, Dapito DH, Yu LX, Ravichandra A, Bhattacharjee S, Affo S, Fujiwara N, Su H, Sun Q, Savage TM, Wilson-Kanamori JR, Caviglia JM, Chin L, Chen D, Wang X, Caruso S, Kang JK, Amin AD, Wallace S, Dobie R, Yin D, Rodriguez-Fiallos OM, Yin C, Mehal A, Izar B, Friedman RA, Wells RG, Pajvani UB, Hoshida Y, Remotti HE, Arpaia N, Zucman-Rossi J, Karin M, Henderson NC, Tabas I, Schwabe RF
Nature 2022 Oct;610(7931):356-365. Epub 2022 Oct 5 doi: 10.1038/s41586-022-05289-6. PMID: 36198802Free PMC Article
Rizzo GEM, Cabibbo G, Craxì A
Viruses 2022 May 7;14(5) doi: 10.3390/v14050986. PMID: 35632728Free PMC Article
Banini BA, Sanyal AJ
Adv Cancer Res 2021;149:143-169. Epub 2021 Jan 21 doi: 10.1016/bs.acr.2020.11.001. PMID: 33579423
Marengo A, Rosso C, Bugianesi E
Annu Rev Med 2016;67:103-17. Epub 2015 Oct 14 doi: 10.1146/annurev-med-090514-013832. PMID: 26473416

Diagnosis

Xu C, Xu Z, Zhang Y, Evert M, Calvisi DF, Chen X
J Clin Invest 2022 Feb 15;132(4) doi: 10.1172/JCI154515. PMID: 35166233Free PMC Article
D'souza S, Lau KC, Coffin CS, Patel TR
World J Gastroenterol 2020 Oct 14;26(38):5759-5783. doi: 10.3748/wjg.v26.i38.5759. PMID: 33132633Free PMC Article
Narsinh KH, Cui J, Papadatos D, Sirlin CB, Santillan CS
Abdom Radiol (NY) 2018 Jan;43(1):158-168. doi: 10.1007/s00261-017-1409-8. PMID: 29209739
Marengo A, Rosso C, Bugianesi E
Annu Rev Med 2016;67:103-17. Epub 2015 Oct 14 doi: 10.1146/annurev-med-090514-013832. PMID: 26473416
Blechacz B, Mishra L
Recent Results Cancer Res 2013;190:1-20. doi: 10.1007/978-3-642-16037-0_1. PMID: 22941010

Therapy

Li Z, Zhou Y, Jia K, Yang Y, Zhang L, Wang S, Dong Y, Wang M, Li Y, Lu S, Zhang W, Zhang L, Fan Y, Zhang D, Li N, Yu Y, Cao X, Hou J
J Hematol Oncol 2022 Nov 4;15(1):161. doi: 10.1186/s13045-022-01381-6. PMID: 36333807Free PMC Article
Narsinh KH, Cui J, Papadatos D, Sirlin CB, Santillan CS
Abdom Radiol (NY) 2018 Jan;43(1):158-168. doi: 10.1007/s00261-017-1409-8. PMID: 29209739
Vescovo T, Refolo G, Vitagliano G, Fimia GM, Piacentini M
Clin Microbiol Infect 2016 Oct;22(10):853-861. Epub 2016 Jul 28 doi: 10.1016/j.cmi.2016.07.019. PMID: 27476823
Asham EH, Kaseb A, Ghobrial RM
Surg Clin North Am 2013 Dec;93(6):1423-50. doi: 10.1016/j.suc.2013.08.008. PMID: 24206860
Josephs DH, Ross PJ
Br J Hosp Med (Lond) 2010 Aug;71(8):451-6. doi: 10.12968/hmed.2010.71.8.77669. PMID: 20852487

Prognosis

Shah M, Sarkar D
Int J Mol Sci 2024 Jan 2;25(1) doi: 10.3390/ijms25010597. PMID: 38203767Free PMC Article
Padilla J, Osman NM, Bissig-Choisat B, Grimm SL, Qin X, Major AM, Yang L, Lopez-Terrada D, Coarfa C, Li F, Bissig KD, Moore DD, Fu L
J Hepatol 2024 Feb;80(2):282-292. Epub 2023 Oct 27 doi: 10.1016/j.jhep.2023.10.018. PMID: 37890720Free PMC Article
Vucur M, Ghallab A, Schneider AT, Adili A, Cheng M, Castoldi M, Singer MT, Büttner V, Keysberg LS, Küsgens L, Kohlhepp M, Görg B, Gallage S, Barragan Avila JE, Unger K, Kordes C, Leblond AL, Albrecht W, Loosen SH, Lohr C, Jördens MS, Babler A, Hayat S, Schumacher D, Koenen MT, Govaere O, Boekschoten MV, Jörs S, Villacorta-Martin C, Mazzaferro V, Llovet JM, Weiskirchen R, Kather JN, Starlinger P, Trauner M, Luedde M, Heij LR, Neumann UP, Keitel V, Bode JG, Schneider RK, Tacke F, Levkau B, Lammers T, Fluegen G, Alexandrov T, Collins AL, Nelson G, Oakley F, Mann DA, Roderburg C, Longerich T, Weber A, Villanueva A, Samson AL, Murphy JM, Kramann R, Geisler F, Costa IG, Hengstler JG, Heikenwalder M, Luedde T
Immunity 2023 Jul 11;56(7):1578-1595.e8. Epub 2023 Jun 16 doi: 10.1016/j.immuni.2023.05.017. PMID: 37329888
Blechacz B, Mishra L
Recent Results Cancer Res 2013;190:1-20. doi: 10.1007/978-3-642-16037-0_1. PMID: 22941010
El-Serag HB, Rudolph KL
Gastroenterology 2007 Jun;132(7):2557-76. doi: 10.1053/j.gastro.2007.04.061. PMID: 17570226

Clinical prediction guides

Padilla J, Osman NM, Bissig-Choisat B, Grimm SL, Qin X, Major AM, Yang L, Lopez-Terrada D, Coarfa C, Li F, Bissig KD, Moore DD, Fu L
J Hepatol 2024 Feb;80(2):282-292. Epub 2023 Oct 27 doi: 10.1016/j.jhep.2023.10.018. PMID: 37890720Free PMC Article
Sun J, Ding J, Shen Q, Wang X, Wang M, Huang Y, Zhang X, Zhu H, Zhang F, Wu D, Peng M, Zhang Z, Yuan Y, Li W, She ZG, Zhang XJ, Li H, Zhang P, Huang Z
J Hepatol 2023 Mar;78(3):627-642. Epub 2022 Dec 1 doi: 10.1016/j.jhep.2022.11.017. PMID: 36462680
Zhan X, Wu R, Kong XH, You Y, He K, Sun XY, Huang Y, Chen WX, Duan L
Cancer Commun (Lond) 2023 Feb;43(2):225-245. Epub 2022 Nov 8 doi: 10.1002/cac2.12388. PMID: 36346061Free PMC Article
Feng GS
Cancer Cell 2012 Feb 14;21(2):150-4. doi: 10.1016/j.ccr.2012.01.001. PMID: 22340589Free PMC Article
Feitelson MA, Sun B, Satiroglu Tufan NL, Liu J, Pan J, Lian Z
Oncogene 2002 Apr 11;21(16):2593-604. doi: 10.1038/sj.onc.1205434. PMID: 11971194

Recent systematic reviews

Damaskos C, Garmpis N, Dimitroulis D, Garmpi A, Psilopatis I, Sarantis P, Koustas E, Kanavidis P, Prevezanos D, Kouraklis G, Karamouzis MV, Marinos G, Kontzoglou K, Antoniou EA
Int J Mol Sci 2022 Nov 15;23(22) doi: 10.3390/ijms232214117. PMID: 36430594Free PMC Article
Yao M, Sai W, Zheng W, Wang L, Dong Z, Yao D
Curr Med Chem 2020;27(20):3290-3301. doi: 10.2174/0929867326666190624161158. PMID: 31232234
Huang P, Liu M, Zang F, Yao Y, Yue M, Wang J, Fan H, Zhuo L, Wu J, Xia X, Feng Y, Yu R
Carcinogenesis 2018 Dec 31;39(12):1497-1505. doi: 10.1093/carcin/bgy099. PMID: 30602007
Hu X, Jiang J, Xu Q, Ni C, Yang L, Huang D
Biomed Res Int 2018;2018:8126208. Epub 2018 Jul 9 doi: 10.1155/2018/8126208. PMID: 30105249Free PMC Article
Zoller H, Tilg H
Metabolism 2016 Aug;65(8):1151-60. Epub 2016 Jan 23 doi: 10.1016/j.metabol.2016.01.010. PMID: 26907206

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