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Gastric pylorus carcinoma

MedGen UID:
234301
•Concept ID:
C1333787
•
Neoplastic Process
Synonyms: Cancer of Gastric Pylorus; cancer of gastric pylorus; Cancer of Pylorus of Stomach; cancer of pylorus of stomach; Cancer of the Gastric Pylorus; cancer of the gastric pylorus; Cancer of the Pylorus of the Stomach; cancer of the pylorus of the stomach; Carcinoma of Gastric Pylorus; carcinoma of gastric pylorus; Carcinoma of Pylorus of Stomach; carcinoma of pylorus of stomach; Carcinoma of the Gastric Pylorus; carcinoma of the gastric pylorus; Carcinoma of the Pylorus of the Stomach; carcinoma of the pylorus of the stomach; gastric pylorus (stomach) cancer; Gastric Pylorus Cancer; gastric pylorus cancer; Gastric Pylorus Carcinoma; gastric pylorus carcinoma
 
Monarch Initiative: MONDO:0003971

Definition

A carcinoma that arises from the pylorus. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGastric pylorus carcinoma

Professional guidelines

PubMed

Emerging evidence supports grouping by location of early gastric carcinoma for appropriate clinical management in Chinese patients.
Huang Q, Li R, Xu GF, Zhou D, Fan XS, Zou XP
J Dig Dis 2018 Dec;19(12):730-736. Epub 2018 Nov 14 doi: 10.1111/1751-2980.12674. PMID: 30270559
Esophagogastric cancers secondary to a breast primary tumor do not require resection.
Ayantunde AA, Agrawal A, Parsons SL, Welch NT
World J Surg 2007 Aug;31(8):1597-601. doi: 10.1007/s00268-007-9099-y. PMID: 17578645
Clinical presentation, endoscopic features, and treatment of gastric metastases from breast carcinoma.
Taal BG, Peterse H, Boot H
Cancer 2000 Dec 1;89(11):2214-21. PMID: 11147591

Recent clinical studies

Etiology

Complications After Endoscopic Stenting for Malignant Gastric Outlet Obstruction: A Cohort Study.
Sterpetti AV, Fiori E, Sapienza P, Lamazza A
Surg Laparosc Endosc Percutan Tech 2019 Jun;29(3):169-172. doi: 10.1097/SLE.0000000000000656. PMID: 30855401
Are There Indications for Total Pancreatectomy in 2016?
Andrén-Sandberg Å, Ansorge C, Yadav TD
Dig Surg 2016;33(4):329-34. Epub 2016 May 25 doi: 10.1159/000445018. PMID: 27215746
Hospital costs of complications after a pancreatoduodenectomy.
Santema TB, Visser A, Busch OR, Dijkgraaf MG, Goslings JC, Gouma DJ, Ubbink DT
HPB (Oxford) 2015 Aug;17(8):723-31. Epub 2015 Jun 17 doi: 10.1111/hpb.12440. PMID: 26082095Free PMC Article
Small undifferentiated intramucosal gastric cancer with lymph-node metastasis: case report.
Odagaki T, Suzuki H, Oda I, Yoshinaga S, Nonaka S, Katai H, Taniguchi H, Kushima R, Saito Y
World J Gastroenterol 2013 May 28;19(20):3157-60. doi: 10.3748/wjg.v19.i20.3157. PMID: 23716998Free PMC Article
Long-term investigations after pyloromyotomy for infantile pyloric stenosis.
Dietl KH, Borowski U, Menzel J, Wissing C, Senninger N, Brockmann J
Eur J Pediatr Surg 2000 Dec;10(6):365-7. doi: 10.1055/s-2008-1072392. PMID: 11215776

Diagnosis

Incipient Intracholecystic Papillary Neoplasm of the Gallbladder Without Dysplasia.
Lim JS, Dominguez A, Kidd N, Mudaliar K, Buell JF, Jeyarajah DR, Osman H
Am Surg 2024 Nov;90(11):3131-3133. Epub 2024 May 28 doi: 10.1177/00031348241257466. PMID: 38807267
Multiple neuroendocrine tumors in the stomach, duodenum and pancreas of a MEN1 patient.
Wang S, Zhang W, Xu M, Xia M
Rev Esp Enferm Dig 2024 Jun;116(6):339-341. doi: 10.17235/reed.2023.9756/2023. PMID: 37350653
Ectopic pancreatitis.
Hoven N, Spilseth B
Minn Med 2014 Oct;97(10):36-7. PMID: 25651633
Small undifferentiated intramucosal gastric cancer with lymph-node metastasis: case report.
Odagaki T, Suzuki H, Oda I, Yoshinaga S, Nonaka S, Katai H, Taniguchi H, Kushima R, Saito Y
World J Gastroenterol 2013 May 28;19(20):3157-60. doi: 10.3748/wjg.v19.i20.3157. PMID: 23716998Free PMC Article
Adenocarcinoma of the duodenum.
Sarma DP, Weilbaecher TG
J Surg Oncol 1987 Apr;34(4):262-3. doi: 10.1002/jso.2930340410. PMID: 3560962

Therapy

Complications After Endoscopic Stenting for Malignant Gastric Outlet Obstruction: A Cohort Study.
Sterpetti AV, Fiori E, Sapienza P, Lamazza A
Surg Laparosc Endosc Percutan Tech 2019 Jun;29(3):169-172. doi: 10.1097/SLE.0000000000000656. PMID: 30855401
Are There Indications for Total Pancreatectomy in 2016?
Andrén-Sandberg Å, Ansorge C, Yadav TD
Dig Surg 2016;33(4):329-34. Epub 2016 May 25 doi: 10.1159/000445018. PMID: 27215746
Hospital costs of complications after a pancreatoduodenectomy.
Santema TB, Visser A, Busch OR, Dijkgraaf MG, Goslings JC, Gouma DJ, Ubbink DT
HPB (Oxford) 2015 Aug;17(8):723-31. Epub 2015 Jun 17 doi: 10.1111/hpb.12440. PMID: 26082095Free PMC Article
Pylorus-preserving versus pylorus-resecting pancreaticoduodenectomy for periampullary and pancreatic carcinoma: a meta-analysis.
Yang C, Wu HS, Chen XL, Wang CY, Gou SM, Xiao J, He ZQ, Chen QJ, Li YF
PLoS One 2014;9(3):e90316. Epub 2014 Mar 6 doi: 10.1371/journal.pone.0090316. PMID: 24603478Free PMC Article
Delayed gastric emptying is associated with pylorus-preserving but not classical Whipple pancreaticoduodenectomy: a review of the literature and critical reappraisal of the implicated pathomechanism.
Paraskevas KI, Avgerinos C, Manes C, Lytras D, Dervenis C
World J Gastroenterol 2006 Oct 7;12(37):5951-8. doi: 10.3748/wjg.v12.i37.5951. PMID: 17009392Free PMC Article

Prognosis

Counter-Clockwise Approach for Robotic Pylorus-Preserving Pancreatoduodenectomy.
Araujo RLC, Coelho TRV, Milani JM
J Gastrointest Surg 2022 Dec;26(12):2620-2622. Epub 2022 Aug 24 doi: 10.1007/s11605-022-05439-1. PMID: 36002786
Complications After Endoscopic Stenting for Malignant Gastric Outlet Obstruction: A Cohort Study.
Sterpetti AV, Fiori E, Sapienza P, Lamazza A
Surg Laparosc Endosc Percutan Tech 2019 Jun;29(3):169-172. doi: 10.1097/SLE.0000000000000656. PMID: 30855401
Small undifferentiated intramucosal gastric cancer with lymph-node metastasis: case report.
Odagaki T, Suzuki H, Oda I, Yoshinaga S, Nonaka S, Katai H, Taniguchi H, Kushima R, Saito Y
World J Gastroenterol 2013 May 28;19(20):3157-60. doi: 10.3748/wjg.v19.i20.3157. PMID: 23716998Free PMC Article
Long-term investigations after pyloromyotomy for infantile pyloric stenosis.
Dietl KH, Borowski U, Menzel J, Wissing C, Senninger N, Brockmann J
Eur J Pediatr Surg 2000 Dec;10(6):365-7. doi: 10.1055/s-2008-1072392. PMID: 11215776
Cloning and expression of a human gene encoding an N-acetylgalactosamine-alpha2,6-sialyltransferase (ST6GalNAc I): a candidate for synthesis of cancer-associated sialyl-Tn antigens.
Ikehara Y, Kojima N, Kurosawa N, Kudo T, Kono M, Nishihara S, Issiki S, Morozumi K, Itzkowitz S, Tsuda T, Nishimura SI, Tsuji S, Narimatsu H
Glycobiology 1999 Nov;9(11):1213-24. doi: 10.1093/glycob/9.11.1213. PMID: 10536037

Clinical prediction guides

Pathological and oncological outcomes of pylorus-preserving versus conventional distal gastrectomy in early gastric cancer: a systematic review and meta-analysis.
Hou S, Liu F, Gao Z, Ye Y
World J Surg Oncol 2022 Sep 24;20(1):308. doi: 10.1186/s12957-022-02766-0. PMID: 36153587Free PMC Article
Emerging evidence supports grouping by location of early gastric carcinoma for appropriate clinical management in Chinese patients.
Huang Q, Li R, Xu GF, Zhou D, Fan XS, Zou XP
J Dig Dis 2018 Dec;19(12):730-736. Epub 2018 Nov 14 doi: 10.1111/1751-2980.12674. PMID: 30270559
Small undifferentiated intramucosal gastric cancer with lymph-node metastasis: case report.
Odagaki T, Suzuki H, Oda I, Yoshinaga S, Nonaka S, Katai H, Taniguchi H, Kushima R, Saito Y
World J Gastroenterol 2013 May 28;19(20):3157-60. doi: 10.3748/wjg.v19.i20.3157. PMID: 23716998Free PMC Article
Cloning and expression of a human gene encoding an N-acetylgalactosamine-alpha2,6-sialyltransferase (ST6GalNAc I): a candidate for synthesis of cancer-associated sialyl-Tn antigens.
Ikehara Y, Kojima N, Kurosawa N, Kudo T, Kono M, Nishihara S, Issiki S, Morozumi K, Itzkowitz S, Tsuda T, Nishimura SI, Tsuji S, Narimatsu H
Glycobiology 1999 Nov;9(11):1213-24. doi: 10.1093/glycob/9.11.1213. PMID: 10536037
Preservation of the pylorus in pancreaticoduodenectomy.
Traverso LW, Longmire WP Jr
Surg Gynecol Obstet 1978 Jun;146(6):959-62. PMID: 653575

Recent systematic reviews

Pathological and oncological outcomes of pylorus-preserving versus conventional distal gastrectomy in early gastric cancer: a systematic review and meta-analysis.
Hou S, Liu F, Gao Z, Ye Y
World J Surg Oncol 2022 Sep 24;20(1):308. doi: 10.1186/s12957-022-02766-0. PMID: 36153587Free PMC Article
Pylorus-preserving pancreaticoduodenectomy (pp Whipple) versus pancreaticoduodenectomy (classic Whipple) for surgical treatment of periampullary and pancreatic carcinoma.
Hüttner FJ, Fitzmaurice C, Schwarzer G, Seiler CM, Antes G, Büchler MW, Diener MK
Cochrane Database Syst Rev 2016 Feb 16;2(2):CD006053. doi: 10.1002/14651858.CD006053.pub6. PMID: 26905229Free PMC Article
Pylorus-preserving pancreaticoduodenectomy (pp Whipple) versus pancreaticoduodenectomy (classic Whipple) for surgical treatment of periampullary and pancreatic carcinoma.
Diener MK, Fitzmaurice C, Schwarzer G, Seiler CM, Hüttner FJ, Antes G, Knaebel HP, Büchler MW
Cochrane Database Syst Rev 2014 Nov 11;11(11):CD006053. doi: 10.1002/14651858.CD006053.pub5. PMID: 25387229Free PMC Article
Endoscopic stenting for gastric outlet obstruction in patients with unresectable antro pyloric cancer. Systematic review of the literature and final results of a prospective study. The point of view of a surgical group.
Fiori E, Lamazza A, Demasi E, Decesare A, Schillaci A, Sterpetti AV
Am J Surg 2013 Aug;206(2):210-7. Epub 2013 Jun 2 doi: 10.1016/j.amjsurg.2012.08.018. PMID: 23735668
A systematic review and meta-analysis of pylorus-preserving versus classical pancreaticoduodenectomy for surgical treatment of periampullary and pancreatic carcinoma.
Diener MK, Knaebel HP, Heukaufer C, Antes G, Büchler MW, Seiler CM
Ann Surg 2007 Feb;245(2):187-200. doi: 10.1097/01.sla.0000242711.74502.a9. PMID: 17245171Free PMC Article

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