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Lung hilum carcinoma

MedGen UID:
235266
•Concept ID:
C1334445
•
Neoplastic Process
Synonyms: carcinoma of lung hilus; Hilar Lung Carcinoma; hilar lung carcinoma; Lung Hilum Carcinoma; lung hilum carcinoma; lung hilus carcinoma
 
Monarch Initiative: MONDO:0004499

Definition

A lung carcinoma arising from the hilum of the lung. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLung hilum carcinoma

Professional guidelines

PubMed

Low-dose hilar and mediastinal stereotactic body radiation therapy for non-small cell lung cancer: Analysis of outcomes in patients receiving one or multiple courses of treatment.
Kowalchuk RO, Waters MR, Richardson M, Spencer K, Larner JM, Kersh CR
Thorac Cancer 2020 Jul;11(7):2005-2013. Epub 2020 May 29 doi: 10.1111/1759-7714.13501. PMID: 32469465Free PMC Article
Salvage treatment of NSCLC recurrence after first-line chemotherapy failure: Iodine-125 seed brachytherapy or microwave ablation?
Liu B, Wang Y, Tian S, Hertzanu Y, Zhao X, Li Y
Thorac Cancer 2020 Mar;11(3):697-703. Epub 2020 Jan 29 doi: 10.1111/1759-7714.13320. PMID: 31995853Free PMC Article
Microwave ablation therapy: clinical utility in treatment of pulmonary metastases.
Vogl TJ, Naguib NN, Gruber-Rouh T, Koitka K, Lehnert T, Nour-Eldin NE
Radiology 2011 Nov;261(2):643-51. doi: 10.1148/radiol.11101643. PMID: 22012906

Recent clinical studies

Etiology

Detection of pleural lymph flow using indocyanine green fluorescence imaging in non-small cell lung cancer surgery: a preliminary study.
Imai K, Minamiya Y, Saito H, Nakagawa T, Ito M, Ono T, Motoyama S, Sato Y, Konno H, Ogawa J
Surg Today 2013 Mar;43(3):249-54. Epub 2012 Jun 23 doi: 10.1007/s00595-012-0237-2. PMID: 22729459
Margin and local recurrence after sublobar resection of non-small cell lung cancer.
El-Sherif A, Fernando HC, Santos R, Pettiford B, Luketich JD, Close JM, Landreneau RJ
Ann Surg Oncol 2007 Aug;14(8):2400-5. Epub 2007 May 16 doi: 10.1245/s10434-007-9421-9. PMID: 17505859
Video-assisted lobectomy in the elderly.
Asamura H, Nakayama H, Kondo H, Tsuchiya R, Naruke T
Chest 1997 Apr;111(4):1101-5. doi: 10.1378/chest.111.4.1101. PMID: 9106593
Preoperative paclitaxel plus carboplatin for patients with intermediate-risk non-small cell lung cancer.
Ruckdeschel JC
Semin Oncol 1996 Dec;23(6 Suppl 16):62-7. PMID: 9007125
Selective mediastinoscopy.
Acosta JL, Manfredi F
Chest 1977 Feb;71(2):150-4. doi: 10.1378/chest.71.2.150. PMID: 832484

Diagnosis

Mechanical thrombectomy for repeated cerebral tumor embolism from a thoracic sarcomatoid carcinoma.
Pop R, Mihoc D, Manisor M, Richter JS, Lindner V, Janssen-Langenstein R, Simu M, Wolff V, Beaujeux R
BMJ Case Rep 2017 Aug 11;2017 doi: 10.1136/bcr-2017-013092. PMID: 28801324Free PMC Article
Pulmonary lymphoepithelioma-like carcinoma with rapid progression.
Tanaka S, Chen F, Date H
Gen Thorac Cardiovasc Surg 2012 Mar;60(3):164-7. Epub 2012 Mar 15 doi: 10.1007/s11748-011-0789-x. PMID: 22419187
Video-assisted lobectomy in the elderly.
Asamura H, Nakayama H, Kondo H, Tsuchiya R, Naruke T
Chest 1997 Apr;111(4):1101-5. doi: 10.1378/chest.111.4.1101. PMID: 9106593
Lymphocytic lymphoma with associated gamma heavy chain and IgM-lambda paraproteins. An unusual biclonal gammopathy.
Presti BC, Sciotto CG, Marsh SG
Am J Clin Pathol 1990 Jan;93(1):137-41. doi: 10.1093/ajcp/93.1.137. PMID: 2104738
Carcinomatous involvement of the hilum and mediastinum: computed tomographic and magnetic resonance evaluation.
Heelan RT, Martini N, Westcott JW, Bains MS, Watson RC, Caravelli JF, Berkmen YM, Henschke CI, McCormack PM, McCaughan BC
Radiology 1985 Jul;156(1):111-5. doi: 10.1148/radiology.156.1.4001396. PMID: 4001396

Therapy

Complete Response of Locally Advanced Lung Adenocarcinoma Following Basil Combined With Cisplatin Plus Pemetrexed Chemotherapy: A Case Report.
He C, Li L, Feng B, Xie L, Zhang L, Liu B
Integr Cancer Ther 2024 Jan-Dec;23:15347354241295269. doi: 10.1177/15347354241295269. PMID: 39511726Free PMC Article
Hyperprogression after pembrolizumab treatment in two patients with metastatic urothelial carcinoma.
Hatano T, Matsu-Ura T, Mori KI, Inaba H, Endo K, Tamari M, Egawa S
Jpn J Clin Oncol 2019 May 1;49(5):473-476. doi: 10.1093/jjco/hyz038. PMID: 30920617
Sequential robotic-assisted lung resection with a subxiphoid utility incision.
Slight RD, Koulaxouzidis G, Stamenkovic S
Asian Cardiovasc Thorac Ann 2018 Jun;26(5):404-406. Epub 2018 May 9 doi: 10.1177/0218492318776890. PMID: 29742905
Mechanical thrombectomy for repeated cerebral tumor embolism from a thoracic sarcomatoid carcinoma.
Pop R, Mihoc D, Manisor M, Richter JS, Lindner V, Janssen-Langenstein R, Simu M, Wolff V, Beaujeux R
BMJ Case Rep 2017 Aug 11;2017 doi: 10.1136/bcr-2017-013092. PMID: 28801324Free PMC Article
Segmentectomy for c-T1N0M0 non-small cell lung cancer.
Nomori H
Surg Today 2014 May;44(5):812-9. Epub 2013 Jun 29 doi: 10.1007/s00595-013-0649-7. PMID: 23812915

Prognosis

Hyperprogression after pembrolizumab treatment in two patients with metastatic urothelial carcinoma.
Hatano T, Matsu-Ura T, Mori KI, Inaba H, Endo K, Tamari M, Egawa S
Jpn J Clin Oncol 2019 May 1;49(5):473-476. doi: 10.1093/jjco/hyz038. PMID: 30920617
Mechanical thrombectomy for repeated cerebral tumor embolism from a thoracic sarcomatoid carcinoma.
Pop R, Mihoc D, Manisor M, Richter JS, Lindner V, Janssen-Langenstein R, Simu M, Wolff V, Beaujeux R
BMJ Case Rep 2017 Aug 11;2017 doi: 10.1136/bcr-2017-013092. PMID: 28801324Free PMC Article
Robotic Assisted Extended Sleeve Lobectomy After Neoadjuvant Chemotherapy.
Pan X, Chen Y, Shi J, Zhao H, Chen H
Ann Thorac Surg 2015 Dec;100(6):e129-31. doi: 10.1016/j.athoracsur.2015.08.084. PMID: 26652569
Pulmonary lymphoepithelioma-like carcinoma with rapid progression.
Tanaka S, Chen F, Date H
Gen Thorac Cardiovasc Surg 2012 Mar;60(3):164-7. Epub 2012 Mar 15 doi: 10.1007/s11748-011-0789-x. PMID: 22419187
CT of the pulmonary hilum.
Chiles C
Radiol Clin North Am 1990 May;28(3):539-53. PMID: 2183263

Clinical prediction guides

Staple Line Thickening After Sublobar Resection: Reaction or Recurrence?
Sun B, Kamel MK, Nasar A, Harrison S, Lee B, Port JL, Altorki NK, Stiles BM
Ann Thorac Surg 2020 Jun;109(6):1670-1676. Epub 2020 Feb 11 doi: 10.1016/j.athoracsur.2019.12.065. PMID: 32057814
Relationship between the Size and Location of the Mass and Hilar and Mediastinal Lymph Node Metastasis in Early and Locally Advanced Non-small Cell Lung Cancer.
Kuzucuoglu M, Gokyer A, Kula O, Yekdes AC, Sunal BS, Karamustafaoglu YA, Yoruk Y, Cicin I
J Coll Physicians Surg Pak 2020 Feb;30(2):172-176. doi: 10.29271/jcpsp.2020.02.172. PMID: 32036826
Adenocarcinoma of the Rete Testis: Clinicopathologic and Immunohistochemical Characterization of 6 Cases and Review of the Literature.
Al-Obaidy KI, Idrees MT, Grignon DJ, Ulbright TM
Am J Surg Pathol 2019 May;43(5):670-681. doi: 10.1097/PAS.0000000000001219. PMID: 30676333
Sequential multimodality bronchoscopic investigation of peripheral pulmonary lesions.
Steinfort DP, Bonney A, See K, Irving LB
Eur Respir J 2016 Feb;47(2):607-14. Epub 2015 Nov 5 doi: 10.1183/13993003.00786-2015. PMID: 26541529
CT of the pulmonary hilum.
Chiles C
Radiol Clin North Am 1990 May;28(3):539-53. PMID: 2183263

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