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Male orgasm disorder

MedGen UID:
19560
•Concept ID:
C0033949
•
Mental or Behavioral Dysfunction
Synonyms: Inhibited male orgasm; inhibited male orgasm; male orgasm disorder; Male orgasmic disorder; Male Orgasmic Disorder; male orgasmic disorder
SNOMED CT: Inhibited male orgasm (81903006); Male orgasmic disorder (81903006)
 
Monarch Initiative: MONDO:0003522

Definition

Persistent delay or absence in orgasm not accounted for by a medical reason. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMale orgasm disorder

Professional guidelines

PubMed

Diagnosis and Management of Priapism.
Fantus RJ, Brannigan RE, Davis AM
JAMA 2023 Aug 8;330(6):559-560. doi: 10.1001/jama.2023.13377. PMID: 37471069
Current diagnosis and management of erectile dysfunction.
McMahon CG
Med J Aust 2019 Jun;210(10):469-476. Epub 2019 May 17 doi: 10.5694/mja2.50167. PMID: 31099420
Endocrine Treatment of Gender-Dysphoric/Gender-Incongruent Persons: An Endocrine Society Clinical Practice Guideline.
Hembree WC, Cohen-Kettenis PT, Gooren L, Hannema SE, Meyer WJ, Murad MH, Rosenthal SM, Safer JD, Tangpricha V, T'Sjoen GG
J Clin Endocrinol Metab 2017 Nov 1;102(11):3869-3903. doi: 10.1210/jc.2017-01658. PMID: 28945902

Recent clinical studies

Etiology

Androgen therapy for women after menopause.
Marko KI, Simon JA
Best Pract Res Clin Endocrinol Metab 2021 Dec;35(6):101592. Epub 2021 Oct 12 doi: 10.1016/j.beem.2021.101592. PMID: 34674962
Risks of Testosterone for Postmenopausal Women.
Pinkerton JV, Blackman I, Conner EA, Kaunitz AM
Endocrinol Metab Clin North Am 2021 Mar;50(1):139-150. Epub 2021 Jan 11 doi: 10.1016/j.ecl.2020.10.007. PMID: 33518182
Delayed orgasm and anorgasmia.
Jenkins LC, Mulhall JP
Fertil Steril 2015 Nov;104(5):1082-8. Epub 2015 Oct 9 doi: 10.1016/j.fertnstert.2015.09.029. PMID: 26439762Free PMC Article
Introduction: Ejaculatory problems and male infertility.
Sigman M
Fertil Steril 2015 Nov;104(5):1049-50. Epub 2015 Oct 1 doi: 10.1016/j.fertnstert.2015.09.026. PMID: 26432529
Male sexual dysfunction.
Diaz VA Jr, Close JD
Prim Care 2010 Sep;37(3):473-89, vii-viii. Epub 2010 Jun 18 doi: 10.1016/j.pop.2010.04.002. PMID: 20705194

Diagnosis

Sexual Performance Anxiety.
Pyke RE
Sex Med Rev 2020 Apr;8(2):183-190. Epub 2019 Aug 22 doi: 10.1016/j.sxmr.2019.07.001. PMID: 31447414
INFERTILITY AND SEXUAL DYSFUNCTIONS: A SYSTEMATIC LITERATURE REVIEW.
Starc A, Trampuš M, Pavan Jukić D, Rotim C, Jukić T, Polona Mivšek A
Acta Clin Croat 2019 Sep;58(3):508-515. doi: 10.20471/acc.2019.58.03.15. PMID: 31969764Free PMC Article
Delayed orgasm and anorgasmia.
Jenkins LC, Mulhall JP
Fertil Steril 2015 Nov;104(5):1082-8. Epub 2015 Oct 9 doi: 10.1016/j.fertnstert.2015.09.029. PMID: 26439762Free PMC Article
A validated measure of no sexual attraction: the Asexuality Identification Scale.
Yule MA, Brotto LA, Gorzalka BB
Psychol Assess 2015 Mar;27(1):148-60. Epub 2014 Nov 10 doi: 10.1037/a0038196. PMID: 25383584
Sexual dysfunctions: classifications and definitions.
Hatzimouratidis K, Hatzichristou D
J Sex Med 2007 Jan;4(1):241-250. doi: 10.1111/j.1743-6109.2007.00409.x. PMID: 17233791

Therapy

Androgen therapy for women after menopause.
Marko KI, Simon JA
Best Pract Res Clin Endocrinol Metab 2021 Dec;35(6):101592. Epub 2021 Oct 12 doi: 10.1016/j.beem.2021.101592. PMID: 34674962
Risks of Testosterone for Postmenopausal Women.
Pinkerton JV, Blackman I, Conner EA, Kaunitz AM
Endocrinol Metab Clin North Am 2021 Mar;50(1):139-150. Epub 2021 Jan 11 doi: 10.1016/j.ecl.2020.10.007. PMID: 33518182
Sexual Performance Anxiety.
Pyke RE
Sex Med Rev 2020 Apr;8(2):183-190. Epub 2019 Aug 22 doi: 10.1016/j.sxmr.2019.07.001. PMID: 31447414
Depression and sexuality.
Reynaert C, Zdanowicz N, Janne P, Jacques D
Psychiatr Danub 2010 Nov;22 Suppl 1:S111-3. PMID: 21057415
Antidepressant-induced sexual dysfunction.
Segraves RT
J Clin Psychiatry 1998;59 Suppl 4:48-54. PMID: 9554321

Prognosis

Gender incongruence and gender dysphoria in childhood and adolescence-current insights in diagnostics, management, and follow-up.
Claahsen-van der Grinten H, Verhaak C, Steensma T, Middelberg T, Roeffen J, Klink D
Eur J Pediatr 2021 May;180(5):1349-1357. Epub 2020 Dec 18 doi: 10.1007/s00431-020-03906-y. PMID: 33337526Free PMC Article
Delayed orgasm and anorgasmia.
Jenkins LC, Mulhall JP
Fertil Steril 2015 Nov;104(5):1082-8. Epub 2015 Oct 9 doi: 10.1016/j.fertnstert.2015.09.029. PMID: 26439762Free PMC Article
Psychosocial aspects of ejaculatory dysfunction and male reproduction.
Wincze JP
Fertil Steril 2015 Nov;104(5):1089-94. Epub 2015 Aug 19 doi: 10.1016/j.fertnstert.2015.07.1155. PMID: 26297900
Depression and sexuality.
Reynaert C, Zdanowicz N, Janne P, Jacques D
Psychiatr Danub 2010 Nov;22 Suppl 1:S111-3. PMID: 21057415
Sexual dysfunction in the United States: prevalence and predictors.
Laumann EO, Paik A, Rosen RC
JAMA 1999 Feb 10;281(6):537-44. doi: 10.1001/jama.281.6.537. PMID: 10022110

Clinical prediction guides

Sexual Dysfunction in Schizophrenia: A Systematic Review and Meta-Analysis.
Korchia T, Achour V, Faugere M, Albeash A, Yon DK, Boyer L, Fond G
JAMA Psychiatry 2023 Nov 1;80(11):1110-1120. doi: 10.1001/jamapsychiatry.2023.2696. PMID: 37703012Free PMC Article
Evaluation of the efficacy and safety of Tribulus terrestris in male sexual dysfunction-A prospective, randomized, double-blind, placebo-controlled clinical trial.
Kamenov Z, Fileva S, Kalinov K, Jannini EA
Maturitas 2017 May;99:20-26. Epub 2017 Feb 12 doi: 10.1016/j.maturitas.2017.01.011. PMID: 28364864
Delayed orgasm and anorgasmia.
Jenkins LC, Mulhall JP
Fertil Steril 2015 Nov;104(5):1082-8. Epub 2015 Oct 9 doi: 10.1016/j.fertnstert.2015.09.029. PMID: 26439762Free PMC Article
Renal replacement and male sexuality.
Hegarty PK, Olsburgh J
Transplant Proc 2012 Jul-Aug;44(6):1804-5. doi: 10.1016/j.transproceed.2012.05.055. PMID: 22841278
A double-blind, randomized, pilot dose-finding study of maca root (L. meyenii) for the management of SSRI-induced sexual dysfunction.
Dording CM, Fisher L, Papakostas G, Farabaugh A, Sonawalla S, Fava M, Mischoulon D
CNS Neurosci Ther 2008 Fall;14(3):182-91. doi: 10.1111/j.1755-5949.2008.00052.x. PMID: 18801111Free PMC Article

Recent systematic reviews

Transidentities and autism spectrum disorder: A systematic review.
Bouzy J, Brunelle J, Cohen D, Condat A
Psychiatry Res 2023 May;323:115176. Epub 2023 Mar 28 doi: 10.1016/j.psychres.2023.115176. PMID: 36996732
European Association of Urology Guidelines on Sexual and Reproductive Health-2021 Update: Male Sexual Dysfunction.
Salonia A, Bettocchi C, Boeri L, Capogrosso P, Carvalho J, Cilesiz NC, Cocci A, Corona G, Dimitropoulos K, Gül M, Hatzichristodoulou G, Jones TH, Kadioglu A, Martínez Salamanca JI, Milenkovic U, Modgil V, Russo GI, Serefoglu EC, Tharakan T, Verze P, Minhas S; EAU Working Group on Male Sexual and Reproductive Health
Eur Urol 2021 Sep;80(3):333-357. Epub 2021 Jun 26 doi: 10.1016/j.eururo.2021.06.007. PMID: 34183196
INFERTILITY AND SEXUAL DYSFUNCTIONS: A SYSTEMATIC LITERATURE REVIEW.
Starc A, Trampuš M, Pavan Jukić D, Rotim C, Jukić T, Polona Mivšek A
Acta Clin Croat 2019 Sep;58(3):508-515. doi: 10.20471/acc.2019.58.03.15. PMID: 31969764Free PMC Article
Prostate cancer screening with prostate-specific antigen (PSA) test: a systematic review and meta-analysis.
Ilic D, Djulbegovic M, Jung JH, Hwang EC, Zhou Q, Cleves A, Agoritsas T, Dahm P
BMJ 2018 Sep 5;362:k3519. doi: 10.1136/bmj.k3519. PMID: 30185521Free PMC Article
Erectile Dysfunction: AUA Guideline.
Burnett AL, Nehra A, Breau RH, Culkin DJ, Faraday MM, Hakim LS, Heidelbaugh J, Khera M, McVary KT, Miner MM, Nelson CJ, Sadeghi-Nejad H, Seftel AD, Shindel AW
J Urol 2018 Sep;200(3):633-641. Epub 2018 May 7 doi: 10.1016/j.juro.2018.05.004. PMID: 29746858

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