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Abnormal perceptual state

MedGen UID:: 1853226
•Concept ID:: C5872973
•: Mental or Behavioral Dysfunction

HPO:	HP:5200216

Definition

Temporary alteration of the awareness of reality or self-perception. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVAbnormal perceptual state

Congenital Systemic Disorder
- Abnormality of the nervous system
  - Abnormal nervous system physiology
    - Abnormality of mental function
      - Abnormal experience of reality
        Abnormal interpretation of external stimuli
        Abnormal perceptual state
        Autoscopy
        Depersonalization
        Derealization
        Dissociation

Professional guidelines

PubMed

Clinical safety of daridorexant in insomnia treatment: Analysis of FDA adverse event reports.

Wang Q, Zhou Q, Du Z, Lu R, Jiang Y, Zhu H
J Affect Disord 2024 Oct 1;362:552-559. Epub 2024 Jul 15 doi: 10.1016/j.jad.2024.07.034. PMID: 39019232

Diagnosis and Management of Velopharyngeal Dysfunction.

Glade RS, Deal R
Oral Maxillofac Surg Clin North Am 2016 May;28(2):181-8. doi: 10.1016/j.coms.2015.12.004. PMID: 27150305

Assessment and management of breathlessness.

Altose MD
Chest 1985 Aug;88(2 Suppl):77S-83S. doi: 10.1378/chest.88.2_supplement.77s. PMID: 3926399

See all (19)

Recent clinical studies

Etiology

Clinical safety of daridorexant in insomnia treatment: Analysis of FDA adverse event reports.

Wang Q, Zhou Q, Du Z, Lu R, Jiang Y, Zhu H
J Affect Disord 2024 Oct 1;362:552-559. Epub 2024 Jul 15 doi: 10.1016/j.jad.2024.07.034. PMID: 39019232

Effect of vestibular rehabilitation games in patients with persistent postural perceptual dizziness and its relation to anxiety and depression: prospective study.

Ibrahim NMK, Hazza NMA, Yaseen DM, Galal EM
Eur Arch Otorhinolaryngol 2024 Jun;281(6):2861-2869. Epub 2023 Dec 21 doi: 10.1007/s00405-023-08369-z. PMID: 38127098 Free PMC Article

Brain Insulin Signaling is Associated with Late-Life Cognitive Decline.

Tong H, Capuano AW, Carmichael OT, Gwizdala KL, Bennett DA, Ahima RS, Arnold SE, Arvanitakis Z
Aging Dis 2024 Oct 1;15(5):2205-2215. doi: 10.14336/AD.2023.1117. PMID: 38029396 Free PMC Article

Large-scale brain functional network abnormalities in social anxiety disorder.

Zhang X, Yang X, Wu B, Pan N, He M, Wang S, Kemp GJ, Gong Q
Psychol Med 2023 Oct;53(13):6194-6204. Epub 2022 Nov 4 doi: 10.1017/S0033291722003439. PMID: 36330833 Free PMC Article

Ataxic dysarthria.

Kent RD, Kent JF, Duffy JR, Thomas JE, Weismer G, Stuntebeck S
J Speech Lang Hear Res 2000 Oct;43(5):1275-89. doi: 10.1044/jslhr.4305.1275. PMID: 11063247

See all (452)

Diagnosis

Perceptual Consequences of Cochlear Deafferentation in Humans.

Bramhall NF, McMillan GP
Trends Hear 2024 Jan-Dec;28:23312165241239541. doi: 10.1177/23312165241239541. PMID: 38738337 Free PMC Article

Amblyopia.

Levi DM
Handb Clin Neurol 2021;178:13-30. doi: 10.1016/B978-0-12-821377-3.00002-7. PMID: 33832673

Epidemiology of Erosive Tooth Wear, Dental Fluorosis and Molar Incisor Hypomineralization in the American Continent.

Martignon S, Bartlett D, Manton DJ, Martinez-Mier EA, Splieth C, Avila V
Caries Res 2021;55(1):1-11. Epub 2021 Jan 13 doi: 10.1159/000512483. PMID: 33440378

Assessment of Mental Status.

Finney GR, Minagar A, Heilman KM
Neurol Clin 2016 Feb;34(1):1-16. doi: 10.1016/j.ncl.2015.08.001. PMID: 26613992

Psychosis as a state of aberrant salience: a framework linking biology, phenomenology, and pharmacology in schizophrenia.

Kapur S
Am J Psychiatry 2003 Jan;160(1):13-23. doi: 10.1176/appi.ajp.160.1.13. PMID: 12505794

See all (412)

Therapy

Clinical safety of daridorexant in insomnia treatment: Analysis of FDA adverse event reports.

Wang Q, Zhou Q, Du Z, Lu R, Jiang Y, Zhu H
J Affect Disord 2024 Oct 1;362:552-559. Epub 2024 Jul 15 doi: 10.1016/j.jad.2024.07.034. PMID: 39019232

Perceptual Consequences of Cochlear Deafferentation in Humans.

Bramhall NF, McMillan GP
Trends Hear 2024 Jan-Dec;28:23312165241239541. doi: 10.1177/23312165241239541. PMID: 38738337 Free PMC Article

Cochlear synaptopathy in acquired sensorineural hearing loss: Manifestations and mechanisms.

Liberman MC, Kujawa SG
Hear Res 2017 Jun;349:138-147. Epub 2017 Jan 10 doi: 10.1016/j.heares.2017.01.003. PMID: 28087419 Free PMC Article

Psychosis as a state of aberrant salience: a framework linking biology, phenomenology, and pharmacology in schizophrenia.

Kapur S
Am J Psychiatry 2003 Jan;160(1):13-23. doi: 10.1176/appi.ajp.160.1.13. PMID: 12505794

Assessment and management of breathlessness.

Altose MD
Chest 1985 Aug;88(2 Suppl):77S-83S. doi: 10.1378/chest.88.2_supplement.77s. PMID: 3926399

See all (108)

Prognosis

Perceptual Consequences of Cochlear Deafferentation in Humans.

Bramhall NF, McMillan GP
Trends Hear 2024 Jan-Dec;28:23312165241239541. doi: 10.1177/23312165241239541. PMID: 38738337 Free PMC Article

Inability to move one's face dampens facial expression perception.

Japee S, Jordan J, Licht J, Lokey S; Moebius Syndrome Research Consortium, Chen G, Snow J, Jabs EW, Webb BD, Engle EC, Manoli I, Baker C, Ungerleider LG
Cortex 2023 Dec;169:35-49. Epub 2023 Sep 30 doi: 10.1016/j.cortex.2023.08.014. PMID: 37852041 Free PMC Article

An Active Inference Approach to Interoceptive Psychopathology.

Paulus MP, Feinstein JS, Khalsa SS
Annu Rev Clin Psychol 2019 May 7;15:97-122. doi: 10.1146/annurev-clinpsy-050718-095617. PMID: 31067416 Free PMC Article

The neural processes underlying perceptual decision making in humans: recent progress and future directions.

Kelly SP, O'Connell RG
J Physiol Paris 2015 Feb-Jun;109(1-3):27-37. Epub 2014 Sep 7 doi: 10.1016/j.jphysparis.2014.08.003. PMID: 25204272

Psychosis as a state of aberrant salience: a framework linking biology, phenomenology, and pharmacology in schizophrenia.

Kapur S
Am J Psychiatry 2003 Jan;160(1):13-23. doi: 10.1176/appi.ajp.160.1.13. PMID: 12505794

See all (181)

Clinical prediction guides

Abnormal large-scale brain functional network dynamics in social anxiety disorder.

Zhang X, Wu B, Yang X, Kemp GJ, Wang S, Gong Q
CNS Neurosci Ther 2024 Aug;30(8):e14904. doi: 10.1111/cns.14904. PMID: 39107947 Free PMC Article

Perceptual Consequences of Cochlear Deafferentation in Humans.

Bramhall NF, McMillan GP
Trends Hear 2024 Jan-Dec;28:23312165241239541. doi: 10.1177/23312165241239541. PMID: 38738337 Free PMC Article

Pons-to-Cerebellum Hypoconnectivity Along the Psychosis Spectrum and Associations With Sensory Prediction and Hallucinations in Schizophrenia.

Abram SV, Hua JPY, Nicholas S, Roach B, Keedy S, Sweeney JA, Mathalon DH, Ford JM
Biol Psychiatry Cogn Neurosci Neuroimaging 2024 Jul;9(7):693-702. Epub 2024 Feb 2 doi: 10.1016/j.bpsc.2024.01.010. PMID: 38311290 Free PMC Article

Assessment of Mental Status.

Finney GR, Minagar A, Heilman KM
Neurol Clin 2016 Feb;34(1):1-16. doi: 10.1016/j.ncl.2015.08.001. PMID: 26613992

Psychosis as a state of aberrant salience: a framework linking biology, phenomenology, and pharmacology in schizophrenia.

Kapur S
Am J Psychiatry 2003 Jan;160(1):13-23. doi: 10.1176/appi.ajp.160.1.13. PMID: 12505794

See all (362)

Recent systematic reviews

The Association between Fat-Free Mass and Exercise Test Outcomes in People with Chronic Obstructive Pulmonary Disease: A Systematic Review.

Gaynor-Sodeifi K, Lewthwaite H, Jenkins AR, Fernandes Belo L, Koch E, Mujaddid A, Raffoul D, Tracey L, Jensen D
COPD 2022;19(1):182-205. doi: 10.1080/15412555.2022.2049737. PMID: 35410561

Neuroimaging studies in persistent postural-perceptual dizziness and related disease: a systematic review.

Cao Z, Liu X, Ju Y, Zhao X
J Neurol 2022 Mar;269(3):1225-1235. Epub 2021 May 21 doi: 10.1007/s00415-021-10558-x. PMID: 34019178

Sensory evoked potentials in patients with Rett syndrome through the lens of animal studies: Systematic review.

Sysoeva OV, Smirnov K, Stroganova TA
Clin Neurophysiol 2020 Jan;131(1):213-224. Epub 2019 Nov 21 doi: 10.1016/j.clinph.2019.11.003. PMID: 31812082

Case Report of a Primary Pituitary Abscess and Systematic Literature Review of Pituitary Abscess with a Focus on Patient Outcomes.

Agyei JO, Lipinski LJ, Leonardo J
World Neurosurg 2017 May;101:76-92. Epub 2017 Jan 31 doi: 10.1016/j.wneu.2017.01.077. PMID: 28153622

Tone-matching ability in patients with schizophrenia: A systematic review and meta-analysis.

Dondé C, Luck D, Grot S, Leitman DI, Brunelin J, Haesebaert F
Schizophr Res 2017 Mar;181:94-99. Epub 2016 Oct 11 doi: 10.1016/j.schres.2016.10.009. PMID: 27742161

See all (5)

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Abnormal perceptual state

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Clinical resources

Practice guidelines

Consumer resources

Reviews

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