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Tactile hypersensitivity

MedGen UID:
1841901
•Concept ID:
C5826962
•
Finding
HPO: HP:5200061

Definition

A decreased tolerance to physical touch. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTactile hypersensitivity

Professional guidelines

PubMed

Successful management of dentin hypersensitivity: A narrative review.
Ramli R, Ghani N, Taib H, Mat-Baharin NH
Dent Med Probl 2022 Jul-Sep;59(3):451-460. doi: 10.17219/dmp/143354. PMID: 36206495
Treatment of dentin hypersensitivity.
Trushkowsky RD, Oquendo A
Dent Clin North Am 2011 Jul;55(3):599-608, x. doi: 10.1016/j.cden.2011.02.013. PMID: 21726693
Central sensitization: implications for the diagnosis and treatment of pain.
Woolf CJ
Pain 2011 Mar;152(3 Suppl):S2-S15. Epub 2010 Oct 18 doi: 10.1016/j.pain.2010.09.030. PMID: 20961685Free PMC Article

Recent clinical studies

Etiology

Clinical overlap between functional neurological disorders and autism spectrum disorders: a preliminary study.
Nisticò V, Goeta D, Iacono A, Tedesco R, Giordano B, Faggioli R, Priori A, Gambini O, Demartini B
Neurol Sci 2022 Aug;43(8):5067-5073. Epub 2022 May 5 doi: 10.1007/s10072-022-06048-1. PMID: 35511383Free PMC Article
Different forms of traumatic brain injuries cause different tactile hypersensitivity profiles.
Wattiez AS, Castonguay WC, Gaul OJ, Waite JS, Schmidt CM, Reis AS, Rea BJ, Sowers LP, Cintrón-Pérez CJ, Vázquez-Rosa E, Pieper AA, Russo AF
Pain 2021 Apr 1;162(4):1163-1175. doi: 10.1097/j.pain.0000000000002103. PMID: 33027220Free PMC Article
Clinical Efficacy of Different Dentin Desensitizers.
Eyüboğlu GB, Naiboğlu P
Oper Dent 2020 Nov 1;45(6):E317-E333. doi: 10.2341/19-258-C. PMID: 32516395
Tactile hypersensitivity and GABA concentration in the sensorimotor cortex of adults with autism.
Sapey-Triomphe LA, Lamberton F, Sonié S, Mattout J, Schmitz C
Autism Res 2019 Apr;12(4):562-575. Epub 2019 Jan 11 doi: 10.1002/aur.2073. PMID: 30632707
Use of a toothpaste containing 8% arginine and calcium carbonate for immediate and lasting relief of dentin hypersensitivity: A simple and effective in-office procedure.
Ayad F, Ayad N, Vazquez J, Zhang YP, Mateo LR, Cummins D
Am J Dent 2018 Jun;31(3):135-140. PMID: 30028931

Diagnosis

Clinical overlap between functional neurological disorders and autism spectrum disorders: a preliminary study.
Nisticò V, Goeta D, Iacono A, Tedesco R, Giordano B, Faggioli R, Priori A, Gambini O, Demartini B
Neurol Sci 2022 Aug;43(8):5067-5073. Epub 2022 May 5 doi: 10.1007/s10072-022-06048-1. PMID: 35511383Free PMC Article
Sharpened self-other distinction in attention deficit hyperactivity disorder.
Boehme R, Frost Karlsson M, Heilig M, Olausson H, Capusan AJ
Neuroimage Clin 2020;27:102317. Epub 2020 Jun 16 doi: 10.1016/j.nicl.2020.102317. PMID: 32599550Free PMC Article
Clinical Efficacy of Different Dentin Desensitizers.
Eyüboğlu GB, Naiboğlu P
Oper Dent 2020 Nov 1;45(6):E317-E333. doi: 10.2341/19-258-C. PMID: 32516395
Tactile hypersensitivity and GABA concentration in the sensorimotor cortex of adults with autism.
Sapey-Triomphe LA, Lamberton F, Sonié S, Mattout J, Schmitz C
Autism Res 2019 Apr;12(4):562-575. Epub 2019 Jan 11 doi: 10.1002/aur.2073. PMID: 30632707
Deletion of 14.7 Mb 2q32.3q33.3 with a marfanoid phenotype and hypothyroidism.
Tomaszewska A, Podbiol-Palenta A, Boter M, Geisler G, Wawrzkiewicz-Witkowska A, Galjaard RJ, Zajączek S, Srebniak MI
Am J Med Genet A 2013 Sep;161A(9):2347-51. Epub 2013 Aug 5 doi: 10.1002/ajmg.a.36076. PMID: 23918240

Therapy

Clinical Efficacy of Different Dentin Desensitizers.
Eyüboğlu GB, Naiboğlu P
Oper Dent 2020 Nov 1;45(6):E317-E333. doi: 10.2341/19-258-C. PMID: 32516395
Use of a toothpaste containing 8% arginine and calcium carbonate for immediate and lasting relief of dentin hypersensitivity: A simple and effective in-office procedure.
Ayad F, Ayad N, Vazquez J, Zhang YP, Mateo LR, Cummins D
Am J Dent 2018 Jun;31(3):135-140. PMID: 30028931
Nerve regenerative effects of GABA-B ligands in a model of neuropathic pain.
Magnaghi V, Castelnovo LF, Faroni A, Cavalli E, Caffino L, Colciago A, Procacci P, Pajardi G
Biomed Res Int 2014;2014:368678. Epub 2014 Jul 15 doi: 10.1155/2014/368678. PMID: 25165701Free PMC Article
Experimental evaluation of the analgesic effect of ibuprofen on primary and secondary hyperalgesia.
Petersen KL, Brennum J, Dahl JB
Pain 1997 Apr;70(2-3):167-74. doi: 10.1016/s0304-3959(96)03316-7. PMID: 9150290
The effectiveness of sodium fluoride iontophoresis in patients with sensitive teeth.
McBride MA, Gilpatrick RO, Fowler WL
Quintessence Int 1991 Aug;22(8):637-40. PMID: 1882058

Prognosis

Clinical Efficacy of Different Dentin Desensitizers.
Eyüboğlu GB, Naiboğlu P
Oper Dent 2020 Nov 1;45(6):E317-E333. doi: 10.2341/19-258-C. PMID: 32516395
Tactile hypersensitivity and GABA concentration in the sensorimotor cortex of adults with autism.
Sapey-Triomphe LA, Lamberton F, Sonié S, Mattout J, Schmitz C
Autism Res 2019 Apr;12(4):562-575. Epub 2019 Jan 11 doi: 10.1002/aur.2073. PMID: 30632707
Use of a toothpaste containing 8% arginine and calcium carbonate for immediate and lasting relief of dentin hypersensitivity: A simple and effective in-office procedure.
Ayad F, Ayad N, Vazquez J, Zhang YP, Mateo LR, Cummins D
Am J Dent 2018 Jun;31(3):135-140. PMID: 30028931
Comparing the efficacy in providing instant relief of dentin hypersensitivity of a new toothpaste containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride relative to a benchmark desensitizing toothpaste containing 2% potassium ion and 1450 ppm fluoride, and to a control toothpaste with 1450 ppm fluoride: a three-day clinical study in New Jersey, USA.
Nathoo S, Delgado E, Zhang YP, DeVizio W, Cummins D, Mateo LR
J Clin Dent 2009;20(4):123-30. PMID: 19831165
Comparing the efficacy in providing instant relief of dentin hypersensitivity of a new toothpaste containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride to a benchmark desensitizing toothpaste containing 2% potassium ion and 1450 ppm fluoride, and to a control toothpaste with 1450 ppm fluoride: a three-day clinical study in Mississauga, Canada.
Ayad F, Ayad N, Delgado E, Zhang YP, DeVizio W, Cummins D, Mateo LR
J Clin Dent 2009;20(4):115-22. PMID: 19831164

Clinical prediction guides

Tmem160 contributes to the establishment of discrete nerve injury-induced pain behaviors in male mice.
Segelcke D, Fischer HK, Hütte M, Dennerlein S, Benseler F, Brose N, Pogatzki-Zahn EM, Schmidt M
Cell Rep 2021 Dec 21;37(12):110152. doi: 10.1016/j.celrep.2021.110152. PMID: 34936870
Clinical Efficacy of Different Dentin Desensitizers.
Eyüboğlu GB, Naiboğlu P
Oper Dent 2020 Nov 1;45(6):E317-E333. doi: 10.2341/19-258-C. PMID: 32516395
Tactile hypersensitivity and GABA concentration in the sensorimotor cortex of adults with autism.
Sapey-Triomphe LA, Lamberton F, Sonié S, Mattout J, Schmitz C
Autism Res 2019 Apr;12(4):562-575. Epub 2019 Jan 11 doi: 10.1002/aur.2073. PMID: 30632707
Curcumin slows osteoarthritis progression and relieves osteoarthritis-associated pain symptoms in a post-traumatic osteoarthritis mouse model.
Zhang Z, Leong DJ, Xu L, He Z, Wang A, Navati M, Kim SJ, Hirsh DM, Hardin JA, Cobelli NJ, Friedman JM, Sun HB
Arthritis Res Ther 2016 Jun 3;18(1):128. doi: 10.1186/s13075-016-1025-y. PMID: 27260322Free PMC Article
TNF(alpha) modulation of visceral and spinal sensory processing.
Hermann GE, Holmes GM, Rogers RC
Curr Pharm Des 2005;11(11):1391-409. doi: 10.2174/1381612053507828. PMID: 15853670

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