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Abnormal change in social behavior

MedGen UID:
1853244
•Concept ID:
C5872981
•
Finding
HPO: HP:5200243

Definition

An alternation in the habits and emotional tendencies of an individual with a change in behavior that is typically noticed by family members or peers. [from HPO]

Professional guidelines

PubMed

Isradipine therapy in Cacna1dIle772Met/+ mice ameliorates primary aldosteronism and neurologic abnormalities.
Stölting G, Dinh HA, Volkert M, Hellmig N, Schewe J, Hennicke L, Seidel E, Oberacher H, Zhang J, Lifton RP, Urban I, Long M, Rivalan M, Nottoli T, Scholl UI
JCI Insight 2023 Oct 23;8(20) doi: 10.1172/jci.insight.162468. PMID: 37698934Free PMC Article
Eating Disorders in Primary Care: Diagnosis and Management.
Klein DA, Sylvester JE, Schvey NA
Am Fam Physician 2021 Jan 1;103(1):22-32. PMID: 33382560
Marfan syndrome-diagnosis and management.
Ammash NM, Sundt TM, Connolly HM
Curr Probl Cardiol 2008 Jan;33(1):7-39. doi: 10.1016/j.cpcardiol.2007.10.001. PMID: 18155514

Recent clinical studies

Etiology

Enhancing social behavior in an autism spectrum disorder mouse model: investigating the underlying mechanisms of Lactiplantibacillus plantarum intervention.
Chen CM, Wu CC, Kim Y, Hsu WY, Tsai YC, Chiu SL
Gut Microbes 2024 Jan-Dec;16(1):2359501. Epub 2024 Jun 6 doi: 10.1080/19490976.2024.2359501. PMID: 38841895Free PMC Article
Adolescent stress impairs postpartum social behavior via anterior insula-prelimbic pathway in mice.
Kin K, Francis-Oliveira J, Kano SI, Niwa M
Nat Commun 2023 May 23;14(1):2975. doi: 10.1038/s41467-023-38799-6. PMID: 37221211Free PMC Article
Does race or ethnicity play a role in the origin, pathophysiology, and outcomes of preeclampsia? An expert review of the literature.
Johnson JD, Louis JM
Am J Obstet Gynecol 2022 Feb;226(2S):S876-S885. Epub 2020 Jul 24 doi: 10.1016/j.ajog.2020.07.038. PMID: 32717255
The Evidence for Saturated Fat and for Sugar Related to Coronary Heart Disease.
DiNicolantonio JJ, Lucan SC, O'Keefe JH
Prog Cardiovasc Dis 2016 Mar-Apr;58(5):464-72. Epub 2015 Nov 14 doi: 10.1016/j.pcad.2015.11.006. PMID: 26586275Free PMC Article
Psychological issues in patient outcomes.
Sarwer DB, Crerand CE
Facial Plast Surg 2002 May;18(2):125-33. doi: 10.1055/s-2002-32203. PMID: 12063660

Diagnosis

Eating Disorders in Primary Care: Diagnosis and Management.
Klein DA, Sylvester JE, Schvey NA
Am Fam Physician 2021 Jan 1;103(1):22-32. PMID: 33382560
Microbiota Transfer Therapy alters gut ecosystem and improves gastrointestinal and autism symptoms: an open-label study.
Kang DW, Adams JB, Gregory AC, Borody T, Chittick L, Fasano A, Khoruts A, Geis E, Maldonado J, McDonough-Means S, Pollard EL, Roux S, Sadowsky MJ, Lipson KS, Sullivan MB, Caporaso JG, Krajmalnik-Brown R
Microbiome 2017 Jan 23;5(1):10. doi: 10.1186/s40168-016-0225-7. PMID: 28122648Free PMC Article
The Evidence for Saturated Fat and for Sugar Related to Coronary Heart Disease.
DiNicolantonio JJ, Lucan SC, O'Keefe JH
Prog Cardiovasc Dis 2016 Mar-Apr;58(5):464-72. Epub 2015 Nov 14 doi: 10.1016/j.pcad.2015.11.006. PMID: 26586275Free PMC Article
Metabolic features of the cell danger response.
Naviaux RK
Mitochondrion 2014 May;16:7-17. Epub 2013 Aug 24 doi: 10.1016/j.mito.2013.08.006. PMID: 23981537
Frontotemporal dementia.
Perry DC, Miller BL
Semin Neurol 2013 Sep;33(4):336-41. Epub 2013 Nov 14 doi: 10.1055/s-0033-1359316. PMID: 24234354

Therapy

Enhancing social behavior in an autism spectrum disorder mouse model: investigating the underlying mechanisms of Lactiplantibacillus plantarum intervention.
Chen CM, Wu CC, Kim Y, Hsu WY, Tsai YC, Chiu SL
Gut Microbes 2024 Jan-Dec;16(1):2359501. Epub 2024 Jun 6 doi: 10.1080/19490976.2024.2359501. PMID: 38841895Free PMC Article
Microbiota Transfer Therapy alters gut ecosystem and improves gastrointestinal and autism symptoms: an open-label study.
Kang DW, Adams JB, Gregory AC, Borody T, Chittick L, Fasano A, Khoruts A, Geis E, Maldonado J, McDonough-Means S, Pollard EL, Roux S, Sadowsky MJ, Lipson KS, Sullivan MB, Caporaso JG, Krajmalnik-Brown R
Microbiome 2017 Jan 23;5(1):10. doi: 10.1186/s40168-016-0225-7. PMID: 28122648Free PMC Article
The Evidence for Saturated Fat and for Sugar Related to Coronary Heart Disease.
DiNicolantonio JJ, Lucan SC, O'Keefe JH
Prog Cardiovasc Dis 2016 Mar-Apr;58(5):464-72. Epub 2015 Nov 14 doi: 10.1016/j.pcad.2015.11.006. PMID: 26586275Free PMC Article
Sulforaphane treatment of autism spectrum disorder (ASD).
Singh K, Connors SL, Macklin EA, Smith KD, Fahey JW, Talalay P, Zimmerman AW
Proc Natl Acad Sci U S A 2014 Oct 28;111(43):15550-5. Epub 2014 Oct 13 doi: 10.1073/pnas.1416940111. PMID: 25313065Free PMC Article
Cardio-oncology/onco-cardiology.
Hong RA, Iimura T, Sumida KN, Eager RM
Clin Cardiol 2010 Dec;33(12):733-7. doi: 10.1002/clc.20823. PMID: 21184556Free PMC Article

Prognosis

Developmental associations between cognition and adaptive behavior in intellectual and developmental disability.
Dakopolos A, Condy E, Smith E, Harvey D, Kaat AJ, Coleman J, Riley K, Berry-Kravis E, Hessl D
J Neurodev Disord 2024 Jun 13;16(1):31. doi: 10.1186/s11689-024-09542-z. PMID: 38872099Free PMC Article
Genetic landscape of congenital insensitivity to pain and hereditary sensory and autonomic neuropathies.
Lischka A, Eggermann K, Record CJ, Dohrn MF, Laššuthová P, Kraft F, Begemann M, Dey D, Eggermann T, Beijer D, Šoukalová J, Laura M, Rossor AM, Mazanec R, Van Lent J, Tomaselli PJ, Ungelenk M, Debus KY, Feely SME, Gläser D, Jagadeesh S, Martin M, Govindaraj GM, Singhi P, Baineni R, Biswal N, Ibarra-Ramírez M, Bonduelle M, Gess B, Romero Sánchez J, Suthar R, Udani V, Nalini A, Unnikrishnan G, Marques W Junior, Mercier S, Procaccio V, Bris C, Suresh B, Reddy V, Skorupinska M, Bonello-Palot N, Mochel F, Dahl G, Sasidharan K, Devassikutty FM, Nampoothiri S, Rodovalho Doriqui MJ, Müller-Felber W, Vill K, Haack TB, Dufke A, Abele M, Stucka R, Siddiqi S, Ullah N, Spranger S, Chiabrando D, Bolgül BS, Parman Y, Seeman P, Lampert A, Schulz JB, Wood JN, Cox JJ, Auer-Grumbach M, Timmerman V, de Winter J, Themistocleous AC, Shy M, Bennett DL, Baets J, Hübner CA, Leipold E, Züchner S, Elbracht M, Çakar A, Senderek J, Hornemann T, Woods CG, Reilly MM, Kurth I
Brain 2023 Dec 1;146(12):4880-4890. doi: 10.1093/brain/awad328. PMID: 37769650Free PMC Article
The Evidence for Saturated Fat and for Sugar Related to Coronary Heart Disease.
DiNicolantonio JJ, Lucan SC, O'Keefe JH
Prog Cardiovasc Dis 2016 Mar-Apr;58(5):464-72. Epub 2015 Nov 14 doi: 10.1016/j.pcad.2015.11.006. PMID: 26586275Free PMC Article
Cardio-oncology/onco-cardiology.
Hong RA, Iimura T, Sumida KN, Eager RM
Clin Cardiol 2010 Dec;33(12):733-7. doi: 10.1002/clc.20823. PMID: 21184556Free PMC Article
Frontotemporal dementia.
Honig LS, Bell K, Chin SS
Sci Aging Knowledge Environ 2003 Apr 2;2003(13):DN1. doi: 10.1126/sageke.2003.13.dn1. PMID: 12844524

Clinical prediction guides

Exposure to different surface-modified polystyrene nanoparticles caused anxiety, depression, and social deficit in mice via damaging mitochondria in neurons.
Ma Y, Xu D, Wan Z, Wei Z, Chen Z, Wang Y, Han X, Chen Y
Sci Total Environ 2024 Apr 1;919:170739. Epub 2024 Feb 9 doi: 10.1016/j.scitotenv.2024.170739. PMID: 38340854
Genetic landscape of congenital insensitivity to pain and hereditary sensory and autonomic neuropathies.
Lischka A, Eggermann K, Record CJ, Dohrn MF, Laššuthová P, Kraft F, Begemann M, Dey D, Eggermann T, Beijer D, Šoukalová J, Laura M, Rossor AM, Mazanec R, Van Lent J, Tomaselli PJ, Ungelenk M, Debus KY, Feely SME, Gläser D, Jagadeesh S, Martin M, Govindaraj GM, Singhi P, Baineni R, Biswal N, Ibarra-Ramírez M, Bonduelle M, Gess B, Romero Sánchez J, Suthar R, Udani V, Nalini A, Unnikrishnan G, Marques W Junior, Mercier S, Procaccio V, Bris C, Suresh B, Reddy V, Skorupinska M, Bonello-Palot N, Mochel F, Dahl G, Sasidharan K, Devassikutty FM, Nampoothiri S, Rodovalho Doriqui MJ, Müller-Felber W, Vill K, Haack TB, Dufke A, Abele M, Stucka R, Siddiqi S, Ullah N, Spranger S, Chiabrando D, Bolgül BS, Parman Y, Seeman P, Lampert A, Schulz JB, Wood JN, Cox JJ, Auer-Grumbach M, Timmerman V, de Winter J, Themistocleous AC, Shy M, Bennett DL, Baets J, Hübner CA, Leipold E, Züchner S, Elbracht M, Çakar A, Senderek J, Hornemann T, Woods CG, Reilly MM, Kurth I
Brain 2023 Dec 1;146(12):4880-4890. doi: 10.1093/brain/awad328. PMID: 37769650Free PMC Article
The Evidence for Saturated Fat and for Sugar Related to Coronary Heart Disease.
DiNicolantonio JJ, Lucan SC, O'Keefe JH
Prog Cardiovasc Dis 2016 Mar-Apr;58(5):464-72. Epub 2015 Nov 14 doi: 10.1016/j.pcad.2015.11.006. PMID: 26586275Free PMC Article
Sulforaphane treatment of autism spectrum disorder (ASD).
Singh K, Connors SL, Macklin EA, Smith KD, Fahey JW, Talalay P, Zimmerman AW
Proc Natl Acad Sci U S A 2014 Oct 28;111(43):15550-5. Epub 2014 Oct 13 doi: 10.1073/pnas.1416940111. PMID: 25313065Free PMC Article
Cardio-oncology/onco-cardiology.
Hong RA, Iimura T, Sumida KN, Eager RM
Clin Cardiol 2010 Dec;33(12):733-7. doi: 10.1002/clc.20823. PMID: 21184556Free PMC Article

Recent systematic reviews

Social isolation and the brain: effects and mechanisms.
Xiong Y, Hong H, Liu C, Zhang YQ
Mol Psychiatry 2023 Jan;28(1):191-201. Epub 2022 Nov 25 doi: 10.1038/s41380-022-01835-w. PMID: 36434053Free PMC Article
Behavior Problems and Social Competence in Fragile X Syndrome: A Systematic Review.
Cregenzán-Royo O, Brun-Gasca C, Fornieles-Deu A
Genes (Basel) 2022 Jan 30;13(2) doi: 10.3390/genes13020280. PMID: 35205326Free PMC Article
Information needs in people with diabetes mellitus: a systematic review.
Biernatzki L, Kuske S, Genz J, Ritschel M, Stephan A, Bächle C, Droste S, Grobosch S, Ernstmann N, Chernyak N, Icks A
Syst Rev 2018 Feb 14;7(1):27. doi: 10.1186/s13643-018-0690-0. PMID: 29444711Free PMC Article
Interventions for psychotic symptoms concomitant with epilepsy.
Farooq S, Sherin A
Cochrane Database Syst Rev 2015 Dec 21;2015(12):CD006118. doi: 10.1002/14651858.CD006118.pub3. PMID: 26690687Free PMC Article
Neurobiological changes after intervention in individuals with anti-social behaviour: a literature review.
Cornet LJ, de Kogel CH, Nijman HL, Raine A, van der Laan PH
Crim Behav Ment Health 2015 Feb;25(1):10-27. Epub 2014 Jun 3 doi: 10.1002/cbm.1915. PMID: 24888269

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