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Breast leiomyoma

MedGen UID:
267768
•Concept ID:
C1511317
•
Neoplastic Process
Synonyms: Breast Leiomyoma; breast leiomyoma; leiomyoma of breast
 
Monarch Initiative: MONDO:0002057

Definition

A well-circumscribed benign smooth muscle neoplasm arising from the breast. It is characterized by the presence of spindle cells with cigar-shaped nuclei, interlacing fascicles, and a whorled pattern. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBreast leiomyoma

Professional guidelines

PubMed

Infertility: Evaluation and Management.
Phillips K, Olanrewaju RA, Omole F
Am Fam Physician 2023 Jun;107(6):623-630. PMID: 37327165
Differential Diagnosis of Benign Spindle Cell Lesions.
Magro G
Surg Pathol Clin 2018 Mar;11(1):91-121. Epub 2017 Dec 9 doi: 10.1016/j.path.2017.09.005. PMID: 29413661
EMAS position statement: management of uterine fibroids.
Pérez-López FR, Ornat L, Ceausu I, Depypere H, Erel CT, Lambrinoudaki I, Schenck-Gustafsson K, Simoncini T, Tremollieres F, Rees M; EMAS
Maturitas 2014 Sep;79(1):106-16. Epub 2014 Jun 9 doi: 10.1016/j.maturitas.2014.06.002. PMID: 24975954

Recent clinical studies

Diagnosis

Intraparenchymal breast leiomyoma and atypical leiomyoma.
Long M, Hu XL, Zhao G, Liu Y, Hu T
BMC Womens Health 2022 Apr 14;22(1):119. doi: 10.1186/s12905-022-01700-6. PMID: 35421983Free PMC Article
Leiomyoma of the breast parenchyma: a case report and review of the literature.
Brandão RG, Elias S, Pinto Nazário AC, Alcoforado Assunção MDCG, Esposito Papa CC, Facina G
Sao Paulo Med J 2018 Mar-Apr;136(2):177-181. Epub 2017 Sep 18 doi: 10.1590/1516-3180.2016.0253040117. PMID: 28977094Free PMC Article
Nipple inversion caused by a breast leiomyoma.
Wang H, Luo B, Li F
Breast J 2012 Jul-Aug;18(4):376-7. Epub 2012 May 23 doi: 10.1111/j.1524-4741.2012.01262.x. PMID: 22616738
Parenchymal leiomyoma of the breast. Report of a case and clinicopathological review.
Tamir G, Yampolsky I, Sandbank J
Eur J Surg Oncol 1995 Feb;21(1):88-9. doi: 10.1016/s0748-7983(05)80077-0. PMID: 7851564

Prognosis

Intraparenchymal breast leiomyoma and atypical leiomyoma.
Long M, Hu XL, Zhao G, Liu Y, Hu T
BMC Womens Health 2022 Apr 14;22(1):119. doi: 10.1186/s12905-022-01700-6. PMID: 35421983Free PMC Article

Clinical prediction guides

Leiomyoma of the breast parenchyma: a case report and review of the literature.
Brandão RG, Elias S, Pinto Nazário AC, Alcoforado Assunção MDCG, Esposito Papa CC, Facina G
Sao Paulo Med J 2018 Mar-Apr;136(2):177-181. Epub 2017 Sep 18 doi: 10.1590/1516-3180.2016.0253040117. PMID: 28977094Free PMC Article

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