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Bone Schwannoma

MedGen UID:
234024
•Concept ID:
C1332476
•
Neoplastic Process
Synonyms: Benign Bone Neurilemmoma; Benign Bone Schwannoma; Benign Neurilemmoma of Bone; Benign Neurilemmoma of the Bone; Benign Schwannoma of Bone; Benign Schwannoma of the Bone

Definition

A very rare schwannoma of the bone. It is often located in the mandible and is well circumscribed. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBone Schwannoma

Professional guidelines

PubMed

The many faces of solitary fibrous tumor; diversity of histological features, differential diagnosis and role of molecular studies and surrogate markers in avoiding misdiagnosis and predicting the behavior.
Tariq MU, Din NU, Abdul-Ghafar J, Park YK
Diagn Pathol 2021 Apr 20;16(1):32. doi: 10.1186/s13000-021-01095-2. PMID: 33879215Free PMC Article
Causes and management of facial nerve palsy.
Spencer CR, Irving RM
Br J Hosp Med (Lond) 2016 Dec 2;77(12):686-691. doi: 10.12968/hmed.2016.77.12.686. PMID: 27937022
Diagnosis, prevention and treatment of hereditary sensorineural hearing loss.
Proctor C
Laryngoscope 1977 Oct;87(10 Pt 2 Suppl 7):1-60. doi: 10.1288/00005537-197710001-00001. PMID: 408571

Recent clinical studies

Etiology

Middle Cranial Fossa Approach for Sporadic Vestibular Schwannoma: Patient Selection, Technical Pearls, and Hearing Results.
Kashani RG, Kocharyan A, Claussen AD, Gantz BJ, Hansen MR
Otolaryngol Clin North Am 2023 Jun;56(3):495-507. Epub 2023 Apr 3 doi: 10.1016/j.otc.2023.02.009. PMID: 37019769
Histopathologic Evaluation of Intralabyrinthine Schwannoma.
Bagattini M, Quesnel AM, Röösli C
Audiol Neurootol 2021;26(4):265-272. Epub 2020 Dec 22 doi: 10.1159/000511634. PMID: 33352553Free PMC Article
Translabyrinthine approach: indications, techniques, and results.
Arriaga MA, Lin J
Otolaryngol Clin North Am 2012 Apr;45(2):399-415, ix. Epub 2012 Feb 21 doi: 10.1016/j.otc.2011.12.009. PMID: 22483824
Retrosigmoid approach: indications, techniques, and results.
Elhammady MS, Telischi FF, Morcos JJ
Otolaryngol Clin North Am 2012 Apr;45(2):375-97, ix. doi: 10.1016/j.otc.2012.02.001. PMID: 22483823
Intramuscular neurilemoma.
Kwon BC, Baek GH, Chung MS, Lee SH, Kim HS, Oh JH
J Bone Joint Surg Br 2003 Jul;85(5):723-5. PMID: 12892197

Diagnosis

Hybrid Schwannoma-Perineurioma of the Orbit.
Zhou B, Milman T, Rodriguez FJ, Turbin RE, Langer PD
Ophthalmic Plast Reconstr Surg 2024 Jan-Feb 01;40(1):e1-e4. Epub 2023 Aug 8 doi: 10.1097/IOP.0000000000002484. PMID: 37552498
Spinal Schwannomas; Classification, Management And Outcomes.
Sohail A, Tariq A, Virani QU, Aziz HF, Shamim MS
J Pak Med Assoc 2023 Oct;73(10):2118-2120. doi: 10.47391/JPMA.23-75. PMID: 37876087
Large, Presacral Schwannoma: Imaging and Treatment.
Pfeiffer J, White CL
PM R 2021 Apr;13(4):427-428. Epub 2020 Oct 16 doi: 10.1002/pmrj.12492. PMID: 32945112
Nonparaganglioma jugular foramen tumors.
Thomas AJ, Wiggins RH 3rd, Gurgel RK
Otolaryngol Clin North Am 2015 Apr;48(2):343-59. Epub 2015 Feb 4 doi: 10.1016/j.otc.2014.12.008. PMID: 25659512
Olfactory groove schwannoma--case report.
Murakami M, Tsukahara T, Hatano T, Nakakuki T, Ogino E, Aoyama T
Neurol Med Chir (Tokyo) 2004 Apr;44(4):191-4. doi: 10.2176/nmc.44.191. PMID: 15185758

Therapy

Orbital Schwannoma With Frontal Bone Lysis.
Farag A, Farag S, Daigle P
J Craniofac Surg 2023 May 1;34(3):e298-e300. Epub 2023 Mar 16 doi: 10.1097/SCS.0000000000009246. PMID: 36922380
Translabyrinthine approach: indications, techniques, and results.
Arriaga MA, Lin J
Otolaryngol Clin North Am 2012 Apr;45(2):399-415, ix. Epub 2012 Feb 21 doi: 10.1016/j.otc.2011.12.009. PMID: 22483824
Retrosigmoid approach: indications, techniques, and results.
Elhammady MS, Telischi FF, Morcos JJ
Otolaryngol Clin North Am 2012 Apr;45(2):375-97, ix. doi: 10.1016/j.otc.2012.02.001. PMID: 22483823
Radiosurgery and radiotherapy for sacral tumors.
Gibbs IC, Chang SD
Neurosurg Focus 2003 Aug 15;15(2):E8. doi: 10.3171/foc.2003.15.2.8. PMID: 15350039
Radiation tolerance of normal temporal bone structures: implications for gamma knife stereotactic radiosurgery.
Linskey ME, Johnstone PA
Int J Radiat Oncol Biol Phys 2003 Sep 1;57(1):196-200. doi: 10.1016/s0360-3016(03)00413-9. PMID: 12909233

Prognosis

Causes and management of facial nerve palsy.
Spencer CR, Irving RM
Br J Hosp Med (Lond) 2016 Dec 2;77(12):686-691. doi: 10.12968/hmed.2016.77.12.686. PMID: 27937022
Nonparaganglioma jugular foramen tumors.
Thomas AJ, Wiggins RH 3rd, Gurgel RK
Otolaryngol Clin North Am 2015 Apr;48(2):343-59. Epub 2015 Feb 4 doi: 10.1016/j.otc.2014.12.008. PMID: 25659512
Translabyrinthine approach: indications, techniques, and results.
Arriaga MA, Lin J
Otolaryngol Clin North Am 2012 Apr;45(2):399-415, ix. Epub 2012 Feb 21 doi: 10.1016/j.otc.2011.12.009. PMID: 22483824
Extra-axial brain tumors.
Drevelegas A
Eur Radiol 2005 Mar;15(3):453-67. Epub 2004 Dec 31 doi: 10.1007/s00330-004-2557-0. PMID: 15627190
Radiation-induced schwannomas.
Rubinstein AB, Reichenthal E, Borohov H
Neurosurgery 1989 Jun;24(6):929-32. doi: 10.1227/00006123-198906000-00026. PMID: 2747873

Clinical prediction guides

Orbital Schwannoma With Frontal Bone Lysis.
Farag A, Farag S, Daigle P
J Craniofac Surg 2023 May 1;34(3):e298-e300. Epub 2023 Mar 16 doi: 10.1097/SCS.0000000000009246. PMID: 36922380
Histopathologic Evaluation of Intralabyrinthine Schwannoma.
Bagattini M, Quesnel AM, Röösli C
Audiol Neurootol 2021;26(4):265-272. Epub 2020 Dec 22 doi: 10.1159/000511634. PMID: 33352553Free PMC Article
Nonparaganglioma jugular foramen tumors.
Thomas AJ, Wiggins RH 3rd, Gurgel RK
Otolaryngol Clin North Am 2015 Apr;48(2):343-59. Epub 2015 Feb 4 doi: 10.1016/j.otc.2014.12.008. PMID: 25659512
Extra-axial brain tumors.
Drevelegas A
Eur Radiol 2005 Mar;15(3):453-67. Epub 2004 Dec 31 doi: 10.1007/s00330-004-2557-0. PMID: 15627190
Adult infratentorial tumors.
Bilaniuk LT
Semin Roentgenol 1990 Apr;25(2):155-73. doi: 10.1016/0037-198x(90)90047-8. PMID: 2349487

Recent systematic reviews

Is It Time for a Paradigm Shift in the Surgical Management of Trigeminal Schwannomas? Evaluating the Role of the Transorbital Approach: An Anatomo-Clinical Study and Systematic Literature Review.
Corrivetti F, de Notaris M, Seneca V, Di Nuzzo G, Catapano G
World Neurosurg 2024 Oct;190:e1025-e1037. Epub 2024 Aug 14 doi: 10.1016/j.wneu.2024.08.055. PMID: 39151698
Impact of Obesity on Postoperative Complications after Lateral Skull Base Surgery: A Systematic Review.
Bridgham K, Shikara M, Ludeman E, Eisenman DJ
ORL J Otorhinolaryngol Relat Spec 2023;85(5):264-274. Epub 2023 Aug 21 doi: 10.1159/000531531. PMID: 37604124
Comparison of translabyrinthine and retrosigmoid approach for treating vestibular schwannoma: A meta-analysis.
Jun W, Gao YL, Yu HG, Huang QL, Long XQ, Liu GH, Ting X, Zhong XY, Zhou YF
Clin Neurol Neurosurg 2020 Sep;196:105994. Epub 2020 Jun 6 doi: 10.1016/j.clineuro.2020.105994. PMID: 32540713
Surgical Management of Mandibular Intraosseous Schwannomas.
DeLeonibus A, Bassiri Gharb B, Papay F, Zins JE, Rampazzo A
J Craniofac Surg 2017 Jun;28(4):e307-e311. doi: 10.1097/SCS.0000000000003557. PMID: 28212127
Indications and contraindications of auditory brainstem implants: systematic review and illustrative cases.
Merkus P, Di Lella F, Di Trapani G, Pasanisi E, Beltrame MA, Zanetti D, Negri M, Sanna M
Eur Arch Otorhinolaryngol 2014 Jan;271(1):3-13. Epub 2013 Feb 13 doi: 10.1007/s00405-013-2378-3. PMID: 23404468

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