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Refractory Burkitt Lymphoma

MedGen UID:
208955
•Concept ID:
C0855105
•
Neoplastic Process
Synonyms: Burkitt's Lymphoma Refractory; Refractory Burkitt's Lymphoma

Definition

Burkitt lymphoma that is resistant to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory Burkitt Lymphoma

Professional guidelines

PubMed

Treatment of relapsed/refractory paediatric aggressive B-cell non-Hodgkin lymphoma.
Moleti ML, Testi AM, Foà R
Br J Haematol 2020 Jun;189(5):826-843. Epub 2020 Mar 6 doi: 10.1111/bjh.16461. PMID: 32141616
Introduction of novel agents in the treatment of primary CNS lymphoma.
Grommes C, Nayak L, Tun HW, Batchelor TT
Neuro Oncol 2019 Feb 19;21(3):306-313. doi: 10.1093/neuonc/noy193. PMID: 30423172Free PMC Article
Advances in the diagnosis and treatment of childhood and adolescent B-cell non-Hodgkin lymphoma.
El-Mallawany NK, Cairo MS
Clin Adv Hematol Oncol 2015 Feb;13(2):113-23. PMID: 25774481

Recent clinical studies

Etiology

Targeted therapy in Burkitt lymphoma: Small molecule inhibitors under investigation.
Atallah-Yunes SA, Habermann TM, Khurana A
Br J Haematol 2024 Jun;204(6):2165-2172. Epub 2024 Apr 5 doi: 10.1111/bjh.19425. PMID: 38577716
Bone Marrow Aplasia after CAR-T-Cell Therapy for Relapsed/Refractory Burkitt's Lymphoma.
Kenkel TJ, Sridhar N, Hammons LR, Hintzke M, Shah NN
Med Sci (Basel) 2023 Oct 12;11(4) doi: 10.3390/medsci11040067. PMID: 37873752Free PMC Article
Successful Treatment of Pediatric Refractory Burkitt Lymphoma PTLD after Liver Transplantation using Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy.
Wang T, Feng M, Luo C, Wan X, Pan C, Tang J, Xue F, Yin M, Lu D, Xia Q, Li B, Chen J
Cell Transplant 2021 Jan-Dec;30:963689721996649. doi: 10.1177/0963689721996649. PMID: 33631963Free PMC Article
Nebulized Vasopressin for the Control of Hematemesis and Hemoptysis in a Child With Recurrent, Refractory Stage III Burkitt Lymphoma.
Dulin JD, Coyne PJ
J Palliat Care 2020 Apr;35(2):71-74. Epub 2019 Nov 3 doi: 10.1177/0825859719883844. PMID: 31680640
High-dose therapy and autologous stem cell transplantation for children with HIV-associated non-Hodgkin lymphoma.
Fluri S, Ammann R, Lüthy AR, Hirt A, Aebi C, Duppenthaler A, Leibundgut K
Pediatr Blood Cancer 2007 Dec;49(7):984-7. doi: 10.1002/pbc.20900. PMID: 16685736

Diagnosis

Refractory Burkitt Lymphoma With False-positive and False-negative Mass Detected on Positron Emission Tomography-computed Tomography After Chemotherapy.
Shima H, Takaki T, Ito J, Iwabuchi Y, Nakazawa A, Shimada H
J Pediatr Hematol Oncol 2023 Oct 1;45(7):e915-e916. Epub 2023 Jul 6 doi: 10.1097/MPH.0000000000002709. PMID: 37526341
Successful Treatment of Pediatric Refractory Burkitt Lymphoma PTLD after Liver Transplantation using Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy.
Wang T, Feng M, Luo C, Wan X, Pan C, Tang J, Xue F, Yin M, Lu D, Xia Q, Li B, Chen J
Cell Transplant 2021 Jan-Dec;30:963689721996649. doi: 10.1177/0963689721996649. PMID: 33631963Free PMC Article
Two Cases of Neurolymphomatosis with Fatal Bilateral Vocal Cord Paralysis that were Diagnosed with (18)F-fluorodeoxyglucose Positron Emission Tomography (FDG PET)/CT.
Ono Y, Kazuma Y, Ochi Y, Matsuoka R, Imai Y, Ishikawa T
Intern Med 2017;56(10):1193-1198. Epub 2017 May 15 doi: 10.2169/internalmedicine.56.6998. PMID: 28502935Free PMC Article

Therapy

Targeted therapy in Burkitt lymphoma: Small molecule inhibitors under investigation.
Atallah-Yunes SA, Habermann TM, Khurana A
Br J Haematol 2024 Jun;204(6):2165-2172. Epub 2024 Apr 5 doi: 10.1111/bjh.19425. PMID: 38577716
Bone Marrow Aplasia after CAR-T-Cell Therapy for Relapsed/Refractory Burkitt's Lymphoma.
Kenkel TJ, Sridhar N, Hammons LR, Hintzke M, Shah NN
Med Sci (Basel) 2023 Oct 12;11(4) doi: 10.3390/medsci11040067. PMID: 37873752Free PMC Article
Successful Treatment of Pediatric Refractory Burkitt Lymphoma PTLD after Liver Transplantation using Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy.
Wang T, Feng M, Luo C, Wan X, Pan C, Tang J, Xue F, Yin M, Lu D, Xia Q, Li B, Chen J
Cell Transplant 2021 Jan-Dec;30:963689721996649. doi: 10.1177/0963689721996649. PMID: 33631963Free PMC Article
Nebulized Vasopressin for the Control of Hematemesis and Hemoptysis in a Child With Recurrent, Refractory Stage III Burkitt Lymphoma.
Dulin JD, Coyne PJ
J Palliat Care 2020 Apr;35(2):71-74. Epub 2019 Nov 3 doi: 10.1177/0825859719883844. PMID: 31680640
Relapsed/refractory Burkitt lymphoma and HIV infection.
Khan A, Brahim A, Ruiz M, Nagovski N
Int J STD AIDS 2018 Jun;29(7):695-703. Epub 2017 Dec 21 doi: 10.1177/0956462417748239. PMID: 29264956

Prognosis

Targeted therapy in Burkitt lymphoma: Small molecule inhibitors under investigation.
Atallah-Yunes SA, Habermann TM, Khurana A
Br J Haematol 2024 Jun;204(6):2165-2172. Epub 2024 Apr 5 doi: 10.1111/bjh.19425. PMID: 38577716
Bone Marrow Aplasia after CAR-T-Cell Therapy for Relapsed/Refractory Burkitt's Lymphoma.
Kenkel TJ, Sridhar N, Hammons LR, Hintzke M, Shah NN
Med Sci (Basel) 2023 Oct 12;11(4) doi: 10.3390/medsci11040067. PMID: 37873752Free PMC Article
Case Report: Unedited allogeneic chimeric antigen receptor T cell bridging to conditioning-free hematopoietic stem cell transplantation for a child with refractory Burkitt lymphoma.
Yang X, Luo C, Qian J, Huang X, Zhang J, Wang J, Luo C, Qin X, Li B, Chen J
Front Immunol 2023;14:1219872. Epub 2023 Sep 6 doi: 10.3389/fimmu.2023.1219872. PMID: 37736096Free PMC Article
Sequential anti-CD19, 22, and 20 autologous chimeric antigen receptor T-cell (CAR-T) treatments of a child with relapsed refractory Burkitt lymphoma: a case report and literature review.
Du J, Zhang Y
J Cancer Res Clin Oncol 2020 Jun;146(6):1575-1582. Epub 2020 Mar 28 doi: 10.1007/s00432-020-03198-7. PMID: 32222815
Nebulized Vasopressin for the Control of Hematemesis and Hemoptysis in a Child With Recurrent, Refractory Stage III Burkitt Lymphoma.
Dulin JD, Coyne PJ
J Palliat Care 2020 Apr;35(2):71-74. Epub 2019 Nov 3 doi: 10.1177/0825859719883844. PMID: 31680640

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