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Osteoid osteoma

MedGen UID:
18221
•Concept ID:
C0029441
•
Neoplastic Process
Synonyms: Osteoid Osteoma; Osteoid Osteomas; Osteoma, Osteoid; Osteomas, Osteoid
SNOMED CT: Osteoid osteoma (71666005); Osteoid osteoma (302859004)
 
HPO: HP:0030433
Monarch Initiative: MONDO:0009808
OMIM®: 259550

Definition

A bening tumor of bone composed of a central zone named nidus which is an atypical bone completely enclosed within a well vascularized stroma and a peripheral sclerotic reaction zone. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOsteoid osteoma

Professional guidelines

PubMed

Osteoid osteoma: which is the best mininvasive treatment option?
Parmeggiani A, Martella C, Ceccarelli L, Miceli M, Spinnato P, Facchini G
Eur J Orthop Surg Traumatol 2021 Dec;31(8):1611-1624. Epub 2021 Apr 11 doi: 10.1007/s00590-021-02946-w. PMID: 33839926Free PMC Article
Spinal Tumor Ablation: Indications, Techniques, and Clinical Management.
Cazzato RL, Auloge P, De Marini P, Boatta E, Koch G, Dalili D, Rao PP, Garnon J, Gangi A
Tech Vasc Interv Radiol 2020 Jun;23(2):100677. Epub 2020 May 27 doi: 10.1016/j.tvir.2020.100677. PMID: 32591193
Stress fractures of the foot and ankle, part 2: site-specific etiology, imaging, and treatment, and differential diagnosis.
Mandell JC, Khurana B, Smith SE
Skeletal Radiol 2017 Sep;46(9):1165-1186. Epub 2017 Mar 25 doi: 10.1007/s00256-017-2632-7. PMID: 28343329

Recent clinical studies

Etiology

Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Odontogenic and Maxillofacial Bone Tumours.
Vered M, Wright JM
Head Neck Pathol 2022 Mar;16(1):63-75. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01404-7. PMID: 35312978Free PMC Article
What's new in bone forming tumours of the skeleton?
Franceschini N, Lam SW, Cleton-Jansen AM, Bovée JVMG
Virchows Arch 2020 Jan;476(1):147-157. Epub 2019 Nov 18 doi: 10.1007/s00428-019-02683-w. PMID: 31741049Free PMC Article
Stress fractures of the foot and ankle, part 2: site-specific etiology, imaging, and treatment, and differential diagnosis.
Mandell JC, Khurana B, Smith SE
Skeletal Radiol 2017 Sep;46(9):1165-1186. Epub 2017 Mar 25 doi: 10.1007/s00256-017-2632-7. PMID: 28343329
Radiofrequency treatment.
Rosenthal DI
Orthop Clin North Am 2006 Jul;37(3):475-84, viii. doi: 10.1016/j.ocl.2006.05.004. PMID: 16846772
Osteoid osteoma--osteoblastoma.
De Souza Diaz L, Frost HM
Cancer 1974 Apr;33(4):1075-81. doi: 10.1002/1097-0142(197404)33:4<1075::aid-cncr2820330427>3.0.co;2-4. PMID: 4819213

Diagnosis

Osteoid osteoma of the foot and ankle--A systematic review.
Jordan RW, Koç T, Chapman AW, Taylor HP
Foot Ankle Surg 2015 Dec;21(4):228-34. Epub 2015 May 8 doi: 10.1016/j.fas.2015.04.005. PMID: 26564722
Osteoid osteoma.
Boscainos PJ, Cousins GR, Kulshreshtha R, Oliver TB, Papagelopoulos PJ
Orthopedics 2013 Oct 1;36(10):792-800. doi: 10.3928/01477447-20130920-10. PMID: 24093694
Osteoid osteoma and osteoblastoma.
Atesok KI, Alman BA, Schemitsch EH, Peyser A, Mankin H
J Am Acad Orthop Surg 2011 Nov;19(11):678-89. doi: 10.5435/00124635-201111000-00004. PMID: 22052644
Osteoid osteoma.
Kitsoulis P, Mantellos G, Vlychou M
Acta Orthop Belg 2006 Apr;72(2):119-25. PMID: 16768252
Osteoid osteoma.
Kransdorf MJ, Stull MA, Gilkey FW, Moser RP Jr
Radiographics 1991 Jul;11(4):671-96. doi: 10.1148/radiographics.11.4.1887121. PMID: 1887121

Therapy

Spinal Tumor Ablation: Indications, Techniques, and Clinical Management.
Cazzato RL, Auloge P, De Marini P, Boatta E, Koch G, Dalili D, Rao PP, Garnon J, Gangi A
Tech Vasc Interv Radiol 2020 Jun;23(2):100677. Epub 2020 May 27 doi: 10.1016/j.tvir.2020.100677. PMID: 32591193
Microwave ablation of osteoid osteoma: initial experience and efficacy.
Rinzler ES, Shivaram GM, Shaw DW, Monroe EJ, Koo KSH
Pediatr Radiol 2019 Apr;49(4):566-570. Epub 2019 Jan 7 doi: 10.1007/s00247-018-4327-1. PMID: 30617514
Osteoid Osteoma.
Pfaff J, April MD
J Emerg Med 2016 May;50(5):780-1. Epub 2016 Feb 15 doi: 10.1016/j.jemermed.2016.01.005. PMID: 26899511
Atypical osteoid osteomas.
Ciftdemir M, Tuncel SA, Usta U
Eur J Orthop Surg Traumatol 2015 Jan;25(1):17-27. Epub 2013 Aug 23 doi: 10.1007/s00590-013-1291-1. PMID: 23975583
Osteoid osteoma and osteoblastoma.
Atesok KI, Alman BA, Schemitsch EH, Peyser A, Mankin H
J Am Acad Orthop Surg 2011 Nov;19(11):678-89. doi: 10.5435/00124635-201111000-00004. PMID: 22052644

Prognosis

Benign tumors of the spine.
Thakur NA, Daniels AH, Schiller J, Valdes MA, Czerwein JK, Schiller A, Esmende S, Terek RM
J Am Acad Orthop Surg 2012 Nov;20(11):715-24. doi: 10.5435/JAAOS-20-11-715. PMID: 23118137
Osteoid osteoma and osteoblastoma.
Atesok KI, Alman BA, Schemitsch EH, Peyser A, Mankin H
J Am Acad Orthop Surg 2011 Nov;19(11):678-89. doi: 10.5435/00124635-201111000-00004. PMID: 22052644
Osteoid osteoma.
Kitsoulis P, Mantellos G, Vlychou M
Acta Orthop Belg 2006 Apr;72(2):119-25. PMID: 16768252
Osteoid-producing tumors of bone.
White LM, Kandel R
Semin Musculoskelet Radiol 2000;4(1):25-43. doi: 10.1055/s-2000-6853. PMID: 11061690
Osteoid osteoma--osteoblastoma.
De Souza Diaz L, Frost HM
Cancer 1974 Apr;33(4):1075-81. doi: 10.1002/1097-0142(197404)33:4<1075::aid-cncr2820330427>3.0.co;2-4. PMID: 4819213

Clinical prediction guides

New kids on the block: FOS and FOSB gene.
Cordier F, Creytens D
J Clin Pathol 2023 Nov;76(11):721-726. Epub 2023 Aug 8 doi: 10.1136/jcp-2023-208931. PMID: 37553246
Osteoid osteoma in the ankle and foot. An overview of 50 years of experience.
Payo-Ollero J, Moreno-Figaredo V, Llombart-Blanco R, Alfonso M, San Julián M, Villas C
Foot Ankle Surg 2021 Feb;27(2):143-149. Epub 2020 Apr 18 doi: 10.1016/j.fas.2020.03.012. PMID: 32370948
CT-guided radiofrequency ablation of osteoid osteoma: established concepts and new ideas.
Singh DK, Katyan A, Kumar N, Nigam K, Jaiswal B, Misra RN
Br J Radiol 2020 Oct 1;93(1114):20200266. Epub 2020 Jun 24 doi: 10.1259/bjr.20200266. PMID: 32520586Free PMC Article
Clinical and Quantitative MRI Perfusion Analysis of Osteoid Osteomas Before and After Microwave Ablation.
Kostrzewa M, Henzler T, Schoenberg SO, Diehl SJ, Rathmann N
Anticancer Res 2019 Jun;39(6):3053-3057. doi: 10.21873/anticanres.13439. PMID: 31177148
Benign tumors of the spine.
Thakur NA, Daniels AH, Schiller J, Valdes MA, Czerwein JK, Schiller A, Esmende S, Terek RM
J Am Acad Orthop Surg 2012 Nov;20(11):715-24. doi: 10.5435/JAAOS-20-11-715. PMID: 23118137

Recent systematic reviews

Radiofrequency ablation for spinal osteoid osteoma: A systematic review of safety and treatment outcomes.
Sagoo NS, Haider AS, Chen AL, Vannabouathong C, Larsen K, Sharma R, Palmisciano P, Alamer OB, Igbinigie M, Wells DB, Aoun SG, Passias PG, Vira S
Surg Oncol 2022 May;41:101747. Epub 2022 Mar 25 doi: 10.1016/j.suronc.2022.101747. PMID: 35358911
Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Odontogenic and Maxillofacial Bone Tumours.
Vered M, Wright JM
Head Neck Pathol 2022 Mar;16(1):63-75. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01404-7. PMID: 35312978Free PMC Article
Arthroscopic management of intra- and juxta-articular osteoid osteoma of the upper extremity: a systematic review of the literature.
Ge SM, Marwan Y, Abduljabbar FH, Morelli M, Turcotte RE
Eur J Orthop Surg Traumatol 2020 Dec;30(8):1333-1344. Epub 2020 Jun 5 doi: 10.1007/s00590-020-02710-6. PMID: 32504238
Osteoid osteoma of the foot and ankle--A systematic review.
Jordan RW, Koç T, Chapman AW, Taylor HP
Foot Ankle Surg 2015 Dec;21(4):228-34. Epub 2015 May 8 doi: 10.1016/j.fas.2015.04.005. PMID: 26564722
Osteoid osteoma treated by percutaneous thermal ablation: when do we fail? A systematic review and guidelines for future reporting.
Lanza E, Thouvenin Y, Viala P, Sconfienza LM, Poretti D, Cornalba G, Sardanelli F, Cyteval C
Cardiovasc Intervent Radiol 2014 Dec;37(6):1530-9. Epub 2013 Dec 13 doi: 10.1007/s00270-013-0815-8. PMID: 24337349

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