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Hypnopompic sleep paralysis

MedGen UID:
1853203
•Concept ID:
C3267175
•
Disease or Syndrome
Synonyms: Inability to move while awakening; Postdormital paralysis; Postdormital sleep paralysis
 
HPO: HP:5200353

Definition

Sleep paralysis that occurs when waking up from sleep. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHypnopompic sleep paralysis

Professional guidelines

PubMed

Treatment Options for Narcolepsy.
Barateau L, Lopez R, Dauvilliers Y
CNS Drugs 2016 May;30(5):369-79. doi: 10.1007/s40263-016-0337-4. PMID: 27155860
Narcolepsy in children: a diagnostic and management approach.
Babiker MO, Prasad M
Pediatr Neurol 2015 Jun;52(6):557-65. Epub 2015 Mar 2 doi: 10.1016/j.pediatrneurol.2015.02.020. PMID: 25838042
Treatment of narcolepsy.
Didato G, Nobili L
Expert Rev Neurother 2009 Jun;9(6):897-910. doi: 10.1586/ern.09.29. PMID: 19496692

Recent clinical studies

Etiology

REM sleep in narcolepsy.
Thorpy MJ, Siegel JM, Dauvilliers Y
Sleep Med Rev 2024 Oct;77:101976. Epub 2024 Aug 3 doi: 10.1016/j.smrv.2024.101976. PMID: 39186901
Excessive daytime sleepiness in cancer patients.
Jaumally BA, Das A, Cassell NC, Pachecho GN, Majid R, Bashoura L, Balachandran DD, Faiz SA
Sleep Breath 2021 Jun;25(2):1063-1067. Epub 2020 Sep 16 doi: 10.1007/s11325-020-02151-9. PMID: 32939599
The influence of narcolepsy on olfactory function: a review.
de Martin Truzzi G, Naufel MF, Tufik S, Coelho FM
Sleep Med 2020 Aug;72:75-81. Epub 2020 Mar 31 doi: 10.1016/j.sleep.2020.03.023. PMID: 32554327
Narcolepsy: clinical decision making for the primary care physician.
Khan F, Hazin R, Iqbal M
South Med J 2009 Dec;102(12):1246-52. doi: 10.1097/SMJ.0b013e3181bc6e39. PMID: 20016433
Depression: relationships to sleep paralysis and other sleep disturbances in a community sample.
Szklo-Coxe M, Young T, Finn L, Mignot E
J Sleep Res 2007 Sep;16(3):297-312. doi: 10.1111/j.1365-2869.2007.00600.x. PMID: 17716279Free PMC Article

Diagnosis

REM sleep in narcolepsy.
Thorpy MJ, Siegel JM, Dauvilliers Y
Sleep Med Rev 2024 Oct;77:101976. Epub 2024 Aug 3 doi: 10.1016/j.smrv.2024.101976. PMID: 39186901
The influence of narcolepsy on olfactory function: a review.
de Martin Truzzi G, Naufel MF, Tufik S, Coelho FM
Sleep Med 2020 Aug;72:75-81. Epub 2020 Mar 31 doi: 10.1016/j.sleep.2020.03.023. PMID: 32554327
Neuroimaging of narcolepsy.
Dang-Vu TT, Desseilles M, Schwartz S, Maquet P
CNS Neurol Disord Drug Targets 2009 Aug;8(4):254-63. doi: 10.2174/187152709788921708. PMID: 19689307
Treatment of narcolepsy.
Didato G, Nobili L
Expert Rev Neurother 2009 Jun;9(6):897-910. doi: 10.1586/ern.09.29. PMID: 19496692
Relations among hypnagogic and hypnopompic experiences associated with sleep paralysis.
Cheyne JA, Newby-Clark IR, Rueffer SD
J Sleep Res 1999 Dec;8(4):313-7. doi: 10.1046/j.1365-2869.1999.00165.x. PMID: 10646172

Therapy

The neuropharmacology of sleep paralysis hallucinations: serotonin 2A activation and a novel therapeutic drug.
Jalal B
Psychopharmacology (Berl) 2018 Nov;235(11):3083-3091. Epub 2018 Oct 5 doi: 10.1007/s00213-018-5042-1. PMID: 30288594Free PMC Article
Investigational therapies for the treatment of narcolepsy.
de Biase S, Nilo A, Gigli GL, Valente M
Expert Opin Investig Drugs 2017 Aug;26(8):953-963. Epub 2017 Jul 20 doi: 10.1080/13543784.2017.1356819. PMID: 28726523
Treatment Options for Narcolepsy.
Barateau L, Lopez R, Dauvilliers Y
CNS Drugs 2016 May;30(5):369-79. doi: 10.1007/s40263-016-0337-4. PMID: 27155860
Neuroimaging of narcolepsy.
Dang-Vu TT, Desseilles M, Schwartz S, Maquet P
CNS Neurol Disord Drug Targets 2009 Aug;8(4):254-63. doi: 10.2174/187152709788921708. PMID: 19689307
Treatment of narcolepsy.
Didato G, Nobili L
Expert Rev Neurother 2009 Jun;9(6):897-910. doi: 10.1586/ern.09.29. PMID: 19496692

Prognosis

Prevalence, incidence, evolution and associated factors of sleep paralysis in a longitudinal study of the US general population.
Ohayon MM, Pakpour AH
Sleep Med 2022 Oct;98:62-67. Epub 2022 Jun 11 doi: 10.1016/j.sleep.2022.06.003. PMID: 35785587
Investigational therapies for the treatment of narcolepsy.
de Biase S, Nilo A, Gigli GL, Valente M
Expert Opin Investig Drugs 2017 Aug;26(8):953-963. Epub 2017 Jul 20 doi: 10.1080/13543784.2017.1356819. PMID: 28726523
Sleep paralysis and "the bedroom intruder": the role of the right superior parietal, phantom pain and body image projection.
Jalal B, Ramachandran VS
Med Hypotheses 2014 Dec;83(6):755-7. Epub 2014 Oct 13 doi: 10.1016/j.mehy.2014.10.002. PMID: 25459150
Narcolepsy in the pediatric population.
Viorritto EN, Kureshi SA, Owens JA
Curr Neurol Neurosci Rep 2012 Apr;12(2):175-81. doi: 10.1007/s11910-011-0246-3. PMID: 22213222
Narcolepsy and idiopathic hypersomnolence.
Choo KL, Guilleminault C
Clin Chest Med 1998 Mar;19(1):169-81. doi: 10.1016/s0272-5231(05)70440-8. PMID: 9554226

Clinical prediction guides

Lemborexant, an orexin receptor antagonist sedative-hypnotic: Is it useful for insomnia in psychiatric disorders?
Keks NA, Hope J
Australas Psychiatry 2022 Aug;30(4):530-532. Epub 2022 May 1 doi: 10.1177/10398562221092310. PMID: 35491942
Excessive daytime sleepiness in cancer patients.
Jaumally BA, Das A, Cassell NC, Pachecho GN, Majid R, Bashoura L, Balachandran DD, Faiz SA
Sleep Breath 2021 Jun;25(2):1063-1067. Epub 2020 Sep 16 doi: 10.1007/s11325-020-02151-9. PMID: 32939599
Anesthetic Management of Narcolepsy Patients During Surgery: A Systematic Review.
Hu S, Singh M, Wong J, Auckley D, Hershner S, Kakkar R, Thorpy MJ, Chung F
Anesth Analg 2018 Jan;126(1):233-246. doi: 10.1213/ANE.0000000000002228. PMID: 29257771
Patient-Reported Measures of Narcolepsy: The Need for Better Assessment.
Kallweit U, Schmidt M, Bassetti CL
J Clin Sleep Med 2017 May 15;13(5):737-744. doi: 10.5664/jcsm.6596. PMID: 28162143Free PMC Article
Familial narcolepsy.
Stepień A, Staszewski J, Domzał TM, Rzeski M, Skrobowska E, Warczyńska A
Neurol Neurochir Pol 2007 Mar-Apr;41(2):134-40. PMID: 17530575

Recent systematic reviews

Evaluating pitolisant as a narcolepsy treatment option.
de Biase S, Pellitteri G, Gigli GL, Valente M
Expert Opin Pharmacother 2021 Feb;22(2):155-162. Epub 2020 Sep 17 doi: 10.1080/14656566.2020.1817387. PMID: 32941089
Anesthetic Management of Narcolepsy Patients During Surgery: A Systematic Review.
Hu S, Singh M, Wong J, Auckley D, Hershner S, Kakkar R, Thorpy MJ, Chung F
Anesth Analg 2018 Jan;126(1):233-246. doi: 10.1213/ANE.0000000000002228. PMID: 29257771

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