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Retrograde amnesia

MedGen UID:
264
•Concept ID:
C0002624
•
Mental or Behavioral Dysfunction
Synonyms: Amnesia, Retrograde; Amnesias, Retrograde; Retrograde Amnesia; Retrograde Amnesias
SNOMED CT: RA - Retrograde amnesia (51921000); Retrograde amnesia (51921000)
 
HPO: HP:0033690
Monarch Initiative: MONDO:0003040

Definition

Inability to retrieve information from the long-term memory that was acquired before the onset of amnesia. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRetrograde amnesia

Professional guidelines

PubMed

Effects of magnetic seizure therapy on anterograde and retrograde amnesia in treatment-resistant depression.
Kayser S, Bewernick BH, Wagner S, Schlaepfer TE
Depress Anxiety 2020 Feb;37(2):125-133. Epub 2019 Nov 4 doi: 10.1002/da.22958. PMID: 31682325
Differential diagnosis between 'unexplained' fall and syncopal fall: a difficult or impossible task.
Alboni P, Coppola P, Stucci N, Tsakiridu V
J Cardiovasc Med (Hagerstown) 2015 Feb;16(2):82-9. doi: 10.2459/JCM.0000000000000076. PMID: 24838038
Results of learning experiments in the course of treatment of endogenomorphic depression. A comparison of electroconvulsive and pharmacological treatment.
Schuster P, Opgenoorth E, Gabriel E, Presslich O, Sowinetz B
Psychopathology 1986;19(3):116-30. doi: 10.1159/000284437. PMID: 3737823

Recent clinical studies

Etiology

Digital dementia in the internet generation: excessive screen time during brain development will increase the risk of Alzheimer's disease and related dementias in adulthood.
Manwell LA, Tadros M, Ciccarelli TM, Eikelboom R
J Integr Neurosci 2022 Jan 28;21(1):28. doi: 10.31083/j.jin2101028. PMID: 35164464
Transient Global Amnesia.
Sealy D, Tiller RJ, Johnson K
Am Fam Physician 2022 Jan 1;105(1):50-54. PMID: 35029951
Adverse Effects of Electroconvulsive Therapy.
Andrade C, Arumugham SS, Thirthalli J
Psychiatr Clin North Am 2016 Sep;39(3):513-30. Epub 2016 Jun 25 doi: 10.1016/j.psc.2016.04.004. PMID: 27514303
Adolescent sports concussion.
Reddy CC, Collins MW, Gioia GA
Phys Med Rehabil Clin N Am 2008 May;19(2):247-69, viii. doi: 10.1016/j.pmr.2007.12.002. PMID: 18395647
Sports-related concussions.
Poirier MP, Wadsworth MR
Pediatr Emerg Care 2000 Aug;16(4):278-83; quiz 284-6. doi: 10.1097/00006565-200008000-00018. PMID: 10966352

Diagnosis

Acute-onset amnesia: transient global amnesia and other causes.
Miller TD, Butler CR
Pract Neurol 2022 Jun;22(3):201-208. Epub 2022 May 3 doi: 10.1136/practneurol-2020-002826. PMID: 35504698
Sleep Terrors: An Updated Review.
Leung AKC, Leung AAM, Wong AHC, Hon KL
Curr Pediatr Rev 2020;16(3):176-182. doi: 10.2174/1573396315666191014152136. PMID: 31612833Free PMC Article
Adverse Effects of Electroconvulsive Therapy.
Andrade C, Arumugham SS, Thirthalli J
Psychiatr Clin North Am 2016 Sep;39(3):513-30. Epub 2016 Jun 25 doi: 10.1016/j.psc.2016.04.004. PMID: 27514303
Adolescent sports concussion.
Reddy CC, Collins MW, Gioia GA
Phys Med Rehabil Clin N Am 2008 May;19(2):247-69, viii. doi: 10.1016/j.pmr.2007.12.002. PMID: 18395647
Sports-related concussions.
Poirier MP, Wadsworth MR
Pediatr Emerg Care 2000 Aug;16(4):278-83; quiz 284-6. doi: 10.1097/00006565-200008000-00018. PMID: 10966352

Therapy

Sleep Terrors: An Updated Review.
Leung AKC, Leung AAM, Wong AHC, Hon KL
Curr Pediatr Rev 2020;16(3):176-182. doi: 10.2174/1573396315666191014152136. PMID: 31612833Free PMC Article
Adverse Effects of Electroconvulsive Therapy.
Andrade C, Arumugham SS, Thirthalli J
Psychiatr Clin North Am 2016 Sep;39(3):513-30. Epub 2016 Jun 25 doi: 10.1016/j.psc.2016.04.004. PMID: 27514303
Resolution of delusional depression after recovery from delirium.
Ueki H, Ogawa N
Compr Psychiatry 2004 May-Jun;45(3):230-4. doi: 10.1016/j.comppsych.2003.12.009. PMID: 15124155
Retrograde amnesia and bilateral electroconvulsive therapy. Long-term follow-up.
Squire LR, Slater PC, Miller PL
Arch Gen Psychiatry 1981 Jan;38(1):89-95. doi: 10.1001/archpsyc.1981.01780260091010. PMID: 7458573
Poriomania.
Mayeux R, Alexander MP, Benson DF, Brandt J, Rosen J
Neurology 1979 Dec;29(12):1616-9. doi: 10.1212/wnl.29.12.1616. PMID: 574226

Prognosis

Acute-onset amnesia: transient global amnesia and other causes.
Miller TD, Butler CR
Pract Neurol 2022 Jun;22(3):201-208. Epub 2022 May 3 doi: 10.1136/practneurol-2020-002826. PMID: 35504698
Digital dementia in the internet generation: excessive screen time during brain development will increase the risk of Alzheimer's disease and related dementias in adulthood.
Manwell LA, Tadros M, Ciccarelli TM, Eikelboom R
J Integr Neurosci 2022 Jan 28;21(1):28. doi: 10.31083/j.jin2101028. PMID: 35164464
Sleep Terrors: An Updated Review.
Leung AKC, Leung AAM, Wong AHC, Hon KL
Curr Pediatr Rev 2020;16(3):176-182. doi: 10.2174/1573396315666191014152136. PMID: 31612833Free PMC Article
Transient global amnesia.
Marazzi C, Scoditti U, Ticinesi A, Nouvenne A, Pigna F, Guida L, Morelli I, Borghi L, Meschi T
Acta Biomed 2014 Dec 17;85(3):229-35. PMID: 25567459
Amnesic disorders.
Markowitsch HJ, Staniloiu A
Lancet 2012 Oct 20;380(9851):1429-40. Epub 2012 Apr 13 doi: 10.1016/S0140-6736(11)61304-4. PMID: 22503117

Clinical prediction guides

Digital dementia in the internet generation: excessive screen time during brain development will increase the risk of Alzheimer's disease and related dementias in adulthood.
Manwell LA, Tadros M, Ciccarelli TM, Eikelboom R
J Integr Neurosci 2022 Jan 28;21(1):28. doi: 10.31083/j.jin2101028. PMID: 35164464
Sleep Terrors: An Updated Review.
Leung AKC, Leung AAM, Wong AHC, Hon KL
Curr Pediatr Rev 2020;16(3):176-182. doi: 10.2174/1573396315666191014152136. PMID: 31612833Free PMC Article
Remembering to attend: the anterior cingulate cortex and remote memory.
Weible AP
Behav Brain Res 2013 May 15;245:63-75. Epub 2013 Feb 20 doi: 10.1016/j.bbr.2013.02.010. PMID: 23453992
Resolution of delusional depression after recovery from delirium.
Ueki H, Ogawa N
Compr Psychiatry 2004 May-Jun;45(3):230-4. doi: 10.1016/j.comppsych.2003.12.009. PMID: 15124155
Retrograde amnesia.
Squire LR, Clark RE, Knowlton BJ
Hippocampus 2001;11(1):50-5. doi: 10.1002/1098-1063(2001)11:1<50::AID-HIPO1019>3.0.CO;2-G. PMID: 11261772

Recent systematic reviews

Cognitive deficits and course of recovery in transient global amnesia: a systematic review.
Liampas I, Kyriakoulopoulou P, Akrioti A, Stamati P, Germeni A, Batzikosta P, Tsiamaki E, Veltsista D, Kefalopoulou Z, Siokas V, Chroni E, Dardiotis E
J Neurol 2024 Oct;271(10):6401-6425. Epub 2024 Aug 1 doi: 10.1007/s00415-024-12563-2. PMID: 39090229
Posttraumatic Amnesia: A Systematic Review and Meta-Analysis. Proposal for a New Severity Classification.
Vile AR, Jang K, Gourlay D, Marshman LAG
World Neurosurg 2022 Jun;162:e369-e393. Epub 2022 Mar 11 doi: 10.1016/j.wneu.2022.03.018. PMID: 35288355
Using a Likelihood Heuristic to Summarize Conflicting Literature on Predictors of Clinical Outcome Following Sport-Related Concussion.
Büttner F, Terry DP, Iverson GL
Clin J Sport Med 2021 Nov 1;31(6):e476-e483. doi: 10.1097/JSM.0000000000000825. PMID: 32941376
What is the level of evidence for the amnestic effects of sedatives in pediatric patients? A systematic review and meta-analyses.
Viana KA, Daher A, Maia LC, Costa PS, Martins CC, Paiva SM, Costa LR
PLoS One 2017;12(7):e0180248. Epub 2017 Jul 7 doi: 10.1371/journal.pone.0180248. PMID: 28686702Free PMC Article
Objective cognitive performance associated with electroconvulsive therapy for depression: a systematic review and meta-analysis.
Semkovska M, McLoughlin DM
Biol Psychiatry 2010 Sep 15;68(6):568-77. Epub 2010 Jul 31 doi: 10.1016/j.biopsych.2010.06.009. PMID: 20673880

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