U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Hypnagogic sleep paralysis

MedGen UID:
1853209
•Concept ID:
C5873010
•
Mental or Behavioral Dysfunction
Synonyms: Inability to move while falling asleep; Predormital sleep paralysis
 
HPO: HP:5200352

Definition

Sleep paralysis that occurs when falling asleep. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHypnagogic sleep paralysis

Professional guidelines

PubMed

Evaluating pitolisant as a narcolepsy treatment option.
de Biase S, Pellitteri G, Gigli GL, Valente M
Expert Opin Pharmacother 2021 Feb;22(2):155-162. Epub 2020 Sep 17 doi: 10.1080/14656566.2020.1817387. PMID: 32941089
Investigational therapies for the treatment of narcolepsy.
de Biase S, Nilo A, Gigli GL, Valente M
Expert Opin Investig Drugs 2017 Aug;26(8):953-963. Epub 2017 Jul 20 doi: 10.1080/13543784.2017.1356819. PMID: 28726523
Management of narcolepsy.
Bhat A, El Solh AA
Expert Opin Pharmacother 2008 Jul;9(10):1721-33. doi: 10.1517/14656566.9.10.1721. PMID: 18570605

Recent clinical studies

Etiology

REM sleep in narcolepsy.
Thorpy MJ, Siegel JM, Dauvilliers Y
Sleep Med Rev 2024 Oct;77:101976. Epub 2024 Aug 3 doi: 10.1016/j.smrv.2024.101976. PMID: 39186901
Autonomic disturbances in narcolepsy.
Plazzi G, Moghadam KK, Maggi LS, Donadio V, Vetrugno R, Liguori R, Zoccoli G, Poli F, Pizza F, Pagotto U, Ferri R
Sleep Med Rev 2011 Jun;15(3):187-96. Epub 2010 Jul 14 doi: 10.1016/j.smrv.2010.05.002. PMID: 20634114
Narcolepsy in adolescents.
Sullivan SS
Adolesc Med State Art Rev 2010 Dec;21(3):542-55, x-xi. PMID: 21302860
Narcolepsy: clinical decision making for the primary care physician.
Khan F, Hazin R, Iqbal M
South Med J 2009 Dec;102(12):1246-52. doi: 10.1097/SMJ.0b013e3181bc6e39. PMID: 20016433
The treatment of sleep disorders.
Smeyatsky N, Baldwin D, Botros W, Gura R, Kurian T, Lambert MT, Patel AG, Steinert J, Priest RG
S Afr Med J 1992 May 2;Suppl:1-8. PMID: 1585214

Diagnosis

REM sleep, REM parasomnias, REM sleep behaviour disorder.
Szûcs A, Mutti C, Papp A, Halász P, Parrino L
Ideggyogy Sz 2022 May 30;75(5-06):171-182. doi: 10.18071/isz.75.0171. PMID: 35819343
Narcolepsy in adolescents.
Sullivan SS
Adolesc Med State Art Rev 2010 Dec;21(3):542-55, x-xi. PMID: 21302860
Neuroimaging of narcolepsy.
Dang-Vu TT, Desseilles M, Schwartz S, Maquet P
CNS Neurol Disord Drug Targets 2009 Aug;8(4):254-63. doi: 10.2174/187152709788921708. PMID: 19689307
Narcolepsy.
Mitler MM, Hajdukovic R, Erman M, Koziol JA
J Clin Neurophysiol 1990 Jan;7(1):93-118. doi: 10.1097/00004691-199001000-00008. PMID: 1968069Free PMC Article
Narcolepsy.
Murray TJ, Foley A
Can Med Assoc J 1974 Jan 5;110(1):63-6. PMID: 4809449Free PMC Article

Therapy

Narcolepsy in adolescents.
Sullivan SS
Adolesc Med State Art Rev 2010 Dec;21(3):542-55, x-xi. PMID: 21302860
Neuroimaging of narcolepsy.
Dang-Vu TT, Desseilles M, Schwartz S, Maquet P
CNS Neurol Disord Drug Targets 2009 Aug;8(4):254-63. doi: 10.2174/187152709788921708. PMID: 19689307
Management of narcolepsy.
Bhat A, El Solh AA
Expert Opin Pharmacother 2008 Jul;9(10):1721-33. doi: 10.1517/14656566.9.10.1721. PMID: 18570605
Narcolepsy.
Mitler MM, Hajdukovic R, Erman M, Koziol JA
J Clin Neurophysiol 1990 Jan;7(1):93-118. doi: 10.1097/00004691-199001000-00008. PMID: 1968069Free PMC Article
Narcolepsy.
Murray TJ, Foley A
Can Med Assoc J 1974 Jan 5;110(1):63-6. PMID: 4809449Free PMC Article

Prognosis

Pitolisant for treating patients with narcolepsy.
Li S, Yang J
Expert Rev Clin Pharmacol 2020 Feb;13(2):79-84. Epub 2020 Jan 23 doi: 10.1080/17512433.2020.1714435. PMID: 31937172
Investigational therapies for the treatment of narcolepsy.
de Biase S, Nilo A, Gigli GL, Valente M
Expert Opin Investig Drugs 2017 Aug;26(8):953-963. Epub 2017 Jul 20 doi: 10.1080/13543784.2017.1356819. PMID: 28726523
The diagnosis and treatment of pediatric narcolepsy.
Nevsimalova S
Curr Neurol Neurosci Rep 2014 Aug;14(8):469. doi: 10.1007/s11910-014-0469-1. PMID: 24954623
Narcolepsy in the pediatric population.
Viorritto EN, Kureshi SA, Owens JA
Curr Neurol Neurosci Rep 2012 Apr;12(2):175-81. doi: 10.1007/s11910-011-0246-3. PMID: 22213222
Narcolepsy.
Murray TJ, Foley A
Can Med Assoc J 1974 Jan 5;110(1):63-6. PMID: 4809449Free PMC Article

Clinical prediction guides

Increased creative thinking in narcolepsy.
Lacaux C, Izabelle C, Santantonio G, De Villèle L, Frain J, Lubart T, Pizza F, Plazzi G, Arnulf I, Oudiette D
Brain 2019 Jul 1;142(7):1988-1999. doi: 10.1093/brain/awz137. PMID: 31143939
Sodium Oxybate Treatment in Pediatric Type 1 Narcolepsy.
Moresco M, Pizza F, Antelmi E, Plazzi G
Curr Drug Metab 2018;19(13):1073-1079. doi: 10.2174/1389200219666180305153134. PMID: 29512449
Patient-Reported Measures of Narcolepsy: The Need for Better Assessment.
Kallweit U, Schmidt M, Bassetti CL
J Clin Sleep Med 2017 May 15;13(5):737-744. doi: 10.5664/jcsm.6596. PMID: 28162143Free PMC Article
The diagnosis and treatment of pediatric narcolepsy.
Nevsimalova S
Curr Neurol Neurosci Rep 2014 Aug;14(8):469. doi: 10.1007/s11910-014-0469-1. PMID: 24954623
Familial narcolepsy.
Stepień A, Staszewski J, Domzał TM, Rzeski M, Skrobowska E, Warczyńska A
Neurol Neurochir Pol 2007 Mar-Apr;41(2):134-40. PMID: 17530575

Recent systematic reviews

Evaluating pitolisant as a narcolepsy treatment option.
de Biase S, Pellitteri G, Gigli GL, Valente M
Expert Opin Pharmacother 2021 Feb;22(2):155-162. Epub 2020 Sep 17 doi: 10.1080/14656566.2020.1817387. PMID: 32941089
Pitolisant for treating patients with narcolepsy.
Li S, Yang J
Expert Rev Clin Pharmacol 2020 Feb;13(2):79-84. Epub 2020 Jan 23 doi: 10.1080/17512433.2020.1714435. PMID: 31937172
Health-Related Quality of Life in Patients With Narcolepsy: A Review of the Literature.
Raggi A, Plazzi G, Ferri R
J Nerv Ment Dis 2019 Feb;207(2):84-99. doi: 10.1097/NMD.0000000000000918. PMID: 30672873
Anesthetic Management of Narcolepsy Patients During Surgery: A Systematic Review.
Hu S, Singh M, Wong J, Auckley D, Hershner S, Kakkar R, Thorpy MJ, Chung F
Anesth Analg 2018 Jan;126(1):233-246. doi: 10.1213/ANE.0000000000002228. PMID: 29257771
Narcolepsy and effectiveness of gamma-hydroxybutyrate (GHB): a systematic review and meta-analysis of randomized controlled trials.
Boscolo-Berto R, Viel G, Montagnese S, Raduazzo DI, Ferrara SD, Dauvilliers Y
Sleep Med Rev 2012 Oct;16(5):431-43. Epub 2011 Nov 4 doi: 10.1016/j.smrv.2011.09.001. PMID: 22055895

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...