U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Papilloma of buccal mucosa

MedGen UID:
231971
•Concept ID:
C1332641
•
Neoplastic Process
Synonyms: Buccal Mucosa Papilloma; buccal mucosa papilloma; Buccal Squamous Cell Papilloma; Buccal Squamous Papilloma; Papilloma of Buccal Mucosa; papilloma of buccal mucosa; Papilloma of the Buccal Mucosa; papilloma of the buccal mucosa
SNOMED CT: Papilloma of buccal mucosa (448147005)
 
Monarch Initiative: MONDO:0021276

Definition

A benign, exophytic and polypoid growth that arises from the buccal mucosa. It is covered by hyperplastic epithelium. Some cases are caused by human papillomavirus infection. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPapilloma of buccal mucosa

Professional guidelines

PubMed

HPV Lesions and Other Issues in the Oral Cavity Treatment and Removal without Pain.
El Moussaoui S, Mallandrich M, Garrós N, Calpena AC, Rodríguez Lagunas MJ, Fernández-Campos F
Int J Mol Sci 2021 Oct 16;22(20) doi: 10.3390/ijms222011158. PMID: 34681818Free PMC Article
Transmission of human papillomavirus DNA from patient to surgical masks, gloves and oral mucosa of medical personnel during treatment of laryngeal papillomas and genital warts.
Ilmarinen T, Auvinen E, Hiltunen-Back E, Ranki A, Aaltonen LM, Pitkäranta A
Eur Arch Otorhinolaryngol 2012 Nov;269(11):2367-71. Epub 2012 May 16 doi: 10.1007/s00405-012-2049-9. PMID: 22588197
Low prevalence of high risk genotypes of human papilloma virus in normal oral mucosa, oral leukoplakia and verrucous carcinoma.
Saghravanian N, Ghazvini K, Babakoohi S, Firooz A, Mohtasham N
Acta Odontol Scand 2011 Nov;69(6):406-9. Epub 2011 Apr 5 doi: 10.3109/00016357.2011.572560. PMID: 21466259

Recent clinical studies

Etiology

HPV-Related Papillary Lesions of the Oral Mucosa: A Review.
Betz SJ
Head Neck Pathol 2019 Mar;13(1):80-90. Epub 2019 Jan 29 doi: 10.1007/s12105-019-01003-7. PMID: 30693456Free PMC Article
Oral and vulvovaginal changes in pregnancy.
Ramos-E-Silva M, Martins NR, Kroumpouzos G
Clin Dermatol 2016 May-Jun;34(3):353-8. Epub 2016 Mar 2 doi: 10.1016/j.clindermatol.2016.02.007. PMID: 27265073
The role of human papillomavirus in oral disease.
Pringle GA
Dent Clin North Am 2014 Apr;58(2):385-99. doi: 10.1016/j.cden.2013.12.008. PMID: 24655529
Human papilloma virus--role in precancerous and cancerous oral lesions of tobacco chewers.
Zil-A-Rubab, Baig S, Siddiqui A, Nayeem A, Salman M, Qidwai MA, Mallick R, Qidwai S
J Pak Med Assoc 2013 Oct;63(10):1295-8. PMID: 24392564
Human papilloma virus and oral infections: an update.
Kumaraswamy KL, Vidhya M
J Cancer Res Ther 2011 Apr-Jun;7(2):120-7. doi: 10.4103/0973-1482.82915. PMID: 21768696

Diagnosis

HPV-Related Papillary Lesions of the Oral Mucosa: A Review.
Betz SJ
Head Neck Pathol 2019 Mar;13(1):80-90. Epub 2019 Jan 29 doi: 10.1007/s12105-019-01003-7. PMID: 30693456Free PMC Article
Multifocal Epithelial Hyperplasia.
Agnew C, Alexander S, Prabhu N
J Dent Child (Chic) 2017 Jan 15;84(1):47-49. PMID: 28387191
Human papillomavirus and Epstein-Barr virus associated conditions of the oral mucosa.
Stojanov IJ, Woo SB
Semin Diagn Pathol 2015 Jan;32(1):3-11. Epub 2014 Dec 19 doi: 10.1053/j.semdp.2014.12.003. PMID: 25749203
The role of human papillomavirus in oral disease.
Pringle GA
Dent Clin North Am 2014 Apr;58(2):385-99. doi: 10.1016/j.cden.2013.12.008. PMID: 24655529
Warty dyskeratoma.
Anneroth A, Isacsson G
Acta Derm Venereol 1975;55(3):227-32. PMID: 50698

Therapy

Role of Transoral Robotic Surgery in the Work-up of the Unknown Primary.
de Almeida JR
Otolaryngol Clin North Am 2020 Dec;53(6):965-980. Epub 2020 Sep 18 doi: 10.1016/j.otc.2020.07.008. PMID: 32951898
Oral HPV infection: current strategies for prevention and therapy.
Syrjanen S, Termine N, Capra G, Paderni C, Panzarella V, Campisi G
Curr Pharm Des 2012;18(34):5452-69. doi: 10.2174/138161212803307581. PMID: 22632393
Oral premalignant lesions: from a clinical perspective.
Amagasa T, Yamashiro M, Uzawa N
Int J Clin Oncol 2011 Feb;16(1):5-14. Epub 2011 Jan 12 doi: 10.1007/s10147-010-0157-3. PMID: 21225307
Oral cytology in cannabis smokers.
Darling MR, Learmonth GM, Arendorf TM
SADJ 2002 Apr;57(4):132-5. PMID: 12078330
Oral lesions.
Hinds EC, Kent JN
Am J Gastroenterol 1971 Mar;55(3):225-36. PMID: 4931041

Prognosis

Retrospective Study of Buccal Mucosal Salivary Neoplasms.
Alramadhan SA, Fitzpatrick SG, Cohen DM, Bhattacharyya I, Islam MN
Head Neck Pathol 2020 Dec;14(4):1013-1020. Epub 2020 Jun 6 doi: 10.1007/s12105-020-01190-8. PMID: 32506376Free PMC Article
Herpes simplex and human papilloma virus coinfections in oral mucosa of men-A 6-year follow-up study.
Mäki J, Paavilainen H, Kero K, Hukkanen V, Syrjänen S
J Med Virol 2018 Mar;90(3):564-570. Epub 2017 Oct 20 doi: 10.1002/jmv.24965. PMID: 28975630
Human papillomavirus and Epstein-Barr virus associated conditions of the oral mucosa.
Stojanov IJ, Woo SB
Semin Diagn Pathol 2015 Jan;32(1):3-11. Epub 2014 Dec 19 doi: 10.1053/j.semdp.2014.12.003. PMID: 25749203
Role of human papilloma virus in the oral carcinogenesis: an Indian perspective.
Chocolatewala NM, Chaturvedi P
J Cancer Res Ther 2009 Apr-Jun;5(2):71-7. doi: 10.4103/0973-1482.52788. PMID: 19542661
Ductal papillomas of salivary gland origin: A report of 19 cases and a review of the literature.
Brannon RB, Sciubba JJ, Giulani M
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2001 Jul;92(1):68-77. doi: 10.1067/moe.2001.115978. PMID: 11458248

Clinical prediction guides

Human papillomavirus and Epstein-Barr virus associated conditions of the oral mucosa.
Stojanov IJ, Woo SB
Semin Diagn Pathol 2015 Jan;32(1):3-11. Epub 2014 Dec 19 doi: 10.1053/j.semdp.2014.12.003. PMID: 25749203
Human papillomavirus infections of the oral mucosa and upper respiratory tract.
Nguyen HP, McNiece KL, Duong AA, Khan F
Curr Probl Dermatol 2014;45:132-53. Epub 2014 Mar 13 doi: 10.1159/000357904. PMID: 24643183
Role of beta-defensins in oral epithelial health and disease.
Abiko Y, Saitoh M, Nishimura M, Yamazaki M, Sawamura D, Kaku T
Med Mol Morphol 2007 Dec;40(4):179-84. Epub 2007 Dec 21 doi: 10.1007/s00795-007-0381-8. PMID: 18085375
Valuation of exfoliative cytology as prediction factor in oral mucosa lesions.
Brunotto M, Zárate AM, Cismondi A, Fernández Mdel C, Noher de Halac RI
Med Oral Patol Oral Cir Bucal 2005 Jul 1;10 Suppl 2:E92-102. PMID: 15995578
Multifocal papilloma virus epithelial hyperplasia.
Carlos R, Sedano HO
Oral Surg Oral Med Oral Pathol 1994 Jun;77(6):631-5. doi: 10.1016/0030-4220(94)90325-5. PMID: 8065729

Recent systematic reviews

Primary Tumour Detection in Carcinoma of Unknown Primary with Transoral Robotic Surgery (TORS) Tongue Base Mucosectomy: A Meta-analysis.
Gupta KK, Khan H, Mughal Z, De M, Sharma N, Garas G
Ann Surg Oncol 2024 Sep;31(9):6065-6076. Epub 2024 Jul 9 doi: 10.1245/s10434-024-15758-z. PMID: 38980583

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...