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Type C Lymphomatoid Papulosis

MedGen UID:
232430
•Concept ID:
C1333297
•
Neoplastic Process
Synonyms: Diffuse Large Cell Type Lymphomatoid Papulosis; Diffuse Large Cell Type LyP; Type C LyP

Definition

A variant of lymphomatoid papulosis characterized clinically by regressing skin papules, and morphologically by features resembling anaplastic large cell lymphoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVType C Lymphomatoid Papulosis

Professional guidelines

PubMed

Histopathological aspects and differential diagnosis of CD8 positive lymphomatoid papulosis.
Marschalkó M, Gyöngyösi N, Noll J, Károlyi Z, Wikonkál N, Hársing J, Kuroli E, Csomor J, Matolcsy A, Sarolta K, Szepesi Á
J Cutan Pathol 2016 Nov;43(11):963-973. Epub 2016 Aug 30 doi: 10.1111/cup.12779. PMID: 27461449
Lymphomatoid papulosis: Treatment response and associated lymphomas in a study of 180 patients.
Wieser I, Oh CW, Talpur R, Duvic M
J Am Acad Dermatol 2016 Jan;74(1):59-67. Epub 2015 Oct 28 doi: 10.1016/j.jaad.2015.09.013. PMID: 26518172
Contribution of longitudinal follow up and clinical pathological correlation in the diagnosis CD30-positive skin infiltrates.
De Souza A, Carter JB, Harris NL, Ferry JA, Duncan LM
J Cutan Pathol 2015 Jul;42(7):452-8. Epub 2015 Jun 4 doi: 10.1111/cup.12510. PMID: 25931140

Recent clinical studies

Diagnosis

Pediatric oral Epstein-Barr virus associated self-remitting CD30+ lymphoproliferative disorder: A distinct entity.
Schwartz Z, Bowe RB, Coleman M, Magro CM
Ann Diagn Pathol 2018 Dec;37:57-61. Epub 2018 Sep 12 doi: 10.1016/j.anndiagpath.2018.08.004. PMID: 30292067
Clonal T-cell receptor β-chain gene rearrangements in differential diagnosis of lymphomatoid papulosis from skin metastasis of nodal anaplastic large-cell lymphoma.
Akilov OE, Pillai RK, Grandinetti LM, Kant JA, Geskin L
Arch Dermatol 2011 Aug;147(8):943-7. doi: 10.1001/archdermatol.2011.187. PMID: 21844453Free PMC Article

Clinical prediction guides

Clonal T-cell receptor β-chain gene rearrangements in differential diagnosis of lymphomatoid papulosis from skin metastasis of nodal anaplastic large-cell lymphoma.
Akilov OE, Pillai RK, Grandinetti LM, Kant JA, Geskin L
Arch Dermatol 2011 Aug;147(8):943-7. doi: 10.1001/archdermatol.2011.187. PMID: 21844453Free PMC Article

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